감초 지표성분 분석법 확립 및 liquiritigenin의 함량 증대를 위한 감초의 수치에 관한 연구

이종록,조미정,박상미,김상찬,박숙자,Lee, Jong-Rok,Jo, Mi-Jeong,Park, Sang-Mi,Kim, Sang-Chan,Park, Sook-Jahr 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.1

Objective : Licorice has been used for treating digestive disorder and also recommended as a detoxification agent. Liquiritigenin, a component of licorice, has been reported to have various biological activities. In this study, we aimed to establish the analytical method for liquiritigenin content in licorice and the processing method for the enhancement of liquiritigenin content in licorice. Methods : Processing was accomplished by roasting licorice at $250^{\circ}C$ for indicated time periods (5-20 min). Analysis of liquiritigrnin from roasted licorice was conducted using UPLC(Ultra Performance Liquid Chromatography). Results : We established UPLC method for the analysis of liquiritigenin using water : acetonitrile gradient as mobile phase. Furthermore, we standardized the processing condition of licorice to enhance liquiritigenin content using UPLC method. Processing of licorice was accomplished by roasting at $250^{\circ}C$ for indicated time periods (5-20 min) and by pretreating with 50% of acetic acid or 30% ethanol for 24 h. By roasting licorice, the liquiritigenin contents in the licorice were increased. The best roasting time of licorice was 6 min, while roasting for the time above 8 min resulted in diminishing liquiritigenin contents. Moreover, pretreatment with 50% of acetic acid or 30% ethanol picked up liquiritigenin contents in roasted licorice. Conclusion : The adequate processing condition of licorice for the enhancement of liquiritigenin contents was obtained by pretreating licorice with 50% of acetic acid or 30% ethanol for 24 h and then by roasting at $250^{\circ}C$ for 6 min.

현호색(玄胡索)과 초초현호색(醋炒玄胡索)의 여드름균에 대한 항균효과 비교

이종록,박숙자,김영우,조일제,변성희,김상찬,Lee, Jong-Rok,Park, Sook-Jahr,Kim, Young-Woo,Cho, Il-Je,Byun, Sung-Hui,Kim, Sang-Chan 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.3

Objectives : Corydalis tuber has been used for promoting blood circulation and for relieving pain in Oriental medicine. In the present study, we focused on the antimicrobial activity of Corydalis tuber and compared its antimicrobial activity with the processed Corydalis tuber. Methods : Processing of Corydalis tuber was accomplished by immersing in 5% of acetic acid for 12 h and then by roasting at $250^{\circ}C$ for indicated time periods(0-30 min). Minimum inhibitory concentration(MIC) and the zone of growth inhibition were determined against Propionibacterium acnes(P. acnes). Results : The methanolic extracts of Corydalis tuber showed potent antimicrobial effect(MIC 62.5 ${\mu}g/ml$). Its alkaloidal component, dehydrocorydaline, also exhibited antibacterial activity(MIC 25.0 ${\mu}g/ml$). After processing of Corydalis tuber, its inhibitory effect on the growth of P. acnes was significantly enhanced compared with that of unprocessed Corydalis tuber. Furthermore, elevated content of dehydrocorydaline was found in the processed than the unprocessed Corydalis tuber. However, the different roasting minutes effected on antimicrobial activity. The best roasting time of Corydalis tuber was 10 min, while roasting for the time above 15 min resulted in diminishing antimicrobial activity. Thus, it was concluded that the standardized processing condition of Corydalis tuber should be established to obtain enhanced antimicrobial(P. acnes) activity. Conclusion : For antimicrobial effect against P. acnes, the best processing condition of Corydalis tuber is immersing in 5% of acetic acid for 12 h and by roasting at $250^{\circ}C$ for 10 min.

