건강한 성인을 대상으로 면역증강 및 상기도 감염 예방에 대한 동충하초주정추출물의 유효성 평가 : 이중맹검 플라세보 대조 연구

정수진(Su Jin Jung),황지현(Ji Hyun Hwang),오미라(Mi Ra Oh),채수완(Soo Wan Chae) 한국영양학회 2019 Journal of Nutrition and Health Vol.52 No.3

본 연구는 한국인 건강한 성인에게서 12주간 동충하초 주정추출물의 섭취가 면역기능 증진 및 상기도감염 예방효과에 대해 확인하였다. 면역관련 지표인 NK-cell activity는 시험식품 섭취군이 플라세보군에 비해 유의적으로 증가하여 (p = 0.047) 면역증강 효과에 대해 확인하였다. 또한, 점막 면역에 주요 역할을 하는 항체 IgA 변화량은 시험식품 섭취군에서 플라세보군에 비해 통계적으로 유의하게 증가하였다 (p = 0.035). 본 연구대상자의 상기도감염(URI) 발생률은 시험식품 섭취군과 플라세보군, 두 군 간 유의한 차이는 관찰할 수 없었다. 안전성 평가인 진단검사 의학 검사와 활력진후 결과에서도 섭취군 내 및 섭취군 간 의미 있는 변화 또는 차이는 관찰되지 않았다. 본 연구에서 동충하초주정추출물의 섭취가 URI 발생률에 대한 유의한 변화는 관찰할 수는 없었으나 면역지표인 NK-cell 활성 증가와 혈청 IgA 농도 증가를 통해 선천성 면역과 후천성 면역을 증진시키는 작용이 있어, 잠재적인 상기도감염 예방 효과에 관련성 있을 것으로 사료되며, 항생제의 약물 의존도를 낮추며 삶의 질 개선 및 국민보건 향상에 기여할 것으로 사료된다. Purpose: Upper respiratory tract infections are major causes of the common cold throughout the world. Cordyceps militaris (C. militaris) is a well-known functional food for its anti-fatigue and immunomodulating activities. On the other hand, there are no reports on the protective effect against upper respiratory tract infections (URI). This study was a 12 week randomized, double-blind, and placebo-controlled trial in healthy volunteers. Methods: A total of 100 subjects 20 ~ 70 years of age with a history of at least two colds in the year were enrolled in the study. The participants were required to record any adverse events and rate any cold-related incidents in a diary during the investigation period. The efficacy end point was the symptoms and incidence of URI, and changes in cytokines, IgA and natural killer (NK) cell activity. Results: The Cordyceps militaris group over 12 weeks showed no significant impact on the incidence and symptomatology of URI compared to the placebo group. On the other hand, the experimental group showed significantly higher NK cell activity (p = 0.047) and IgA level (p = 0.035) compared to the placebo group. The NK-cell activity and IgA level were increased significantly by Cordyceps militaris over 12 weeks. Conclusion: The results suggest the possible beneficial immunomodulating effects, but the protective effects on URI could not be demonstrated under these conditions. Additional research will be needed to determine the efficacy and mechanisms of Cordyceps militaris function.

수족냉증(手足冷症) 환자(患者)에 대(對)한 컴퓨터 적외선(赤外線) 체열촬영(體熱撮影)의 의의(意義)

조유경,오수완,조남희,김동묵,김진성,류봉하,박동원,류기원,Cho, Yu-Kyung,Oh, Su-Wan,Cho, Nam-Hee,Kim, Dong-Mook,Kim, Jin-Seong,Ryu, Bong-Ha,Park, Dong-Won,Ryu, Ki-Won 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.2

