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      • KCI등재후보

        Short-Long R-R Sequence Induced Implantable Cardioverter Defibrillator Shock by Dislodged Lead Even Having Normal Interrogation Parameter

        김기훈,Sang-Hoon Seol,Seung Hwan Kim,Dong-Kie Kim,Doo-IL Kim 대한부정맥학회 2018 International Journal of Arrhythmia Vol.19 No.1

        Inappropriate shocks from an implantable cardioverter defibrillator (ICD) can cause potentially dangerous ventricular arrhythmias and impaired quality of life. We describe a case in which a dislodged lead caused inappropriate ICD shocks through simultaneous sensing of atrial and ventricular signals. Interestingly, repeated short-long R-R sequences were recorded, but ICD interrogation parameters were usually unchanged.

      • KCI등재

        와송 다당체 및 올리고당류의 생리 활성

        김기훈,김은영,김예운,백금옥,김한복,이동석,Kim Ki Hoon,Kim Eun Young,Kim Yea Oon,Baek Geum Ok,Kim Han Bok,Lee Dong Seok 한국미생물학회 2004 미생물학회지 Vol.40 No.4

        와송으로부터 고온 고압의 열수 추출로 다당체 조추출물(OJP1)을 얻어 디스크 확산법, fluorescein diacetate(PDA)법 및 액체 배지 희석법을 통하여 세균과 진균에 대한 항균 활성을 조사하였다. 또한 Sephadex G-50을 통하여 다당체(FI)와 올리고당류(FII)를 분리하고, 이들의 항암 활성을 조사하였다. FI과 FII의 분자량은 각각 30$\~$50 kDa과 1$\~$3 kDa으로 추정되었다. OJP1의 항균 효과는 디스크 확산법에서 Candida albicans가 $20\pm4.9\;mm$의 억제대로 가장 높았으며, Salmonella typhimurium과 Staphylococcus aureus도 각각 $18\pm2.0\;mm$ 와 $17\pm1.0\;mm$의 억제대로 비교적 높게 나타났다. 또한 Escherichia coli와 Pseudomonas aeruginosa에 대해서도 양성 대조군인 프로폴리스보다 높게 나타났으며, FDA법, 액체배지 희석법에서도 비슷한 양상을 나타냈다. OJP1과 Fl, FII의 인체 암세포주와 Sarcoma 180 세포주에 대한 항암 활성을 측정해 본 결과, 이들은 모두 MTT assay와 형태 변화 관찰에서 강력한 암세포주 증식 억제 효과를 나타내었는데, 특히 폐암 세포주인 A549 세포와 자궁 경부암 세포주인 HeLa 세포, 위암 세포주인 AGS에서 현저한 효과를 보였다. 더 나아가 DNA 분절화를 통해 apoptosis 유발 여부를 확인해 본 결과, 대조군에 비해서 이들 물질을 처리한 실험군에서 apoptosis발생을 뜻하는 DNA 분절화 현상이 뚜fut하게 나타났다. 요컨대, OJP1과 Fl, FII는 광범위한 병원성 균주에 대하여 효과적인 항균 활성을 보였으며, 각종 암세포주에 대하여 현저한 항암 활성을 나타내는 것으로 확인되었다. Polysaccharides were prepared from Orostachys japonicus by extration with hot steam water (OJPl). The OIPl fraction was further purified by Sephadex G-50 gel filtration chromatography to produce FI (polysaccharides) and FII (oligosaccharides) fraction. The average molecular masses o fFI and FII fraction were determined to be 3050 kDa and 13 kDa, respectively. The antimicrobial activity of OIPl was tested against 8 strains of bacteria and one strain of yeast by the disc diffusion method, fluorescein diacetate (FDA) method and broth dilution method. The OIPl exhibited a very strong growth inhibition to Candida albicans. The OIPl remarkably sup­pressed the growth of Salmonella typhimurium and Staphylococcus aureus. The OIPl showed higher growth inhibition to Escherichia coli and Pseudomonas aeruginosa than propolis, positive control. When the anticancer activity of the OIPl, FI or FII was examined against human cancer cell lines and the Sarcoma 180 cells, these widely suppressed the proliferation of cell lines in the MTT assay and morphology study. Especially, they remarkably inhibited the growth of A549, HeLa and AGS cells. Also treatment of cancer cells with OJPl, FI or FII induced apoptotic cell death characterized by DNA fragmentation. The OJPl, FI or FII exhibiting various biological activities such as antimicrobial activity and anticancer activity is expected to be developed as new biohealth products.

