AlN-Al₂O₃ 계에서의 상압소결 질화물복합체

김영우,김규헌,김동현,윤석영,박홍채,Kim, Young Woo,Kim, Kyu Heon,Kim, Dong Hyun,Yoon, Seog Young,Park, Hong Chae 한국세라믹학회 2014 한국세라믹학회지 Vol.51 No.5

Particulate nitride composites have been fabricated by sintering the compacted powder of AlN and 5 - 64.3 mol% $Al_2O_3$, with a small addition of $Y_2O_3$ ($Y_2O_3$/AlN, 1 wt%), in 1-atm nitrogen gas at $1650-1900^{\circ}C$. The composites were characterized in terms of sintering behavior, phase relations, microstructure and thermal shock resistance. AlN, 27R AlN pseudopolytype, and alminium oxynitride (AlON, $5AlN{\cdot}9Al_2O_3$) were found to existin the sintered material. Regardless of batch composition, the AlN-$Al_2O_3$ powder compacts exhibited similar sintering behavior; however, the degree of shrinkage commonly increased with increasing $Al_2O_3$ content, consequently giving high sintered bulk density. By increasing the $Al_2O_3$ addition up to ${\geq}50 mol%$, the matrix phase in the sintered material was converted from AlN or 27R to AlON. Above $1850^{\circ}C$, a liquid phase was formed by the reaction of $Al_2O_3$ with AlN, aided by $Y_2O_3$ and mainly existed at the grain boundaries of AlON. Thermal shock resistance was superior in the sintered composite consisting of AlON with dispersed AlN or AlN matrix phase.

두개골 성형술의 사용 재료와 수술 시기에 따른 감염율

김영우,유도성,김달수,허필우,조경석,김재건,강준기,Kim, Young-Woo,Yoo, Do-Sung,Kim, Dal-Soo,Huh, Pil-Woo,Cho, Kyung-Suck,Kim, Jae-Gun,Kang, Joon-Ki 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

Objective : Cranioplasty is required to protect underlying brain, to correct major aesthetic deformities, or both. The ideal material for this purpose is autogenous bone. When this is not available, alloplastic or artificial materials may be used. In this study authors compared the infection rate according to the cranioplasty materials(the frozen autologous bone vs. bone cement), and duration of the skull defect. Materials : Between May 1994 and December 1999, 111 patients with skull defect treated with cranioplasty(82 cases of frozen autologous bone and 29 cases of artificial bone material) were included in this study. There were 77 males and 34 females with a mean age of 41.4 years(range 1-85 years). 57 patients had head trauma and 54 had non-traumatic insults. According to the duration of skull defect, there were 28 cases under 1 month, 33 cases of 1-2 months, 15 cases of 2-3 months, 20 cases of 3-6 months and 15 cases over 6 months of duration. Results : Overall infection rate was 9.9%. In cases with frozen autologous bone and artificial bone material, the infection rate was 8.5% and 13.7%, respectively. The infection rate according to the duration of skull defect was 3.6%(among 28 cases) under 1 month of age, while those were 12%(4 among 33 cases) at 1-2 months, 20%(3 among 15 cases) at 2-3 months, 5%(1 among 20 cases) at 3-6 months and 13%(2 among 15 cases) over 6 months. Accoring to the underlying disease, the infection rate in traumatic cases was 12%(7 among 57 cases) and that in non-traumatic one was 3.7%(2 among 54 cases). Conclusion : From this study, it appears that skull defect should be repaired as soon as possible, because early cranioplasty can lower the infection rate. And surgeons could save the patients' cranial bone as possible as they can because autologous bone is not only cost effective in cosmatic purpose but lower the infection rate.

불안정성 흉·요추부 골절에 대한 단 분절 척추경 나사못 고정술 및 추체 보강 성형술 - 예 비 보 고 -

김영우,오성한,윤도흠,진동규,조용은,김영수,Kim, Young Woo,Oh, Sung Han,Yoon, Do Heum,Chin, Dong Kyu,Cho, Yong Eun,Kim, Young Soo 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.11

