한국인에서 미세단백뇨의 유병률 및 임상적 특성

김은란 ( Eun Ran Kim ),성기철 ( Ki Chul Sung ),전창욱 ( Chang Uk Chon ),권창희 ( Chang Hee Kwon ),고영율 ( Young Lyul Koh ),이현종 ( Hyun Jong Lee ),박성근 ( Sung Kun Park ),이도영 ( Do Young Lee ),윤지호 ( Ji Ho Yun ),김병진 ( By 대한내과학회 2006 대한내과학회지 Vol.70 No.6

Background: Microalbuminuria (MA) is independent predictor of cardiovascular disease and it cause mortality regardless of the presence of diabetes (DM) and hypertension (HTN). However, few published studies on this topic have been reported in Korea. Therefore, we investigated the MA prevalence and relationship between MA, insulin resistance and cardiovascular risk factor. Methods: A total of 5,915 (3,053 men and 2,852 women) health screen examinees were enrolled in this study. We measured the anthropometric and biochemical parameters of the atherogenic indexes. Results: The MA prevalence was 7.7% in all participants. The prevalence of MA in the men and women was 9.5% and 5.7%, respectively. Elevated levels of serum fasting glucose, serum fasting insulin, HOMA index, total cholesterols, LDL cholesterol, TG, Body Mass Index (BMI) and the systolic and diastolic blood pressure were significantly associated with MA. The results of multiple logistic regression analysis about MA showed that frequent drinking, low BMI, newly diagnosed DM and elevated levels of HOMA index and blood pressure were significantly associated with MA prevalence. Also, excluding newly diagnosed diabetic and hypertensive subjects, the MA prevalence was 5.7% (6.9% in men, 4.7% in women) and in multiple logistic regression analysis, the MA prevalence significantly increased in the individuals with pre-HTN rather than in the normotensives. Conclusions: The MA prevalence was 7.7% in all subjects. Except the newly diagnosed diabetic and hypertensive subjects, it was 5.7%. The MA prevalence was significantly increased in the individuals with pre-HTN rather than in the normotensives and MA was related with insulin resistance.(Korean J Med 70:617-626, 2006)

기획소화기 질환에서의 경장영양공급

김은란 ( Eun Ran Kim ) 대한소화기학회 2015 대한소화기학회지 Vol.65 No.6

Nutritional support is important because malnutrition is a major contributor to increased morbidity and mortality, decreased quality of life, increased length of hospital stay, and higher healthcare costs. Patients with gastrointestinal disease are at an increased risk of nutritional deterioration due to therapeutic dietary restriction, fasting for the diagnostic tests, loss of appetite due to anorexia or altered nutritional requirement caused by the disease itself. Therefore, it is important that gastroenterologists are aware of the nutritional status of patients and plan a treatment strategy considering patient’s nutritional status. Enteral nutrition is preferred to parenteral nutrition as it is more physiologic, has fewer complications, help to prevent mucosal atrophy and maintain gut barrier function, which decrease intestinal bacterial translocation. Hence, enteral nutrition has been considered to be the most effective route for nutritional support. In this article, we will review enteral nutrition (oral nutritional supplements, enteral tube feeding) as a treatment for the patients with gastrointestinal, liver and pancreatic disease at risk of malnutrition. (Korean J Gastroenterol 2015;65:354-360)

매화의 품종과 건조방법에 따른 화학성분 조성

김용두 ( Yong Doo Kim ),정명화 ( Myung Hwa Jeong ),구이란 ( I Ran Koo ),조인경 ( In Kyung Cho ),곽상호 ( Sang Ho Kwak ),김보은 ( Bo Eun Kim ),김기만 ( Ki Man Kim ) 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2006 한국식품저장유통학회지 Vol.13 No.2

고등학교 생물 ‘생명의 연속성’ 단원 분석

김명란(Myoung Ran Kim),김윤희(Yun Hee Kim),조은희(Eun Hee Cho) 조선대학교 교과교육연구소 2000 교과교육연구 Vol.21 No.1

Recent advances in biotechnology has centered around the field of genetics. Although the likely benefits of biotechnology is obvious, it is assuring that the potential risks has to be carefully weighed. It also rasied new social and ethical issues in everyday life experiences. Thus, biology education especially in the units on biotechnology and genetics should emphasize social implications of the technology. In this study, the “Continuity of Life” unit in high school biology Ⅱ curriculum was analyzed in the context of Science, Technology and society(STS). The unit, “Continuity of Life”, describes basic genetic phenomena and evolution of life. five different high school biology Ⅱtextbooks were chosen and inquiry content dimension, and the inquiry process dimension. Analyses of the inquiry content dimension showed that 40.6% of inquiry activities in the unit were devoted to the evolution part and those for cell division, reproduction and development, and Mendelian genetics were at most 8.7%, 13.0%, and 16.0%, respectively. In the inquiry process dimension. ‘interpreting data and formulating generalization’ and ‘observation and measuring’categories consist of 81.1%. The other categories, ‘seeing a problem and seeking ways to solve it’ and ‘building, testing, and revising the theoretical model’ were under represented. In the context dimension, the scientific context consists of 73.0% and the proportion of the other three categories, individual context, the social context, and the technical context was only 26.1% in total. In conclusion, the analysis of inquiry activities on the “Continuity of Life” unit in five textbooks composed based upon the Sixth Curriculum of High School Education failed to show intimate relationship between science and society and simply concentrated on description and explanation of scientific facts. Provided the fact that the BiologyⅡ is used in the highschool class for students who want to be future natural science majors of who show special interests in natural science, it is important for students to understand the ethical and social issues that recent biotechnology raised and to become scientifically literate and responsible persons.