국어교육과 학교도서관

이종록,Lee, Jong-Rok 한국도서관협회 1966 圖協月報 Vol.7 No.1

쑥갓 잎에서 터펜노이드계 화합물의 분리 및 동정

이경동 ( Kyung Bong Lee ),하태정 ( Tae Joung Ha ),이병원 ( Byong Won Lee ),이종록 ( Jong Rok Lee ),이준 ( Jun Lee ),황선우 ( Sun Woo Hwang ),조동령 ( Dong Young Cho ),남상해 ( Sang Hae Nam ),양민석 ( Min Suk Yang ) 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.1

Three terpenoids were isolated from the leaves of Chrysanthemum coronarium L. by silica gel chromatography and recrystalization. The structure of compounds 1, 2, and 3, using various spectroscopic data, were identified as to be terpenoid derivatives of dihydrotulipinolide, loliolide, and 5α, 8α-peroxyergosterol, respectively. The presence of these 3 is the first time reported in this plant. The cytotoxic activity of 5α, 8α-peroxyergosterol showed strong activities against human cancer cell lines such as A549, PC-3, and HCT 116.

십일조로 이루는 샬롬 - 신 26:12-15를 중심으로: 십일조로 이루는 샬롬

이종록(Lee Jong-Locke) 한신대학교 신학사상연구소 2006 신학사상 Vol.0 No.132

  신명기 법전은 이스라엘 백성들이 그때까지 지방성소에 바쳤던 모든 예물들을 그 이후로는 중앙성소에만 바치도록 규정한다. 그리고 드리는 예물들을 사회적으로 어려운 사람들과 함께 나누게 하는데, 여러 예물들 가운데서 특히 십일조가 그런 역할을 담당했다. 이런 점에서 십일조는 고대 이스라엘 사회에서 샬롬을 실현하는 중요한 방편이었다.   신명기에서 십일조에 대해 이야기하는 본문은 12장, 14장, 그리고 26장인데, 14장과 26장은 12장과 달리 "셋째 해에 드리는 십일조"를 언급한다. 그런데 이것은 신명기 내에서도 특별한 규정일 뿐만 아니라, 구약성서 다른 곳에서는 찾아볼 수 없는 규정이라는 점에서 독특성을 갖는다.   In the book of Deuteronomy, we can find the phrases about the tithe in ch. 12, 14, and 26. Ch. 12 is different from ch. 14 and 26 which say about the tithe of the third year. This rule about the tithe of the third year is very special, because we can not meet this rule except in the book of Deuteronomy. The ancient Israelites collected the third year tithes and stored them at their local temples in order to help the helpless living in their cities. As we know, during the reformation of the king Hezekiah and the king Josiah, the ancient Israelites dislike and destroy their local shrine. Therefore, this is very dangerous for the Israelites to collect their tithes at their local shrines in order to help the helpless. This rule may make the system of the central shrine as powerless. But in spite of this dangerous result, they kept the rule.   The book of Deuteronomy tells about the ancient Israelites who wanted to realize shalom through the offerings, especially the tithes. The ancient Israelites made the official organizations for excercise their thoughts in the Deuteronomic Code, in order to distribute their offerings to the Levites and the poor through the whole country.

대두, 홍삼, 진피로 구성된 발효 추출물의 항염증 효능에 관한 연구

이종록 ( Jong Rok Lee ),김영우 ( Young Woo Kim ),변성희 ( Sung Hui Byun ),김상찬 ( Sang Chan Kim ),박숙자 ( Sook Jahr Park ) 대한본초학회 2015 大韓本草學會誌 Vol.30 No.5

Objectives: Fermentation of herbs has been known to be helpful in improving the immune systems and protecting body against disease. The present study was conducted to evaluate anti-inflammatory effects of the fermentation extracts (FE) consisting of soybean, red ginseng and Citrus Unshiu Peel in lipopolysaccharide (LPS) -activated Raw264.7 cells. Methods: FE were prepared by the fermentation with Bacillus Subtilis and then by extraction with ethanol (95%; prepared by the fermentation process). Cell viability was measured by MTT assay. Nitric oxide (NO) production was measured in culture media by Griess assay. The expression of nuclear factor (NF)-κB and inhibitory kappa B alpha (IκBα) was determined by Western blot. Results: LPS-induced production of NO and PGE2 was dose-dependently decreased by the treatment of FE in Raw264.7 cells. These suppressive effects of FE on NO and PGE2 production were related to the inhibition of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. FE inhibited LPS-induced production of pro-inflammatory cytokines, TNF-α, IL-6, and IL-1β in a dose-dependent manner. Furthermore, FE inhibited the NF-κB signaling pathway through the prevention of LPS-induced degradation of IκBα in cytosol and the nuclear translocation of NF-κB. Conclusions: These findings suggest that FE could have anti-inflammatory effects on LPS-induced inflammatory responses in macrophages.