Objectives : Since vertebroplasty has been introduced, we performed short segment pedicle screw fixation with augmented intra-operative vertebroplasty in patients with unstable thoraco-lumbar fracture. Our intentions are to demonstrate the efficacy and indication of this new technique compare to conventional methods. Material and Methods : The surgery comprised of pedicle screw fixations on one level above and below the fracture site, and the fractured level itself, if pedicle is intact, and intra-operative vertebroplasty under the fluoroscopic guide with in-situ postero-lateral bone graft. Also, in cases of bone apposition, we removed those with small impactor through a transfascetal route. During the last 2 years, we performed in seven(7) unstable thoraco-lumbar fracture patients who consisted of two different characteristics, those four(4) with primary or secondary osteoporosis and three(3) of young and very healthy. All patients were followed clinically by A.S.I.A. score and radiography. Results : Mean follow up period was 14 months. We observed well decompressed state via transfascetal route in cases of bone fragments apposition and no hardware pullout in osteoporotic cases, no poly-methyl-methacrylate (PMMA) leakage through the fracture sites into the spinal canal, and no kyphotic deformities in both cases during follow-up periods. All patients demonstrated solid bony fusion except one following osteoporotic compression fracture on other sites. Conclusions : In the management of unstable thoraco-lumbar fracture, we believe that this short segment pedicle screw fixation with augmented intra-operative vertebroplasty reduce the total length or levels of pedicle screw fixation without post-operative kyphotic deformity.

아데노 바이러스 Cytosine Deaminase/Thymidine Kinase 융합 유전자의 항 종양효과

김영우,최재영,장진우,박용구,정상섭,Kim, Young Woo,Choi, Jae Young,Chang, Jin Woo,Park, Yong Gou,Chung, Sang Sup 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1

Objective : We investigated the feasibility of a double suicide gene/prodrug therapy, involving direct introduction of the herpes simplex virus Type 1 thymidine kinase(TK) gene and the Escherichia coli cytosine deaminase(CD) gene, via a recombinant adenoviral vector and ganciclovir(GCV) and/or 5-fluorocytosine(5-FC) treatment, in C6 glioma cells. Methods : Efficient gene transfer and transduction of C6 glioma cells via a recombinant adenovirus were evaluated by infecting cells with adenovirus bearing the ${\beta}$-galactosidase gene and then staining cells with 5-bromo-4-chloro-3-indolyl-13-D-galactoside. CD/TK expression in cells infected with adenovirus bearing the CD/TK gene(ad-CD/TK) was examined by immunoblotting analysis. For in vitro cytotoxicity experiments, the cells were infected with ad-CD/TK or ad-${\Delta}E1$(as a control). After addition of a variety of concentrations of GCV and 5-FU, either separately or in combination, cell viability was determined by staining the cells with crystal violet solution 6 days after infection. Result : C6 glioma cells were efficiently transduced with recombinant adenoviral vector at multiplicities of infection of 200 or more. In vitro cytotoxicity of GCV and/or 5-FC, either alone or in combination, was exclusively observed in the cells transduced with ad-CD/TK. Obvious cytotoxicity(>50% inhibition) was observed in the presence of 5-FC at concentrations greater than 30ug/ml or GCV at concentrations greater than 0.3ug/ml at a multiplicity of infection of 100. Additionally, cytotoxicity in the presence of both GCV and 5-FC was greater than that after sinlge-prodrug treatments, indicating additive effects of the prodrug treatments. Conclusion : The administration of a double-suicide gene/prodrug therapy might have great potential in the treatment of brain tumors.

형태학적 워터쉐드 알고리즘을 이용한 효율적인 영상분할

김영우,임재영,이원열,김세윤,임동훈,Kim, Young-Woo,Lim, Jae-Young,Lee, Won-Yeol,Kim, Se-Yun,Lim, Dong-Hoon 한국통계학회 2009 응용통계연구 Vol.22 No.4

본 논문은 형태학적 워터쉐드 알고리즘을 이용하여 잡음에 강한 효율적인 영상분할에 대해서 논의하고자 한다. 기존의 형태학적 워터쉐드 알고리즘에 의한 영상분할은 크게 형태학적 연산자에 의한 영상의 단순화, 경사 영상 생성, 워터쉐드 알고리즘 수행 그리고 영역 병합 등의 여러 단계에 걸쳐 이루어진다. 그러나 기존의 형태학적 워터쉐드 알고리즘에 의한 영상분할은 과분할이 많이 일어나는 단점을 갖고 있다. 본 논문에서는 과분할을 줄이기 위해 잡음에 강한 형태학적 연산자에 의한 경사영상을 생성하고 워터쉐드 알고리즘을 적용 후 통계적인 콜모고로프-스미르노프 검정을 사용하여 인접한 영역 간의 픽셀 값 분포를 비교함으로써 부적절한 영역 병합을 최소화하였다. 본 논문에서 제안한 영상분할의 성능을 평가하기 위해 기존의 방법과 정성적이고 정량적인 비교뿐 만아니라 영상분할에 소요되는 계산시간까지 비교하였다. This paper discusses an efficient image segmentation using morphological watershed algorithm that is robust to noise. Morphological image segmentation consists of four steps: image simplification, computation of gradient image and watershed algorithm and region merging. Conventional watershed segmentation exhibits a serious weakness for over-segmentation of images. In this paper we present a morphological edge detection methods for detecting edges under noisy condition and apply our watershed algorithm to the resulting gradient images and merge regions using Kolmogorov-Smirnov test for eliminating irrelevant regions in the resulting segmented images. Experimental results are analyzed in both qualitative analysis through visual inspection and quantitative analysis with percentage error as well as computational time needed to segment images. The proposed algorithm can efficiently improve segmentation accuracy and significantly reduce the speed of computational time.

