Preparation of Helium Isotope-certified Reference Materials by Gravimetry

James Tshilongo,민들래,이진복,김진석 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.2

An advanced gravimetric system was used to produce certified reference materials of mixtures of helium isotopes, traceable to the Système International d'Unitès (SI unit) of moles. Critical factors in developing isotope reference mixtures include the purity assessment of the source gases before preparation, the weighing system used for gravimetric mixing, a well-developed gas filling system, and internal consistency among the mixtures. Three artificial helium isotope reference mixtures were prepared with absolute isotope ratios, R(4He/ 3He), of 18.905 ± 0.036, 98.78 ± 0.21, and 209.82 ± 0.44 (k = 1), respectively. The internal consistency between the mixtures was verified using a precision single-focusing magnetic sector-type mass spectrometer with a dynamic inlet system. The results showed that the proportions of the three reference isotope mixtures were well within the measurement uncertainty. The isotope reference mixtures were produced with the highest metrological uncertainty level.

간호대학생의 환자안전 역량에 영향을 미치는 요인

민들레,곽은주,박승미 한국간호교육학회 2022 한국간호교육학회지 Vol.28 No.3

Purpose: The purpose of this study is to identify nursing students' level of critical thinking disposition, communication skills, and self-leadership and to identify factors that affect the patient safety competency of nursing students. Methods: This study employs a descriptive research, method and was conducted from April 20 to May 19, 2022, with students from three nursing colleges in Korea. The collected data were analyzed by frequency and percentage, independent t-test, Pearson's correlation coefficients, and multiple regression. All analyzes were conducted using IBM SPSS 22.0. Results: The results of the multiple regression analysis showed that the regression model was significant (F=17.30, p<.001) and that communication skills (β=.22, p=.001), self-leadership (β=.31, p<.001), patient safety education experience (β=.15, p=.009), and subjects for credit (β=.15, p=.006) explained 28.0% of nursing students' patient safety competency. Conclusion: It is necessary to develop a self-leadership and communication skills improvement program and to organize rgular courses safety education subjects to improve the patient safety competency of nursing students.

반응표면분석법을 이용한 대추잎 항산화물질의 에탄올추출조건 최적화

민들레(Dul-Lae Min),임석원(Seokwon Lim),안준배(Jun-Bae Ahn),최영진(Young Jin Choi) 한국식품과학회 2010 한국식품과학회지 Vol.42 No.6

대추잎 항산화 물질의 고효율 추출을 위한 에탄올 용매추출조건을 반응표면분석법을 사용하여 최적화하였다. Box-Behnken design에 따라 추출공정 조작변수(온도, 시간, 에탄올 농도)를 독립변수로, 이에 따라 영향을 받는 종속변수(총 폴리페놀 함량, 총 플라보노이드 함량, 전자공여능)를 설정하여 실험하였다. 추출물의 총 폴리페놀 함량과 총 플라보노이드 함량은 시간과 온도의 영향을 거의 받지 않으며, 용매비가 높을수록 증가하다가 최고점을 보인 후 다시 감소하는 경향을 나타내었다. 전자공여능 또한 시간과 온도의 영향보다는 용매비에 영향을 많이 받는데, 에탄올 농도가 높을수록 전자공여능이 높게 측정되었다. 추출물의 특성을 모두 만족시키는 최적 추출조건 범위 내에서 임의의 조작조건(온도 45℃, 시간 15분, 에탄올 농도 45%)을 설정하였다. 최적조건에서 예측값과 실험값을 비교한 결과, 유사한 값을 보여주어 회귀식이 신뢰할 수 있음을 알 수 있었다. The leaves of Zizyphus jujuba have been used for various purposes including medicine and nutrition. In this study, the conditions for the ethanol extraction of antioxidant from Zizyphus jujuba were optimized using response surface methodology (RSM). A Box-Behnken design containing 15 experimental runs with three replicates was employed to study the effects of solvent extraction conditions such as extraction temperature (℃, X<SUB>1</SUB>), extraction time (min, X<SUB>2</SUB>), and ethanol concentration (%, X<SUB>3</SUB>) on the extraction yield of antioxidants from Zizyphus jujuba. The yields of total polyphenols and total flavonoid, and electron donating activity (EDA) were considered as response variables. The second-order polynomial model gave a satisfactory description of the experimental results showing different patterns of extraction conditions with variation in the linear, quadratic, and interaction effects of the independent variables. Based on four-dimensional RSM, one of the optimized sets of conditions was 45% ethanol, 45℃, and an extraction time of 15 min. Under the optimal conditions, the predicted values were 177.64 mg/g dry basis, 35.99 mg/g dry basis, and 86.14% Vit.C equivalents for total polyphenols, total flavonoids, and EDA, respectively. The experimental values showed good agreements with the predicted values.

甘松香 (감송향)이 아토피樣 (양) 피부염에 미치는 영향

민들레,박은정,Min, Deul-Le,Park, Eun-Jung 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.2

Objectives NJ is being used to treat inflammatory diseases in Korea. In this study, we attempted to evaluate the effects of NJ on atopic dermatitis (AD)-like lesions and mast cell-mediated allergy inflammation in vivo and in vitro. Methods and Results We investigated to ascertain the pharmacological effects of NJ on 2,4-dinitrofluorobenzene (DNFB)-induced allergic reactions under in vivo conditions. Additionally, to find possible explanations for the anti-inflammatory mechanisms of NJ, we evaluated the regulatory effects of NJ on the level of inflammatory mediators in phorbol 12-myristate 13-acetate plus calcium ionophore A23187 (PMACI)-stimulated human mast cells (HMC-1). Conclusions NJ inhibited the production of the inflammatory cytokines (IgE, IL-6, IL-8 and TNF-${\alpha}$) significantly in vivo and in vitro.