18세기 경주김씨(慶州金氏) 학주공파(鶴洲公派)의 대두와 기호학계에서의 위상

이종록 ( Lee Jong-rok ) 한국계보연구회 2021 한국계보연구 Vol.11 No.-

이 글은 서산 大橋[한다리]에서 세거했던 경주김씨 학주공파의 부상과 이를 가능하게 했던 動因을 遡及하여 분석한 것이다. 이들은 경주김씨 내에서 대안군파, 태사공파, 좌랑공파, 장단공파를 이어 학주공파로 분파되었다. 이들을 기록한 족보는 태사공파의 후손을 기록한 1685년(숙종 11)의 乙丑譜와 1784년(정조 8)의 甲辰譜가 있다. 족보 편수의 본래적 목적인 世系의 정비에 을축보가 김자수-김세필로 이어지는 사림 표방을 강조하고자 한 것이라면, 갑진보는 왕실의 일원임을 드러내고자 한 것이었다. 경주김씨 태사공파의 족보 간행을 둘러싼 수보 목적의 변화는 가문 내 중심축의 변화가 선행한 것이었고 동시에 정순왕후의 왕비 간택을 계기로 촉발된 학주공파의 대두가 존재했다. 하지만 단순히 왕후의 등장이 곧 그러한 변화를 가능케한 것은 아니었다. 당시 정순왕후의 至親들은 정치적으로 南黨-僻派을 조직하고 학문적으로는 湖論의 주요한 역할을 담당하였다. 남당이 자립할 수 있었던 까닭은 정순왕후의 후원 외에도 호론의 학문적 조력이 있었기에 가능한 것이었고, 여기에서 金漢祿의 역할이 두드러진다. 김한록은 호락논쟁이 격화되는 시기에 호론의 종장 韓元震에게 수학하였다. 김한록은 한원진에게 호론의 학문적 정체성을 물려받았고, 점차 호론의 중심적 역할을 담당하는 위치로 나아갔다. 하지만 호론은 주요 학자들의 사후 학통의 전수를 지속하지 못하였고, 김한록이 사후 八字凶言으로 충역 시비에 휘말리면서 벽파에 속하던 경주김씨들이 연좌되었다. 이는 벽파와 호론이 역사적 흐름에서 단절된 사건이기도 하였다. 수면 아래로 가라앉았던 호론이 역사 속에 재등장한 것은 일제의 침략이 가시화되는 근대전환기에 이르러서였다. 1895~1896년 홍주에서는 홍주의병이라는 반개화·반침략 반일투쟁이 일어났는데, 이때 의병의 이념적 기반이 호론에 근거한 것이었다. 이때 의병을 주도한 金福漢, 金商悳, 李偰 등은 모두 호론을 계승했다는 의식을 담지하고 있었는데 학통에 있어서 호론의 적전으로 김한록을 지목하였다. 이는 내포지역을 중심으로 형성되었던 김한록의 호론 내의 위상이 비로소 추인된 것이라 할 수 있다. This article analyzes the emergence of of Kim Hong-wook of Gyeongju Kim Clan, who lived in Daegyo, Seosan, and the key motivation that made it possible. They were divided into Hakjugong-pa following the Daeangun-pa, Taesagong-pa, Jwaranggong-pa, and Jangdangongpa within Gyeongju Kim Clan. Eulchukbo in 1685 (the 11th year of King Sukjong's reign), which recorded the descendants of Taesagong-pa, and Gapjinbo in 1784 (the 8th year of King Jeongjo's reign) are the genealogical records of Gyeongju Kim Clan. If Eulchukbo had an intention to emphasize the advocacy of Sarim leading to Kim Ja-su and Kim Se-pil in terms of the original purpose of organizing genealogy, the purpose of organizing Gapjinbo was to reveal that it was a part of the royal family. The change in the purpose of organization surrounding the publication of genealogical records by Gyeongju Kim Clan’s Taesagong-pa was due to the change in the central force in the family, and simultaneously, the rise of Hakjugong-pa, triggered by selection of a spouse for the Royal family-the royal family’s selection Queen Jeongsun-had a great influence. However, simply the appearance of the Queen did not make such a change possible. At that time, Queen Jeongsun's close relatives politically organized Namdang-Byeokpa and academically, played a major role in Horon. The reason why the Namdang was able to stand on its own feet was because of the academic assistance of Horon in addition to the support of Queen Jeongsun, where Kim Han-rok's role stands out. Kim Han-rok studied with Han Won-jin, the instructor of Horon, at a time when the Horak debate was intensifying. Kim Han-rok inherited the academic identity of Horon from Han Won-jin, and gradually moved to a position that plays a central role in Horon. However, Horon failed to continue the transfer of scholarship after the death of major scholars, and Gyeongju Kim Clan, who belonged to Byeokpa, was taken over as Kim Han-rok was embroiled in a dispute over the loyalty with the "Eight letters of curse[Palja Hyung-eon 八字凶言]" after his death. This was also an event in which Byeokpa and Horon were cut off from historical stream. Horon, which had subsided below the surface, reappeared in history when the Japanese invasion became visible. From 1895 to 1896, an anti-Japanese struggle broke out in Hongju under the banner of anti-enlightment and anti-invasion called the Hongju Righteous Army. Kim Bok-han, Kim Sang-deok, and Lee Seol, who led the righteous army, all had a sense of inheriting Horon, and they pointed out Kim Han-rok as the heir of Horon in terms of academic background. This can be said that Kim Han-rok's status within the horon was formed around the Naepo area, and that status was finally confirmed.

