황련해독탕 추출액의 각막염 원인균에 대한 항균효과

김인수,서진종,김광곤,하동룡,신민구,김의수,전상윤,Kim, In-Soo,Seo, Jin-Jong,Kim, Kwang-Gon,Ha, Dong-Ryong,Shin, Min-Koo,Kim, Eui-Su,Jeon, Sang-Yun 대한한방내과학회 2014 大韓韓方內科學會誌 Vol.35 No.3

Objectives: The goal of this project was to measure the antibacterial effectiveness of Hwangryunhaedok-tang (barberry root decoction for detoxification) and its constituents. All of the active ingredients including the final product were prepared using high-pressure sterilization for use as medicinal eye drops. The varying forms of Hwangryunhaedok-tang (barberry root decoction for detoxification) were used to treat Staphylococcus epidermidis and Enterococcus faecalis which are found in keratitis. Methods: The antibacterial effect was measured by observing the presence or absence of antimicrobial activity when treated with varying concentrations of Hwangryunhaedok-tang extract. The tests were performed using a dosage of $70{\mu}l$ dosages of 100%, 50%, 10% and 1% the extracted solution by the minimum growth inhibitory concentration measurement. Antimicrobial activity was measured by examining the correlation between dosage strength and bacterial activity from $70{\mu}l$ to $10{\mu}l$ at the same concentration. Results: 1. Hwangryunhaedok-tang (barberry root decoction for detoxification), Phellodendri Cortex, and gardenia didn't show any antimicrobial effects against S. aureus, S. epidermidis, or E. faecalis. 2. Barberry root showed antimicrobial effects against S. aureus and S. epidermidis depending on the levels of concentration but didn't show any antimicrobial effects against E. faecalis. 3. Skullcap showed antimicrobial effects against S. aureus and S. epidermidis when a dosage of 100% extract $70{\mu}l$ was used. However, did not show any antimicrobial effects at all against E. faecalis. Conclusions: Hwangryunhaedok-tang (barberry root decoction for detoxification) and its constituents such as barberry root, phellodendri cortex, skullcap, and gardenia, can be used as an alternative to antibiotic medicinal eye drops to treat keratitis. However, further research on effective uses of and efficient extraction methods are needed.

양계 농업인의 작업장 환경 및 개인보호구 착용 실태조사

김인수,김경란,이경숙,채혜선,김성우,Kim, Insoo,Kim, Kyung-Ran,Lee, Kyung-Suk,Chae, Hye-Seon,Kim, Sungwoo 한국환경보건학회 2014 한국환경보건학회지 Vol.40 No.6

Objectives: This study was conducted to investigate the actual condition of the farm work environment and personal protective equipment as part of the effort to improve livestock work for the safety and health of poultry farmers and provide basic data for establishing plans to improve and develop personal protective equipment. Methods: For this purpose, a questionnaire survey on general information about stables, the poultry work environment, accidents, the wearing of work clothes and personal protective equipment, and the level of awareness related to personal protective equipment was conducted among 148 poultry farmers. Results: As a result, it was found that poultry workplace environment was exposed to such risks as fine dusts; organic dusts; poisonous gases; odorous substances; chicken excrement; contact with chickens, bacteria or viruses; and accidents related to machine operation. Thirteen percent of respondents suffered severe respiratory diseases, and the most frequently injured sites due to accidents were the hands (25.7%), knees (23.8%), arms (17.3%), and head (10.9%). The most frequent type of accident was collisions between the body and obstacles or machinery during movement (36.4%), followed by erroneous machine operation such as feeders and electric shocks (8.5%). Regarding the wearing of work clothes and personal protective equipment, 51.7% of the respondents wore worn-out clothing or everyday clothes, whereas only 32.0% wore work clothes. The percentage of farmers who wore proper protective equipment for the work environment during poultry work was 48.4%. The most frequently used type of protective equipment was boots (38.9%), followed by mask (36.7%), gloves (36.3%), appropriate work clothes (22.6%), quarantine clothes (17.6%), helmets (13.4%), and goggles (12.6%). The rate of wearing goggles was low because they were considered inconvenient and lowered work efficiency. Furthermore, they purchased everyday products available on the market for their personal protective equipment which were not appropriate for maintaining safety in an actual harmful environment and its consequent risks. As a result of the survey of the awareness level related to personal protective equipment, their levels of awareness of accidents and attitude proved to be average or higher, but the practice of wearing protective equipment and the level of knowledge and management of personal protective equipment were lower. Conclusion: This survey found that the wearing status of personal protective equipment among poultry farmers was insufficient even though they were exposed to risks. Most respondents were aware of the necessity of wearing personal protective equipment and of the potential for accidents, but they did not wear proper protective equipment. Their wearing rate was low due to a lack of knowledge about protective equipment, as well as the inconvenience of wearing it. Therefore there is a need to improve and develop specialized personal protective equipment for respiration, hands, and eyes, as well as work clothes that can protect farmers from major harmful matter that is generated in the poultry workplace. Based on the results of this investigation, we will conduct further studies on the required performance and design directions of personal protective equipment while collecting more objective data through field-oriented assessments.

