적층가공을 이용한 임시의치 제작 및 기존방식의 임시의치와의 비교 증례

김현아,임현필,강현,양홍서,박상원,윤귀덕,Kim, Hyun-Ah,Lim, Hyun-Pil,Kang, Hyeon,Yang, Hongso,Park, Sang-Won,Yun, Kwi-Dug 대한치과보철학회 2019 대한치과보철학회지 Vol.57 No.4

디지털치의학의 발달과 함께 computer-aided design and computer-aided manufacturing (CAD/CAM)을 이용한 3D 제작산업이 최근 급격한 성장을 하고 있다. 디지털 방식을 이용한 의치 제작 또한 최근의 디지털치의학 기술의 발전으로 증가하는 추세에 있다. CAD/CAM 제작방법은 크게 두가지 타입으로 나눌 수 있다: 절삭가공, 적층가공, 밀링과 같은 절삭가공은 블록 형태의 재료를 깎아 제조하는 기술을 토대로 하며, 3D printing과 같은 적층가공은 재료를 적층 방식으로 쌓아 올려 제조하는 기술을 토대로 한다. 적층가공은 밀링이 어려운 복잡한 구조의 제작에 적용할 수 있다. 본 증례에서, 적층가공방법이 레진상 총의치 제작에 이용되었다. 디지털방식을 적용한 의치의 사용기간동안 기능적, 심미적으로 만족할 만한 결과를 보여주었다. With development of digital dentistry, the 3-dimensional (3D) manufacturing industry using computer-aided design and computer-aided manufacturing (CAD/CAM) has grown dramatically in recent years. Denture fabrication using digital method is also increasing due to the recent development of digital technology in dentistry. The 3D manufacturing process can be categorized into 2 types: subtractive manufacturing (SM) and additive manufacturing (AM). SM, such as milling is based on cutting away from a solid block of materal. AM, such as 3D printing, is based on adding the material layer by layer. AM enables the fabrication of complex structures that are difficult to mill. In this case, additive manufacturing method was applied to the fabrication of the resin-based complete denture to a 80 year-old patient. During the follow-up periods, the denture using digital method has provided satisfactory results esthetically and functionally.

노인(老人) 내과환자(內科患者)의 임상통계적(臨床統計的) 고찰(考察)

김현아,정지천,이원철,Kim, Hyeon-Ah,Jeong, Ji-Cheon,Lee, Won-Chul 대한한방내과학회 1992 大韓韓方內科學會誌 Vol.13 No.1

Clinical observation was done on 496cases of the Out-patients and 136cases of the In-patients more than 65 years of age in Department of Internal Medicine, Oriental Medical Hospital in Dong Guk Univ. from March 1991 to February 1992. The results were as follows; 1. The ratio of senile (more than 65 years of age) was 16.4% in total Out-patients, was 38.1% in total In-patients. 2. The ratio of male to female was 1:1.1 in the Out-patients, In-patients was 1.2:1. The age distribution showed the large number in the 65-69 year group, the female more than the male in 70 th's group. 3. The diagnostic distribution was noted in the Out-patients as follows, Respiratory Dis. 50.6%, Cardiovascular Dis 16.4%, Brain Neurogic Dis. 14.5%, Gastrointestinal Dis. 8.1%. in the In-patients. Brain Neurogic Dis. was 76.5%, Cardiovascular Dis was 19.8%. 4. The ratio of the season distribution in the Out-patients was as follows, spring 40.2%, winter 21.2%, summer 20.9%, in the In-patients. winter was 35.9%, autumn was 25.0%, spring was 19.9%. 5. The utilization of therapeutic clinic before coming the Oriental Medical Hospital in Dong Guk Univ, was as follows, the ratio of the Out-patients was noted a hospital or clinic was 57.1%, no-treatment 22.9%, a oriental medical hospital or clinic was 8.3%. In the admission was noted no-treatment was 38.3%, a oriental medical hospital or clinic was 35.3%. 6. The ratio of the periods from onset to Out-patients department was noted within 5days was 7.3%, over 1 year was 52.6%. In the admission was noted within 1 day was 41.9%, within 7 days was 71.8%. 7. The ratio of the therapeutic periods in the Out-patients department was noted within 10 days was 48.3%, over 60 days was 7.1%. 8. The ratio of the admission periods was noted within 10 days was 45.6%, the median of the admissio was 10.8 days. Brain Neurogic Dis's median was 20.2 days. 9. The therapeutic result was noted the case of improvement was 75.7% in the admission. 10. The ratio of the Out-patients department after discharging was 53.7%, in the case of Brain Neurogic Dis. was 60.7%.

