척추후종인대 및 황인대골화의 전산화단층촬영술

정남근 대한영상의학회 1986 대한영상의학회지 Vol.22 No.4

Ossification and calcification of the spinal ligaments frequently cause pressure upon the spinal cord and nerve roots. Authors reviewed 150 cases of C-spine CT, 80 cases of T-spine CT, and 725 cases of L-spine CT which were carried out at Pusan National University Hospital for 2 years from May 1983 to May 1985. We analysed 34 cases which showed ossification of posterior longitudinal ligament (OPLL) and ligamentum flavum(OLF) of these 955 cases. The results are follows : 1. The male to female ratio of spinal ligamentous ossification was 26 :8 . The 5th decade group(24,41%) was the most prevalent age group. 4th decade (26.4%), 6th decade(23.52%), 7th decade (11.76), 3rd decade (8.8%), and 8th decade(2.94%) in that order. 2. Of 955 cases of spine CT, incidence of OPLL was 25 cases (2.51%) and that of OLF was 10 cases(1.05%). 3. Regional incidence of spinal ligamentous ossification was as follows. 1) In case of OPLL, cervical area was 19/150(12.67%) and lumbar area was 6/725(0.83% . 2) In case of OLF, Thoracic area was 3-80(3.75%) and lumbar area was 8/725(1.10%). 4. The most frequent length of OPLL was 4 body length (32%) and the most frequent locations are C4 and C5 (68%). The types of OPLL were 15 cases (60%) of segmental type, 8 cases (32%) of continuous type, and 2 cases (8%) of mixed type in that order. All segmental types were degree 1 or 2 and most continuous and mixed type (80%) were degree 2 or 3 dural sac effect. 5. The number of involved interlaminar spaces in OLF was 1 to 5 interspaces and most of OLF were found at low thoracic and lumbar area. 6. There could be noted high correlation between the spinal ligamentous ossification and degenerative discdisease. The incidence of associated disc disease was 18/25(72%) in OPLL and and 8/10(80%) in OLF.

황동볼트 손상원인 분석사례

정남근,Jeong, Nam-Geun 한국열병합발전협회 2002 열병합발전 Vol.30 No.-

According to recent Korea Electric Power Company report, yearly distribution line brass cramp bolts failure summed up to 4,400 cases emerging as one of main local break-down causes. Naturally, the need for the investigation was proposed To determine the root cause of the cramp bolt failures, mechanical and metallurgical investigation were performed for 90 samples which collected from various sites. For the understanding of the geometric characteristics, stress distribution was evaluated by CAE program and proof load of each bolts was tested. The SEM&EDS was used for metallurgical investigation. Through the investigation, the root causes of failures were confirmed. All damaged bolts showed intergrannular fracture mode and the all fractured bolt showed ß phase morphology contrast to the a&ß mixture morphology of the non-damaged samples. Additionally, EDS analysis confirmed the existence of lead rich layer on grain boundaries.

가토 신동맥으로 주입한 Doxorubicin-lipiodol emulsion에 의한 신손상의 조직학적 분포

정남근; 문태용; 이석홍; 이준우; 김창원; 나하연 부산대학교 병원 암연구소 1999 부산대병원학술지 Vol.- No.6

구상흑연주철재의 교체기준 정립을 위한 기계적 강도와 구상화율 의존성평가

정남근(N. K. Jeong),김범수(B. S. Kim),김두수(D. S. Kim),이성호(S. H. Lee) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.8

In this study, we have investigated the causes of failure in tower fitting used in 345㎸ transmission line tower. The tower fitting made of spheroidal graphite cast irons. Microstructural analysis(spheroidal ratio) and measurement of mechanical properties(impact test, tensile test) were performed to clarify mutual relationships among these parameters. The strength of tower fitting was over 30 ㎏f/㎟ except for the flake type morphology of graphite.