      • 제대군인 취업에 관한 연구 - 민간기업 취업을 중심으로 -

        김기훈,Kim, Ki-Hoon 대전대학교 군사연구원 2011 군사학연구 Vol.9 No.-

        The Republic of Korea, ranked as the 5th military power according to the size of its ground troops, discharges more than 200,000 manpower to the society annually; more than 13,000 of them are officers. The re-employment rate of discharged military personnels, who experience early retirement of 5 to 15 years compared to general public officers, is very low, only amounting to 53.2%. On the other hand, major developed countries exhibit great national scale of effort to take responsibility in helping the settlement of the soldiers who have dedicated their career for their countries. The re-employment rate amounts to 94%. Fully acknowledging such disparity, this paper examines various policies on discharged members support of developed countries, and aims to suggest developmental model on employment support designed for discharged members in the Republic of Korea.

      • KCI등재

        스마트 폰을 이용한 다기능 용접기 원격 제어 시스템에 관한 연구

        김기훈,정양권,최재호,Kim, Gi-Hoon,Jeong, Yang-Kwon,Choi, Jae-Ho 한국전자통신학회 2014 한국전자통신학회 논문지 Vol.9 No.3

        본 연구에서는 크레이터의 전류, 전압, 가스 제어, 와이어 피더 구동, 정전압 출력 제어, 고주파 제어, 정전류 제어, 및 아크 용접 제어 등을 스마트 폰을 이용하여 다기능 용접기를 쉽게 제어할 수 있는 시스템을 제안하였다. 제안 시스템을 사용하는 경우 90% 정도가 다기능 용접기를 이용하는데 용이하다는 결과를 얻었다. 10%는 있으면 좋겠지만 필요 없다는 대답과 "용이하다"라고 응답한 대상자 90%중 30% 정도는 용접기를 사용하면서 사용 연령층에 따라서 스마트 폰 활용이 "매우 어렵다"라고 응답한 경우도 조사되었다. 그러나 스마튼 폰 이용은 점진적으로 사용자의 연령층이 낮아질수록 효과적임을 알 수 있다. In this study, we are a proposed system that could control a multi-functional welder of the current, voltage of the crater, gas control, the wire feeder's driven, the constant voltage output control, high frequency control, rated current control and the ARC welding control etc., using the mobile-based smart phone. Approximately 90% of user of proposed system are very useful in multi-function welder in their task responded and rest of 10% of the answers don't need it. 30% answered in 90% of the multi-function welding machine according to age group using a smart phone utilizing this "very difficult" at investigated. However, the use of smart phones is gradually lower the user's age group can be seen that effective.

      • KCI등재

        바이러스성 뇌수막염(Viral Encephalitis) 후유기(後遺期) 환아(患兒) 1례(例)에 대한 증례(症例)

        김기훈,신동길,김덕곤,Kim, Ki-Hoon,Shin, Dong-Gil,Kim, Deog-Kon 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.1

        Viral Encephalitis are a serious meningeal infection occurred by various chemical substance. Chief symptoms are headache. hyperesthesia in child and fretting. irritation in infant. Adolescence complain of a retrobulbar pain, fever, vomiturition, photophobia. Fever can cause choreic movement, mental disorder and seizure. Most of patients have complete recovery, but if there are brain lesions, it is bad prognosis. Occasionally patients complain of continuous headache, mental disorder, ataxia and marasmus. We report on a 4-year-old male patient with viral encephalitis. It has been 40 days since disease. He had disorientation mentality, dysphagia and fever.

      • KCI등재

        특발성 진성 성조숙증으로 진단된 소아의 원인 및 임상적 분석

        김기훈,신동길,김대현,Kim, Ki-Hoon,Shin, Dong-Gil,Kim, Dae-Hyun 대한한방소아과학회 2011 대한한방소아과학회지 Vol.25 No.2