고령에서 발현한 척수외 혈관모세포종 - 증 례 보 고 -

김영우,김재건,유도성,허필우,조경석,김달수,강준기,Kim, Young Woo,Kim, Jae Keon,Yoo, Do Sung,Huh, Phil Woo,Cho, Kyuong Suck,Kim, Dal Soo,Kang, Joon Ki 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

Intradural extramedullary hemangioblastoma of the spinal cord is uncommon tumor. Symptom onset is typically in the forth decade. Complete excision offers the best chance for cure. We report a case of extramedullary hemangioblastoma of the spinal cord in old age. A 76 -year old man presented with 1 month history of paraparesis. Multiple enhancing lower thoracic and lumbar spinal masses were seen on magnetic resonance imaging(MRI). Surgical exploration for symptomatic lesion revealed intradural-extramedullary mass, which had hypervascularity. The excised spinal masses were diagnosed as hemangioblastoma. Postoperative course was uneventful and symptoms improved gradually.

사상체질진단기준(외모 심성 병증)의 중요도에 대한 연구

김영우,이의주,최선미,정성일,이영옥,조훈석,김종원,Kim, Young-Woo,Lee, Eui-Ju,Choi, Sun-Mi,Jung, Sung-Il,Lee, Young-Ock,Jo, Hun-Seok,Kim, Jong-Won 사상체질의학회 2003 사상체질의학회지 Vol.15 No.3

Purpose: This study had focused on evaluating the QSCC II for the elevating accuracy and the designing new Questionnaire. Methods : QSCC II was administered to 1051 patients who had been treated in the Dong Eui Oriental Medical Hospital and Kyung Hee Oriental Medical Hospital during 19 months from sept. 2000 to mar. 2002. We analyzed all subjects of the QSCC II. Result: 1. In the analysis with all subjects of the QSCC II ,1-1. 75 subjects had a significance between the Sasang Constitution groups. 1-2. In each Sasang Constitution group, we was able to select some significant subjects. I had selected 34 subjects in the Taeyang scale, 33 subjects in the Soyang scale, 28 subjects in the Taeeum scale, and 23 subjects in the Soeum scale. 1-3. When I applied the new intensifying value and calculation, the diagnostic discrimination abilities of the QSCC II was 61.8% about Taeyangin, 55.9% about Soyangin, 63.8% about Taeeumin, 63.6% about Soeumin, and total average was 61.8%.

체질진단분류(體質診斷分類)에 따른 질병(疾病) 및 증상유형(症狀類型)에 관한 임상적(臨床的) 연구(硏究) II (문진표를 중심으로)