예언과 시뮬라크르: 시뮬라크르 개념으로 살펴보는 에스겔서 40-48장의 환상

이종록(Lee Jong-Lock) 한신대학교 신학사상연구소 2011 신학사상 Vol.0 No.154

이 논문은 에스겔서 40-48장에 나오는 환상의 방식과 성격을 새로운 각도에서 살핌으로써 그 문학유형을 명확하게 규정하는데 목적을 두는데, 이를 위해서 ‘시뮬레이션’(simulation)과 ‘시뮬라크르’(simulacre) 개념을 사용할 것이다. 그리고 이러한 작업을 통해서, 에스겔서 40-48장에 나오는 환상(vision)이 환상(fantasy)이며, 그래서 에스겔서 40-48장이 “환상문학”임을 밝힐 것이다. 에스겔서 40-48장은 구약성서에서 대표적인 환상문학이다. 여러 학자들이 본문의 장르를 규명하기 위해서 많은 노력을 기울였는데, 지금까지의 에스겔서 40-48장에 대한 연구는 말할 것도 없고 현재의 연구 작업들도 우리가 사는 디지털 시대를 염두에 두지 않았다는 한계를 보인다. 그리고 환상문학 연구에 필요한 철학과 예술에 대한 현대적 논의를 전혀 고려하지 않았다. 지금까지 학자들은 에스겔서 40-48장을 단순하게 “환상보고” 양식이라고 명명함으로써, 이 본문이 다른 환상 본문들과 비교할 때 보여주는 현격한 차이에 주목하지 않았으며, 이 본문에 명확하게 그리고 독특하게 나타나는 환상체험방식과 내용 자체를 깊이 연구하지 않았다. 에스겔서 40-48장이 보여주는 본질적이고 고유한 차이를 드러내고 그것을 보다 정확하게 명명하기 위해서는, 시뮬레이션과 시뮬라크르라는 개념을 통해서 본문을 새롭게 살펴보아야 한다. 에스겔서 40-48장은 가상공간에서 시뮬레이션을 한다는 점에서 “하나님의 이상”(마르오트 엘로힘)을 언급하는 다른 두 본문, 즉 에스겔서 1장, 그리고 8-11장과 매우 상이하며, 이 본문이 묘사하는 환상체험은 기원도 없고 재현물도 없이, 즉 지시대상이 없이 발생하는 순수 사건으로서의 온전한 시뮬라크르이다. 그리고 본문은 환상 속의 환상, 즉 시뮬라크르의 시뮬라크르라를 보인다. 또한 에스겔서 40-48장이 갖는 이런 독특성으로 인해, 본문의 환상(vision)은 환상(fantasy)이며, 그래서 본문은 다른 환상 본문들과는 구별되는 환상문학(fantasy)이기도 하다. 이런 점에서, 이 연구는 앞으로 예언과 환상문학을 연계하는 새로운 연구영역을 확보했다는 데 의미를 갖는다. This paper takes aim at studying the mode and the character of Ezekiel 40-48 from the new angle and defining the literary genre of it. In order to do so, I will adapt the concept of simulation and simulacre. So I will come clean on the fact that the vision of Ezekiel 40-48 is the fantasy, and that Ezekiel 40-48 is the literature of fantasy. Ezekiel 40-48 is the representative literature of vision in the Old Testament. Many scholars have tried to find out the genre of that text, but the studies on that text until now have not considered the fact that our days are very digital. And most of scholars have not considered the discussion about the modern philosophy and the modern art which is useful for the study of the literature of vision. By this time, scholars have named the genre of Ezekiel 40-48 as “vision report.”They have not paid attention to the wide difference between that text and the other vision reports and they have not studied the mode of vision experience and the content of our text thoroughly. In order to expose the essential and proper difference that Ezekiel 40-48 