적외선 영상 처리를 통한 Formalin Test 통증 모델에서의 염전 침자극 효과에 대한 연구

류재관,이순걸,임성수,이재동,민병일,류운영,Ryu, Jae-kwan,Lee, Soon-geul,Rhim, Sung-soo,Lee, Jae-dong,Min, Byung-il,Ryu, Un-young 대한침구의학회 2004 대한침구의학회지 Vol.21 No.2

Objective: As a manual accupucture method, the twirling-needle treatment has been known more effective in relieving pain than the conventional simple accupuncture treatment. Finding a proper treatment condition is difficult because of the lack of a quantative measurement of the alleviation of pain made by acupuncture. In this research, the authors propose the use of infrared thermal images in a formalin test to quantatively verify the effect of twirling. Methods: After injecting 10%~20% formalin into the tail of rats, the infrared thermal images(ITI) have been obtained to estimate the thermal distribution caused by inflammation. The authors propose a processing method to measure the thermal distribution from the thermal images obtained from the infrared camera as a pain model of the formalin test. Results: The pain model obtained from the infrared thermal image has two phases. The first phase, which is a transient period, is the initial 20 minutes when the pain is developed after the formalin injection. The second phase, which is a steady state, is where the development of pain lasts for 60 minutes or more after the first stage. This characteristic of the proposed model based on ITI is consistent with that of the pain model reported by other researchers whose works are based on the time-course of flinching and licking/biting, following a different concentration of formalin. It is noticed that the response of the thermal distribution obtained from ITI shows very high correlation to the behavioral response in the formalin test performed by Kazuhiro Okuda and four others5). In addition, the authors propose an ITI method to determine the pain-reducing effect of the acupuncture. The thermal distribution obtained from the experiment shows that there is significant pain reducing effect made by the twirling-needle method.

아이디어 연상기억 탐색 (SIAM) 모형에 기반한 비즈니스 문제해결 창의성 측정을 위한 뉴로과학 관점의 탐색연구

류재관(Jae Kwan Ryu),이건창(Kun Chang Lee) 한국경영학회 2018 經營學硏究 Vol.47 No.5

This study aims to propose a novel method of measuring the BPSC (Business Problem-Solving Creativity) from the neuroscience perspective of fNIRS (functional near-infrared spectroscopy). Neuroscience literature shows that there exist very few studies on the BPSC itself which is known to specifically activate frontal cortex areas of human brain. From the view of this, we know that it is necessary to use a specific neuroscience approach focusing on the analysis of blood hemodynamic changes in the frontal cortex areas. To fill the research void like this, this study adopts fNIRS method to measure the changes of blood hemodynamic level occurring in the frontal cortex areas when users are solving the business problem-solving tasks. To enhance rigor, the experiment settings are designed to include (1) positive-negative emotion induction by music, (2) near-stimuli, far-stimuli based on SIAM (Search for Ideas Associative Memory) model, and (3) business problem-solving method by using cognitive map. Experimental results obtained from 28 qualified participants reveal that (1) the BPSC level changes signifcantly with positive and negative emotion, and (2) statistically significant activations are found in Brodmann 9, 10, 45, 46 areas in the frontal cortex, depending on the near-stimuli and far-stimuli.

기능적 근적외 분광법(fNIRS) 기반의 비즈니스 문제해결 창의성에 관한 탐색연구

류재관(Jae Kwan Ryu),이건창(Kun Chang Lee) 한국콘텐츠학회 2018 한국콘텐츠학회 종합학술대회 논문집 Vol.2018 No.5

정렬된 탄소나노튜브 복합체의 압전저항특성 및 기계적 특성 연구

김현우(Hyunwoo Kim),홍순국(Soon-Kook Hong),류재관(Jae-Kwan Ryu),박성훈(Sung-Hoon Park) 한국자동차공학회 2020 한국자동차공학회 학술대회 및 전시회 Vol.2020 No.11

