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이남준,정환훈,설혜영,김정혁,정용구,이훈갑 고려대학교 의과대학 1997 고려대 의대 잡지 Vol.34 No.2
Pituitary adenoma is usually confined in the sella or extends superiorly beyond the diaphragm sella. There are some cases that invade the adjacent perisellar structures, and then it is difficult to differentiate it from other juxtasellar tumors. The purpose of this study is to evaluate MR findings of the invasive pituitary adenoma. We evaluated the MR findings of 10 pathologically proven pituitary adenoma which invaded the cavernous sinuses. There were 4 males and 6 females. Average age was 41.5 years. Observation was made of the MR signal intensity, average size, degree and direction of tumor invasion, associated hydrocephalus, cystic or hemorrhagic changes in the tumor, and characteristic findings according to the secreting hormones. Average tumor size was 4.1 × 3.8 × 4.1 cm. Of the 10 tumors, 9 tumors extend superiorly, 5 tumors inferiorly, and 2 tumors posteriorly. 4 tumors had internal cystic changes, and 1 of these 4 tumors had combined hemorrhage. 6 tumors had no internal degeneration in the mass. Tumor signal intensities were similar to brain cortex on T1WI and T2WI, and all masses enhanced intensely. Prolactin secreting tumor frequently extended inferiorly (3/4), and nonsecreting tumor did not have internal degeneration(0/4). In conclusion, invasive pituitary adenoma was frequently noted as homogenous solid mass, especially nonsecreting tumor. There were some characteristic findings in internal degeneration and direction of invasion according to secreting hormons. Mode of tumor invasion would be helpful to differentiate pituitary adenoma from other juxtasellar tumors.