shows and to name it correctly, we should study newly our text by the concept of simulation and simulacre. By the fact that our text shows the skill of simulation in the virtual space, it is very different from Chapter 1 and 8-11 of the Book of Ezekiel that mention about the vision of God. The vision experience that our text describes has no origin and representation of it. Therefore, it is a simulacre as the occurring pure event without referent in reality. And in our text, we can find also the vision of vision, that is, simulacre of simulacre. And because of such peculiarity of Ezekiel 40-48, vision of our text is fantasy, and our text itself is the literature of fantasy that is distinguished from the other texts of vision in the Old Testament. From this view point, this study is very meaningful for securing the new research realm.

카이로프랙틱 치료법이 목통증환자에게 미치는 영향

이종록(Lee, Jongrok),오청욱(Oh, Chung-Uk),이민선(Lee, Min-Sun),서동화(Suh, Dongwha) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.3

본 연구의 배경은 카이로프랙틱 치료가 목통증환자의 관절가동범위와 통증에 미치는 영향을 밝히는 것이다. 연구방법은 만성목통환자 8명, 급성목통환자 8명에게 2013년 4월부터 6월까지 각각 2주간 총 4회 카이로프랙틱 치료 후 관절가동범위와 통증 정도를 비교한 비동등대조군 실험설계이다. 자료는 SPSS 12.0 Version(Window XP)를 이용하 여 분석하였다. 결과는 급성목통환자와 만성목통환자 모두 카이로프랙틱 치료 후 관절가동범위와 통증정도에 있어 유 의한 차이가 있었다(P<.05). 결론은 급성, 만성 목통증 환자를 대상으로 카이로프랙틱 치료를 한 결과 목부위 관절가 동범위와 통증정도가 개선되었으며, 환자들의 삶의 질과 웰빙을 개선하기 위해 이에 대한 후속 연구와 임상에의 적용이 계속되어야겠다. Background: this study examined the Chiropractic therpy's influences on range of motions and pains with patients who have neck pain. Methods: In an experimental study with a two-group(chronic neck pain vs acute neck pain) design, 16 participants were enrolled for 2 weeks, 4 times, from march to april, 2013, with 8 acute neck pain patients and 8 chronic neck pain patients in chiropractic threrapy. Results: after the chiropractic threrapy, range of motions improved and pains were reduced significantly in both acute and chronic neck pain patients(P<.05). Conclusion: the chiropractic threrapy was effective in improving range of motions and reducing pains in persons who have acute and chronic neck pain. Thus, the chiropractic threrapy could be a resource for continuing study and adaptations to enhance the quality of life and well-being of neck pain patients.

