High levels of carcinoembryonic antigen and smoking might be markers of colorectal adenoma in Korean males aged 40-49 years

윤인철,이홍섭,조정현,최영훈,임규민,최성화,한재호,정현주 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.1

Background: Prevalence of adenoma in males aged 40-49 years in Korea was higher than expected. The aim of this study was to investigate the prevalence and risk factors of colorectal adenoma in males aged 40-49 years. Methods: Total 1,902 asymptomatic subjects with a mean age of 47.9±6.7 years, who underwent a screening colonoscopy in a health promotion center of Myongji Hospital from 2010 to 2013 were enrolled in this study. We conducted a case-control study to determine the risk factors for adenoma. The subjects were classified into two groups (adenoma vs. controls). To validate the diagnostic value of carcinoembryonic antigen (CEA) for adenoma, area under the receiver operating characteristic curve (AUROC) was calculated. Results: At least one colorectal adenoma was identified in 385 subjects (20.2%). Among these 385 subjects, 372 subjects were found to have a non-advanced adenoma, 13 subjects had an invasive adenoma. One subject had cancer. Male sex, age, smoking, metabolic syndrome, and elevated CEA level were significantly associated with a colorectal adenoma in univariate analysis. However, metabolic syndrome was not significant in multivariate analysis. In the male group, the AUROC of CEA for colorectal adenoma was 0.600 (0.543 to 0.656) in non-smokers under 50 years of age, and 0.615 (0.540 to 0.690) in smokers under 50 years of age. Conclusion: Male sex, smoking, and high levels of CEA seem to be associated with colorectal adenoma. High levels of CEA and smoking may be diagnostic markers for any colorectal adenoma in Korean males aged 40-49 years. Background: Prevalence of adenoma in males aged 40-49 years in Korea was higher than expected. The aim of this study was to investigate the prevalence and risk factors of colorectal adenoma in males aged 40-49 years. Methods: Total 1,902 asymptomatic subjects with a mean age of 47.9±6.7 years, who underwent a screening colonoscopy in a health promotion center of Myongji Hospital from 2010 to 2013 were enrolled in this study. We conducted a case-control study to determine the risk factors for adenoma. The subjects were classified into two groups (adenoma vs. controls). To validate the diagnostic value of carcinoembryonic antigen (CEA) for adenoma, area under the receiver operating characteristic curve (AUROC) was calculated. Results: At least one colorectal adenoma was identified in 385 subjects (20.2%). Among these 385 subjects, 372 subjects were found to have a non-advanced adenoma, 13 subjects had an invasive adenoma. One subject had cancer. Male sex, age, smoking, metabolic syndrome, and elevated CEA level were significantly associated with a colorectal adenoma in univariate analysis. However, metabolic syndrome was not significant in multivariate analysis. In the male group, the AUROC of CEA for colorectal adenoma was 0.600 (0.543 to 0.656) in non-smokers under 50 years of age, and 0.615 (0.540 to 0.690) in smokers under 50 years of age. Conclusion: Male sex, smoking, and high levels of CEA seem to be associated with colorectal adenoma. High levels of CEA and smoking may be diagnostic markers for any colorectal adenoma in Korean males aged 40-49 years.

