천연 황색색소 생성을 위한 Monascus sp 변이주 분리 및 특성

이호재,허성호 동의공업대학 1998 論文集 Vol.24 No.1

A yellow pigment producing mutant Monascus sp. Y7 was derived from KCCM 11832 stram(Monascus anka Nakazawa et Sato IFO 4478) by natural selection, UV irradiation and MNNG(N-methyl-N'-nitro-N-nitrosoguanidme) treatment. The mutant produced only yellow pigment extraceilularly unlike its parents. Its productivity of yellow pigment was 2.2 times high than that of parents. Produced yellow pigment showed characteristics of maximum adsorption at 373nm and dissolved in polar solvent like as water and ethanol.

실용적인 맥파변환기 개발

이호재 가톨릭상지전문대학 1997 논문집 Vol.27 No.1

This paper describes a development of two-model transducers(radial pulse wave transducer and carotid pulse wave transducer) for non-invasively detecting radial pulse wave and carotid pulse wave which need to study arterial pulse diagnosis of korean traditional medicine. This transducer can detect continuity in real time arterial pulse wave and it can use semipermanent for a long time. The mechanism of transducer is composed of sensing mechanism, pressure sensor. The variation of arterial pulse pressure in sensing mechanism is converted to the electric signal by piezo-resistive pressure sensor and it converted to the digital signal after preprocessing via ADC. The developed transducers be made an clinical experiment in analyzing a operation features, in detecting a valid component of arterial pulse wave. As the results, it is found that is superior to operation feature and that is a feature parameters in arterial pulse wave which detected by the developed transducer. This transducer can be helpful in quantify the aterial pulse diagnosis of the korean traditional medicine.

액상요구르트의 沈澱安定化를 위한 硏究

양지영,이호재 釜山工業大學校 1994 論文集 Vol.36 No.-

In order to process the liquid yogurt without stabilizing agents, addition of rice bran extracts to medium, single or mixed cultures of various lactic acid bacteria were investigated. Addition of rice bran extracts stimulated acid production and propagation of L. casei N.Y. and its optimum concentration was 0.1%. Cultures prepared using 0.1% of rice bran extracts could be produced stable liquid yogurt product without stabilizing agents. But the use of rice bran extracts to liquid yogurt manufacture in a pilot scale was problematical in view of cost and law. The single or mixed cultures of L.casei L-14 and L. bulgaricus B-5b couldn't be produced stable product without stabilizing agents. L. casei J.Y. was produced 2.7 of acidity at 37℃ for 36 hrs to obtain cultures with high acidity and high number of viable cells. The liquid yogurt product prepared using cooled cultures of L. casei J.Y. was stable without stabilizing agents. But the liquid yogurt product prepared using stabilizing agents was unstable because of charge imbalane.

Monascus sp. 면이주 Y7이 생성하는 황색색소의 특성

이호재 동의공업대학 1999 論文集 Vol.25 No.1

Characteristics of yellow color produced by Monascus sp. Y7, mutant of Monascus anka Nakazawa et Sato IFO 4478, was studied. The extracted color was stable in wide range of pH, heat, and UV light, whereas relatively unstable in sunlight. The stability of yellow color was not changed by adding the various metal ions of 10^(-3)M concentration, however, it was somewhat unstable by adding the Ca^(++) and Cu^(++). Yellow degree(b/a of Hunter's color value) of mutant color was similar to those of other natural yellow colorants such as annatto, gardenia yellow and carthamus yellow. Thus it may be concluded that yellow color of mutant Y7 is useful food additives as the alternative natural colorant.

종합 한방용 생체정보 검출시스템 구현

이호재 가톨릭상지대학 사회개발·산업기술연구소 1999 論文集 Vol.29 No.-

본 연구는 한의학의 진단과 치료를 과학적으로 객관화하기 위하여 필요한 생체신호들을 통시에 검출하고, 이를 가시화 및 데이터 베이스화하여 특징추출 및 정량화할 수 있는 생체신호처리 및 분석시스템을 구현하였다. 한방의 객관화를 위해 필요한 생체신호는 심전도, 관전도, 맥파(인영맥파, 촌구맥파), 체음도, 호흡도, 심박동수, 호흡수로 하였다. 시스템구성은 변환기부, 하드웨어부, 소프트웨어부로 구현하였다. 변환기부는 심전도/근전도를 검출하기 위한 표면전극, 맥파를 검출하기 위한 맥파변환기, 체음도를 검출하기 위한 체음변환기 및 호흡도를 검출하기 위한 호흡변환기를 구현하였다. 하드웨어부는 변환기 구동회로, 증폭기 및 필터로 구성된 생체신호 검출모듈, A/D변환기 및 컴퓨터로 구성하였다. 소프트웨어부는 신호 입출력, 데이터 처리, 데이터 베이스, 환자 진단정보 및 환자 모니터 메뉴로 구성하였다. 본 연구에서 개발한 시스템의 유효성을 입증하기 위하여 한방 전문가와 함께 임상실험을 통하여 시스템의 평가실험을 한 결과 만족할만한 결과를 얻었다. This paper represents the new system that scientifically and objectively implements diagnoses and treatments dependent on five sensory organs of herb doctors in korean traditional medicine. At first, variable biosignals are detected at the same time and then inputted into a computer system for building visualization and database system. Also, the proposed system makes diagnostic standard convenient to be developed through feature extraction and quantitative analysis. The biosignals used for the proposed system are ECG, EMG, carotid pulse, radial pulse, PCG, RCG, heart rate and respiratory rate. The system is composed of transducer part, hardware part and software part. The transducer part is composed of surface electrode for detection of ECG/EMG, carotid transducer for detection of carotid pulse, radial transducer for detection of radial pulse, body-sound transducer for detection of PCG and respiration transducer for detection of RCG. The hardware part is composed of biosignal detection module, A/D converter and computer. The software part is composed of signal input output menu, database menu, patient diagnostic information menu, and patient monitor menu. We are estimated in order to prove efficiency of the proposed system from an three korean traditional medical specialist.