종설(綜說) : 불면증에 대한 신침요법의 임상시험 최신 동향 -피내침, 이침, 약침, 수지첨 중심으로-

김세란 ( Se Ran Kim ),김은주 ( Eun Joo Kim ),박미연 ( Mee Yeon Park ),최해윤 ( Hae Yun Choi ),김종대 ( Jong Dae Kim ) 대구한의대학교 제한동의학술원 2010 東西醫學 Vol.35 No.3

초기 치매 노인의 일상생활 참여 촉진을 위한 보호자 지침의 개발: 델파이 조사를 중심으로

김서은(Kim, Seo-Eun),구슬기(Koo, Seul-Gi),박상미(Park, Sang-Mi),김정란(Kim, Jung-Ran) 한국노년학회 2017 한국노년학 Vol.37 No.2

본 연구는 치매를 조기에 관리하기 위한 중재 방법의 일환으로, 초기 치매 노인을 위해 보호자가 일상생활에서 쉽게 적용할 수 있는 전문적 중재 내용을 포함한 초기 치매 노인의 일상생활 참여를 촉진할 수 있는 보호자 지침을 개발하는데 목적이 있다. 델파이 기법을 활용한 연구의 절차는 총 3단계로 진행하였다. 첫 단계는 1차 조사로, 외국의 치매 관련 협회나 정부부처에서 발행한 초기 치매노인의 일상생활 참여 촉진 가이드 전략과 관련된 보고서 자료를 수집하여 지침 항목을 추출하여 번안 및 재구조화 한 후 3개 영역, 128개 항목의 초안을 마련하였다. 두 번째 단계는 2차 조사로, 전문가 16인의 내용타당도 검증 및 항목 삭제, 영역 재분류, 내용 통합, 번역체 수정 등의 작업을 거쳤다. 세 번째 단계는 지침의 완성 단계로, 완성된 지침은 8개 영역, 68개 항목 으로 구성되었다: 환경수정 및 보조도구, 일상생활, 건강관리, 의사소통, 심리·정서적지지, 여가활동, 사회참여, 일반적 지침. 또한, 모든 항목은 각 영역 내에서 중요도 값이 높은 순서로 항목을 배치하였다. CVR 평균값은 0.81, 안정도 평균값은 0.15, 합의도 평균값은 0.79이다. 즉, 최종 지침 항목에 대한 델파이 의견이 안정되고, 합의되는 경향의 값을 보였다. 그리고 15명의 델파이 조사에서 CVR은 0.49이상, 안정도는 0.5미만인 경우 더 이상의 델파이 조사를 하지 않아도 되기 때문에 추가적인 조사를 실시하지 않았다. 본 연구에서 개발된 초기 치매 노인의 일상생활 참여 촉진을 위한 보호자 지침은 지역사회에서 거주하는 초기 치매 노인의 독립성을 돕기 위해 보호자 교육용으로 안내하기에 실제적이고, 구체적인 내용을 담은 기초자료로 활용될 것이고, 보호자의 부담을 줄일 것으로 기대한다. 마지막으로, 제한점과 후속연구를 위한 제안점을 논의하였다. The purpose of this study was to develop the caregiver guideline for participation in activities daily living for the elderly with early dementia in home including easily adaptable and professional strategies as early intervetion. The process of this study was 3 stage. First stage, the development of preliminary caregiver guideline as the first stage of this study was to translate to Korean and reclassify the items about caregiver guideline for participation from reports of foreign association or government related dementia, and it consisted of 3 areas, 128 statements for questionnaire for Delphi investigation. Second stage, the guideline was to conduct the content validity, and delete, reclassify, integrate, revise inappropriate items through 2 rounds and 16 Delphi panels. Third stage, the establishment of the final version of caregiver guideline. It consisted of 8 areas: home modification and assistive device, home activities of daily living, health management, communication, psycho-emotional support, leisure activities, social participation, general strategies. All 68 items was arranged in important order. The content validity, stability, agreement index in this study were 0.81, 0.15, 0.79 respectively. When content validity, stability was above 0.49, below 0.5 in Delphi survey with 15 panels, it was not required additional survey. The result of this study meaned that it was not required to additional Delphi survey, and the result was stable and agreeable. This developed guideline was useful and practical to maintain the elderly s with dementia independent and healthy life as education materials for their caregivers, so it will expect to decrease caregiver s burden. Lastly, it stated limitation and suggestion for further study.

