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원자력 압력용기용강 SA508Gr. 3의 기계적 특성과 템퍼 파라메타에 관한 연구
김병옥 ( Byoung Ok Kim ),이오연 ( Oh Yeon Lee ) 한국열처리공학회 2012 熱處理工學會誌 Vol.25 No.3
The large forgings used in chemical plants or nuclear power plants are produced by complex heat treatment. because of thickness up to 200 ~300mm and weight up to 200~300ton, setting proper heat treatment cycle is so difficult. In addition, defects of products make companies wasting large money and valuable time. In this study, to reduce try & err, when setting heat treatment of reactor pressure vessel steel SA508Gr.3, carrying out the basic mechanical property test of SA508 Gr.3 and testing hardness of SA508Gr.3 in various tempering temperature. and calculating temper curve with Hollomon-Jaffe.
Cr-Mo계 금형강의 기계적 성질에 미치는 합금원소 및 템퍼링의 영향
김남규 ( Nam Kyu Kim ),김병옥 ( Byoung Ok Kim ),이오연 ( Oh Yeon Lee ) 한국열처리공학회 2012 熱處理工學會誌 Vol.25 No.4
The purpose of this study is to enhance the hardenability and the mechanical properties by the addition of alloying elements such as Ni, Cr, Mo and B for the development of Cr-Mo plastic mold steel with uniform hardness and microstructure. The ingots were prepared by vacuum induction melting and forged to Φ35mm round bar. Forged bars were quenched and tempered at 200~600℃ for 1.5 hour. Jominy test, boron distribution observation, microstructual observation, tensile test and charpy impact test were conducted. It was confirmed that the hardenablity of these steels was improved by increasing of alloying elements and further promoted by the addition of boron. The critical rate of cooling required to obtain the bainitic structure for 0.27C-1.23Cr-0.28Mo-B steel was 0.5℃/sec. Hardness and strength of Cr-Mo steels decreased with increasing tempering temperature, but elongation and reduction of area increased with increasing tempering temperature. However, impact energy tempered at 400℃ showed the lowest value in the range 200∼600℃ due to the temper embrittlement.
급성관상동맥증후군(ACS) 환자에서 유산소운동과 스타틴 약물이 혈중지질과 hsCRP에 미치는 영향
김영주 ( Young Joo Kim ),김철 ( Chul Kim ),안재기 ( Jae Ki Ahn ),방인걸 ( In Keol Bang ),이건주 ( Kun Joo Rhee ),김병옥 ( Byung Ok Kim ),이병권 ( Byoung Kwon Lee ),고충원 ( Choong Won Goh ),변영섭 ( Young Sup Byun ),신영오 ( Youn 한국스포츠정책과학원(구 한국스포츠개발원) 2005 체육과학연구 Vol.16 No.4
본 연구는 급성관상동맥증후군(Acute coronary syndrome; ACS) 환자에 대한 유산소운동과 스타틴약물 요법이 혈중지질과 hsCRP에 미치는 영향을 알아보고자 시행되었다. 연구대상자는 관상동맥증후군으로 입원하여 약물처방 및 경피적 관상동맥 중재술(Percutaneous coronary intervention; PCI)을 받고 운동 프로그램에 의뢰된 환자들로서, 실험군은 스타틴요법과 운동요법을 병행한 병행요법군(n=15)과 운동요법만 시행한 운동요법군(n=14) 그리고 스타틴요법만 시행한 약물요법군(n=8)으로 구성되었다. 실험기간은 병원 내에서 감독 하에 실시한 유산소운동 기간 6주와 자가운동 기간 8주의 총 14주 이었으며 실험기간 동안 지속적인 위험인자 관리 및 운동에 대한 상담을 실시하였다. 실험 전후에 혈중지질(TC, TG, LDL-C, HDL-C) 및 high-sensitivity C-reactive protein(CRP)과 그 밖에 체질량지수(body mass index, BMI), 최대산소섭취량(VO2max) 변화를 확인하기 위하여 연구대상자들에게 실험기간 전후에 각각 채혈, 인체계측, 운동부하검사를 실시하였다. 연구결과 얻어진 자료는 윈도우용 SPSS/PC+version 11.0 통계패키지를 이용하여 처리하였다. 염증반응 지표인 hsCRP를 포함한 혈중지질, BMI, VO2max 변인들의 기간별 집단별 차이를 알아보고자 반복측정에 의한 이원배치 분산분석을 실시하였고, 사후검증으로 t-test와 Bonferroni`s 검정을 적용하였다. 연구 결과는 다음과 같다. 실험 전후에 있어서, 병행요법군에서 HDL-C, hsCRP 수치가 유의하게 증가(p<.05), 감소(p<.01)되었고, VO2max 또한 유의하게 향상되었다(p<.01). 운동요법군에서도 HDL-C 수치가 유의하게 증가되었으며(p<.05), VO2max가 유의하게 향상되었으나(p<.05), 약물요법군에서는 혈중지질을 비롯해 hsCRP, BMI, VO2max 모두에서 의미 있는 차이가 나타나지 않았다. 이상의 결과로 보아, 운동요법과 스타틴요법의 병행요법이 향후 심혈관 질환자의 재발 방지에 긍정적인 효과가 있을 것으로 사료된다. This study was designed to evaluate the effect of aerobic exercise and statin therapy on blood lipids and high-sensitivity C-reactive protein (hsCRP) in patients who had undergone successful percutaneous coronary intervention (PCI). Thirty seven male and female patients were studied. All subjects consist of three groups; 1) treated with statin and exercise (SE, n=15), 2) treated only with exercise (EO, n=14), 3) treated only with statin (SO, n=8). All patients were received medication once daily (aspirin and clopidogrel with or without statin) and completely performed supervised aerobic exercise for 6 weeks and home exercise program for 8 weeks. Instruction for diet and exercise was given continuously during experiment. Laboratory measurement includes serum lipids (TC, TG, HDL-C, LDL-C), hsCRP and body mass index (BMI). Cardiopulmonary capacity (VO2max) was assessed by symptom-limited exercise test. All measurements were performed at baseline and after 14 weeks. The results were as follows. In SE, HDL-C (p<.05) and VO2max (p<.01) were significantly improved, and hsCRP (p<.01) was significantly deceased after therapy. And also, HDL-C (p<.05) and VO2max (p<.05) in EO were significantly improved. But there was no alteration of blood lipids, hsCRP, BMI and VO2max in SO. These findings suggested that combination of exercise and statin therapy was the best rehabilitation in patients treated PCI.