아그로박테리움을 이용한 Actinobacillus pleuropneumoniae ApxIIA (ApxII toxin) 유전자 발현 옥수수 형질전환체 개발

김현아,유한상,양문식,권석윤,김진석,최필선,Kim, Hyun-A,Yoo, Han-Sang,Yang, Moon-Sik,Kwon, Suk-Yoon,Kim, Jin-Seog,Choi, Pil-Son 한국식물생명공학회 2010 식물생명공학회지 Vol.37 No.3

To develop edible vaccines for swine, the embryogenic calli (type II) derived from HiII genotype were inoculated with A. tumefaciens strain C58C1 containing the binary vector pMYV611, 613, 616, and V621, 622 and 623 respectively. Six of those vectors carry nptII gene which confers resistance to paromomycin and apxIIA gene producing ApxII toxin which is generated in various serum types of A. pleuropneumoniae as a target gene. The 4,120 callus clones for pMYV611, 5,959 callus clones for pMYV613, 7,581 callus clones for pMYV616, 52,329 callus clones for V621, 48,948 callus clones for V622, and 56,188 callus clones for V623 were inoculated. The frequency of positive response clone was confirmed into range of 2.3% - 4.4% for each vectors by NPTII ELISA kit assay, and the selected callus clones of them were finally 3 callus clones from pMYV611 (0.07%), 4 callus clones from pMYV613 (0.07%), 2 callus clones from pMYV616 (0.03%), 51 callus clones from V621 (0.1%), 72 callus clones from V622 (0.15%), and 102 callus clones from V623 (0.18%) respectively. From the selected callus clones of each binary vector, the integration of the apxIIA gene into maize genome was detected from 2 plants of pMYV613 and 2 plants of V623 by Southern blot analysis. 돼지 흉막폐렴백신을 개발하기 위해 옥수수 HiII genotype 으로부터 유도한 type II형의 배발생캘러스를 식물발현벡터 pMYV611, pMYV613, pMYV616, V621, V622 및 V623로 형질전환시킨 Agrobacterium (C58C1)과 공동배양 하였다. 이들 식물발현벡터는 paromomycin 항생제 저항 유전자인 NPTII 선발마커와 표적 유전자로서 흉막폐렴균의 여러 가지 혈청을 생산하는 apxIIA유전자로 재조합하여 구축하였다. 식물발현벡터pMYV611, pMYV613, pMYV616, V621, V622 및V623의 경우 각각 4,120개, 5,959개, 7,581개, 52,329개, 48,948개 및 56,188개의 캘러스 클론을 Agrobacterium과 공동한 후 NPTII assay kit에 의해 nptII유전자의 발현빈도를 조사한 결과 각 벡터별로 2.3-4.4%의 캘러스 클론에서 항체결합 양성반응을 보였고, 이들 중 최종적으로 선발된 형질전환 캘러스 클론은 pMYV611에서 3개 (0.07%), pMYV613에서 4개 (0.07%), pMYV616에서 2개 (0.02%), V621에서 51개 (0.1%), V622에서 72개 (0.15%) 및 V623에서 102개 (0.18%)를 각각 얻었다. 형질전환된 캘러스 클론으로부터 재분화된 식물체에서 유전자 도입여부를 Southern 분석으로 통해 확인한 결과 pMYV613에서 2개 식물체 및 V623에서 얻은 2개 식물체에서 각각 확인되었다.

투습도 측정방법에 따른 스포츠웨어용 투습직물의 투습특성

김현아,김승진,Kim, Hyun-Ah,Kim, Seung-Jin 한국의류산업학회 2017 한국의류산업학회지 Vol.19 No.4

This study investigated water vapor permeability of the 73 breathable fabrics for sports-wear according to the materials, finishing methods and fabric structural parameters. The water vapor permeability by KS K 0594 method of PET breathable fabric was superior than that of nylon one, in addition, water vapor permeability of coated or laminated breathable fabrics were higher than those of hot melt or dot laminated fabrics. The water vapor permeability of breathable fabric was dependent on the thickness, weight and density, which was consistent with measuring method. However, water vapor permeability according to materials and finishing method showed different results according to measuring method. The correlation coefficient of WVP of PET breathable fabrics between ISO and KS K measuring methods was -0.83 and the correlation coefficient of WVP of coated breathable fabrics was -0.72 and -0.71 for KS K and ASTM and -0.72 for KS K and ISO in hot melt laminated breathable fabrics. According to regression analysis, WVP of PET breathable fabric by both KSK and ISO measuring methods was highly dependent upon on the density and weight. In addition, WVP of hot melt laminated breathable fabric was highly dependent upon thickness, weight and density. Therefore, relevant measuring method for WVP of breathable fabrics has to be adopted to measure precise breathability.

