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      • KCI등재

        현수(懸垂) 미생물 접촉체법의 미생물상에 관한 연구

        이수환,권숙표,정용,정재춘 한국물환경학회 1987 한국물환경학회지 Vol.3 No.2

        The Hanging Biological Contactor(HBC), which has been developed in 1984 and currently in experimental stage in Korea and Japan is a very new fixed-film process utilizing attached microorganisms on the polyvinylydene-chloride fiber media. It is similar to rotating biological contactor process but the media immersed in the wastewater does not rotate and appropriate air is supplied by the aeration apparatus underneath. Thes study was to identify HBC microorganisms and to determine their relative abundance. One pilot scale and two full scale Hanging Biological Contactors(HBC) were investigated for various microorganisms. Microorganisms found were pretty much similar to those fixedfilm reactors such as rotating biological contactors and trickling filters. In the start-up study of pilot scale HBC plant, Beggiatoa became highly populated in the first stage and the species diversity index increased along the stages with the time lapse. When the aeration level increased, the populations of Beggiatoa and Paramecium decreased, while those of Vorticella, Linonotus, Diplogaster(nematode), Philodina(Rotifer), and annelid Worms increased. Microorganisms also differ abundance by stages. More populations of Beggiatoa, Peranema, Amoeba, Paramecium, Trachelocerca, Aspidrsca, Linonotus, Oxytricha, Vorticella, Opercularia, Carchesium, Tokophrya, Philodina, and annelid Worms in the first 2 stages occured, while Arcella, Difflugia, Stylonychia, Trachelophyllum and Epistylis were shown higher abundance in the last stage (stage 3 and 4).

      • KCI등재

        일차 배양 랫드 혈관 평활근 세포에서 Prostaglandin 생성에 미치는 Bacterial Lipopolysaccharide 의 작용 특성

        이수환 한국식품위생안전성학회 1996 한국식품위생안전성학회지 Vol.11 No.4

        It is study was designed to characterize endotoxin-induced prostaglandin production in primary cultured rat vascular smooth muscle cells (VSMC). The time course for prostag)andim synthesis in lipopolysaccharide (LPS)-stimulated VSMC showed that the maximum production was reached in 12 hours. LPS induced prostaglandin H2 synthase (PGHS) activity in VSMC and the time course profile in the changes of PGHS activity paralleled that of total prostaglandin production. Differential treatment showed that 4 hours' exposure to LPS was enough for the maximum effect on the prostaglandin production and this effect was completely inhibited by the co-treatment of actinomycin D, a transcription inhibitor. These results suggest that LPS effect might be determined within 4 hours. Actinomycin D increased PGHS activity without affecting prostaglandin production if added 4 hours after LPS treatment. On the other hand, cycloheximide, a translation inhibitor, augmented LPS-induced prostaglandin production if treated during first four hours, but it inhibited LPS-induced PGHS activity regardless of treatment schedule. These results suggeat the existence of multiple regulating mechanisms in the LPS-induced prostaglandin synthesis.

      • KCI등재

        신종물에서 진단 및 병기결정을 위한 FDG-양전자방출단층 촬영의 임상적 역할

        이수환,조문기,이현무 대한비뇨의학회 2004 Investigative and Clinical Urology Vol.45 No.4

        Purpose: The role of [18F]fluorodeoxyglucose-positron emission tomography(FDG-PET) in renal cell carcinoma remains to be clearly defined. The sensitivity, specificity and accuracy of FDG-PET to detect renal cell carcinomas and a distant metastatic disease were compared with other established imaging modalities, including computerized tomography(CT), chest PA and bone scan. Materials and Methods: FDG-PET and conventional imaging techniques, including CT, chest PA and bone scan, were performed in 43 patients with primary renal tumors and/or metastatic diseases. Radical nephrectomy and metastatectomy were then performed. The results of FDG-PET were compared with the conventional imaging techniques and postoperative histopathological diagnoses. Results: The postoperative histopathological diagnoses of the 43 patients were renal cell carcinomas in 41 and benign renal tumors in 2. The results of FDG-PET were true positive, equivocal and false negative in 26, 8 and 9 of the 41 patients with renal cell carcinomas, respectively. The results of the CT were true positive in all patients. The results of FDG-PET were true negative in 2 patients, but those of CT were false positive in 2 patients with benign renal leiomyoma and angiomyolipoma. Therefore, FDG-PET was less sensitive, but more specific and accurate, than CT for the evaluation of primary renal tumors. CT was false positive for retroperitoneal lymph node metastasis and at the ascending colon in each of 1 patient, but FDG-PET was true negative. FDG-PET detected unsuspected pulmonary metastatic diseases that were not detected on chest PA in 4 patients. FDG-PET was more sensitive, specific and accurate than CT in the evaluation of metastasis. Conclusions: FDG-PET was complementary to conventional imaging in the initial staging of renal cell carcinomas, but superior in evaluating the metastasis. (Korean J Urol 2004;45:299-302)

      • 레이저스캐너를 활용한 철도건널목 안전성 향상 연구

        이수환,김유호,김건엽,백종현 한국통신학회 2015 정보와 통신 Vol.32 No.12

        본 글에서는 철도교통의 안전성 향상을 위해 철도건널목의 지장물을 검지하는 기술을 소개한다. 철도건널목에 자동차나 보행자 등 열차운행에 지장을 줄 수 있는 물체가 존재하는지 확인하기 위하여 현재 레이저빔 방식의 검지장치를 사용하고 있으나 기술적 한계와 문제점을 보이고 있다. 이를 극복하기 위해 2차원 레이저스캐너 센서를 적용하여 새로운 지장물 검지 시스템을 설계하였으며, 관심구간에 존재하는 물체의 크기와 방향 을 검지하는 알고리즘을 탑재하여 효과적인 지장물 인식이 가능하도록 하였다. 제작한 시작품을 실제 운영노선에 설치하여 현장시험을 수행하였다. 본 글에서는 개발된 기술을 설명하고 현장시험 결과를 소개하고자 한다.

