젊은이 발언대 -축산업계에 대한 나의 바람

최석호 대한양계협회 1980 월간 양계 Vol.12 No.4

젊은이들의 날카롭고 신선한 눈으로 보는 업계와 그 문제점은 어떠한가? 본지에서는 4월호부터 '젊은이의 발언대'난을 신설하여 젊은이들의 많은 참여를 바라고 있다. 이번호는 그 첫벗째로서 최석호군의 눈에 비친 업계와 그 비젼을 들어본다.

Characterization of Fibrinolytic Proteases from Gloydius blomhoffii siniticus Venom

최석호 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.3

Objectives : This study was undertaken to identify fibrinolytic proteases from Gloydius blomhoffii siniticus venom and to characterize a major fibrinolytic protease purified from the venom. Methods : The venom was subjected to chromatography using columns of Q-Sepharose and Sephadex G-75. The molecular weights of fibrinolytic proteases showing fibrinolytic zone in fibrin plate assay were determined in SDS-PAGE (Sodium dodecyl sulfate-polyacrylamide gel electrophoresis)The effects of inhibitors and metal ions on fibrinolytic protease and the proteolysis patterns of fibrinogen,gelatin, and bovine serum albumin were investigated. Results :1) The fibrinolytic fractions of the three peaks isolated from Gloydius blomhoffii siniticus venom contained two polypeptides of 46 and 59 kDa and three polypeptides of 32, 18, and 15 kDa and a major polypeptide of 54 kDa, respectively. 2) The fibrinolytic activity of the purified protease of 54 kDA was inhibited by metal chelators, such as EDTA, EGTA, and 1,10-phenanthroline, and disulfhydryl-reducing compounds, such as dithiothreitol and cysteine. 3) Calcium chloride promoted the fibrinolytic activity of the protease, but mercuric chloride and cobalt(II) chloride inhibited it. 4) The fibrinolytic protease cleaved preferentially Aα-chain and slowly Bβ-chain of fibrinogen. It also hydrolyzed gelatin but not bovine serum albumin. Conclusions : The Gloydius blomhoffii siniticus venom contained more than three fibrinolytic proteases. The major fibrinolytic protease was a metalloprotease which hydrolyzed both fibrinogen and gelatin, but not bovine serum albumin.

부록 / 매일 말씀듣기 : 말씀의 빛 성결한 삶 ; 고린도후서 , 갈라디아서 ( 활천사 , 활천 통권 제 519 호 , 1997 . 2 )

최석호,천병호 기독교대한성결교회 활천사 1997 활천 Vol.519 No.-

Isolation from Gloydius blomhoffii siniticus Venom of a Fibrin(ogen)olytic Enzyme Consisting of Two Heterogenous Polypeptides

최석호,이승배 대한약침학회 2013 Journal of pharmacopuncture Vol.16 No.2

Objective: This study was undertaken to isolate a fibrin(ogen)olytic enzyme from the snake venom of Gloydius blomhoffii siniticus and to investigate the enzymatic characteristics and hemorrhagic activity of the isolated enzyme as a potential pharmacopuncture agent. Methods: The fibrinolytic enzyme was isolated by using chromatography, sodium dodecyl sulfatepolyacrylamide gel electrophoresis, and fibrin plate assay. The characteristics of the enzyme were determined by using fibrin plate assay, protein hydrolysis analysis, and hemorrhage assay. Its amino acid composition was determined. Results: The fibrin(ogen)olytic enzyme with the molecular weight of 27 kDa (FE-27kDa) isolated from G. b. siniticus venom consisted of two heterogenous disulfide bond-linked polypeptides with the molecular weights of 15 kDa and 18 kDa. When more than 20 μg of FE-27kDa was applied on the fibrin plate, fibrinolysis zone was formed a indicating its fibrinolytic activity. The fibrinolytic activity was inhibited completely by phenylmethanesulfonylfluoride (PMSF) and ethylenediaminetetraacetic acid (EDTA) and partially by thiothreitol and cysteine. Metal ions such as Hg2+ and Fe2+ inhibited the fibrinolytic activity completely, but Mn2+ did not. FE-27kDa preferentially hydrolyzed α-chain of fibrinogen and slowly hydrolyzed β-chain, but did not hydrolyze γ-chain. High-molecular-weight polypeptides of gelatin were hydrolyzed partially into polypeptides with molecular weights of more than 45 kDa. A dosage of more than 10 μg of FE-27kDa per mouse was required to induce hemorrhage beneath the skin. Conclusion: FE-27kDa was a serine proteinase consisting of two heterogeneous polypeptides,hydrolyzed fibrin, fibrinogen, and gelatin, and caused hemorrhage beneath the skin of mouse. This study suggests that the potential of FE-27kDa as pharmacopuncture agent should be limited due to low fibrinolytic activity and a possible side effect of hemorrhage.

