그룹운동 프로그램이 여자 청소년들의 체력과 정신신경면역계에 미치는 영향

변정은(Byun Jung Eun),구정훈(Koo Jung Hoon) 한국발육발달학회 2018 한국발육발달학회지 Vol.26 No.4

The purpose of this study was to investigate the effects of group exercise on physical fitness and psychoneuroimmunological factors in female adolescents. Thirty-three female adolescents were divided into three groups, control (CON; n = 11), running exercise (RE; n = 11), and group exercise (GX; n = 11) for 12 weeks of the exercise intervention. For all subjects, measurements of body composition, cardiovascular function, psychological factors, and serum neuroimmunological factors were completed before and after the 12-week intervention. First, the changes in mental stress were significantly lower in RE and GX compared with the CON group, and it was significantly decreased following the exercise intervention in RE and GX groups. Although there was no significant difference in the level of change between groups in depression and self-confidence, it was only reduced following GX intervention in GX group. The changes in peak oxygen uptake and exercise time were significantly greater in the RE and GX compared to the CON group, and it was increased after exercise intervention in RE and GX groups. The changes in percentage of body fat(BF%) were significantly lower in the GX compared to the CON group. The changes in lean body mass(LBM) were significantly greater in RE and GX compared to the CON group. Moreover, BF% was decreased whereas LBM was increased in the GX group after the exercise intervention. Finally, the changes in tumor necrosis factor alpha were only reduced in the RE group, resulting in significantly lower changes compared with CON and GX groups. More interestingly, although no significant differences were found between groups, brain-derived neurotrophic factor(BDNF) was increased following the exercise intervention in the GX group only. These findings demonstrate that GX will result in decreased BF% and increased LBM, and cardiovascular function. In addition, GX significantly decreases stress, and depression, but increases self-confidence and BDNF. Collectively, this indicates that 12 weeks of GX intervention can have a positive effect on body composition, physical fitness, and neurological function, which may contribute to improvements in psychological factors in female adolescents.

폴록사머-폴리아크릴산 IPNs의 약물 조절 방출

변은정(Eun Jung Byun),박주애(Joo Ae Park),이승진(Seung Jin Lee),김길수(Kil Soo Kim) 대한약학회 1997 약학회지 Vol.41 No.1

Poloxamer-poly (acrylic acid) (PAA) interpenetrating polymer networks (IPNs) were prepared via matrix polymerization of acrylic acid with poloxamer prepolymer. The equilibrium swelling of poloxamer/PAA IPNs was determined in various pH medium. The swelling of poloxamer/PAA IPNs was more affected by pH difference compared with the swelling of homo PAA gel due to protonation and deprotonation of the PAA network, followed by reversible formation and dissociation of the interpolymer complex due to hydrogen bonding between acidic hydrogens and ether oxygens. Nonionic/anionic/cationic drugs were incorporated into IPN matriceds as a model drug and their release behavior was studied. Nonionic, drug revealed release patterns depending solely on pH dependent swelling kinetics. In contrast, the release of ionic drugs was significantly affected by ionic drug-polymer interaction as well as the swelling kinetics.

Group Exercise 프로그램에 참여한 중년 여성의 운동중독, 신체적 자기효능감, 생활만족의 인과관계

변정은(Jung Eun Byun),정희정(Hee Jung Jung),이준우(Jun Woo Lee) 한국여가레크리에이션학회 2010 한국여가레크리에이션학회지 Vol.34 No.3

Purpose of this study is to analyze the causality among exercise addiction, physical self-efficacy, and life satisfaction through the middle aged women participated in GX Program. For this study, the data of 284 was collected from middle aged women participated in GX program at the sports center in Seoul and Kyeonggi province and analyzed with SPSS 15.0 and AMOS 7.0 program. he results of this study were as follows: First, the middle aged women participants` exercise addiction form GX program had a positive influence on the physical self-efficacy, and life satisfaction. Second, the middle aged women participants` physical self-efficacy from GX program had a positive influence on the life satisfaction. In conclusion, the causality was established from the structure of research model.