공동탐사 시스템의 비교에 관한 연구

이호재,조병서,허웅,김현중 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

In this study, we report the characteristics of three Kinds of Radar Exploration Systems, which are used in geological cavity detection, for effective use. The systems are RAMAC, PEMSS and KAIST CW. We repeated measurements each system for same geological model. The AMAC System has a unique capability in finding fracture zones from the reflected waves, and represents the cavity as a hyperbola because the cavity responds as a point source. In the PEMSS systems the relative velocity and attenuation of the electromagnetic wave which varies by geological medium represents geological structures. The main merit of the PEMSS system is cavity localization. The location of the cavity is determined the depths of cavity signals in each offset data. The KAIST CW system also detects a cavity from the attenuation pattern of continuous waves. This uses the phenomenon of 180'phase change of the wave when it propagates the cavity, producing the high attenuation at that point. Our study shows that the RAMAC is suitable in cavity scanning, the PEMSS is adaptive in precise geology exploration, and KAIST CW is best in cavity detection.

노년층을 위한 건축계획의 조명 및 색채에 관한 연구

宋秉夏,이호재 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-

Lifht is an important consideration in environmental design. It constantly changes, and changes in light indicate, among others, the presence or absence of shadow, changes in depth, and a number of cues that subconsciously affect how built-environment user moves through and uses space. Color is another vital factor. The interaction of light and color can provide information on depth, distance, emotional tone of the space, practical use of the space, and even the appropriate rate of movement. Simply put, these two elements provide an abundance of information, including the critical, to the environment user. This study examines these elements in planning mainly the interior space for the elderly whose problems include a reduction in the ability to differentiate color, as well as a diminished ability to perceive contrast and to interpret depth cues.

기종성 신우신염의 임상양상 및 사망위험인자

조수연,이호재,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Emphysematous pyelonephritis (EPN) is an acute gas forming necrotizing infection of the renal parenchyma with high mortality. Although its incidence is relatively low, it mostly occurs in patients wiith diabetes mellitus. The aim of the study is to identify the risk factors related to mortality and assess the outcome of managements according to the radiologic classification. Materials and Methods : The clinical records of 23 patients diagnosed with EPN were reviewed retrospectively. The cases were grouped into two types on the basis of computed tomography scan. Type 1 EPN was defined as renal necrosis and gas formation with total absence of fluid content. Type 2 EPN was defined as the presence of renal or perirenal fluid in association with bubbly or loculated gas pattern. The patients' symptoms, performed investigations, and treatments were analyzed. Results : All patients had diabetes mellitus. Escherichia coli (78.6%) was the most common pathoqen in urine and blood cultures. The factors showing statistically significant differences between survivors and non-survivors were age (P=0.013), the presence of obstructive uropathy (P= 0.008), and type 1 group (P=0.030). Multivariate logistic regression showed that factor significantly related to death was age (odds ratio=1.20, 95% confidence interval 1.01-1.38, P=0.037). Conservative treatment including antibiotics and percutaneous drainage was successful in type 2 group, Overall mortality was 26.1%; all expired patients were from type 1 group. The mortality of conservative treatment and nephrectomy in type 1 group was 83.3% and 20.0%, respectively. Conclusion : These results suggest that old age is a significant risk factor for mortality in patients with EPN. Nephrectomy should be considered as the main treatment option in patients with type 1 EPN.

쑥뜸의 연소특성과 전기쑥뜸기 시스템 개발에 관한 연구

양승열,박영배,이호재,허웅 明知大學校 産業技術硏究所 1994 産業技術硏究所論文集 Vol.13 No.-

In this paper, we study about moxa combustion characteristics and implemented electric moxa cure system which have same effect as a real moxa cure system which have same effect as a real moxa. For this purpose,we analyzed moxa combustion characteristics and then,devised the electrical moxa cure system by using the obtained results. The electrical moxa cure system consist of a thermal stimulating part (heater, themal sensor). and amplifier, A/D converter, PWM power controller, and a computer system. As a result of the experiments. it shows very simular stimulation patterns that a real moxa.

펄스 옥시미터 시스템 구현에 관한 연구

유동주,허 웅,김근이,이호재,임현수 明知大學校 産業技術硏究所 1992 産業技術硏究所論文集 Vol.11 No.-

In this paper, we implemented a pulse oximeter system which is measured oxygen saturation coefficient of a human blood in vivc We use the Beer-Lambert Law to measure the percentage of hemoglobin is oxygen saturation. The oximeter sensor are consisted of two LED(RED and INFRARED LED) and a single photodiode. The photodiode measures lights which transmitted through the tissue from two light source alternately, We calculated a ratio of light transmittance between two LEDs and then, it applied for the oxygen saturation coefficient calculation to formula. As a result, the oxygen saturation coefficient that measured from normal conditions men was 96.43[%]