2 . 젖산균 성장용 질소화합물 급원배지의 개선에 관한 연구

최석호,김현욱 한국축산학회 1979 한국축산학회지 Vol.21 No.3

Giddens 의 근대성 이론으로 분석한 한국의 관광자원 개발 과정: 근대관광의 세계화와 한국의 관광자원개발에 대한 논의

최석호 한국관광학회 2004 관광학연구 Vol.28 No.1

관광의 세계화: 유산관광개발 한영 비교사례연구

최석호 한국관광학회 2006 관광학연구 Vol.30 No.3

Globalisation as the result of modernity has expanded the boundary of tourism over national limit, diversified and dedifferentiated tourism. Consequently, tourism destinations and experiences sought by today’s sophisticated tourists have been diversified. Therefore, the tourist destinations worldwide face with various kinds of threat. In other words, the globalisation of tourism has resulted in intense competition among destinations all over the world. One of the responses to these phenomena is developing heritage tourism. In this study, two cases of heritage tourism development, sharing similarities, as once a booming industrial city but declined, in Korea and in England were analyzed to compare the development process and consequent results. The Korean of heritage tourism case was developed from democratisation and the British case of heritage tourism development was from industrialisation. It was, however, concluded that the success or failure of the heritage tourism development in both countries’ cases is unpredictable considering the diverse circumstantial factors.

관광패러다임 전환과 제 3의 길로서 네오투어리즘

최석호,김남조,최승담,김봉중 한국관광학회 2008 관광학연구 Vol.32 No.1

As conditions of modernity are transforming from modern society to higher one, tourism paradigm also is now being under shift from old to new one. Bearing problems in old tourism, another problems are emerging even in new tourism. Without new paradigm it is unlikely to overcome the new problems produced by new tourism. NeoTourism articulates the problems and tries to find the third way in tourism. In contrast to reductionism of prior endeavour against the problems, Neo-Tourism articulates its meanings along each of the institutional dimensions of the globalising modernity. Authors also discuss wider implications of this new trends, Neo-Tourism.

책읽기와 출판산업을 통해 본 여가의 세계화

최석호,옥성삼 여가문화학회 2011 여가학연구 Vol.9 No.1

Huge social changes have been introduced by globalisation during last 20 years in Korea. Book reading as a leisure activity, book as a leisure product, and publishing as a leisure industry should do take the influences and exert influences on neoliberal globalisation without exception. Content analysis, in-depth interview, and literary study have been used for explaining and analysing the take and exert. Book reading was a battle field of politics of the national identity. Also there were firm concentration, polarisation and digitalisation in the industry. At the very first stage of globalising of book reading resulted in best hit of books on self improvements and making money. However, as time goes to the next stage, it has been changed to rage and despair. Aspects of best selling books also have changed. Books on questioning justice for whom deprived of and consolation to whom it may needed in a globalising era are enjoying a large fortune in publishing market. It is not a passing phase but a stage setting phase of best selling books in Korean publishing market. As a result, globalisation of social context is structuring leisure activity and leisure practitioner responding politics of national identity try to take autonomy in the process of structuration. 최근 약 20년 동안 진행된 세계화는 우리 사회에 큰 변동을 초래하였다. 그 과정에서 여가활동과 여가생산물에도 변화가 발생했다. 본 논문은 책읽기와 출판산업을 사례로 세계화 과정에서 발생한 여가의 변동을 규명하고자 했다. 이와 같은 연구목적을 달성하기 위해서 베스트셀러에 대한 내용분석, 출판종사자에 대한 심층면접, 각종 2차 자료를 바탕으로 한 문헌연구 등의 방법을 사용하였다. 베스트셀러를 통해서 여가실행의 세계화가 여가활동으로서 책읽기를 민족정체성 정치의 장이 되게 하였으며, 여가산업으로서 출판산업을 양극화와 디지털화의 경연장이 되게 했다. 신자유주의적 세계화 상황이 초래한 무한경쟁에서 살아남기 위한 노력은 베스트셀러에서도 고스란히 드러나, 자기계발서와 경제경영서가 책 읽는 사람들의 사랑을 받았다. 그러나 양극화로 말미암아 중산층은 몰락하고 몰락한 중산층의 상승이동은 차단당하면서 좌절은 포기를 초래했다. 세계화 초기에는 적응하고자 하는 시도가 주를 이루면서 자기계발서의 베스트셀러화가 나타났으나, 후기로 가면서 양극화로 인한 분노와 좌절이 극명하게 드러났다. 좌절과 분노의 강도만큼 베스트셀러의 양상도 정의에 대한 의문제기와 시대로부터 기회를 상실당한 세대에 대한 정당한 위로로 바뀌어 갔다. 결론적으로, 사회적 맥락으로서 세계화는 여가활동을 구조화시키고 여가활동 참가자는 이 구조화 과정 속에서 민족정체성으로 대응하면서 자율성을 추구한다.

세계화와 여가의 사회적 의미 2002 한?일 월드컵을 중심으로

최석호 한국관광학회 2003 관광학연구 Vol.26 No.4

Without understanding globalization process, it seems not possible to understand local or national context of experiences. The globalized of sport has impact on the embodied national identities, which again is menifested in local and national cultural processes. The game style and supporting culture seemed completely different from standardization and homogenization. What we call, Korean-styled power soccer had been created by the Korean national football squad and the sporting event had been changed into the representational space of national identities. What had been observed is that the sport as a leisure practice in globalization and national identity formation plays contradictory role, diminishing contrasts and increasing varieties.