고양이 전염성복막염의 자연감염 예

배유찬,진영화,소병재,손현주,윤순식,김기석,위성환,김옥경,강문일,우유석,Bae You-chan,Jean Young-hwa,So Byung-jae,Sohn Hyun-joo,Yoon Soon-seek,Kim Ki-seuk,Wee Sung-hwan,Kim Ok-kyung,Kang Mun-il,Reinacher Manfrde,Woo Yoo-suk 대한수의사회 2001 대한수의사회지 Vol.37 No.5

A 8 month old, female Domestic Shorthair cat with long-term signalment of anorexia, lacrimation, uveitis and coughing was submitted to the Pathology and Diagnosis Reference Division, NVRQS, Korea, for necropsy. Main gross lesions were characterized by asc

無菌實驗動物 마우스의 育成에 따른 內外部 寄生蟲 未感染 證明

Yung Bai KANG(姜英培),Byung Jae SO(蘇秉宰),Keun Sik PARK(朴根植) 한국예방수의학회 1988 예방수의학회지 Vol.12 No.2

A laboratory trial was carried out for the evidence of internal and external parasites in the laboratory maintained germfree mice. The results obtained were summarized as follows. 1. The reproductive performance of the germfree mice was revealed as 100% pregnancy rate and 19.6 days of pregnancy period compared with 92.0% and 19.2% days, respectively, in the conventional mice. 2. None of the internal and external parasites was detected from the germfree mice. 3. Common parasites infesting the conventional mice were detected as 22.7% Hymenolepis diminuta, 27.3% of Syphacia muris and 45.5% of Mycoptes musculinus.

북한산 국립공원 주변지역 사육견의 광견병 항체 분포조사(2)

채희선 ( Hee Sun Chae ),소병재 ( Byung Jae So ),김두환 ( Doo Hwan Kim ),조미영 ( Mee Young Jo ),배니수 ( Nae Soo Bae ),기노준 ( No Joon Ki ),이병동 ( Byung Dong Lee ) 한국가축위생학회 2002 韓國家畜衛生學會誌 Vol.25 No.1

Recently, the rabies cases have been reported in Paju-and Yangju-gun, Gyeonggi province near Seoul metropolitan area. The Pukhansan national park, nearly located from the cities, is suspected to be a high risk area for incidence and spread of the rabies to metropolitan area. This study was conducted to investigate the prevalence rate for rabies antibody of dogs near the Pukhansan national park and in some other districts in Seoul metropolitan city. From march to october 2001, a total of 306 serum samples were taken from dogs for breeding(189) and pet dogs(117) in 4 districts near the Pukhansan national park and other districts of Seoul. Rabies virus antibodies in sera were detected by neutralizing peroxidase-linked assay(NPLA). Of the 306 sera of dogs tested, 74(24.2%) were positive to rabies virus antibody. The prevalence rates of rabies antibody in Pukhansan national park area and in the other districts of Seoul city were 23.7% and 25.3%, respectively. There was no significant difference in the prevalence rate between these two districts. The prevalence rates of rabies antibody in pet dogs and dogs for breeding were 40.2% and 14.3% respectively. The prevalence rates of rabies antibodies in less than 1 year, 1~<2 years, 2~<3 years, and over 3 years old dogs were 14.5%, 22.4%, 32.6%, and 27.1%, respectively, and overall 24.2% in the dog population. In addition, we found that dogs less than 1 year old had lower antibody prevalence than those over 1 year old. It was concluded that enhancement of vaccination is important in the prevention of the rabies, and that rabies vaccines should not be less supplied than the population of the dog.

도축 젖소에서 발생한 악성 난소생식세포종 증례보고

정지열,허지웅,정예지,구경녀,최권락,소병재,윤순식,Jung, Ji-Youl,Her, Ji-Woong,Jeong, Yea-Ji,Ku, Kyung-Nyer,Choi, Kwon-Rac,So, Byung-Jae,Yoon, Soon-Seek 대한수의학회 2015 大韓獸醫學會誌 Vol.55 No.2

An abnormally enlarged right ovary and a mass in fat surrounding the right kidney were discovered in a dairy cow during routine postmortem examination at slaughter. The ovary was dark reddish and multinodular in shape. Numerous cystic structures were identified in the mass. Histopathologically, the ovary was completely replaced with large, uniform, polyhedral neoplastic cells containing vesicular nuclei and prominent nucleoli. The mitotic index was high. In the lymphatic vessels, tumor emboli were observed. Another mass in the fat surranding the right kidney had the same histological features as the ovarian mass. This animal was diagnosed with malignant dysgerminoma and metastasis to other peritoneal organs.