프랜차이즈 지원서비스가 가맹점 경영성과 및 만족도에 미치는 영향

윤인철 한국경영교육학회 2011 경영교육연구 Vol.26 No.3

The common practice of supports provided to the franchisee by the franchiser is mostly focused on such activities as menu development, provision of interior concept and goods supplies while giving less emphasis on detailed operational guidance. It is important that a structured operational system is established to pursue successful long-term franchise business objectives. Accordingly the purpose of this thesis is to in and out key factors for the successful franchise business through the study of franchise food service industry by finding out the differences among franchisees resulting from supports level, business performance and franchisee satisfaction and by analyzing the impacts of performance and satisfaction by the supports from the franchiser. To achieve the objective of this study pre-studies of related areas including supervisor, marketing support, menu development, business performance and satisfaction were examined and actual verification analysis was implemented. Through the actual analysis process reliabilities of each concepts were verified and a regression analysis was adopted for the assumption verification. As a result the key findings are as follows: Firstly, an attempt was made to see any difference among franchisee characteristics due to supports by the franchiser. This revealed that meaningful result was found supervisor support vis-a-vis shop floor size while there was little meaning regarding business performance and satisfaction level. Secondly, an attempt was made to find out impacts of franchiser's supports on business performance. This test revealed that there are statistically positive meanings in all areas including supervisor supports, marketing support and menu developments. Thirdly regarding the impacts of supporting services by the franchisers to the franchisees satisfaction it was found out that there were statistically positive meanings in all area including supervisor supports, marketing supports and menu development. Accordingly the implication of this study can be summarized as below:Firstly, supervisors' support by the franchisor is needed who can increase the effectiveness of the shop through systematic management and operational service by managing the problems and fixing the flaws in business management. To this end the franchisor needs to recruit and train the experienced and professional supervisors and establish compensation and incentive systems to keep the motivation of the supervisors. Secondly the franchisees will have to be classified considering external factors such as competition. traffic condition, changes in target customer and internal factors such as changes in related parties and employees, price changes, promotional activities and CRM etc. Based on this classification responding strategy can be implemented. By exploring the changing customer needs the franchisor should use mass media as newspaper, broadcast and on-line media. Thirdly, menu development which is considered to be one of the most important factors or the performance and satisfaction is the key to managing and controlling the food service business. The franchisor should develop menu by reflecting food item, market conditions of raw materials, cooking methods, service way, selling price, changing trend, consumption trend and seasonal considerations through analysis of selling price per customer, customer level and competitions. Also the purpose of menu development should be clarified if the purpose sevres frequency of the visits, increase of new customers, growth of sales, reduction of production et. The realization of sustained profit of franchisee is the most important key to the success of the business and the more support on the part of franchisor increases the probability franchisee success. It is important to understand that the success of franchiser is defendant on the success of franchisee and therefore the franchiser should try to obtain the win-win results between the two parties by managing th... 본 연구는 외식프랜차이즈 본부의 지원서비스가 가맹점의 경영성과와 만족도에 어떠한 영향을 미치는가를 분석하여 외식프랜차이즈 본부의 성공적인 사업운영 및 프랜차이즈산업 발전에 중요한 시사점을 제공하는 것이 목적이다. 가설을 검증한 결과는 첫째, 가맹본부의 지원서비스에 대해서 가맹점특성에 따라 차이가 있는지에 대해서는 슈퍼바이저 운영에만 점포의 총 면적에 따라서 유의한 차이가 나타났으며, 경영성과와 만족도에 대해서는 의미 있는 관련성이 적은 것으로 나타났다. 둘째, 지원서비스가 경영성과에 미치는 영향에 대해서는 슈퍼바이저운영, 마케팅지원, 신 메뉴개발 모두 경영성과에 통계적으로 유의한 정(+)의 영향을 미치는 것으로 파악되었다. 셋째, 가맹본부의 지원서비스가 가맹점만족에 미치는 영향에 대해서는 슈퍼바이저운영, 마케팅지원, 신 메뉴개발 모두 가맹점만족에 통계적으로 유의한 정(+)의 영향을 미치는 것으로 파악되었다. 따라서 가맹점 매출증대를 위한 체계적인 매장관리 및 운영지원, 문제점 체크, 보완사항 등을 접수하여 수시로 반영하고, 철저한 매뉴얼 관리를 통해 매장효율성 증대를 지원할 수 있는 슈퍼바이저시스템이 필요하다. 또한 변화하는 경영환경과 고객의 니즈와 욕구를 파악하여 시장점유율과 잠재고객을 확보하여 가맹점 매출증대에 노력해야 하며, 브랜드이미지 확대를 위해 신문, 방송, 라디오, 온라인 등 대중매체를 이용한 홍보나 광고를 통해 직․간접적으로 가맹점에 도움이 될 수 있도록 본사는 지속적이고 차별화된 다양한 마케팅활동을 지원해야 한다. 또한 가맹본부는 객 단가, 고객 층, 경쟁점포 등 사전분석을 통해 고객에게 제공할 아이템, 식자재의 시장조건, 조리방식, 서비스방식, 판매가격, 변화하는 트렌드, 소비동향과 기호, 계절적인 요인 등을 고려한 메뉴개발을 통해 가맹점의 지속적인 영업활동과 수익 창출에 기여할 수 있도록 지원해야 한다. 가맹점들의 지속적인 이익실현은 프랜차이즈 사업의 최대 관건이며, 가맹점에 대한 계속적인 지원정도가 많을수록 가맹점의 성공가능성은 높아진다.

