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임영석,이준행,박동영,김범,백경란,김성민,권오정,송재훈 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1
저자들은 53세 남자로서 파키스탄을 여행한 직후 열대열원충으로 인한 뇌형 말라리아가 발병되어 혼수에까지 이르렀고, 적절히 치료하였으나 뇌기저핵의 경색과 신경학적 휴우증을 남겼던 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. In recent years, the incidence of imported cases with falciparum malaria has been increasing in Korea due to marked increase in travel to malarious area without adequate prophylaxis. Cerebral malaria is and encephalophaty which can complicate some patients infected with Plasmodium falciparum leading to significant mortality. We report a case of 53 year-old male with cerebral malaria who was thought to be infected in Pakistan. Blood smear showed typical intra-erythrocytic ring form trophozoites and banana-shaped gametocytes of P. falciparum. The patient had been in comatose state for a week despite immediate treatment with meloquine. After improvement of his consciousness, however, aphasia and quadriparesis persisted and brain MRI showed subacute infarction of both basal ganglia (globus pallidus and putamen). To our knowledge, this is the first case of cerebral malaria complicated with cerebral infarct reported in Korea.