도축 젖소에서 Trueperella pyogenes 감염에 의한 턱 밑 화농육아종 증례보고

정지열 ( Ji-youl Jung ),정재훈 ( Jae-hun Jeong ),김하영 ( Ha-young Kim ),오상익 ( Sang-ik O ),류대열 ( Dae Yeol Ryu ),윤형록 ( Hyoung Lok Yoon ),소병재 ( Byung Jae So ),윤순식 ( Soon-seek Yoon ) 한국동물위생학회 2016 韓國家畜衛生學會誌 Vol.39 No.1

Multiple enlarged submandibular nodules were discovered during a routine antimortem examination at slaughter in 3 dairy cows of 20-month-old. Grossly, submandibular nodules were firm, reddish, and oval in shape. On cut surface, multiple yellowish abscesses in the parenchyma were observed. Histopathologically, the nodules were characterized by severe diffuse pyogranulomatous inflammation and chronic fibrosis with multiple eosinophilic clubs of Splendore-Hoeppli material containing central bacterial colonies. Trueperella pyogenes was isolated from the lesions. This case was diagnosed as submandibular pyogranuloma caused by Trueperella pyogenes in slaughtered dairy cows in Korea.

근대수의역사자료 번역 및 편찬활동 (1868-1938)

심유정 ( Yu Jung Sim ),이길섭 ( Kil Seob Lee ),소병재 ( Byung Jae So ),최정업 ( Cheong Up Choi ) 한국농업사학회 2010 농업사연구 Vol.9 No.2