김영우,김진원,Kim, Young-woo,Kim, jing-weon 사상체질의학회 1999 사상체질의학회지 Vol.11 No.1

본 연구(硏究)는 1996.3월(月)에서 1998.11월(月)사이에 동의대학교(東義大學校) 한의과대학(韓醫科大學) 부속한방병원(附屬韓方病院)에 내원(來院) 가료중(加療中) 환자(患者) 196명을 대상(對象)으로 하였으며 사상체질(四象體質)의 판별(判別)은 사상변증내용(四象辨證內容) 설문조사지(設問調査紙)(I)과 사상체질분류검사(象體質分類檢査)(QSCCII)를 중심으로 하였다. 본 결과는 사상체질(四象體質)과 질병(疾病) 및 증상유형(症狀類形)에 대한 설문지(說問紙)를 비교하여 얻은 것이다. 1. 태음인(太陰인)은 체중증가(體重增加), 땀이 많이 난다. 몸이 붓는다. 허리가 아프다는 증상(症狀)과 기름진 음식(飮食)을 잘 먹으며 음식(飮食)을 짜게 먹는 편이 다른 체질(體質)에 비하여 더욱 유발(頻發)하였다. 2. 소음인(少陰인)은 안색이 나쁘다. 목의 이물감, 수면장애(睡眠障碍) 식욕감퇴(食慾減退), 쉽게 피로(疲勞)해짐, 식사(食事)와 무관한 위(胃)의 통증(痛症), 두통(頭痛), 생리통증상(生理痛症狀)과 기름진 음식(飮食)을 잘 안 먹는다. 음식(飮食)을 싱겁게 먹는 편이 다른 체질(體質)에 비하여 더욱 유발(頻發)하였다. 3. 통계적(統計的)으로 유의성(有意性)을 가지지는 못하였지만, 소양인(少陽人)은 호흡기계질환(呼吸器系疾患)에서 단순한 기침증상(症狀) 근골격계질환(筋骨格系疾患)에서 관절(關節)의 운동장애(運動障碍), 부인과계(歸人科系)에서 월경(月經)의 조기(調期)와 양(量)의 변화(變化)와 생식기(生殖器) 소양증(搔痒症), 피부계(皮膚系)에서 가려움증과 부스럼증 등은 다른 체질(體質)에 비하여 비교적 많았고 심혈관계질환(心血管系疾患), 혈액계질환(血液系疾患)은 비교적 적었다. 소음인(少陰人)은 전반적(全般的)인 소화기계질환(消化器系疾患), 호흡기계질환(呼吸器系疾患)에서 인흡(咽吸)의 이물감 통증, 심혈관계질환(心血管系疾患), 혈액계질환(血液系疾患), 근골격계질환(筋骨格系疾患)에서 통증(痛症)이나 비증(痺症), 정신신경계질환(精神神經系疾患)에서 정신계질환(精神系疾患), 부인과계(婦人科系)에서 월경통(月經痛)을 비롯한 유방(乳房)의 몽우리 냉증(冷症), 피부계(皮膚系)에서 발진(發疹)이나 두드러기, 시각계질환(視覺系疾患)과 청각계질환(聽覺系疾患)등이 다른 체질(體質)에 비해 많았다. 태음인(太陰人) 호흡기계질환(呼吸器系疾患)에서 목이 잘 쉬는 증상, 근골격계질환(筋骨格系疾患)에서 요통(腰痛), 정신신경계질환(精神神經系疾患)에서 신경계질환(神經系疾患), 피부계(皮膚系)에서 발진(發疹)이나 두드러기등이 다른 체질(體質)에 비하여 다소 많았으며 부인과계질환(婦人科系疾患)은 적었다. The object of this study is 196 patients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center during 33 months from January 1996,3 to June 1998,11. We proceeded the judgment of Sasang Constitution by 'Questionnaire of Sasang Constitution Classification(I)' and 'Questionnaire of Sasang Constitution Classification II(QSCCII)'. The following conclusion were made in comparison with Sasang Constitution and Questionnaire about disease and style of symptoms. 1. The subject of "increase of the weight of a body(gain weight), sweatier, the body swelled out, a lame pain, more like fat food, more like salty food", has significant differences in sasang constitution classification. The frequency of Taeeum group is more than that of Soeum group and Soyang group. 2. The subject of "the complextion is bas, uncomfortable feeling in the throat, insomnia, loss of appetite, apt to be fatigued easily, gastralgia what is not connected with food, diarrhea, headache, menorrhalgia, less like fat food, more like fresh food", has significant differences in sasang constitution classification. The frequency of Soeum group is more than that of Taeeum group and Soyang group. 3. It has not significant differences, but the frequency of Soyang group is more than that of Taeeum group and Soeum group in the subject of "the cough in the disease of the respiratory organs, hypomotility of the joint in the disease of the musculo-skeletal systems, menoxenia like menorrhagia and menostaxia and itching sensation of genitals in the disease of the gynecological organs, itching or boil in the dermatological disease", and fewer in the cardio-vascular disease, urinary disease and hematic disease. The frequency of Soeum group is more than that of Taeeum group and Soyang group in the subject of "the general disease of the digestive organs, uncomfortable feeling or pain of the throat in the disease of the respiratory organs, the general hematic disease, numbness or pain of the musculo-skeletal disease, psychical disease in the psychoneurotical disease, menorrhalgia, a lump of the breasts, leukorrhea in the gynecological disease, eruption or urticaria in the dermatological disease, the general visual and auditory disease". The frequency of Taeeum group is more than that of Soyang group and Soeum group in the subject of "a hoarseness in the disease of the respiratory organs, A lame pain of the musculo-skeletal disease, neurotical disease in the psychoneurotical disease, eruption or urticaria in the dermatological disease", and fewer in the the gynecological disease.