피부과 영역에서의 전기수술의 원리와 임상적 사용에 대한 고찰

변은정 ( Eun Jung Byun ),조성빈 ( Sung Bin Cho ),김혜성 ( Hei Sung Kim ) 대한피부과학회 2016 대한피부과학회지 Vol.54 No.7

The term electrosurgery refers to the passage of high-frequency alternating electrical current through the tissue, to achieve a specific surgical effect. It is used in everyday dermatologic practice for various purposes, including tissue dissection, bleeding control, and the removal of common skin lesions such as viral warts, melanocytic nevi, and cherry angiomas. Considering the nature of the device, adverse effects including skin burn and scarring can occur at any stage of the procedure. Therefore, it is essential that electrosurgery be performed by skilled and well-trained physicians. In this paper, we introduce a brief history of electrosurgery and present its categories and their clinical uses. In addition, the possible adverse effects and safety measures of electrosurgery are addressed. (Korean J Dermatol 2016;54(7):503∼508)

그룹운동 프로그램의 참여중지가 여자 청소년의 신체구성, 심폐체력 그리고 정신신경면역계에 미치는 영향

변정은 ( Byun Jung-eun ),구정훈 ( Gu Jung-hoon ),강은범 ( Kang Eun-bum ) 한국체육대학교 체육과학연구소 2019 스포츠사이언스 Vol.36 No.2

본 연구는 그룹운동 참여중지가 여자 청소년들의 신체구성, 체력 및 정신신경면역계에 미치는 영향을 확인하는데 목적이 있다. 집단은 통제 집단(Control: CON, n=11), 런닝운동 집단(Running exercise: RE, n=11), 및 그룹운동 집단(Group exercise: GX, n=11)으로 구분하여 총 33명의 자료를 분석에 이용하였다. 모든 대상은 운동중지 전과 후에 신체구성, 심폐기능, 정신지표 및 혈청 신경면역학적 요인을 분석하였다. 그 결과, 최대산소섭취량과 운동시간에서 RE 집단과 GX 집단 모두 운동중지 전(post)에 비해 운동중지(detraining) 후에 통계적으로 유의하게 감소하였으나, 최대심박수는 유의한 차이가 나타나지 않았다. 혈액지표에서 BDNF는 RE 집단과 GX 집단 모두 운동중지 전에 비해 운동중지 후에 통계적으로 유의하게 감소하였으며, IL-6, MCP-1, TNF-α는 유의한 차이가 나타나지 않았다. 신체구성(몸무게, 체지방률과 BMI)과 정신지표(stress, depression and self-confidence)에서는 유의한 차이가 나타나지 않았다. 종합적으로 4주간의 운동중지는 여자 청소년의 심페기능과 BDNF에 부정적인 영향을 미치는 것으로 나타났다. 추후 운동프로그램 참여 기간과 운동중지 기간에 따른 좀 더 구체적인 연구가 진행된다면, 청소년들의 가장 적절한 운동훈련 기간과 운동중지 기간을 밝혀내어 신체적 건강 및 정신신경면역학적 건강에 효과적인 최적의 운동 프로그램을 제시할 수 있을 것으로 생각된다. The purpose of this study was to investigate the effects of group exercise and detraining on body composition, cardiorespiratory fitness and psychoneuroimmunological factors in female adolescents. Thirty-three female adolescents were divided into three groups, control (CON; n = 11), running exercise (RE; n = 11), and group exercise (GX; n = 11) and these were used for the analysis. For all subjects, measurements of body composition, cardiorespiratory fitness, psychoneuroimmunological factors, and serum neuroimmunological factors were completed before and after detraining. First, the changes in maximal oxygen uptake and exercise duration were significantly lower in RE and GX compared with the CON group, and it was significantly decreased after detraining than before detraining, but maximum heart rate was no significant difference in the level of change between groups. The change of serum n BDNF was significantly lower in RE and GX compared with the CON group, but IL-6, MCP-1, TNF-α were no significant difference in the level of change between groups. Finally, body composition(body weight, percentage of body fat, BMI) and mental stress(stress, depression and self-confidence) were no significant difference in the level of change between groups. Collectively, this indicates that 4 weeks of detraining can have negative effect on the cardiorespiratory fitness and BDNF in female adolescents. If more specific studies were conducted according to the participation period and detraining period of the exercise program, the most appropriate exercise duration period and the period of detraining will be revealed which may contribute to be provide the optimal exercise program effective for physical health and psychoneuroimmunological for the female adolescents.