역사적으로 한국 정부기관에서 수의에 관련된 업무를 시작했던 시기는 고려(918~1392) 말로 당시 수의사의 역할은 군사용 말의 질병예방과 치료를 담당했었다. 근대에 들어와 설립된 국립수의과학검역원의 모태인 수출우검역소와 우역혈청제조소는 1909년 한국에서 최초로 현대적인 수의업무를 수행한 정부기관이다. 가축질병을 연구하던 우역혈청제조소에서는 가축질병 연구 및 수의학 전반에 관한 많은 국내외 도서를 소장하고 관련 자료를 발간하였다. 현재 국립수의과학검역원에서는 1856~1945년 도서를 431종 3,347권(동양서 215종 1,431권, 서양서 216종 1,916권) 소장하고 있다. 2006년부터 일제강점기시대에 작성된 가축질병연구와 방역사항을 기술한 주요 수의서에 대해 활용도를 높이고, 보존을 강화시키기 위해 고서보존사업을 시작하였다. 대부분 일본 고어로 쓰여 있어 활용도가 떨어지고 해석이 어려웠으나 고증을 통해 현대 국어로 번역작업을 하여 이해하기 쉽도록 1,2차에 걸쳐 총8권(p.3,375)의 국역서를 출간하였다. 이 책에는 동북아지역의 우역 발생현황, 예방용 혈청제조 방법, 생산량, 효력시험, 원인바이러스의 특성조사뿐만 아니라 소의 주요 기생충질병(주혈필라리라, 폐디스토마)과 닭의 뉴캣슬병, 추백리, 가금콜레라, 계두 백신개발, 돈두 등 당시의 다양한 가축질병의 발생상황을 파악할 수 있다. 또한, 우역, 탄저, 구제역 등 그 시기의 가축질병 방역상황과 가축질병 예방법, 검역규정, 가축방역과 검역기구 등 근대 수의학의 변천사에 대한 폭넓은 정보를 제공하고 있어 수의·축산 연구자들에게 도움을 주고 있다. 가축질병의 퇴치는 축산업을 발전시키고 안전한 식탁을 책임진다. 과거의 기술을 토대로 미래의 과학기술이 성장하므로 고서의 활용과 보존은 중요하다. 국립수의과학검역원에서는 2009년 기관설립 100주년을 맞아 검역원의 과거와 현재 미래를 기술한 100년사를 발간했으며, 100년사 발간사업을 통해 수집한 자료와 사진, 수의 관련 유물을 정리하여 보존하고 있다. 향후 고서보존을 위해 수장고 설치와 사료관을 건립할 예정이다. 또한, 소장하고 있는 주요 수의고서에 대한 국역화를 계속할 뿐만 아니라 국내·외에 있는 주요한 수의고서에 대하여도 적극적인 수집과 발굴을 통해 수의 관련 역사자료가 사장되지 않도록 할 예정이다. 이 사업이 근대수의학을 연구하는 연구자들에게 도움이 되었으면 하고, 나아가 농업사학 연구가 지속적으로 발전하길 바란다. The Royal institutions had carried out veterinary tasks late in the Goryeo dynasty (918-1392) reportedly. At that time, veterinarians in the institutions took charge of disease prevention and treatment for military horses. Quarantine Service for Cattle Export (1909) and Rinderpest Antiserum Manufacture Institute (RAMI) (1911) that were the mother institutes of NVRQS, had been established as the first modern veterinary institutions in Korea. Many domestic and foreign books in the field of animal disease research and veterinary science had been kept in RAMI and this institute published many books relating to those fields. As a result, currently NVRQS posseses 3,347 volumes of 431 kinds which are 1,431 volumes of 215 kinds for Oriental books and 1,916 volumes of 216 kinds for the Western books collected from 1856 to 1945. Since 2006, to enhance the availability and preserve the contents of the archive recorded during the Japanese occupation era kept in NVRQS, we have initiated the NVRQS Veterinary Historical Archive project. Because most of them were written in old style Japanese language, it was difficult to understand and use them. So throughout historical research and careful investigation, we could translate them into Korean version It was a total of 8 volumes (3,375 pages) of books. Particularly, they include the reports investigating the outbreaks of rinderpest in Northeast Asia, characterizing its etiological agent and summarizing the methods for producing sera for the purpose of disease prevention. In these reports the quantity of the production and efficacy test results for them are also included. Furthermore, the dissemination of the major bovine parasitic diseases (pulmonary distoma and blood filaria) and Newcastle disease, pullorum disease, fowl cholera, fowl pox vaccine development, swine pox during the period ware described in that book. Because they deliver a lot of facts or events in the history of veterinary services in those days (e.g. the disease control efforts for rinderpest, anthrax and foot-and-mouth disease) and they convey the regulations or organizational information for disease control, quarantine or disease prevention at that time, they would be very informative to the related people even in these days. The successful veterinary services play essential role for livestock industry and contribute importantly to the food safety. All the required knowledges and technologies in the field of veterinary services for them are developed on the basis of the present and past experiences, so the use and preservation of old books are so important. NVRQS published 100 year-history describing the future and the past of NVRQS to celebrate its 100th anniversary in 2009. The old data, reports, photographs and records collected during the publication of100 year-history had been listed and preserved. Afterwards, the separate storage room for the historical archive is going to be built. Moreover, we will continue to do additional translation for the left and collect old veterinary books from outside or abroad to keep them from being lost and also make them preserved and useful. We expect that the people concerned in this fields can benefit greatly from this project of NVRQS Veterinary Historical Archive initiated from 2006 and there would be a continuous development in the field of agricultural and veterinary researches.

PRRSV와 Staphylococcus hyicus 복합감염에 의한 돼지 귀 괴사 증후군 증례 보고

이승희,정지열,김성희,김종완,박중원,강대영,허지웅,정예지,소병재,윤순식,Lee, Seunghee,Jung, Ji-Youl,Kim, Seong-Hee,Kim, Jong-Wan,Park, Jung-Won,Kang, Dae-Young,Her, Ji-Woong,Jeong, Yea-Ji,So, Byung Jae,Yoon, Soon-Seek 대한수의학회 2017 大韓獸醫學會誌 Vol.57 No.2

Porcine ear necrosis syndrome is characterized by erosive and ulcerative lesions at the margin or tip of the pinna. Three growing pigs of different ages exhibited retarded growth accompanied by reddening and necrosis of ear prior to death. Gross examination showed reddening, swelling, black discoloration, scaling, and variable-sized yellowish materials and edema in ear cross section. Microscopically, thrombosis, abscess, ulceration, epidermal hyperplasia, and dermal pyogranulomatous inflammation with an intralesional bacterial colony were observed. Staphylococcus hyicus was isolated in all pigs' ears and porcine reproductive and respiratory syndrome virus was detected by PCR and immunohistochemistry.