배전용 클램프 볼트 손상원이 분석

정남근(N.G. .Jung),김범수(B.S. Kim),김두수(D.S. Kim),이성호(S.H. Lee) 한국동력기계공학회 2002 한국동력기계공학회 학술대회 논문집 Vol.- No.-

비파괴기술을 이용한 발전설비 예측정비 기법 도입과 적용

정계조(Gye-jo Jung),정남근(Nam-gun Jung) 한국비파괴검사학회 2010 한국비파괴검사학회지 Vol.30 No.5

발전회사는 설비 신뢰성과 이용율 저하없이 운영 및 정비비용을 낮추라는 요구를 받고 있다. 설비 운영자는 이러한 요구사항에 부합하기 위하여 현재의 정비기술에 대하여 다시 평가를 하고 있다. 정비비용을 낮추고 효율적인 운영 기간을 늘리기 위하여 설비의 최적 운영상태를 확인할 수 있는 비파괴기술을 이용하여 예측정비 기법을 적용할 수 있다. 예측정비 프로그램에는 내부운영 프로그램과 외부프로그램 그리고 혼용 프로그램이 있으며, 현명한 신뢰 (smart thrust)개념을 사용하면 예측정비 프로그램을 성공적으로 적용할 수 있다. Many forces are pressuring utilities to reduce operating and maintenance costs without cutting back on reliability or availability. Many utility managers are re-evaluating maintenance strategies to meet these demands. To utilities how to reduce maintenance costs and extent the effective operating life of equipment, predictive maintenance technique can be adapted. Predictive maintenance has three types program which arc in-house program, engineering company program and mixed program. We can approach successful predictive maintenance program with "smart trust" concept.

Multiple Infarction과 Small Artery Infarction의 독립적 위험인자로서의 Methylenetetrahydrofolate Reductase Gene Mutation

정정욱,박정미,최병옥,김남근,오도연,정우상,Jung, Jung-Uk,Park, Jung-Mi,Choi, Byung-Ok,Kim, Nam-Keun,Oh, Do-Yeun,Jung, Woo-Sang 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Objective : Hyperhomocysteinemia has been proven to be an independent risk factor for stroke. The genetic mutation of methylenetetrahydrofolate reductase(MTHFR) elevates serum homocysteine level, but it still remains controversial whether the MTHFR gene mutation could be a predictor of ischemic stroke. Therefore, we studied if this genetic defect could cause ischemic stroke independently. Methods : We gathered ischemic stroke subjects and age, sex-matched controls. Age, gender, past medical history, smoking habit, serum homocysteine level, and the MTHFR genotype were recorded. General characteristics of ischemic stroke subjects were compared to the controls. We classified the stroke according to the related vessels(small and large artery infarction) and single lesion and multiple infraction. Relevant risk of the MTHFR genotype was evaluated in each stroke subtype with multiple logistic regression analysis. Results : When the controls were compared to the whole ischemic stroke, there was no specific difference except some medical histories. However, further analysis based on stroke subtypes showed important results. The small artery infarction group, multiple infraction group had significant odds ratio of the MTHFR TT genotype adjusted for age, gender, medical history and smoking habit. Conclusions : The MTHFR TT genotype is an independent risk factor for certain types of ischemic stroke, small artery infarction and multiple infarction.

한국어 피동구문에 관한 제약기반적 접근

이남근 ( Nam Geun Lee ),정병균 ( Byung Gyoon Chung ) 조선대학교 인문학연구원 2002 인문학연구 Vol.27 No.-

The main purpose of this paper is two-fold: Firstly, we summarize the arguments that ey/eykey-phrase in Korean passives is an adjunct, not an optional complement and to analyse the passive constructions on the basis of hypotheses of Bouma, Malouf & Sag(1998). Passive type in Korean has its two subtypes such as short-form passive, and long-form passive. And they are constrained according to their distinct properties. And also the postpositional phrase, ey/eykey phrase, has been treated as adjunct in previous studies so far: Kiparsky (1987), Grimshaw (1990), Wechsler (1995) and Jo & Chung (2001). Secondly, we present the various mechanisms within the framework of HPSG, especially Manning & Sag (1998), Bouma, Malouf & Sag (1998), introduce the specific constraints on our passive types in Korean, and then formulate the passive type hierarchy. (Chosun University)

Metallurgical Failure Analysis on a Suspension Clamp in 154kV Electric Power Transmission Tower

이재홍,정남근,Lee, Jaehong,Jung, Nam-gun Korea Electric Power Corporation 2021 KEPCO Journal on electric power and energy Vol.7 No.2

Failure of a suspension clamp made of hot dip galvanized cast iron in 154kV transmission tower was investigated. Metallurgical analysis of a crack of the clamp was performed using a digital microscope, an optical microscope, and a scanning electron microscope. It was revealed that the crack surface was covered by continuous zinc layer. Distinctive casting skin was found underneath both the outer surface and crack surface. The result showed that pre-existing crack had been formed in the fabrication, and liquid metal embrittlement during hot dip galvanization may assist crack propagation.