무인수상정의 장애물 회피를 위한 3차원 라이다 기반 VFH 알고리즘 연구

원인식(Ihn-Sik Weon),이순걸(Soon-Geul Lee),류재관(Jae-Kwan Ryu) 인문사회과학기술융합학회 2018 예술인문사회융합멀티미디어논문지 Vol.8 No.3

In this paper, we use 3-D LIDAR for obstacle detection and avoidance maneuver for autonomous unmanned operation. It is aimed to avoid obstacle avoidance in unmanned water under marine condition using only single sensor. 3D lidar uses Quanergy s M8 sensor to collect surrounding obstacle data and includes layer information and intensity information in obstacle information. The collected data is converted into a three-dimensional Cartesian coordinate system, which is then mapped to a two-dimensional coordinate system. The data including the obstacle information converted into the two-dimensional coordinate system includes noise data on the water surface. So, basically, the noise data generated regularly is defined by defining a hypothetical region of interest based on the assumption of unmanned water. The noise data generated thereafter are set to a threshold value in the histogram data calculated by the Vector Field Histogram, And the noise data is removed in proportion to the amount of noise. Using the removed data, the relative object was searched according to the unmanned averaging motion, and the density map of the data was made while keeping one cell on the virtual grid map. A polar histogram was generated for the generated obstacle map, and the avoidance direction was selected using the boundary value. 본 논문은 무인수상정의 자율운항을 위한 장애물 탐지 및 회피기동을 위해 3차원 라이다를 사용하 였다. 단일센서만을 사용해서 해상조건에서의 무인수상정 장애물 회피운항을 하는데 목적이 있다. 3 차원 라이다는 Quanergy사의 M8센서를 사용하여 주변 환경 장애물 데이터를   로 수집하며 장애물 정보에는 Layer 정보와 Intensity 정보를 포함한다. 수집된 데이터를 3차원 직각좌표계로 변환 을 하고, 이를 2차원 좌표계로 사상한다. 2차원 좌표계로 변환한 장애물 정보를 포함하는 데이터는 수면위의 잡음데이터를 포함하고 있다. 그래서 기본적으로 무인수상정을 기준으로 가상의 관심영역을 정의하여서 규칙적으로 생성되는 잡음데이터에 대해서 삭제를 하였으며, 그 이후에 발생하는 잡음데 이터는 Vector Field Histogram으로 계산된 히스토그램 데이터에서 Threshold를 정해 밀도값에 비례 하여 잡음데이터를 제거하였다. 제거된 데이터를 이용하여 무인수상정의 움직임에 따른 상대물체를 탐색하여 가상의 격자지도에 1 Cell씩 저정하면서 데이터의 밀도 지도를 작성하였다. 작성된 장애물 지도를 폴라 히스토그램을 생성하고, 경계값을 이용하여 회피방향을 선정하였다.

Development of a Multi-Disk Type MR Fluid Brake with Modular Structure

김형래(Hyeong Rae Kim),이순걸(Soon-Geul Lee),박종덕(Jong Deok Park),김형(Hyung Kim),최명진(Myeong Jin Choi),류재관(Jae Kwan Ryu) Korean Society for Precision Engineering 2018 한국정밀공학회지 Vol.35 No.2

Recently the interest in miniaturization of mechanical devices has increased and magneto-rheological (MR) fluid brakes have been designed, fabricated and tested to be applied as a control element of various devices for assisting the elderly people. A multi-disk modular type of design is proposed to make an MR fluid brake that can generate high torque at the minimum size. The design parameters of the MR fluid brake were determined by mathematical modeling and the performance was predicted with magnetic analysis to maximize the design torque. A testbed was constructed and torque responses were measured and analyzed according to the input current for various rotational speeds to confirm the performance of the MR fluid brake. The experimental results showed that the MR fluid brake was applicable to actuating devices for assisting elderly people.