스포츠 의류용 투습직물의 역학특성과 의류형성성능 특성

김현아,Kim, Hyun Ah 한국의류산업학회 2017 한국의류산업학회지 Vol.19 No.5

This study investigated garment formability of the 73 breathable fabrics for sports-wear garment and their fabric mechanical properties were measured using KES-FB and FAST systems. Predicted garment formability from the mechanical properties measured using KES-FB and FAST systems was compared and discussed with fabric structural parameters. In addition, virtual 3D simulation silhouette by I-designer CAD system wear appearance by simulation using 3D CAD system. And compared with FAST finger chart by mechanical properties of FAST system. The correlation coefficients of extensibility and shear modulus between KES-FB and FAST systems were high, however, bending rigidity and compressibility showed relatively low correlation coefficients. The correlation coefficient of garment formability of breathable fabrics between KES-FB and FAST systems was 0.82. It revealed that garment formability can be predicted from fabric mechanical properties by KES-FB and FAST systems. The garment formability of nylon breathable fabric was higher than that of PET one, and the garment formability of laminated breathable fabric showed the highest value compared to coated, dot and hot melt laminated breathable fabrics. It revealed that garment formability of breathable fabrics for sports-wear can be predicted from fabric mechanical properties and garment formability was dependent on the materials, finishing method and fabric structural parameters.

아메드 방수유출장치 삽입수술과 병합수술의 효과

김현아,박가희,박태관,온영훈,Hyun A Kim,Ka Hee Park,Tae Kwann Park,Young Hoon Ohn 대한안과학회 2014 대한안과학회지 Vol.55 No.4

Purpose: To evaluate surgical results after combined operation associated with Ahmed glaucoma valve (AGV) implantation. Methods: A retrospective review was performed for 71 eyes of 67 patients who underwent combined operation associated with AGV implantation from June 2003 to August 2012. Results: Pars plana vitrectomy or phacoemulsification combined with AGV implantation were performed for 16 eyes and AGV implantation alone was performed in 55 eyes. Mean IOP (mm Hg) and the number of antigluacoma agents for both the combined and single groups showed a statistically significant decrease (combined/single; <em>p</em> = 0.008/0.000, 0.002/ 0.000). Visual acuity (log MAR) was improved, but these differences were not statistically significant (combined/single; <em>p</em> = 0.309/0.052). Conclusions: Combined vitrectomy or phacoemulsification and AGV implantation for intractable glaucoma with vitreoretinal disease or cataract is considered to be the primary procedure because of its equivalent efficacy in lowering IOP, improving visual acuity and decreasing the number of glaucoma agents. J Korean Ophthalmol Soc 2014;55(4):578-584

대단위 도시개발사업 새로운 시장인가, 불가피한 선택인가

김현아,Kim, Hyeon-A 한국주택협회 2007 주택과 사람들 Vol.205 No.-

현대건설의 김포 고천, 삼성물산의 용인 동천 등 대형 건설사들이 대단위 도시개발사업에 뛰어들었다. 미니 신도시급 규모인 도시개발사업에 건설업체의 관심이 높다. 건설업체들이 택지난 해소를 위해 지자체와 협의를 거쳐 대단위 도시개발사업에 적극적으로 나서고 있다.

동복호 (同福湖) 유입하천의 조류증식능에 (藻類增植能) 관한 연구

김현아,이나나,유춘만,위성욱,주현수,이종빈,위인선 ( Hyun Ah Kim,Na Na Lee,Chun Man Yu,Seong Uk Wui,Hyun Soo Joo,Jong Bin Lee,In Sun Wui ) 한국환경생물학회 1995 환경생물 : 환경생물학회지 Vol.13 No.1

On filtered and autoclaved water samples from the upper stream of Lake Tong-Bok, physico-chemical analysis and algal growth potential (AGP) test using Selenastrum capricornutum Printz were performed from October, 1991 to July, 1992 in order to assess fertility potential of the lake and to identify possible limiting nutrients. Water temperature of the lake was fluctuated from 3.8℃ to 30.7℃, the range of pH was 6.0 to 8.0, the level of dissolved oxygen ranged from 5.5㎎/ℓ to 14.4㎎/ℓ, biochemical oxygen demand varied from 0.3㎎/ℓ to 7.6㎎/ℓ, and suspended solides was fluctuated from 0.7 ㎎/ℓ to 24.5㎎/ℓ. Results of nutrient analysis were as followings. The level ammonia was from ND(<0.01㎎/ℓ) to 0.74㎎/ℓ, nitrite and nitrate were ND(<0.01㎎/ℓ) - 0.06 ㎎/ℓ, 0.09㎎/ℓ - 1.33㎎/ℓ respectively. The range of phosphate level varied from ND(<0. 01㎎/ℓ) -0.24㎎/ℓ, and total phosphorus was fluctuated 0.04㎎/ℓ - 0.63㎎/ℓ. Algal growth potentials of the filtered and filtered after autoclaved samples were 0.1 ㎎/ℓ - 21.0㎎/ℓ and 2.9㎎/ℓ - 13.9㎎/ℓ respectively during surveyed period. AGP of the filtered after autoclaved were higer than those of the filtered only except some specific sites. The points of maximum growth were measured after addition of N, P, Fe and EDTA each in comparison with unenriched (control) samples. Phosphate appeared to be the major limiting element in AGP test for a tested organism throuhgout the year, especially during spring and summer. According to trophic level by Sudo(1980), it was estimated that Tong-Bok stream was eutrophic, Nae-Puk stream was oligo-mesotrophic, and all other streams of Lake Tong-Bok were mesotropic.

