http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
지역사회 성인남성에서의 하부요로증상 및 전립선비대증 의료이용과 사회경제적 요인의 관련성
김한해,공경애,이훈재,윤하나,이보은,문옥륜,박혜숙,Kim, Han-Hae,Kong, Kyoung-Ae,Lee, Hun-Jae,Yoon, Ha-Na,Lee, Bo-Eun,Moon, Ok-Ryun,Park, Hye-Sook 대한예방의학회 2006 예방의학회지 Vol.39 No.2
Objectives : We wanted to evaluate the medical underutilization for benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among Korean elderly men and we wanted to determine their associated factors. Methods : This study was conducted on 239 men with LUTS and 116 men with BPH who were compatible with the diagnostic criteria from a total of 641 participants. These participants were over 50 years old and they were randomly chosen in a community-based study for estimating the prevalence of BPH. Using a self-reported questionnaire, we surveyed the sociodemographics, health status, quality of life, lower urinary tract symptoms, medical utilization and reasons for not seeking treatment. Results : Only 27.6% of the men with LUTS and 31.0% of the men with BPH reported having visited a doctor for urinary symptoms. The reasons for not visiting a doctor were, in order of responses from the group with LUTS: 'considered the symptoms as a part of the normal ageing process', 'not enough time to visit a doctor', 'financial difficulty' and 'the symptoms were not severe or bothersome'. Regarding BPH, the responses were the same as those of the group with LUTS however, 'financial difficulty' placed second. Among the men with experience of visiting a doctor for urinary symptoms, 33.3% of those with LUTS and 28.1% of those with BPH were not treated. The most common reason in both groups was 'the symptoms were not severe to be treated'. On a multiple logistic regression analysis, the larger size household (odds ratio (OR) 3.03, 95% confidence interval (CI)=1.40-6.54) and an unsatisfactory quality of life related with urinary symptoms (OR 2.98, 95% CI=1.23-7.21) were associated with medical utilization in the group of LUTS. For BPH, the current employment status was related with the medical utilization (OR 2.80, 95% CI=1.10-7.11), in addition to the larger size household (OR 3.24, 95% CI=1.14-9.21). Conclusions : Many men with urinary symptoms do not visit a doctor. This medical underutilization for people with LUTS and BPH may be associated with economic status in Korea.
김한해,조안나,이무영,양순모,Xiaozhi Ma,Pamela C. Ronald,이인석 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.2
Bacterial species in the genus Xanthomonas infect virtually all crop plants. Although many genes involved in Xanthomonas virulence have been identified through molecular and cellular studies, the elucidation of virulence-associated regulatory circuits is still far from complete. Functional gene networks have proven useful in generating hypotheses for genetic factors of biological processes in various species. Here, we present a genome-scale co-functional network of Xanthomonas oryze pv. oryzae (Xoo) genes, XooNet (www.inetbio.org/xoonet/), constructed by integrating heterogeneous types of genomics data derived from Xoo and other bacterial species. XooNet contains 106,000 functional links, which cover approximately 83% of the coding genome. XooNet is highly predictive for diverse biological processes in Xoo and can accurately reconstruct cellular pathways regulated by two-component signaling transduction systems (TCS). XooNet will be a useful in silico research platform for genetic dissection of virulence pathways in Xoo.
2’-Fucosyllactose가 마우스 배변 및 장내 미생물에 미치는 영향
김한해,김연지,김광연,신철수,윤종원,전선민,김보미,방정수,김경호 한국식품영양학회 2023 韓國食品營養學會誌 Vol.36 No.3
Prebiotics are known as components of intestinal microbiota that can improve and maintain human health status by stimulating the growth and activity of the intestinal tract as a method of controlling the intestinal environment. In this study, we examined whether 2’-fucosyllactose (FL) could affect intestinal microbial population and bowel activity. Water content and frequency of mouse feces were increased in the 2’-FL treated group at a high concentration (1,000 mg/kg), with brightness of the color enhanced and physical properties diluted. In addition, intestinal microbial analysis showed that harmful bacteria Clostridium and Staphylococcus strains were decreased and beneficial bacteria such as Lactobacillus strains were markedly increased in the group treated with a high concentration of 2’-FL compared to those in the control group. These findings suggest that administration of 2’-FL can maintain healthy bowel activity by reducing harmful bacteria population and improving diluted physical properties.
일본의 차기 국민건강증진계획: 『건강일본 21(제2차)』의 최종 평가 결과 및 『건강일본 21(제3차)』의 주요내용
김한해 한국보건교육건강증진학회 2023 보건교육건강증진학회지 Vol.40 No.5
Objectives: This study analyzed the final evaluation report of the second term of “Health Japan 21” alongside the critical aspects of the third term, “Health Japan 21”, while exploring their potential implications. Results: Since its launch in 2000, “Health Japan 21” has continuously increased healthy life expectancy through achievements in establishing a legal framework for health promotion, implementing diverse health projects, and leveraging the latest technologies. Nevertheless, despite progress, risk factors related to lifestyle diseases are worsening steadily, and health equity indicators are not demonstrating improvement. Based on these achievements and limitations, the third term of “Health Japan 21” will prioritize the vision of “Realization of a sustainable society where all citizens can live healthy and enriched lives.” It will emphasize the principles of inclusion and effective implementation as guiding factors. The improvements in the new plan can be outlined as bolstering health equity, improving the quality of the social environment conducive to health, and strengthening execution through cooperation and leveraging new technology. Conclusion: Korea has already been promoting the 5th National Health Plan (HP2030) by reflecting these changes in the social environment. Nonetheless, there is a need to derive new policy tasks from the perspective of inclusion and implementation in the future.