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서신원,양혜영 한국품질경영학회 2022 한국품질경영학회 학술대회 Vol.2022 No.1
신약개발비의 급격한 증가로 인하여 제약회사들의 생산성에 대한 이해를 목적으로 한 다양한 연구들이 수행되었다. 제약회사 연구개발의 핵심과정인 임상시험 단계가 제약회사의 생산성에 영향을 주는 단계라고 할 수 있음에도 불구하고 그동안 임상시험 단계는 크게 주목받지 않았다. 이에 본 연구에서는 제약회사의 생산성과 특허 및 임상시험의 관계를 알아보고자 하였다. 임상시험 데이터와 특허데이터 그리고 매출액 데이터를 활용하여 머신러닝 알고리즘 중에서 강력한 성능을 자랑하는 알고리즘 중 하나인 랜덤 포레스트를 이용하여 기업의 매출 성장을 예측하는 연구를 수행하였다. 특허 데이터만 사용한 모형과 특허 및 임상시험 데이터를 동시에 사용한 모형의 예측력을 비교하여 임상시험 데이터의 유무가 예측력에 어떠한 영향을 끼치는지 알아보았다. 그 결과 특허 및 임상시험 데이터를 동시에 사용한 모형의 정확도와 F1-척도가 대체적으로 높게 나타났다.
공급률 및 탈곡통 길이 변화에 따른 자탈형 콤바인 탈곡 성능
서신원,이상우,허윤근 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.2
Threshing loss was increased due to dropping of the threshing efficiency when the 4 row head-feed combine harvested 5 row rice to improve harvesting performance of a combine. Reasonable design criteria were examined to determine the ranges of both of feed rate and the length of threshing drum for the 4 row head-feed combine being used as a 5-row combine. Harvesting performance increased as working width or working speed increased, it resulted in 15% increase when the working width increased from4 row to 5 row. Harvesting operations of the 4 row combine performed normally in the 4 row rice in threshing loss less than 1%, however, threshing loss increased to 2.25% in the 5 row due to poor threshing efficiency. The length of threshing drum was increased from 710 mm to 810 mm as well as the speed of crop feed chain was increased from 0.61 m/s to 0.75 m/s so as to improve the poor threshing efficiency resulted from the enlarged working width from the 4 row to the 5 row, which would decrease threshing loss less than 1%.
서신원,양혜영 한국콘텐츠학회 2023 한국콘텐츠학회논문지 Vol.23 No.1
Due to the rapid increase in new drug development costs, various studies have been conducted to understand the productivity of pharmaceutical companies. Although the clinical trial is the core process of research and development for pharmaceutical companies and affects the productivity, the clinical trial has not received much attention. In this study, assuming that not only patents but also clinical trials are related to the increase in sales of pharmaceutical companies, the high-growth in sales was predicted through machine learning analysis using the number of patents and clinical trials. Using clinical trial data, patent data, and revenue data, a study was conducted to predict a high-growth of company's revenue using Random Forest, one of the machine learning algorithms. The predictive performance of the model using only patent data and the model using both patent and clinical trial data was compared to find out whether clinical trial data affects the predictive performance. As a result, the accuracy and F1-scale of the model using both patent and clinical trial data were generally high.