척골 지단 신경의 전기생리학적 연구

김종순,이현옥,안소윤,구봉오,남건우,김호봉,류재관,류재문 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

The ulnar nerve extends down the arm, across the elbow, and into the hand. It provides sensation to the little and ring fingers and activates many of the small muscles in the hand. The determination of peripheral nerve conduction velocity is an important part of ulnar nerve evaluation. The electrodiagnostic value as neurophysiologic investigative procedure has been known for many years but normal value of digital nerve was not reported in korea. The purpose of this investigation was to measure the digital nerve conduction velocity of ulnar nerve for obtain clinically useful reference value and compare difference in each fingers and then compare with the other countries. 71 normal Korean volunteers (age, 19-65 years; 142 hands) examined who has no history of peripheral neuropathy, diabetic mellitus, chronic renal failure, endocrinedisorders, anti-cancer medicine, anti-tubercle medicine, alcoholism, trauma, radiculopathy. Nicolet Viking Ⅱ(EMG machine) was use for detected conduction velocity and amplitude of digital nerve in ulnar nerve. Data analysis was performed using SPSS. Descriptive analysis was used for obtain mean and standard deviation and independent t-test was used to compare with ring and little finger. Conduction velocity of the right ring finger was 57.44m/sec and little finger was 55.32msec. The left ring finger was 55.55msec and little finger was 54.11msec. Amplitude of the right ring finger was 30.28µV and little finger was 48.36µV. The left ring finger was 30.67µV and little finger was 57.76µV. There were significantly difference between ring and little in amplitude (p<.05) but there were no statistically difference between conduction velocity of ring and little finger (p>.05). The amplitude of little finger are greater than ring finger. The present results revealed that electodiagnosis can easily perform in little finger for digital nerve of ulnar nerve study.

정중운동신경과 척골운동신경의 전기생리학적 연구

김종순,이현옥,안소윤,구봉오,남건우,김영직,김호봉,류재관,류재문 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

The determination of peripheral nerve conduction velocity is and important part to electrodiagnosis. Its value as neurophysiologic investigative procedure has been known for many years but normal value of median and ulnar motor nerve was poorly reported in Korea. To evaluate of median and ulnar motor nerve terminal latency, amplitude of CMAP(compound muscle action potential), conduction velocity and F-wave latency for obtain clinically useful reference value. 71 normal volunteers(age,19-65 years;142 hands) examined who has no history of peripheral neuropathy, diabetic mellitus, chronic renal failure, endocrine disorders, anti-cancer medicine, anti-tubercle medicine, alcoholism, trauma, radiculopathy. Nicolet Viking Ⅱ was use for detected terminal latency, amplitude of CMAP, conduction velocity and F-wave latency of median and ulnar motor nerve. Data analysis was performed using SPSS. Descriptive analysis was used for obtain mean and standard deviation, independent t-test was used to compare between Rt and Lt side also compare between different in genders. The results are summarized as follows: 1. Median motor nerve terminal latency was right 3.00ms, left 2.99ms and there was no significantly difference between right and left side and genders. 2. Median motor nerve amplitude of CMAP was right 17.26mV, left 17.50mV and there was no significantly differences between right and left side and genders. 3. Median motor nerve conduction velocity was right 57.89m/sec, left 58.03m/sec and there was no significantly difference between right and left side and genders. 4. Median motor nerve F-wave latency was right 25.74ms, left 25.59ms and there was significantly differences between genders. 5. Ulnar motor nerve terminal latency was right 2.38ms, left 2.45ms and there was significantly differences between right and left side. 6. Ulnar motor nerve amplitude of CMAP was right 15.99mV, left 16.02mV and there was no significantly differences between right and left side and genders. 7. Ulnar motor nerve conduction velocity was right 60.35m/sec, left 59.73/sec and there was no significantly differences between right and left side and genders. 8. Ulnar motor nerve F-wave latency was right 25.53ms, left 25.57ms and there was significantly differences between genders.