연접개발제한 폐지 이후 개발행위허가 심의제도 개선방안

김영우,윤정중,Kim, Young-Woo,Yoon, Jeong-Joong 한국토지주택공사 토지주택연구원 2012 LHI journal of land, housing, and urban affairs Vol.3 No.2

기반시설이 부족한 녹지지역 및 관리지역 농림지역 자연환경보전지역에서 난개발을 방지하고 환경을 보호하기 위하여 도입된 연접개발제한 제도는 이들 지역의 난개발 방지에는 기여하였지만 연접개발여부의 판단이 모호하고 소규모의 분산개발을 초래하거나 개발행위허가를 피해 산지전용허가를 통한 개발행위가 야기되는 등의 문제가 유발되어 폐지되기에 이르렀다. 그러나 난개발 방지를 위해 도시계획위원회의 심의를 받도록 하고 있으나 여전히 위원구성이나 재량권 남용 등의 문제를 안고 있으며, 녹지축 보전대책의 미흡, 공간정보체계의 활용 부족, 법률별 경관관리기준의 불일치, 그리고 물리적 환경규제의 획일화 등 여러 가지 문제들이 나타나고 있다. 따라서 심의제도 운영을 위한 개선방안으로, 도시계획위원회의 구성 및 기능재편과 전문분야 집중심의제 도입, 동일 녹지축 상의 지자체들의 경우 개발행위허가 통합조정위원회를 두어 녹지축 보전방안과 개발행위허가기준 마련, 도시계획정보시스템의 조기구축 및 활용, 개발행위허가 경관관리기준을 지역 실정에 맞게 세부적으로 구축, 개발행위허가 시 재량행위 최소화를 위해 경사도, 표고, 임목본수도 이외에 생태자연도와 국토환경성평가지도 등을 추가하여 개발행위허가 판단의 기초자료로 활용하는 방안 등을 제안하였다. The regulation of continuous and adjacent development was introduced to prevent unplanned and improper development and to protect environment in green zone and non-urban area that was deficient in infrastructure. Though it has been effective, it was repealed in 2011 by disorderly development problem caused by crafty tricks around restrictions. Alternatively, the Urban Planning Commission is now deliberating on the development permit, but there are still much to be resolved such as improper committee formation and abuse of power, insufficient green corridor preservation, a lack of use of planning information system, discordance between landscape management guidelines in laws, etc. Therefore, we suggest several ideas for improvement of development permit system as follows; intensive deliberation system in the Urban Planning Commission, integrated commission for green corridor prevention, early establishment of urban planning information system, making a development permission guideline to minimize discretional act of the Urban Planning Commission, etc.

페루의 석유가스 자원 개발 동향 및 제도 분석

김영우,박명호,이성훈,신홍자,Kim, Young-Woo,Park, Myong-Ho,Lee, Seong-Hun,Shin, Hong-Ja 대한자원환경지질학회 2008 자원환경지질 Vol.41 No.5

페루는 안데스산맥에 위치하는 태평양연안 국가로서 석유 자급이 불가능한 산유국임에도 불구하고 남미의 어느 국가에서도 찾아보기 힘든 좋은 투자 환경을 조성하여 외국 석유회사들의 투자를 유치하고 있다. 특히 외국 석유회사들이 페루 석유산업에 대거 투자할 수 있는 여건을 만들기 위하여 낮은 로열티, 세금 감면, 호의적 광권계약 조건 등과 같은 투자 환경을 만들었다. 유가의 급등으로 인하여 미개발 지역인 아마존 정글 지역의 1-AB광구나, 까미세아 가스전과 같은 성공적인 유전들이 불과 몇 년 사이에 개발, 생산되고 있으며, 우리나라 자원외교 전략과 부합되게 최근 여러 개의 페루 광구들에 대한 탐사, 개발, 생산에 우리나라의 석유회사들이 참여하게 되었다. 이 시기의 다른 남미국가들에 비하여 페루에 우리의 석유산업 투자가 보다 많아질 것으로 기대된다. Peru is located on Andean Range and faced Pacific Ocean and one of the important oil and gas production countries in the South America. Peru's oil business have been invested by foreign oil companies due to the good investment environment, even though the Peru could not be self-sufficiency in oil. Increase in oil price of the world has contributed to the oil and gas developments and productions in the last few years in many oil and gas blocks, such as in the 1-AB blocks and Camisea gas field within the Amazon jungles. Korean oil companies also have obtained several oil and gas blocks in the Peru in last few year, corresponding with the resources diplomacy of Korean government. Investment is strongly expected to be increased in the Peru's oil business due to positive investment environment, such as low royalty rate, tax avoidance, and the favourable terms of the contract to foreign companies etc.