高句麗의 東沃沮 정벌과 樂浪郡

이종록(Lee Jong Rok) 한국고대학회 2016 先史와 古代 Vol.49 No.-

『三國志』 등의 사료에 따르면 高句麗가 농사에 적합하지 않은 땅에 위치하여 늘 식량공급 등의 경제적인 문제에 직면해 있었다고 한다. 때문에 고구려는 정복전쟁을 통해 경제적 문제를 해결하려고 하였고, 1세기경의 동옥저 정벌은 그 전쟁의 하나였을 것으로 추정된다. 그런데 동옥저 정벌에 있어서 고구려에게 최대의 장애물은 이미 이 지역에 지배권을 확보하고 있었던 樂浪郡 세력이었다. 따라서 大武神王代 고구려는 정복전쟁은 그 목표가 바로 이들 낙랑군 세력이었을 것으로 본 연구에서는 파악하였다. 고구려는 呑列縣을 비롯한 낙랑군의 縣을 공략하여 동옥저지역의 교통로를 확보하였으며, 그 여파는 낙랑군이 하여금 영동 7현을 방기하는 이유 중 하나가 되었다. 그리고 동옥저에서 군현세력이사라지고 토착 小國들이 서로 相爭하는 기회를 틈타, 고구려는본격적으로 이 지역에 대한 정벌을 추진하였다. 그러나 동옥저에서는 여전히 親漢勢力이자 군의 지배질서를 수용하던 집단이 잔존하고 있었다. 이들은 영동 7현의 방기 이후에도 여전히 樂浪郡의 소속으로써 그 정체성을 보유하고 있던 집단이던 것이다. 따라서 고구려는 이들 친한 세력을 제압하는 방식으로 동옥저 정벌을 수행하였으며, 이것이 사료상에서 樂浪國 이라는 나라와의 전쟁이라는 것이다. 그리고 이후 이들은 낙랑군을 대신하여 토착세력들(渠帥)에게 지배자의 입장에서 조세의 貢納을 받으며 경제적 욕구를 충족했을 것으로 분석하였다. According to historical records such as Sanguozhi(三國志; the Records of the Three Kingdoms), Koguryǒ(高句麗) had constantly suffered economic problems because of its inadequate earth for agriculture. Thus, Koguryǒ used militaristic methods as a solution to their scarcity of provisions, and the invasion into East Okchŏ(東沃沮; Dongokchŏ) was an exemplary case for this mechanism in the first century. The biggest obstacle to Koguryǒ s conquest of East Okchŏ was Chinese Lelang(樂浪) Commandery, which had already secured control over the region using local pro-Chinese groups in East Okchŏ. Consequently, the consistent purpose of King Taemusin(大武神王) s campaigns was to defeat these groups. Koguryǒ attacked Lelang s counties such as Tunlie(呑列縣) to acquire a route to East Okchŏ, and the invasion s aftereffect severed the commandery s direct reign over the region. After Chinese commanderies recession from East Okchŏ, small countries(小國) started quarrels with each other, a situation which allowed Koguryǒ to easily infiltrate into this region. Arguably, the leaders of small countries were the local pro-Chinese groups who kept their identity as a part of Chinese commandery even after the commandery s recession. It was natural that Koguryǒ s aggression targeted at these groups remained in East Okchŏ, since they were potential threats to Koguryǒ s rule over the region. This invasion was described as a war with a kingdom named Lelang(樂浪國; Nangnangguk), supposedly one of the local countries under a pro-Chinese leader. After successfu occupation of East Okchŏ, Koguryǒ adopted a similar method of Chinese commanderies control over the region, as it was the most effect way to satisfy their economic needs.