To make a objective diagnosis of the syndrome of cold-limbs, We investigated the 20 patients with cold limbs and GI trouble and 20 normal people as a control group. And we compared the thermal difference between Chon-jung(CV17) and Chung-wan(CV12 中脘), Chon-jung(CV17) and Ki-hae(氣海 CV6) and we compared the thermal differences of No-gung(PE8 勞宮) and Yong-chon(湧泉 KI1), too. The results were as follows. 1. All 20 patients had GI trouble and cold limbs. They had the symptom-Indigestion(16 cases-80%) with heart burn, tympanites, abdominal distention, hiccup, belching. Beside that symptom they also had constipation(6 cases-30%), diarrhea(3 cases-15%), headache & dizziness(6 cases-30%). And some had the menstrual syndrome, chronic fatigue, palpitation, insomnia, edema, arthralgia. 2. The thermal difference of the palms between the patients group and the control group were $25.70^{\circ}C,\;25.82^{\circ}C$, but they were not significant. 3. The thermal difference of the soles between the patients group and the control group were $23.58^{\circ}C,\;24.42^{\circ}C$ and the significancy was P=0.020 so it was significant(P<0.05). 4. The thermal difference of the palms and Chon-jung(CV17) between the patients group and the control group were $1.08^{\circ}C,\;0.76^{\circ}C$, but they were not significant. 5. The thermal difference of the sales and Chon-jung(CV17) between the patients group and the control group were $3.01^{\circ}C,\;1.90^{\circ}C$ and the significancy was P=0.003 so it was significant(P<0.05). 6. The thermal difference of Chon-jung(CV17) and Chung-wan(CV12 中脘) between the patients group and the control group was $0.30^{\circ}C,\;0.62^{\circ}C$ and the significancy was P=0.793 so it was significant(P<0.05). 7. The thermal difference of Chon-jung(CV17) and Ki-hae(CV6 氣海) between the patients group and the control group was $0.53^{\circ}C,\;0.68^{\circ}C$, but they were not significant. From the above, I could find the significance of D.I.T.I to diagnose the cold-feet not the cold-hands and the thermal difference between the trunk and limbs was more significant on cold-feet than on cold-hand, either.

지체장애인의 자가운전에 대한 부산지역 일반인들의 인식도 조사

차수민 ( Su Min Cha ),이지원 ( Ji Won Lee ),오현정 ( Hyeon Jeong Oh ),이수완 ( Su Wan Lee ),이지숙 ( Ji Sook Lee ) 고령자·치매작업치료학회 2015 고령자.치매작업치료학회지 Vol.9 No.1

목적: 본 연구는 지체장애인의 자가운전에 대한 일반인들의 인식도를 파악하고자 부산지역 일반인을 대상으로 자가운전의 필요도와 요구도를 조사함으로써 차후 운전재활 활성화 방안 마련을 위한 기초자료 제시하고자 하였다. 연구방법: 2014년 5월 10일부터 5월 23일 까지 부산지역의 일반인 150명을 대상으로 지체장애인의 자가운전에 대한 인식도를 조사하기 위해 방문설문조사를 실시하였다. 연구결과: 대부분 지체장애인의 경우 안전운전이 어렵다는 인식을 가지고 있었다. 하지만 장애인의 자가운전의 필요성 및 욕구에 대해서는 이동권을 확보하기 위해 필요하다고 하였고, 이를 위해 교육이나 훈련시설 및 인력 확충이 요구된다고 하였다. 결론: 일반인들의 장애인들의 자가운전에 대한 인식개선이 필요하고, 지체장애인들을 대상으로 전문적이고 체계적인 운전재활 시스템 활성화가 필요하다. 또한 이를 뒷받침하기 위한 관련 법 및 제도개선이 필요할 것이다. Objectives: The purpose of this study was to present the basis for the necessary help enable future driving rehabilitation plan prepared by examining the public awareness of busan on self-driving by the people with physical disability. Methods: From May 10th, 2014 to May 23th, 2014 visit to the surveys were conducted to examine the operation of the self-awareness of the handicapped for the public 150 people in Busan. Results: For most of the physically disabled had to recognize safe driving is difficult. But the move was necessary to secure the rights for the disabled driving needs and desires of the self, and that the expansion of education and training facilities and personnel required for this purpose. Conclusion: Driving awareness of the need to improve the public for the disabled and handicapped targeted at professional and systematic driving rehabilitation system activation is required. In addition, laws and institutions will be needed to support this improvement.