탐지 레이다용 헬릭스 진행파관 증폭기 지연파구조 특성 연구

윤인철,김희식 대한전기학회 2008 정보 및 제어 심포지엄 논문집 Vol.2008 No.1

본 논문에서는 탐지레이다용 진행파관증폭기 (TWTA: Traveling Wave Tube Amplifier)의 개발을 위한 지연파 구조 특성을 제안한다. 지연파구조 특성 및 이론적 해석을 위해 증폭기 설계 및 구현시 HFSS Code와 LMSuite Code를 활용 하였다. 나선형 저속파 진행파관 증폭기의 절단 및 시뮬레이션을 통하여 제안한 측정값이 설계규격을 만족시키는 결과를 얻었다. 본 논문에서 제안한 규격은 매우 유용하며 따라서 차후 유사장비 개발시 적용 가능할 것으로 판단된다. This paper suggests an applicable study on Helix TWT of Slow-Wave Structure for Surveillance RADAR. In order to improve Slow-Wave Structure performance and analysis, we design and realizer a Helix TWTA using a HFSS Code and LMSuite Code, Through the cutting and simulation of Helix TWTA, this parameter satisfies the design specifications, Therefore, this specifics is very useful and can be used to develop the similar equipments

대학생의 개인적 특성이 창업멘토링과 교육만족, 창업의지에 미치는 영향

윤인철 한국융합학회 2017 한국융합학회논문지 Vol.8 No.6

본 연구는 대학생의 개인특성에 따라 창업멘토링과 창업교육만족도, 창업의지에 미치는지 영향에 관한 연구를 알아보고, 대학생의 창업역량과 창업성과를 높이기 위한 방법을 도출하는 것이 주요한 목적이다. 이를 위해 광주지역 대학생 237명의 표본자료 통계처리는 SPSS 2.0 For Windows를 활용하여 빈도분석, 신뢰도분석, 요인분석, 다중회귀분석 실시하였다. 혁신성을 제외한 개인적 특성요인은 창업멘토링, 창업교육만족도에 영향을 미치고, 창업멘토링은 창업교육만족도에 영향을 미치는 것으로 나타났으며, 창업멘토링요인 중 역할모델기능만이 창업의지에 영향을 미치는 것으로 나타났고. 창업교육만족은 창업의지에 영향을 미치는 것으로 나타났다. 결과적으로 대학에서는 역량 있는 창업멘토를 선정하고, 대학생의 개인적 특성에 맞는 창업멘토링과 체계적인 창업교육 프로그램을 통해 창업의지와 창업성과를 높일 수 있다. This research is conducted a study on the effect of startup mentoring and education satisfaction as well as startup intention on the individual characteristics of university students, therefore, to draw way to increase start up ability of university student as well as their outcome is a primary purpose. Statistics process of sample data for 237 students at the local university in Gwangju is performed an analysis of frequency, reliability, factor, and multiple regression utilized SPSS 2.0 For windows. Individual characteristics except for innovativeness have effected on startup mentoring as well as startup education satisfaction while start up mentoring has effected on start up intention. Only role model function among start up mentoring factors has effected on start up intention while startup education satisfaction has effected on start up intention. As a result, start up intention and its outcome in university will be increased through not only selection of start up mentors with a competence and a passion but also start up mentoring and systematic start up education program fit for individual personality of university student.