쇼핑몰 통행공간의 실내디자인 요소에 관한 연구

민들레(Min, Deul re),김경숙(Kim, Kyung sook) 한국디지털디자인협의회 2006 (사)한국디지털디자인협의회 conference Vol.2006 No.5

교부와 여성

민들레 한영신학대학교 출판부 2009 한영연구논문 Vol.1 No.

한국 사회에서 좋은 죽음에 대한 개념분석

민들레,조은희 한국노인간호학회 2017 노인간호학회지 Vol.19 No.1

Purpose: The purpose of this study was to define the meaning of a good death mentioned in Korean culture. Methods: This study was carried out using Rodgers' evolutionary concept analysis strategy. A review of the literature was done with key words related to good death and other relevant words in literature published in English or Korean. The literature search was conducted from 1995 to 2016 for overseas and from 2000 to 2016 for domestic. The final selection target was 44 pieces. Each document was divided into 7 disciplines, including 25 domestic documents. Results: Three dimensions and seven attributes were identified; 1) The preparation stage for death: living well, preparation for dying, 2) The final stage of death: avoiding meaningless extension of life, dignity, comfort and interaction with healthcare providers, 3) The post death stage: positive feeling of families. Antecedent to good death were dying persons, families and healthcare providers' wishes for good death, The consequences were their experience during the period of dying and feeling after dying. Conclusion: There was a change in the concept of good death according to the times. It is important for nurses to understand the concept of good death in order to provide care with good quality to patients who are faced with death, their families and healthcare providers.

Predictors of Quality of Life among Grandparents Raising Their Grandchildren: An Ecological Approach

민들레,김수희 한국지역사회간호학회 2017 지역사회간호학회지 Vol.28 No.1

Purpose: The purpose of this study is to examine factors affecting quality of life among grandparents raising their grandchildren. Methods: This study carried out a secondary analysis of data from the 2014 Korean Longitudinal Study of Aging (KLoSA) and Statistics Korea. Data collected from 224 grandparents who reported raising their grandchildren were analyzed using descriptive statistics, independent t-test, ANOVA, pearson correlation coefficient, and multilevel regression analysis. Results: The mean score of the participants’ quality of life was 62.63. Significant predictors of quality of life of the grandparents included subjective health status, last year’s total house income, number of last year’s travels, frequency of last year’s movie seeing, and number of children's parks per 100,000 population. Conclusion: These results suggest that public health nurses in improving quality of life of grandparents focus on children's parks and formal social supports as community factors as well as regular exercise as an individual factor in order to be more effective.

당귀음자가감방(當歸飮子加減方)과 외치법(外治法)을 병용한 소아(小兒) 건선(乾癬) 치험 1례

민들레,장성진,박은정,Min, Deul-Le,Chang, Sung-Jin,Park, Eun-Jung 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.3

Objectives The purpose of this case study is to report the effect of concurrent administration of Danguieumja-gagambang and external treatments on childhood psoriasis. Methods The subject is a child with psoriasis. This patient was treated with oriental herbal medicine (Danguieumjagagambang) and external treatments. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results After the treatment, the symptoms of psoriasis were relieved. PASI score of this child went down from 4.7 to 0. Conclusions This study showed that concurrent administration of Danguieumja-gagambang and external treatments can be an effective choice for psoriasis.

영유아 아토피피부염 환자 69명의 한의학적 치료효과에 대한 후향적 연구

민들레,한명화,박건,서산,한수련,Min, Deul Le,Han, Myeong Hwa,Park, Gun,Seo, San,Han, Su Ryun 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.3

Objectives The purpose of this study is to report the effectiveness of Korean medicine treatment on 69 infant and young child atopic dermatitis patients. Methods 69 infants and young child atopic dermatitis patients who had visited oriental medical clinics from 2011.1.9 to 2012.1.31 were studied. All of them were continually treated for 3 to 9 months, and were analyzed by Objective SCORAD Index (OSI). A detailed analysis of OSI was done according to gender, age, using of topical steroid ointment, family history of atopic disease, treatment period, and intensity. Results 1. Male and female percentage of the study group was 56.5%: 43.5%. The average period of treatment was 6.09 months. 71.0% used topical steroid ointment, and 65.2% had family history of atopic disease. 2. The average period of treatment was significantly longer in patients who used topical steroid ointment, or who had family history of atopic disease. 3. 95.7% of total patients reported decrease in OSI score at the final visit. OSI was significantly lowered after 3, 6, and 9 months of treatment. The longer period of treatment, the lower average post-treatment OSI. 4. 85.5% of the study group had severe dermatitis, and 14.5% was moderate case based on the OSI intensity assessment at initial visit. These percentages got changed at the final visit as 34.8% of severe, 58.0% of moderate, and 7.2% of mild cases. The average treatment period of patients who were diagnosed as severe at the initial visit was 6.18 months, and their final OSI improvement rate was 39.58%. 58% of them were improved to be mild or moderate at the final visit. Conclusion The Korean medicine treatment is effective in treating infant and young child atopic dermatitis patients. There was significant decrease in OSI score after 3, 6, and 9 months of treatment. The difference increase with the treatment period.