이달의 영상 : 간이식 후 위장관 병변으로 발현된 혈전성 미세혈관병증

김은란 ( Eun Ran Kim ),김경미 ( Kyoung Mee Kim ) 대한소화기학회 2011 대한소화기학회지 Vol.57 No.3

박사학위논문에 나타난 간호학 탐구경향

김의숙(Kim, Eui-Sook),김광숙(Kim, Gwang-Suk),김대란(Kim, Dae-Ran),김은정(Kim, Eun-Jeong),성경미(Sung, Kyung-Mi),신현숙(Shin, Hyun-Sook),신혜경(Shin, Hae-Kung),이영자(Lee, Young-Ja),정석희(Jeong, Seok-Hee) 한국간호과학회 2004 Journal of Korean Academy of Nursing Vol.34 No.2

요통환자의 통증행위에 대한 조사연구

이은옥(Lee, Eun Ok),임난영(Lim, Ran Young),김달숙(Kim, Dal Sook),김순자(Kim, Soon Ja),한윤복(Hahn, Yoon Bok),김주희(Kim, Joo Hee),김광주(Kim, Kwang Joo),박점희(Park, Jum Hee),이선옥(Lee, Sun Ok),최순희(Choi, Soon Hee) 한국간호과학회 1987 Journal of Korean Academy of Nursing Vol.17 No.3

백양사 사찰림 비자나무 임분의 테르펜류 잔존량과 성분특성

김애란 ( Ae-ran Kim ),양천은 ( Cheon-eun Yang ),허예나 ( Ye-na Heo ),김강산 ( Kang-san Kim ),박종석 ( Jong-suk Park ),김은일 ( Eun-il Km ),안기완 ( Ki-wan An ),김민희 ( Min-hee Kim ) 한국산림경제학회 2018 산림경제연구 Vol.25 No.1

본 연구는 비자나무 임분내의 NVOCs 잔존량을 규명하고 비자나무에서 방출되는 NVOCs의 성분을 규명하고자 수행하였다. 실험은 2017년 4월부터 10월까지, 총 7회에 걸쳐 장성군에 위치한 내장산국립공원 백양지구 내 비자나무 임분에서 이루어졌다. NVOCs의 포집은 가지에 테틀러백을 씌우고 순수공기를 주입시켜 11시부터 12시까지 포집하는 테틀러백 법과 임분 내에서 직접 포집하는 미니펌프법으로 실시하였다. 테틀러백을 이용한 비자나무의 월별 NVOCs 잔존량은 각각 146,156 pptv/4월, 176,786 pptv/5월, 132,466 pptv/6월, 22,908pptv/7월, 73,782pptv/8월, 38,736pptv/9월, 41,233pptv/10월로 측정되었으며, 비자나무 임분 내에서 측정한 월별 NVOCs는 5,169 pptv/4월, 11,940 pptv/5월, 7,657 pptv/6월, 6,864pptv/7월, 13,912pptv/8월, 2,640pptv/9월, 1,828pptv/10월로 나타났다. NVOCs의 15종에 대한 성분을 7회 평균값을 산출한 결과, limonene이 약 43∼52%로 가장 많은 함량을 차지하고 있었으며 α-pinene 은 약 35∼39%의 비율인 것으로 분석되었다. 비자나무를 대상으로 포집방법의 차이에 따른 NVOCs 잔존량은 최소 15배에서 28배까지 차이를 보였으며, NVOCs 성분의 대부분이 limonene과 α-pinene으로 나타났다. 임분내 NVOCs에 대한 기초자료로서 활용될 수 있을 것으로 사료된다. This study aims to identify the NVOCs(Natural Volatile Organic Compound) retention volume of Torreya nucifera stand and the characteristic of chemical compositions of the NVOCs emitted from it. This experiment was performed seven times in total from April to October, 2017 at Torreya nucifera temple forest of Naejangsan National Park Baekyangsa in Jangseong-gun. Two methods were used as the sampling methods of NVOCs. The first one was to use tedlar bags. After placing a tedlarbag over a branch and leafs, we injected pure air into it and captured NVOCs for 2 hours from 11 a.m. to 12 p.m. The second one was to capture NVOCs directly in a stand of Torreya nucifera used mini pump. When tedlarbags were used, the monthly NVOCs retention volumes of Torreya nucifera were 146,156pptv/April, 176,786pptv/May and 132,466pptv/June, 22,908pptv/July, 73,782pptv /August, 38,736pptv/September, 41,233pptv/October respectively. In addition, when measured using minipump in the stand, the monthly NVOCs retention volumes were 5,169 pptv/April, 11,940pptv /May, and 7,657pptv/June, 6,864pptv/July, 13,912pptv/August, 2,640pptv/September, 1,828pptv/October respectively. In order to identify the characteristic of compositions, 15 kinds of terpenes were analyzed, and their average was calculated seven times. As a result, limonene had the highest percentage of 43 to 52%, and α-pinene accounted for 35 to 39%. The NVOCs retention volume depended on the sampling method from Torreya nucifera stand. The highest NVOCs retention volume was at least 15 to 28 times higher, and most components of NVOCs were limonene and α-pinene. It is believed that NVOCs within the domain can be utilized as a baseline.