생활 스포츠 참여자의 재미요인이 기본심리욕구 및 자기관리에 미치는 영향

윤인철,장덕진 대한체육학회 2023 대한스포츠융합학회지 (jcses) Vol.21 No.3

The purpose of this study is to analyze and investigate how the fun factors of participants in sports affect basic psychological needs and self-management. In order to achieve the purpose of this study, the general public participating in daily sports in the domestic metropolitan area was selected, and 311 participants were conveniently sampled as domestic daily sports participants. The results of data processing using frequency analysis, exploratory factor analysis, reliability analysis, t-test, one-way variance analysis, correlation analysis, and multiple regression analysis using the SPSS Version 25.0 program are as follows. First, there was a partially significant difference in fun factors, basic psychological needs, and self-management according to the demographic characteristics of sports participants. Second, it was found that the fun factors of participants in sports for all had a significant effect on basic psychological needs. Third, it was found that the fun factors of participants in sports for all had a significant effect on self-management. Fourth, it was found that the basic psychological needs of sports participants had a significant effect on self-management. Taken together, these results showed that the fun factors of participants in sports for all had a significant effect on basic psychological needs and self-management.

Pharmacologic therapy for nonalcoholic steatohepatitis focusing on pathophysiology

윤인철,은종렬 영남대학교 의과대학 2019 Yeungnam University Journal of Medicine Vol.36 No.2

The paradigm of chronic liver diseases has been shifting. Although hepatitis B and C viral infections are still the main causes of liver cirrhosis and hepatocellular carcinoma (HCC), the introduction of effective antiviral drugs may control or cure them in the near future. In contrast, the burden of nonalcoholic fatty liver disease (NAFLD) has been increasing for decades, and 25 to 30% of the general population in Korea is estimated to have NAFLD. Over 10% of NAFLD patients may have nonalcoholic steatohepatitis (NASH), a severe form of NAFLD. NASH can progress to cirrhosis and HCC. NASH is currently the second leading cause to be placed on the liver transplantation list in the United States. NAFLD is associated with obesity, type 2 diabetes, dyslipidemia, and metabolic syndrome. The pathophysiology is complex and associated with lipotoxicity, inflammatory cytokines, apoptosis, and insulin resistance. The only proven effective treatment is weight reduction by diet and exercise. However, this may not be effective for advanced fibrosis or cirrhosis. Therefore, effective drugs are urgently needed for treating these conditions. Unfortunately, no drugs have been approved for the treatment of NASH. Many pharmaceutical companies are trying to develop new drugs for the treatment of NASH. Some of them are in phase 2 or 3 clinical trials. Here, pharmacologic therapies in clinical trials, as well as the basic principles of drug therapy, will be reviewed, focusing on pathophysiology.

X대역 광대역 진행파관용 구동증폭기 펄스 SSA 설계 및 성능분석

윤인철(Inchul Yoon),김희식(Hiesik Kim) 제어로봇시스템학회 2011 제어로봇시스템학회 합동학술대회 논문집 Vol.1 No.2

본 논문에서는 X대역 광대역 진행파관증폭기 TWT(Travelling Wave Tube)의 구동증폭기 SSA를 제작하기 위하여 CSSDA 방법을 이용하여 2단의 전력증폭기를 설계, 제작하였다. RF(Radio Frequency) 특성 및 이득 향상을 위해 사용된 구동증폭기 SSA(Solid State Amplifier)설계 및 신뢰도 문제를 해석하고 8KW급 X대역 진행파관 증폭기 구현 및 시험을 통하여 제안한 방안이 설계규격을 만족시키는 결과를 얻었다. 따라서 본 논문에서 제안한 방안은 매우 유용하며, 차후 광대역 Microwave Power Module (MPM) 및 진행파관 구동증폭기 개발 시 적용가능 할 것으로 판단된다.

