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양상인,이승진,박하영,이상호,장춘곤,이완석,신영희,김정주,이석용 대한약학회 2003 약학회지 Vol.47 No.2
Due to its profound intestinal first-pass metabolism, oral eperisone hydrochloride produces a very low bioavailability and a very short muscle relaxant activity. To improve the efficacy and compliance of eperisone, we designed a new dosage form, the transdermal patch and evaluated the muscle relaxant effects of this patch in rats. The muscle relaxant activity was assessed by measurement of forelimb grip strength and hanging test in rats. The transdermal patch of eperisone hydrochloride showed significant muscle relaxant activity at 0.5, 1.5 and 3 cm$^2$/200 g rat (1.39, 4.17 and 8.33 mg of eperisone hydrochloride/kg, respectively) in a dose-dependent manner and the effects were lasted over 24 hours. The oral eperisone hydrochloride showed significant activity at 12.5, 25 and 50 mg/kg in a dose-dependent manner but the activity was within 1 or 2 hours after administration. These results suggest that the eperisone hydrochloride is absorbed efficiently from transdermal patch and the patch can exert potent and long-lasting muscle relaxant activity. This transdermal patch will increase the efficacy and compliance in the clinical use of eperisone hydrochloride.
양상백,장세은 韓國海洋大學校 人文社會科學大學 1999 韓國海洋大學校 人文社會科學論叢 Vol.- No.7
The purpose of this paper is to examine some aspects of wh-questions in American Sign Language (ASL), and to discuss some of the significant points in dispute about two current conflicting analyses of the rightward and leftward wh-movement. It has been discussed that some common examples of undisputed grammatical wh-sentences in ASL can be accounted for by either of two hypotheses: a leftward movement hypothesis that spec-CP and wh-movement is leftward universally, a rightward movement hypothesis that spec-CP and wh-movement is rightward. Nonetheless, in ASL, the rightward wh-movement analysis has been predominant over the leftward wh-movement analysis, even though the former provides a counterexample to claims by Kayne (1994) that all phrasal projections exhibit specifier-head-complement order and that syntactic movement is leftward, and thus it calls for an additional device that universal grammar must handle to allow the option of rightward movement. Two convincing arguments in favor of rightward analysis are (ⅰ) generalization of distribution of nonmanual syntactic wh-marking and (ⅱ) extraction of wh-words from within an embedded clause. In contrast, there are three pieces of evidence in favor of leftward wh-movement: (ⅰ) focus function of right-peripheral wh-material in wh-doubles sentences, given no occurrence of complex wh-phrases at the end of the sentence, (ⅱ) null arguments and covert wh-words, and (ⅲ) multisentence discourses in which the first sentence presents the presupposed information, and the second the single wh-word question. Our conclusion drawn from comparison of two contradictory analyses is that a major cause for this different views stems from different grammatical judgments on the same data, and this different interpretation of various wh-questions is due to at what level grammaticality is considered. Advocates of rightward wh-movement consider it at the sentence level only, while those of leftward wh-movement consider it at the discourse level for the most part. We hope that this paper will be contributed to studying Korean Sign Language with special regard to nonmanual signals and wh-questions.
양상선(Sangsun Yang),장윤형(Yoon-Hyung Jang),김창혁(Chang Hyuk Kim),황창선(Changseon Hwang),채석병(Sukbyung Chae),정세권(Sekwon Jung),이정훈(Jeonghoon Lee),최만수(Mansoo Choi) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.5
Flame metal combustion method for continuously synthesizing metal oxide nanoparticles with a high production rate was proposed. Micro-sized metal powder precursors injected into a hydrogen-oxygen flame were converted into metal oxide nanoparticles with good crystallinity. There is no limitation in the selection of precursors including metal chloride and metal organic powders to synthesize nanoparticles. Various oxides such as magnesia, iron oxides and zinc oxide were generated by using this method. The sizes of oxide nanoparticles were found to be dependent on flame temperatures and residence times.
평면 방향의 구속조건과 들러붙음 현상을 고려한 사출성형제품의 변형 해석
양상식(S. S. Yang),권태헌(T. H. Kwon) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11
Deformation analysis of injection molded articles whose geometry is considered as the assembly of thin flat plates has been conducted by simulation and experiment. For the simulation, the thermoviscoelastic stress and the in-mold deformation are calculated during in-mold analysis. Emphasis is made on lateral boundary conditions considering in-plane mold constraint and sticking effect between part and mold wall. Upon ejection, the instantaneous deformation takes place. During an out-of-mold cooling, the thermoviscoelastic model based on the effective temperature is used. The free volume theory is employed to represent the nonequilibrium density behavior during fast cooling. For the experiment, the shrinkage of PS parts was measured. Two mold geometries, square flat plate and one with two side walls, were tested. Parametric study was performed to investigate the effect of processing conditions on the shrinkage. Measured shrinkages were compared with simulation results.
양상백 동서대학교부설연구소 1997 연구소 논문집 Vol.2 No.-
The purpose of this paper is to show that English cleft and inverted constructions bringing about some syntactic movements would trigger focus movement at a level of syntactic movements would trigger focus movement at a level of syntactic representation. To do so, we will examine some arguments for focus projection of a focussed element in the English clausal structure. We will consider preposed negative consituents and it-clefted constituents as a constructional focus elements. And I will suggest taht F, head of Focus Projection, decides the type of focus construction and it has one of the feature combination of [±wh, + it has one of the feature combination of [±wh, ±focus]. Especially, it-cleft has [+wh, +focus] feature and then it has to move at the SOEC of CP to check the feature.
Surgical Jaw Relator를 이용한 Surgical splint의 제작
양상덕,Yang, Sang-Duck 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.2
After making the surgical treatment plan, the surgical movements are duplicated in the model surgery. During this procedure, reference points and lines are drawn on the base of the models over the dental arch, and sawcuts are made according to these marked osteotomy lines. This method requires more accuracy for better postsurgical results in that the surgical splint which enables the surgeon to position the jaws intraoperatively is made from the casts as repositioned by the model surgery, and finally it will define the postsurgical results. This technique, however, has been found to be inexact, especially when the jaws are moved in several dimensions simultaneously. To overcome this, different methods have been developed for an accurate repositioning of the jaws as planned. A new appliance, Surgical Jaw Relator, was devised by the author for the simple 3-dimensional relocation of the upper and lower models, resulting in the easy construction of the splints such as centric relation splint, intermediate and final splint. This article describes an introduction and a clinical application of this appliance.