고양이 전염성복막염의 자연감염 예

배유찬 ( You Chan Bae ),진영화 ( Young Hwa Jean ),소병재 ( Byung Jae So ),손현주 ( Hyun Joo Sohn ),윤순식 ( Soon Seek Yoon ),강문일 ( Mun Il Kang ),( Manfred Reinacher ),우유석 ( Yoo Suk Woo ),김기석 ( Ki Seuk Kim ),김영환 ( Yo 한국가축위생학회 2003 韓國家畜衛生學會誌 Vol.26 No.1

A 8 months old, female domestic Shorthair cat with long-term signalment of anorexia, lacrimation, uveitis and coughing was submitted to the Pathology and Diagnosis Reference Division, NVRQS, Korea, for necropsy. Main gross lesions were characterized by ascities, some grayish-white nodular formation and fibrous adhesion on the surface of visceral organs including liver and kidney. Principle histopathological findings were fibrinous serositis, multifocal granuloma and necrosis, vasculitis, perivasculitis in various pharenchymal organs. Paraffin-embedded tissue sections taken from most of organs with granulomatous lesions were confirmed specific reaction to the monoclonal antibody of feline infectious peritonitis virus in the cytoplasm of many infiltrating macrophages by immunohistochemistry. The report was to describe the pathological lesions of the first naturally-occuring FIP case in companion cat of Korea.

독일세퍼드견에서의 폐전이 소견의 양측성 신장 낭선암종

박우희 ( Woo Hee Park ),류문영 ( Moon Young Rhyoo ),이현경 ( Hyun Kyoung Lee ),최은진 ( Eun Jin Choi ),소병재 ( Byung Jae So ),이경현 ( Kyung Hyun Lee ) 한국동물위생학회 2015 韓國家畜衛生學會誌 Vol.38 No.4

Primary renal tumors are uncommon in dogs with prevalence rate of approximately 1%. Renal carcinoma originating from epithelium of proximal convoluted tubules are more likely to be affected to Middle-aged dogs (average age, 8y), males about twice as often as bitches. A 10-year-old, female, German Shepherd dog with history of anorexia, vomitting and hematuria was referred to the Animal Disease Diagnostic Division in Animal and Plant Quarantine Agency. The dog was necropsied and several organs were collected, fixed in 10% phosphate-buffered formalin, embedded in paraffin wax and sectioned for histopathology. Grossly, the kidneys were bilaterally enlarged (18×12×8 cm; left, 18×10×8 cm; right). The numerous cysts varying sizes from 3 to 6 cm in diameter were protruding from the surface of both kidney. A large nodule (10×6×6 cm) was discovered between cardiac and diaphragmatic lobe in the right lung. Immunohistochemical examination revealed strong positive reaction to cytokeratin and ki-67 in the nuclei of the epithelial tumor cells. But showed negative reactions to vimentin and CD10. Based on the pathological and immunohistochemical examination, we diagnosed as the bilateral renal cystadenocarcinoma in German shepherd dog.

국내 야생동물의 광견병 감염실태 조사

소병재,진영화,이상직,이은동,이경기,황의경,이상경,김재훈,박최규,윤순식,김기석,문운경,신명균,이성식 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.2

This study was conducted to investigate the current status of rabies in wild animals and to elucidate the wild animal transmitting rabies to domestic animals in the Republic of Korea. Through epidemiological survey of rabies near the Demilitarized Zone(DMZ) in Kyonggi and Kangwon Provinces, we found that raccoon dogs( Nyctereutes procyonoides) transmitted rabies to domestic animals in the infected area.To do this we tested the sera or/and brain tissue collected from 8 kinds of wild animals( Nyctereutes procyonoides, Meles meles, Lepus coreanus, Apodemus agrarius, Eothenomys regulus, Felis catus, Mutela sibirica coreana, Martes flavigula aterrima). Only raccoon dogs showed positive reaction in fluorescent antibody test. Naturally acquired antibodies against rabies virus could not be detected in other animals as well as raccoon dogs captured in the rabies infected and non-infected area in Korea. Antibodies against rabies virus could not be detected even raccoon dogs diagnosed with rabies. Therefore, it is considered that raccoon dogs would die before forming antibodies against rabies virus, if infected.