Smoothe Handoff 지원을 위한 빠른 인증 알고리즘

김인수,김기천,김현곤,Kim, In-Su,Kim, Gi-Cheon,Kim, Hyeon-Gon 한국정보처리학회 2002 정보처리학회논문지 C : 정보통신,정보보안 Vol.9 No.1

IMT-2000망 핵심기술은 mobile IP를 이용하는 북미의 3G packet data system과 GSM망과 연계를 하는 유럽의 GPRS로 구분할 수 있다. 이러한 IMT-2000망 핵심기술은 글로벌한 로밍을 위해 Mobile IP도입을 추진하고 있다. Mobile IP상에서는 RADIUS나 DIAMETER같은 AAA 서버가 다이얼 업 컴퓨터의 인증, 허가 서비스를 제공하기 위해 사용되고 있는데, 이것은 MN에게 매우 중요하다. Mobile IP는 MN과 HA간에 강력한 인증을 요구하기 때문이다. 본 논문에서는 이러한 IMT-2000 환경에서 고려되고 있는 Smooth Handoff 기법에서 효과적인 AAA프로토콜의 적용에 관하여 논한다. IMT-2000 technologies are divided 3G packet data system that using mobile IP and GPRS that based on the GSM networks. These technologies Push introduce mobile IP to support seamless roaming. In mobile If environments, use AAA server such as RADIUS or DIAMETER to provide authentication service for dial-up computers. This factor is important for mobile nodes. Mobile If require strong authentication between mobile nodes and home agents. We propose application of AAA protocols for smooth handoff mechanism in IMT-2000 environments.

산업기술(産業技術)의 변화형태(變化形態)와 대응책(對應策)

김인수,Kim, In-Su 한국개발연구원 1979 韓國 開發 硏究 Vol.1 No.4

Maillard 반응생성물의 돌연변이원성에 대한 해조 및 야채추출물의 억제효과

김인수,김선봉,박영호,KIM In-Soo,KIM Seon-Bong,PARK Yeung-Ho 한국수산과학회 1994 한국수산과학회지 Vol.27 No.2

The desmutagenic effects of seaweed and vegetable extracts were investigated on the mutagenicity of Maillard reaction products (MRP) obtained from equimolar amounts of glucose and amino acid (arginine and lysine${\cdot}$HCl) for Salmonella typhimurium TA 100 without S9 mix. The mutagenicities were inhibited by water-soluble extracts of seaweeds(laver, sea-straghorn, sea-mustard and tangle) and vegetables(ginger, garlic, onion, chinese-pepper, green-onion and cabbage). Cabbage, chinese-pepper, green-onion and sea-straghorn exhibited especially high desmutagenic effects. The desmutagenicities of these extracts(cabbage, green-onion and sea-straghorn) except for sea-straghorn were decreased by heat treatment at $100^{\circ}C$ for 10 min. It is assumed that the desmutagenic effect of seaweed and vegetable extract is due to the reducing power and action of enzyme such as peroxidase and catalase. 식품의 가공 저장 및 조리 중에 일어나는 식품성분간의 반응 중 대표적인 반응으로 알려져 있는 Maillard 반응생성물의 돌연변이원성에 대한 그 억제 기구를 밝히기 위하여 glucose-arginine계 및 glucose-lysine${\cdot}$HCl계 Maillard 반응 생성물에 일상 생활에서 많이 섭취하고 있는 해조류 및 야채류의 수용성 추출물을 첨가하여 그 억제효과를 조사하였고, 아울러 이들 수용성추출물의 가열($100^{\circ}C$, 10분)에 따른 억제효과의 영향에 대해 조사 검토하였다. 그 결과, 실험에 사용한 해조류 및 야채류 수용성 추출물 전부가 돌연변이원성 억제효과를 나타내었고, 특히 양배추, 파, 산초, 및 청각에 있어서 억제효과가 높게 나타났다. 가열한 경우, 야채류의 돌연변이원성 억제효과는 감소하였으나 해조류는 크게 영향을 받지 않았다. 이 결과로 미루어 보아 당-아미노산계 Maillard 반응생성물의 돌연변이원성 억제에 해조류 및 야채류 추출물에 존재하는 환원성 물질, 고분자 물질 catalase 및 peroxidase와 같은 효소 등이 일조를 하는 것으로 나타났다.