구연 : 제한효소분절질량다형성(RFMP)을 이용한 라미부딘 내성 B형 간염바이러스의 검출

황성규,김남근,한진희,김형태,고광현,홍성표,박필원,임규성,정현재,지미선,김은옥,문명순,이환석,김석준,유왕돈,김수옥,홍선표 대한간학회 2003 Clinical and Molecular Hepatology(대한간학회지) Vol.9 No.3(S)

배경/목적: 만성B형간염의 치료에 사용되는 뉴클레오사이드 유도체인 라미부딘은 지속 사용시 B형간염바이러스(HBV)의 중합효소인 P 유전자에 돌연변이를 유발하게 되는데, 중합효소의 활성 부위인 tyrosine, methionine, aspartate, aspartate (YMDD) motif의 M552I (YIDD)와 M552V (YVDD)가 내성을 유발하는 주요 돌연변이로 보고되고 있다. 현재 제한효소분절길이다형성(RFLP), 염기서열분석 및 hybridization (LiPA) 방법이 내성 바이러스의 분석에 활용되고 있으나, 1) 야생형과 변이형 혼합감염의 진단이 어려운 점 (RFLP, 염기서열분석, LiPA), 2) 임상적 응용 범위가 협소한 점(RFLP), 3) 분석 기술의 사용이 불편한 점 (RFLP, 염기서열분석), 4) 새로운 변이의 동정이 어려운 점(RFLP, LiPA), 5) 고비용(염기서열분석, LiPA)의 문제점으로 인해 임상적 사용이 크게 제한을 받고 있는 실정이다. 본 연구는 자동화 말디토프 (MALDI-T) 질량 분석 기술을 응용한 제한효소분절질량다형성(Restriction Fragment Mass Polymorphism, RFMP) 방법을 이용하여 내성 바이러스의 검출과 새로운 변이형의 동정을 대용량으로 정확하게 수행할 수 있는 지의 여부를 알아보고자 하였다. 대상과 방법: Type IIS 제한효소의 인지 부위를 포함하며 HBV P 유전자의 YMDD motif의 upstream에 결합하도록 제작된 특수 시발체(primer)를 이용하여 중합연쇄반응(PCR) 반응을 하고, 해당 제한효소로 절단하게 되면, YMDD motif를 포함하는 7mer와 13mer의 올리고머가 형성된다. 이 두 가지의 올리고머 (allele-diagnostic fragments)는 YMDD motif에 출현하는 돌연변이의 종류에 따라 특정 질량을 가지게 되는데, 이 두 분자의 질량을 말디토프 질량분석기에서 측정함으로써 바이러스의 변이를 파악하게 된다. 결과: RFMP 방법의 검출한계와 야생형과 변이형 바이러스가 공존할 때의 식별능력을 분석하였을 때, 야생형 중에 변이형의 비율이 0.1% 미만일 때, 그리고 혈청 1mL 당 HBV 게놈이 100 copies까지도 유의하게 변이 바이러스를 검출하였다. 기존 방법인 RFLP와 sequencing으로 HBV 변이형이 동정되었던 환자 20명의 혈청을 RFMP 방법으로 분석한 결과, 정확성 외에도 바이러스 breakthrough 6개월 전에 변이 바이러스의 출현을 조기 검출할 수 있었다. 또한 RFLP 방법에 의해 검출하지 못한 새로운 바이러스 변이들을 검출하였고 중복 감염시 혼합 바이러스 간의 상대적 양을 파악할 수 있었다. 결론: RFMP 방법은 높은 정확도, 민감도, 변이 바이러스 특이도 및 중복 감염 바이러스의 상대량 분석능력을 갖는 새로운 내성바이러스 검출 방법으로 대량의 임상 샘플을 신속한 처리가 가능하므로 라미부딘 및 항바이러스제 치료 예후 및 질환 경과의 임상적 이해에 활용되길 기대한다.