      • KCI등재

        A Pilot Study of the Effectiveness of Medical Emergency System Implementation at a Single Center in Korea

        이수환,임아영,노영옥,김영아,김경덕,김영삼,김세규,정경수 대한중환자의학회 2017 Acute and Critical Care Vol.32 No.2

        Background: An automatic alarm system was developed was developed for unexpected vital sign instability in admitted patients to reduce staffing needs and costs related to rapid response teams. This was a pilot study of the automatic alarm system, the medical emergency system (MES), and the aim of this study was to determine the effectiveness of the MES before expanding this system to all departments. Methods: This retrospective, observational study compared the performance of patients admitted to the pulmonary department at a single center using patient data from three 3-month periods (before implementation of the MES, December 2013–February 2014; after implementation of the MES, December 2014–February 2015 and December 2015–February 2016). Results: A total of 571 patients were admitted to the pulmonary department during the three observation periods. During this pilot study, the MES automatically issued 568 alarms for 415 admitted patients. There was no significant difference in the rate of cardiopulmonary resuscitation (CPR) before and after application of the MES. The mortality rate also did not change. However, it appeared that CPR was prevented in four patients admitted from the general ward to the intensive care unit (ICU) during MES implementation. The median length of hospital stay and median length of ICU stay were not significantly different before and after MES implementation. Conclusions: Although we did not find a significant improvement in outcomes upon MES implementation, the CPR rate and mortality rate did not increase despite increased comorbidities. This was a small pilot study and, based on these results, we believe that the MES may have significant effects in longer-term and larger-scale studies.

      • KCI등재

        조선전기 선비들이 추구한 유교적 이상사회

        이수환 경북대학교 퇴계연구소 2015 퇴계학과 유교문화 Vol.56 No.-

        The topic of this study is seonbi during early Chosun and is going to look into Confucian ideal society that they pursued then. The seonbi in Chosun generally refers to the sadaebu during late Goryeo and early Chosun. Concerning the foundation of Chosun Dynasty, they were divided into Gwanhakpa and Sahakpa, and then, after the Sejojeongbyeon, they were separated into Hungupa and Sarimpa. The aspects of seonbi, the topic of this paper, are more distinctly found in Sarimpa as the force criticizing the hungu force that ruled in the 16th century. In this period, the sarim force exhibited several characteristics differently from the ruling power. The key points are that (1) they pursued Dohak politics to found a politically Confucian ideal state, and this was genuinely started from Jo Gwangjo. (2) In the point that the academic activities were done on the residing ground of hyangchon, they were strongly characterized by the color of hangdang(鄕黨). Their major concern over the matters of hyangchon was to reorganize the previous Goryeo’s ijok(吏族)-centered hyangchon society that was based on Buddhism and eumsa(淫祀) into the Confucian system of hyangchon order centered around sajok(士族). For this, they developed the Yuhangso Restoration Movement and also Hyangyak·Seowon Distribution Movement in order to spread practical, new-Confucian ethics including 『Jujagarye (朱子家禮)』, 『Sohak(小學)』, Hyangsarye(鄕射禮), or Hyangeumjurye(鄕飮酒禮). (3) They transmitted and practiced the notion of Jeolui(節義) as the pretext of new-Confucianism. (4) They also promoted the Munmyojongsa Movement to solidify their academic legitimacy to justify their reign. This study has arranged the aspects of the sarim force in that period with the four characteristics above. 본고는 조선전기 선비라는 주제로 그들이 추구한 유교적 이상사회에 대해 검토하였다. 일반적으로 조선시대 선비라고 하면 여말선초의 사대부라 할 수 있는데, 이들은 조선왕조 개국을 둘러싸고 관학파와 사학파로 이후 세조정변을 계기로 훈구파와 사림파로 나누어지게 되는데, 본고의 주제인 선비의 모습은 16세기 집권 훈구세력에 대한 비판세력으로서의 사림파에서 더 선명하게 나타난다. 이 시기 사림세력은 집권세력과 다른 몇 가지 특징이 있는데, 그 핵심은 (1) 정치적으로는 유교적인 이상국가 건설을 위한 도학정치를 추구하였으며, 이것이 본격적으로 제기된 것은 조광조부터이다. (2) 향촌의 재지적 기반 위에서 학문활동이 이루어졌다는 점에서 鄕黨的 색채를 강하게 띠고 있다. 이들의 향촌문제에 대한 관심은, 종래의 고려조적인 佛敎的이고 淫祀的인 吏族중심의 향촌사회를 士族 중심의 유교적인 향촌질서체제로 재편하고자 하였다. 이를 위해 『朱子家禮』․『小學』․鄕射禮․鄕飮酒禮 등 성리학적 실천윤리의 보급을 위한 유향소 복립운동, 나아가 향약·서원보급 운동을 전개하였다. (3) 성리학적 대의명분으로 節義사상을 계승 실천하였고 (4) 집권의 명분 강화를 위한 학문적 정통성 강화를 위한 문묘종사 운동을 추진하였다. 본 논문에서는 이러한 이 시기 사림세력을 특징지울 수 있는 위 4가지를 중심으로 정리한 것이다.

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