재유화형 분말수지와 고로 슬래그 미분말을 혼입한 폴리머 콘크리트의 압축강도 및 내산성

김인수,성찬용,Kim, In-Su,Sung, Chan-Yong 한국농공학회 2008 한국농공학회논문집 Vol.50 No.5

This study was performed to evaluate the compressive strength and acid-resistant of polymer concrete using redispersible polymer powder(RPP) and blast furnace slag powder(BSP). Material used were ordinary portlant cement, recycled coarse aggregate, natural fine aggregate, redispersible polymer powder and blast furnace slag powder. The main experimental variables were the substitution ratio of redispersible polymer powder and blast furnace slag powder, when the substitution ratios of RPP were 0, 1, 2, 3, 4, 5 and 6%, and those of BSP were 10%. The compressive strength and acid-resistant of polymer concrete using RPP and BSP were compared with those of ordinary concrete(Basis). When the substitution ratio of RPP was 1%, at age of 28 days, the compressive strength were more higher than those of Basis by 24%, and it was decreased with increasing the RPP content, respectively. Also, the water absorption ratio was decreased with increasing the RPP content. But, the acid-resistant was improved with increasing the RPP content.

THE EFFECT OF DIFFERENTIAL MODULATION OF N-METHYL-D-ASPART ATE RECEPTOR ON THE VIABILITY OF PRIMARY CULTURED NORMAL HUMAN ORAL KERATINOCYTES

김인수,이원,김성훈,최봄,Kim, In-Soo,Lee, Won,Kim, Seong-Hun,Choi, Bohm Korean Association of Maxillofacial Plastic and Re 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.4

In the present study, I investigated the effects of N-methyl-D-aspartate (NMDA), arachidonic acid (AA), and Nitric Oxide Synthase Inhibitor (NOS-I), alone or in combination, on the viability of cultured primary normal human oral keratinocytes (NHOK). Specifically, we examined whether AA and NOS-I could protect primary NHOK from glutamate cytotoxicity. The purpose of this study was therefore the preliminary study for the examination of the interaction between these agents and NHOK in order to elucidate the mechanisms by which epithelial growth and regeneration are regulated. NHOK were obtained from gingival tissue of 20 individuals aged 20 to 29, and third passage (P3) cells were used for this study. Cell viability was measured by the MTT assay. NMDA and NNA, a calcium dependent NOS inhibitor, induced an initial increase in cell number, which subsequently decreased by the $7^{th}$ day. Low concentration of AA ($0.5\;{\mu}M$ & $1\;{\mu}M$) induced an increase in cell number while high concentrations of AA ($5\;{\mu}M$ & $10\;{\mu}M$) induced a decrease in cell number. The decrease in cell number induced by NMDA at the $7^{th}$ day was abolished by the addition of low concentrations of AA ($0.5\;{\mu}M$ & $1\;{\mu}M$) or NOS inhibitors. Low concentrations of AA ($0.5\;{\mu}M$ & $1\;{\mu}M$) or NOS inhibitors may protect the NHOK from NMDA induced cytotoxicity. These reactions might be related to the NMDA receptor in the cell and the change of the intracellular calcium ion concentration.

DSM 프로그램별 효과측정 및 평가연구(하)

김인수,문종철,Kim, In-Soo,Moon, Jong-Cheol 한국전기기술인협회 1997 電力技術人 Vol.173 No.1

향후 최대전력 부족예상으로 수요관리 대상기기 확대보급이 불가피할 것으로 예상되므로 주요 대상기기 중심으로 수요관리 프로그램의 본격적인 시행에 앞서 그동안 외국의 자료나 메이커들의 공급사양에만 의존한 채 예측되어 오던 수요관리 효과를 현장실측을 통해 보다 정밀하게 분석한다.

고자기학(古磁氣學)의 방법(方法) (I)

김인수,Kim, In-Soo 대한자원환경지질학회 1984 자원환경지질 Vol.17 No.2

For the discussion of palaeogeomagnetic field direction and the movement and rotation of geotectonic blocks it is prerequisite to eliminate the secondary remanent magnetization component out of the NRM vector of given rock samples. Among various techniques alternating field and thermal demagnetization methods are most easily applicable and most widely used ones. Physical principle underlying these methods is the concept of relaxation time: Either with an action of external magnetic field or with an elevated temperature relaxation time of magnetic minerals can be drastically shortened. It has been furthermore shown experimentally that the secondary remanent magnetization can be more easily demagnetized than the primary remanent magnetization. Through careful stepwise demagnetization it should also be possible to discriminate the kind of various remanent magnetizations. In addition to the introduction to the underlying physical principles and experimental results of the alternating field and thermal demagnetization this paper gives various practical tips in earring out the demagnetization experiments. Each alternating field and thermal demagnetization instrumentation which is easily adaptable to domestic palaeomagnetic laboratories is also introduced. This paper provides a compact and practical introduction to the methods in palaeomagnetism and would be of interest to present workers and to those who want to embark on research in this field.

Cool Asphalt Pavement(열섬완화 아스팔트 포장) 기술

김인수,한의석,이광호,Kim, In-Su,Han, Ui-Seok,Lee, Gwang-Ho 한국도로학회 2008 한국도로학회지 Vol.10 No.1