인터벌 웨이트 훈련이 조정선수들의 로윙 2000m 구간별 생리적 변인과 운동수행력에 미치는 영향

변원태(Byun Won-Tae),변정은(Byun Jung-Eun),박영식(Park Young-sik),차정훈(Cha Jung-Hoon),염동철(Yeom Dong-Chul),박수연(Park Soo-Yeon),나승희(Nha Seung-Hee),조준용(Cho Joon-Yong),조인호(Cho In-Ho) 한국코칭능력개발원 2010 코칭능력개발지 Vol.12 No.2

Helicobacter pylori 감염과 대장 신생물 발생의 관련성

홍은정 ( Eun Jung Hong ),박동일 ( Dong Il Park ),손희정 ( Hee Jung Sohn ),배문희 ( Mun Hee Bae ),김화목 ( Hwa Mock Kim ),김용성 ( Yong Sung Kim ),변선정 ( Sun Jeong Byun ),박정호 ( Jung Ho Park ),김홍주 ( Hong Joo Kim ),조용균 ( Y 대한내과학회 2008 대한내과학회지 Vol.74 No.6

목적: Helicobacter pylori 감염은 만성 위염, 소화성 궤양 뿐 아니라 위암의 원인으로도 알려져 있다. 최근 대장암과 H. pylori 감염과의 연관성에 대한 연구결과들이 발표되면서 이에 대한 관심도 높아지고 있는 실정으로 아직까지는 서로 상반된 의견이 공존하고 있다. 이에 H. pylori 감염률이 높은 한국인에서 H. pylori 감염과 대장의 신생물 발생과의 관련이 있는지 알아보고자 하였다. 방법: 2004년 1월부터 2005년 11월까지 강북삼성병원과 삼성서울병원에서 건강검진을 받은 수진자 중 대장내시경과 H. pylori 혈청 항체검사를 동시에 받은 1,590명을 대상으로 후향적 연구를 시행하였다. 대상자들 모두. H. pylori 양성군과 음성군으로 분류하여 각각 대장용종과 대장암의 발생빈도를 비교하였다. 결과: 1,590명의 대상자 중에서 남자는 1,297명, 여자는 293명이었으며 이들의 평균 나이는 49.9세로 남자는 50세, 여자는 49세였다. H. pylori 혈청 검사 양성인 군은 893명으로 H. pylori 감염 빈도는 56.2%이었고, 남자에서는 56.1%, 여자에서는 56.3이었다. H. pylori 감염 여부에 따른 대장 용종의 발생률은 두 군에서 의미있는 차이를 보이지 않았다. 결론: H. pylori 감염과 대장 용종 발생과는 상관관계가 없는 것으로 보인다. Background/Aims: Helicobacter pylori infection is a recognized cause of chronic gastritis, peptic ulcer and gastric adenocarcinoma. However, both positive and negative associations with colorectal neoplasia have been reported. The aim of this study was to determine whether H. pylori infection is associated with an increased risk of colonic neoplasia in a Korean population. Methods: We examined 1,590 subjects (1,297 men and 293 women) who underwent colonoscopy and serologic testing for IgG antibodies against H. pylori at the Health promotion Center in Kangbuk Samsung Hospital and at Samsung Medical Center. We compared the prevalence of colonic neoplasia in the seropositive subjects with that of the seronegative subjects. Results: The overall prevalence of H. pylori in our study population was 56.2%. There were no significant differences of the baseline characteristics between the two groups. There was no statistically significant difference in the prevalence of colonic neoplasia between the seropositive group and the seronegative group (p=0.090). Conclusions: These findings suggest that there is no significant association between H. pylori infection and colonic neoplasia.(Korean J Med 74:605-610, 2008)

사회적 환경을 포함한 서비스스케이프가 고객의 감정반응과 행동의도에 미치는 영향

변광인(Gwang In Byun),이정은(Jung Eun Lee),김기진(Gi Jin Kim) 한국호텔외식관광경영학회 2014 호텔경영학연구 Vol.23 No.1