대학생 창업의 심리적 특성이 창업교육만족도를 통해 창업의도에 미치는 영향

윤인철 ( Incheal Yoon ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.6

본 연구의 목적은 대학생 창업의 심리적 특성이 창업교육만족도를 통해 창업의도에 어떠한 영향을 미치는지 인과관계를 실증적으로 검증하고자 한다. 본 연구를 실증적으로 검증하기 위해 대학생을 선택하여 설문조사를 실행하였다. 설문조사를 통해 250명의 표본을 수집하였으며, 불성실한 표본을 제거한 후 240명의 표본을 대상으로 요인들 간의 관계를 분석하기 위해 경로를 분석하였다. 경로분석결과 성취욕구와 위험감수성은 창업교육만족도에 유의한 영향을 미치지 않는 것으로 나타났고, 통제위치와 모호성인내력은 창업교육만족도에 유의한 영향을 미치는 것으로 나타났다. 그리고 창업교육만족도는 창업의도에 유의한 영향을 미치는 것으로 나타났다. 결국 대학 내에서 창업에 대한 다양한 정보교환과 새로운 기회를 발견하고 도전할 수 있는 차별화된 대학의 창업문화 조성이 필요하다. 추후 연구에서는 창업의지에 미치는 다양한 계층의 표본을 확보하여 연구를 진행하고 자기결정성 심리욕구동기가 창업의지에 미치는 요인에 관한 연구가 필요하다. The purpose of this study is to empirically verify the causal relationship that the psychological characteristics of university students’ entrepreneurship affect entrepreneurial intention through entrepreneurship education satisfaction. To empirically verify this study, a survey was conducted with college students. A sample of 250 people was collected through a survey, and the path was analyzed to analyze the relationship between factors in a sample of 240 people after removing the unfaithful sample. As a result of path analysis, it was found that achievement desire and risk tolerance did not have a significant effect on entrepreneurship education satisfaction, and control position and ambiguity tolerance showed significant influence on entrepreneurship education satisfaction. In addition, it was found that the satisfaction of entrepreneurship education had a significant effect on the intention to start a business. In the end, it is necessary to create a differentiated university entrepreneurship culture that can exchange various information about entrepreneurship and discover and challenge new opportunities within the university. In future research, it is necessary to secure a sample of various classes that affect entrepreneurial intentions and conduct research on the factors that self-determination psychological drive motives have on entrepreneurial intentions.

저고도 탐지레이다용 고속 저잡음 주파수합성기 개발에 관한연구

윤인철(Inchul Yoon),김희식(Hiesik Kim) 대한전기학회 2009 정보 및 제어 심포지엄 논문집 Vol.2009 No.5

본 논문에서는 저고도 탐지레이다 센서체계의 주파수 협성기는 송수신 장치의 기준 주파수원으로 이용될 국부 발진 주파수들을 생성해 내는 주파수 합성부에 대해 설명되었다. 주파수 합성기의 성능을 평가하기위하여 각 주파수 원들의 위상잡음 특성과 주파수 합성기의 스위칭 시간을 신호 혼합기를 이용하여 측정 하였으며, 그 결과 설계 시 제시한 30(usec)이하인 약18usec의 스위칭 시간이 대부분을 차지함을 알 수 있었다. 주파수 합성기에서 생성된 최종 출력 주파수는 저고도 닦지 레이다의 송수신 장치의 국부발진 주파수로 이용되므로 출력 레벨의 flatness를 측정하여 분석한다.

마이크로파 탐색레이더 진행파관증폭기 정비시스템 구현

윤인철(In-Chul Yoon),권종원(Jongwon Kwon),박용만(Yongman Park),오드게럴(Odgerel),김희식(Hiesik Kim) 대한전기학회 2006 정보 및 제어 심포지엄 논문집 Vol.2006 No.1

This traveling wave tube amplifier maintenance system was developed for performance of microwave Surveillance radar traveling wave tube amplification parts, and field operation. The Maintenance system is traveling wave tube amplification part RF output waveform measurement and HVPS Voltage adjustment and a maintenance function are offer. The system was developed as an embedded system base it consisted of Linux os which applied a top-down design and visual technique Therefore change and easy extension of a system. This paper discussed characteristic of maintenance equipment function, composition, and an emplovment program.