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EMI filter의 감쇄 성능 예측을 위한 소자의 공통 및 차동 모드 모델링 기법
김희승,백미란,원도현,홍성수,노정욱,한상규,원재선,오동성 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.7
EMI 감쇄성능의 정확한 예측을 위해서는 EMI 필터에 사용되는 소자에 대한 명확한 공통 및 차동 모드 임피던스 모델 정보가 필요하다. 하지만 기존의 전도성 EMI 감쇄성능 예측 방식은 이러한 모델의 부재로 인해 고주파수에서 예측 값과 실험 결과에 큰 오차가 발생하는 문제점이 있다. 이를 해결하기 위해 본 논문에서는 일반적으로 사용되는 EMI 필터의 소자를 전도성 전파 규제 범위에서 모델링하고 이를 이용하여 공통 및 차동모드 임피던스로 다시 모델링한다. 실험 결과 EMI 감쇄성능을 1㎒ 이하의 영역에서만 예측할 수 있었던 기존 방식과 비교해 제안 방식은 10㎒ 영역까지 예측할 수 있는 장점이 있다. 최종적으로 임피던스 분석기를 이용한 측정 결과와 모의실험 결과를 제시하여 제안 방식의 타당성 및 유용성을 검증한다.
Impact of Chemoradiation on Prognosis in Stage IVB Cervical Cancer with Distant Lymphatic Metastasis
김희승,김태헌,이응석,김학재,정현훈,김재원,송용상,박노현 대한암학회 2013 Cancer Research and Treatment Vol.45 No.3
Purpose The purpose of this study was to determine whether chemoradiation (CCR) is efficient for improving prognosis, compared with systemic chemotherapy (SC), in patients with stage IVB cervical cancer who have distant lymphatic metastasis. Materials and Methods Among 2,322 patients with cervical cancer between January 2000 and March 2010,43 patients (1.9%) had stage IVB disease. After exclusion of 19 patients due to insufficient data and hematogenous metastasis, 24 patients (1%) who received CCR (n=10) or SC (n=14) were enrolled. We compared tumor response, progression-free survival (PFS) and overall survival (OS), and disease recurrence between CCR and SC. Results Complete response rates were 60% and 0% after CCR and SC (p<0.01). Grade 3 or 4 leukopenia was more common in patients treated with CCR (24.4% vs. 9.1%,p=0.03), whereas grade 3 or 4 neuropenia was more frequent in those treated with SC (28.4% vs. 11.1%, p=0.03). Development of grade 3 proctitis occurred as a late radiotherapy (RT)-related toxicity in only one patient (10%) treated with CCR. In addition,squamous cell carcinoma and CCR were favorable prognostic factors for improvement of PFS (adjusted hazard ratios [HRs], 0.17 and 0.12; 95% confidence intervals [CIs], 0.04 to 0.80 and 0.03 to 0.61), and only CCR was significant for improvement of OS (adjusted HR, 0.15; 95% CI, 0.02 to 0.90). However, no differences in the rate and pattern of disease recurrence were observed between CCR and SC. Conclusion CCR may be more effective than SC for improving survival, and can be regarded as a feasible method with some caution regarding late RT-related toxicity for treatment of stage IVB cervical cancer with distant lymphatic metastasis.
Conventional versus nerve-sparing radical surgery for cervical cancer: a meta-analysis
김희승,김기원,Seung-Bum Ryoo,서정화,김상윤,Ji-Won Park,Min-A Kim,Kyoung Sup Hong,정창욱,송용상 대한부인종양학회 2015 Journal of Gynecologic Oncology Vol.26 No.2
Objective: Although nerve-sparing radical surgery (NSRS) is an emerging technique for reducing surgery-related dysfunctions,its efficacy is controversial in patients with cervical cancer. Thus, we performed a meta-analysis to compare clinical outcomes,and urinary, anorectal, and sexual dysfunctions between conventional radical surgery (CRS) and NSRS. Methods: After searching PubMed, Embase, and the Cochrane Library, two randomized controlled trials, seven prospective andeleven retrospective cohort studies were included with 2,253 patients from January 2000 to February 2014. We performed crudeanalyses and then conducted subgroup analyses according to study design, quality of study, surgical approach, radicality, andadjustment for potential confounding factors. Results: Crude analyses showed decreases in blood loss, hospital stay, frequency of intraoperative complications, length of theresected vagina, duration of postoperative catheterization (DPC), urinary frequency, and abnormal sensation in NSRS, whereasthere were no significant differences in other clinical parameters and dysfunctions between CRS and NSRS. In subgroupanalyses, operative time was longer (standardized difference in means, 0.948; 95% confidence interval [CI], 0.642 to 1.253), whileintraoperative complications were less common (odds ratio, 0.147; 95% CI, 0.035 to 0.621) in NSRS. Furthermore, subgroupanalyses showed that DPC was shorter, urinary incontinence or frequency, and constipation were less frequent in NSRS withoutadverse effects on survival and sexual functions. Conclusion: NSRS may not affect prognosis and sexual dysfunctions in patients with cervical cancer, whereas it may decreaseintraoperative complications, and urinary and anorectal dysfunctions despite long operative time and short length of theresected vagina when compared with CRS.
고혈압을 동반한 제2형 당뇨병 환자에서의 creatinine과 미세 단백뇨 증가
김희승,송민선,유양숙 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.2
The purpose of this study was to identify clinical characteristics of type 2 diabetic patients with hypertension. The subjects were 209 type 2 diabetic patients who visited at the endocrine center at Kangnam St. Mary's Hospital of Catholic University in Seoul from beginning of March through the end of April in 2001. The patients' clinical laboratory data were assessed at medical record review. The data were analyzed using for t-test, x² test. The results were as follows : 1) There were no significant differences in age, body mass index, sex, family history of diabetes and oral hypoglycemic agents between hypertensive group and normotensive group. However, percentage of patients receiving insulin treatment was higher significantly in the hypertensive group. 2) Creatinine and microalbuminuria levels were higher significantly in the hypertensive group. However, fasting blood glucose levels were lower significantly in the hypertensive group. There were no significant differences in HbA_(1C), 2-hour postprandial blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol, lipoprotein(a) and blood urea nitrogen between two groups. Our present study supports that Creatinine and microalbuminuria levels were higher significantly in the hypertensive group.