서신원(Sin-Won Seo),허윤근(Yun-Kun Huh),이제용(Je-Yong Lee),이창규(Chang-Kyu Lee) 충남대학교 농업과학연구소 2010 농업과학연구 Vol.37 No.2
Electro-hydraulic transmission (HST) and an electronic control system was designed, and performance of the components were investigated through indoor tests. When input values for HST swash plate control were given at 3 levels (5, 10, 13 degrees) in forward and reverse directions, the errors were less than 0.6 degrees. Response time was in ranges of 0.14 ~ 0.16 s and 0.16 ~ 0.2 s for forward and reverse direction controls while driving, and the values were 0.23 ~ 0.25 s and 0.18 ~ 0.23 s at static condition, respectively. Similar experiments for left and right steering resulted errors less than 0.5 degrees. Resonse time was in ranges of 0.16 ~ 0.22 s and 0.11 ~ 0.23 s for left and right turns while driving, and the values were 0.07 ~ 0.21 s and 0.09 ~ 0.14 s at static condition, respectively. From frequency response experiments, control system appeared to follow sine waves appropriately at frequencies less than 0.8 ㎐ with gain of 0.11 ㏈ and 0.09 ㏈ for forward and reverse direction controls, respectively, and the gain decreased above the frequency. Phase difference showed a gradual increase and were less than 45 degree up to 0.8 ㎐. Similar experiments for left and right streering showed that the control system appeared to follow sine waves appropriately at frequencies less than 0.8 ㎐ with gain of 0.28 ㏈ and 0.26 ㏈ for left and right steering controls, respectively, and the gain decreased above the frequency. Phase difference showed a gradual increase and were less than 45 degree up to 0.8 ㎐, which was the same as for the forward and reverse controls.
서신원(Sin-Won Seo),허윤근(Yun-Kun Huh),이제용(Je-Yong Lee),이창규(Chang-Kyu Lee),배근수(Keun-Soo Bae) 충남대학교 농업과학연구소 2011 농업과학연구 Vol.38 No.1
I/An electro-hydraulic transmission having advantages of convenience, safety, simple linking and high power, and an electronic control system were designed and fabricated. In this study, characteristics of the control system were investigated through outdoor tests for evaluation of installation of the system on a combine. Major findings were as followings. 1. Experiment for performance evaluation of the control system was conducted on concrete road. With steering lever in neutral position, driving HST swash plate and left/right wheel speed increased in proportion to driving lever angle. In case of steering control, steering swash plate angle changed in proportion to steering lever angle. This should cause increase in outer wheel speed, but it was observed that HST swash plate was controlled toward neutral to maintain the speed before steering. As a result, speed before steering was maintained despite the change in outer wheel speed by steering HST swash plate angle change. 2. It was observed that the HST system enabled steering with outer wheel maintained at constant speeds while inner wheel speed decreased, which was more stable than conventional mechanical links. In addition, for the selected 5 criteria, experiment showed satisfactory results and it was judged that installation on real vehicle would be feasible. 3. The control system showed response property of appropriate forward/reverse movement and lift/right steering, without causing any problems during experiment on concrete. Result of response property experiment on field operation also showed appropriate control over forward/reverse movement and left/right steering
신미옥,서신원,송복례,김경희,윤건호,유양숙,김희승 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1
Background : The aim of this study was to examine the effectiveness of the critical pathway to diabetic patients who were admitted in the hospital. Methods : For establishment of critical pathway for diabetic patients, we organized the multidisciplinary care team. During 5 months, 31 diabetic inpatients were applied the critical pathway and the results were compared with 11 diabetic inpatients who were treated with conventional way. We assessed the patients satisfaction, knowledge on the disease, compliance of medical regimen, length of stay(LOS) and hospital cost. We used the computer program SAS for statistical analysis. Data were summarized with mean, and analyzed using t-test repeated measures ANOVA and Wilcoxon rank sum test. Results : Length of stay(LOS) was remarkably shortened in critical pathway group compared with the conventional treatment group(7.6±1.23 vs 12.0±4.73, p<0.000). Although LOS was significantly shortened in critical pathway group, patients satisfaction was much higher than conventional treatment group. There were no significant difference of knowledge on the disease, compliance of medical regimen and blood glucose level between two groups at discharge. Hospital cost of each patients also significantly decreased in critical pathway group(890,000 won vs 1,280,000 won, p<0.05). Conclusion : These results showed that establishment of critical pathway for diabetic inpatients with team approach is the one of the way to improve the quality of diabetic patients management and to enhance the efficiency of hospital management.