장기 임대 주택 공급 확대와 주택 시장 안정

김현아,Kim, Hyeon-A 한국주택협회 2007 주택과 사람들 Vol.202 No.-

정부가 지난 1월 31일 부동산 대책을 또 내놨다. 장기 임대 주택을 지속적으로 확대 공급하겠다는 게 골자다. 또한 새롭게 펀드형 임대주택이라는 방식까지 제안하고 있다. 임대 주택의 실효성 여부와 이것이 주택 시장 전반에 미치는 영향에 대해 알아보자.

심폐소생술금지 동의 전·후 말기암환자의 연명치료 변화

김현아,박정윤,Kim, Hyun A,Park, Jeong Yun 한국호스피스완화의료학회 2017 한국호스피스.완화의료학회지 Vol.20 No.2

목적: 본 연구는 심폐소생술금지에 동의한 암환자를 대상으로 연명치료 변화를 확인하기 위해 시도된 후향적 조사연구이다. 방법: 연구대상자는 S시에 소재한 A종합병원에서 2013년 1월 1일부터 12월 31일까지 종양내과 병동에 입원치료하고 사망한 암환자로 심폐소생술금지에 동의한 250명이 선정되었으며, 이중 심폐소생술금지를 입원당일 동의하였거나(N=40) 동의 후 3일 이내 사망한(N=10) 경우는 제외하였다. 대상자의 특성과 연명치료의 변화를 의무기록을 통해 조사하였으며, 심폐소생술금지 지시 동의 전 1일과 심폐소생술금지 지시 동의 후 3일 혹은 사망시점까지 조사하여 유지, 중단, 추가로 연명의료 변화를 판정하였다. 수집된 자료는 SPSS Win 21.0 프로그램을 이용하여 분석하였다. 결과: 연구대상자는 총 200명으로, 50~59세 나이 군이 36.0%로 가장 많이 차지하였고 남자가 62%였다. 재원일은 15일이었고, 입원하여 10일되는 시점에서 심폐소생술금지에 동의하였다. 심폐소생술금지에 동의 후 35.7~100%에서 연명치료가 계속 유지되었다. 인공호흡기 치료는 중단되지 않고 100% 유지되었으며, 수혈(37%), 혈액검사(37.4%), 산소요법(23.5%) 순으로 추가되었다. 중단된 연명치료 중 가장 빈도가 높은 것은 수혈(13.5%)이었고, 다음으로 혈액검사(11.5%), 비경구성 영양제투여(8.5%) 순이었다. 결론: 심폐소생술 지시 동의 후에 대부분 연명치료는 계속되었고 중단되는 경우는 드물었다. 의료진과 가족들 간의 연명치료 범위에 대한 이견을 좁히고, 무의미한 연명치료 중단에 대한 결정을 합의하기 위한 적극적인 논의가 요구된다. Purpose: This study investigated changes in life-sustaining treatments in terminally ill cancer patients after consenting to a do-not-resuscitate (DNR) order. Methods: Electronic medical records were reviewed to select terminally ill cancer patients who were treated at the oncology unit of the Asan Medical Center, a tertiary hospital in South Korea and died between January 1, 2013 and December 31, 2013. Results: The median (range) age of the 200 patients was 59 (22~89) years, and 62% (124 persons) were male. Among all patients, 83.5% were aware of their medical condition, and 47.0% of the patients had their DNR order signed by their spouses. The median of the patients' hospital stay was 15 days, and time from admission to DNR decision was 10 days. After signing a DNR order, 35.7~100% of the life-sustaining treatments that had been provided at the time of the DNR decision making were administered. The most commonly discontinued interventions were transfusion (13.5%), blood test (11.5%) and parenteral nutrition (8.5%). Conclusion: It is necessary to define the scope of life-sustaining treatments for DNR patients. Treatment guidelines should be established as well to secure terminal patients' death with dignity after their consent to a DNR order, thereby avoiding meaningless life-sustaining treatments and allowing administration of active terminal care interventions.