김민근,주혜원,강경필,최병돈,박민석,변영섭,고충원,이건주,김병옥 인제대학교 2006 仁濟醫學 Vol.27 No.-
Acute myocardial infarction(AMI) due to coronary embolism can occur in patients with normal coronary artery. Coronary embolism is believed to be a cause of acute myocardial infarction when emergent coronary angiography shows perfectly normal coronary trees, except for the finding of coronary artery occlusion. In this report, we describe four patients with AMI due to coronary embolism who were successfully treated using a thrombus aspiration device and anticoagulation, and those patients had intracardial thrombus arising from the left atrium due to chronic atrial fibrillation and valvular heart disease. Patients with chronic or paroxysmal atrial fibrillation can present with AMI due to coronary embolism, and thrombus aspiration with percutaneous aspiration device is a feasible treatment option for these patients along with anticoagulation the rapy.
쌀보리로부터 Saccharomyces uvarum을 이용한 알콜 생산
손인호,김병옥,임동준 嶺南大學校 環境問題硏究所 1997 環境硏究 Vol.16 No.2
요약문쌀보리로부터 연료용 에탄올을 생산하기 위해서 Saccharomyces uvarum ATCC 26602를 이용하여 연구하였다. 쌀보리는 상업적 효소를 이용하여 액·당화에 의해 환원당으로 전환되어졌으며 효소의 최적 투여량은 쌀보리 100g당 40㎕ Termamyl 240 L, 200㎕ AMG 200 L, 150㎕ Celluclast 1.5L 그리고 30㎕ Novozyme 188 였다. 고형입자에 의해 발생되는 문제점들을 해결하기 위해 필터반응기에 세포를 재순환시키는 연속에탄올 발효공정을 사용하였다. AbstractThe production of fuel ethanol from the naked barley using Saccharomyces uuarum ATCC 26602 has been studied. Naked barley was converted into reducing sugar by liquefaction and saccharification with commercial enzymes. The opitimal dosages of enzymes were found to be 40/^ Termarnyl 240 L, 200 pS, AMG 200L, 150/rf Celluclast 1.5 L and 30 nH Novozyme 188 per 100 g naked barley. The continuous ethanol fermentation process using a filter reactor with cell recycle was employed to solve many problems caused by solid particles.
발작성 고혈압을 주소로 한 급성 간헐성 포르피리아 1예
신정아,이지선,변영섭,고충원,이병권,김병옥,이건주 白中央醫療院 2004 仁濟醫學 Vol.25 No.1
Acute intermittent porphyria is a disorder that results from partial porphobilinogen deaminase deficiency and accumulation of overproducted porphyrin and its precusors. This makes variable manifestations such as abdominal pain, nausea, vomiting, contipation, peripheral neuropathy, seizure, psychotic symtoms, respiratory failure, tachycardia, and hypertension. When acute paroxysmal hypertension presents, it is difficult to differentiate from pheochromocytoma. We experienced a case of young female with acute intermittent porphyria presenting paroxysmal recurrent headache, palpitation, chest discomfort and paroxysmal hypertension. Initially blood pressure was 160/100 mmHg and checked high paroxysmally on follow up. Rhythm was sinus tachycardia. She did not complain any other specific symptoms. Although her clinical manifestations were suspicious for pheochromocytoma, laboratory findings were not compatible to it. In searching other causes of secondary hypertension mimickng ph대chromocytoma, elevated urine porphobilinogen level was detected and we could make diagnosis of acute intermittent porphyria. If AIP was not beared in mind as a cause of secondary hypertension, diagnosis would be delayed more.