The purpose of this study is finding out the impact of servicescape including social environment such as coffee shop employees and other customers, which is differentiated from other studies, on emotional responses and behavioral intention of customers in coffee shop environment. The revenues of brand coffee shops were compared and top four revenue brands(Starbucks, Caffebene, Coffee Bean and Angel-in-us) were selected. Questionnaire survey on customers who visited Starbucks, Caffebene, Coffee Bean and Angel-in-us located in Daegu city-center from June 24th to 29th 2013 were conducted. The survey consists of 100 questionnaire sheets per each brand. 384 questionnaire answer sheets were used for final analysis after excluding insincere answer sheets. According to the result of final analysis, esthetic aspect, comfort aspect, visible aspect of other customers and image of employees have significant positive impacts on pleasure while convenience and visible aspect of other customers have significant positive impacts on arousal. In addition, comfort aspect and image of employees have significant impacts on behavioral intention while pleasure and arousal both have significant impacts on behavioral intention.

CaSki 세포주에 대한 비소화합물의 세포 성장 억제 및 세포자멸사

변정미 ( Jung Mi Byun ),정대훈 ( Dae Hoon Jeong ),이대심 ( Dae Sim Lee ),김주란 ( Joo Ran Kim ),김영남 ( Young Nam Kim ),정은정 ( Eun Jeong Jeong ),성문수 ( Moon Su Sung ),이경복 ( Kyoung Bok Lee ),김기태 ( Ki Tae Kim ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.7

목적: Paclitaxel, cisplatin, 삼산화비소, 육산화사비소를 단독 혹은 병합 투여하여 CaSki 자궁경부암 세포주에 대한 성장 억제와 세포자멸사를 비교해 보고자 하였다. 연구 방법: 약물 농도 및 시간에 따른 세포 성장 억제 정도를 각 약물을 투여한 후 water-soluble tetrazolium salts (WSTs) -1 assay로 측정하여 비교하였다. 각 약물을 단독 혹은 병합 투여한 후 세포를 annexin V/PI 염색한 후 그 정도를 흐름 유세포 분석기를 이용하여 세포자멸사 정도를 분석하였다. 결과: Paclitaxel, cisplatin, 삼산화비소, 육산화사비소는 농도와 처리 시간에 의존적으로 CaSki 세포성장을 억제하였다. 특히, 육산화사비소는 삼산화비소보다 세포성장을 더 많이 억제시켰다. Paclitaxel, cisplatin, 삼산화비소와 육산화사비소는 시간이 지남에 따라 세포자멸사를 진행시켰다. Cisplatin과 육산화사비소를 병용 투여한 군에서 다른 병용 투여군보다 세포자멸사가 더 많이 진행하였다. 결론: 육산화사비소는 CaSki 자궁경부암 세포주에 대해 다른 제제보다 더 강력한 항종양 효과를 나타내었다. 임상시험을 통해 육산화사비소의 항종양효과에 대한 더 많은 연구가 필요할 것으로 생각된다. Objective: To compare inhibition of cell growth and apoptosis in human cervical cancer cell lines (CaSki) by paclitaxel, cisplatin, arsenic trioxide and tetraarsenic oxide. Methods: Inhibition of cell growth was determined by the water-soluble tetrazolium salts (WSTs) -1 assay. For apoptosis analysis in CaSki cell line treated with single or combination of two agents, CaSki cell line treated with each agent was stained with annexin-V/PI and flow cytometry was performed. Results: Progression of apoptosis in CaSki cell line treated with paclitaxel, cisplatin, arsenic trioxide, and tetraarsenic oxide was time dependent. Inhibition of cell growth in CaSki cell line by paclitaxel, cisplatin, arsenic trioxide, and tetraarsenic oxide was dose and time dependent. Especially, tetraarsenic oxide was more effective in inhibition of CaSki cell growth compared to arsenic trioxide. Group treated with combination of cisplatin and tetraarsenic oxide showed more progressive apoptosis compared to other combination group. Conclusion: Tetraarsenic oxide has more potent anti-tumor effects than other agents on CaSki cell line. We need to consider further study about antitumor effect of tetraarsenic oxide through clinical study.

TMS320C40을 이용한 3상 PWM AC/DC 컨버터 제어

변영복(Young-Bok Byun),김은수(Eun-Soo Kim),구헌희(Heun-Hoi Koo),조기연(Kee-Yeon Joe),박성준(Sung-Jung Park),김철우(Cheul-U Kim) 대한전기학회 1996 대한전기학회 학술대회 논문집 Vol.1996 No.7