지능형 CCTV 기반 동적 범죄예측 기술 동향

박상욱,오선호,박수완,임경수,최범석,박소희,김상원,한승완,한종욱,김건우,Park, Sangwook,Oh, Seon Ho,Park, Su Wan,Lim, Kyung Soo,Choi, Bum Suk,Park, So Hee,Ghyme, Sang Won,Han, Seung Wan,Han, Jong-Wook,Kim, Geonwoo 한국전자통신연구원 2020 전자통신동향분석 Vol.35 No.2

Predicting where and when a crime may occur in an area of interest is one of many strategies of predictive policing. Multidimensional analysis, including CCTV, can overcome the limitations of hotspot prediction, especially of violent crimes. In order to identify the precursors of a crime, it is necessary to analyze dynamic data such as attributes and activities of people, social information, environmental information, traffic flows, and weather. These parameters can be recognized by CCTV. In addition, it provides accurate analysis of the circumstances of a crime in a dynamic situation, calculates the risk, and predicts the probability of a crime occurring in the near future. Additionally, it provides ways to gather historical criminal datasets, including sensitive personal information.

기훈 환자의 補虛飮 투여 후 호전 1례

김진석(Jin-Seok Kim),홍종희(Jong-Hee Hong),박재우(Jae-Woo Park),전우현(Woo-Hyun Jeon),조남희(Nam-Hee Cho),오수완(Su-Wan Oh),김진성(Jin-Seong Kim),류봉하(Bong-Ha Ryu),류기원(Ki-Won Ryu) 대한한의학회 2000 대한한의학회지 Vol.21 No.4

과민성대장증후군의 변증 유형과 양도락 결과의 분석

오수완,조남희,전우현,박재우,김진석,홍종희,김진성,류봉하,류기원 대한한방성인병학회 2000 韓方成人病學會誌 Vol.6 No.1

Objectives : The aim of the present study was to find the clinical characteristics of 3 symptom- complexes (① deficiency of Ki of the spleen(脾氣虛) ② insufficiency of Yang of the spleen and kidneys(脾腎陽虛) disharmony of the liver & spleen(肝脾不和)) of irritable bowel syndrome and test the potentiality of the skin resistance check(良導絡) to apply it in clinical diagnosis. Methods : 42 of 72 patients who visited KHMC 3rd medicine with suspicious IBS were underwent questionnaire and skin resistance check. The questionnaire was composed of 46 questions inquiring sex, age, duration, stool type, previous medication, and systemic symptoms. Results : 1. The prevalence of above 3 symptom-complexes of irritable bowel syndrome was shown as below : deficiency of Ki of the spleen(脾氣虛) 23.8%(n=10), insufficiency of Yang of the spleen and kidneys(脾腎陽虛) 26.2%(n=11), disharmony of the liver & spleen 50.0%(n=21). 2. Symptom-complex 'insufficiency of Yang of the spleen and kidneys' has manifested only diarrhea while others shown approximately same occurrence of diarreha and alternative diarrhea-constipation. 3. Anorexia appeared comparatively seldom in symptom-complex 'disharmony of the liver and spleen'. 4. There was no statistical significance between skin resistance check results and symptom-complexes. Conclusion : The prevalence of symptom-complex type of irritable bowel syndrome is shown as 'disharmony of the liver & spleen' (50.0%) > 'insufficiency of Yang of the spleen and kidneys' (26.2%) >= 'deficiency of Ki of the spleen' (23.8%) and skin resistance check seems not to be appropriate to be applied in diagnosing symptom-complexes of irritable bowel syndrome.

한방 치료로 호전을 보인 흉선종을 동반한 중증 근무력증 환자 1례

홍종희,박재우,김진석,전우현,조남희,오수완,김진성,류봉하,류기원 대한한방성인병학회 2000 韓方成人病學會誌 Vol.6 No.1

Myasthenia Gravis is an autoimmune disorder characterized by fluctuating muscle weakness and fatigue of different muscle groups. Diagnostic tests include use of anticholinesterase agents(Tensilon test), curare test, repetitive nerve stimulation, acetylcholine-receptor antibody assay and single fiber electromyography. Medical therapy includes use of anticholinesterase agents, immunotherapy, plasmapheresis and thymectomy. We report a case of Myasthenia Gravis diagnosed by acetylcholine-receptor antibody assay, EMG and thymoma on the chest-CT. The major clinical symptoms were low back pain, waddling gait, weight loss and fatigue. This patient was diagnosed as Wea Jeung(위증) and treated by Herbal-medication based on the differentiation of syndromes. As we treated, some of his symptoms were improved.