        Objectives: The purpose of this study is to estimate genetic and environmental factors, which can affect Idiopathic true Precocious puberty, and to evaluate the clinical and endocrinologic characteristics. Methods: Retrospective and Comparative analysis of 76 children (72 girls and 4 boys) has been diagnosed with idiopathic true precocious puberty, and treated with GnRHa from December 2008 to July 2011. Results: 1. The Average chronological age (CA. yr) of children diagnosed with idiopathic true precocious puberty was $8.40{\pm}0.81$ (girls), $9.93{\pm}0.12$ (boys). 2. The Average height & weight percentile (%ile) of the girls diagnosed with idiopathic true precocious puberty was $67.38{\pm}22.04$, $67.69{\pm}23.20$. 3. The girls' mothers have diagnosed with idiopathic true precocious puberty, and they were shorter than the average. This shows that mother's small height and idiopathic true precocious puberty are closely related to each other. 4. BMI percentile (%ile) of girls diagnosed with idiopathic true precocious puberty was $63.26{\pm}24.86$. 23.6% of children were diagnosed with overweight or obesity. This result shows that obesity and idiopathic true precocious puberty are proportionally related. 5. Birth weights (kg) of the children diagnosed with idiopathic true precocious puberty were $3.16{\pm}0.43$ (girls), $3.15{\pm}0.38$ (boys). 8.3% of children were diagnosed with Intrauterine growth retardation. 6. The Average bone ages (BA. yr) of the children diagnosed with idiopathic true precocious puberty were $10.51{\pm}0.99$ (girls), $12.10{\pm}0.97$ (boys). The Average BA-CA was $2.11{\pm}0.81$ (girls), $2.00{\pm}0.87$ (boys). 7. The Average predicted adults' height (PAH. cm) of the children diagnosed with idiopathic true precocious puberty was $151.61{\pm}4.00$ (girls), $163.50{\pm}2.15$ (boys). The Average MPH-PAH was $6.84{\pm}4.91$ (girls), $6.00{\pm}5.35$ (boys). 8. 23.6% of the children treated with GnRHa were co-treated with Growth Hormone. Conclusions: Estimated factors which cause Idiopathic true precocious puberty are mother's small height, obesity, and Intrauterine growth retardation. However, the studies of Oriental Medicine for Idiopathic true precocious puberty were lacking. Further clinical and experimental researches are needed.

      • KCI등재

        통규탕가미방(通竅湯加味方)의 비질환(鼻疾患) 치료에 대한 임상고찰

        김기훈,조형준,이진용,조백건,Kim, Ki-Hoon,Cho, Hyung-Jun,Lee, Jin-Yong,Cho, Baek-Gun 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.1

        Objective: For last 20 years our living environment has been changed rapidly. Accordingly. there have been many changes in prevalence of diseases; In nasal disease of the pediatrics, the number of children suffering from chronic rhinorrhea and nasal obstruction has been increased. And respiratory symptoms suggesting rhinitis and sinusitis also were increased. Allergic disease is considered as an important cause of this phenomenon while importance of infection as pathogen is fading today. The aim of this study is to investigate the effect of TonggyutangGarnibang on the nasal disease of children. Methods: Children with nasal disease answer the questionnaires on their chief complaints and medical past history on their first visit to our clinic. They were treated 'With TonggyutangGarnibang for 4weeks. After treatment they answered the questionnaire on improvement of their symptoms. Results: Among treated patients, 70 were male(69%) and 32 were female(31%); sex ratio was 2.2.3:l(male:female). And children from 3-8 years old took majority of patients(64%). Major symptoms of children with nasal disease were as follows; nasal obstruction 9lchildren(62%), rhinorrhea 86children(84%), sneezing 63children(62%), cough 63children(62%), snoring 48children (47%), poor appetite 44children(43%), itching 39children(38%), headache 32children(31%), stomache 25children(25%), epistaxis 23children(23%), constipation 17children(17%), diarrhea 12children(12%). Past history and impression of the disease of the patients were as follows; allergic rhinitis(66%), atopic dermatitis(42%), sinusitis(40%), asthma(25%), urticaria(12%). Severity of symptom improved after TonggyutangGamibang treatment, it showed high treatment efficacy as follows; sneezing 70%, cough 70%, rhinorrhea 63%, nasal obstruction 59% Conclusion: This study shows TonggyutangGamibang has distinctive treatment effect on children with nasal disease.

      • KCI등재

        도로 조명용 프로그램과 노면특성 장치의 개발

        김기훈,심상만,김훈,Kim, Gi-Hoon,Sim, Sang-Man,Kim, Hoon 한국조명전기설비학회 1999 조명·전기설비학회논문지 Vol.13 No.2

        평균조도 및 휘도의 계산은 어느 정도 그래픽(graphical)적인 방법 등에 의해서 이루어질 수 있으나, 매우 광범위한 장소에 대한 계산에는 적절한 소프트웨어가 필요하다. 이러한 소프트웨어는 해외에서 이미 개발되어 있으나, 국내에서 설계하기에 적합한 다기능의 프로그램은 없었다. 이에 따라 한글 윈도우에서 실행될 수 있는 형태가 되도록 하는 것을 목표로 하여 프로그램을 개발하였으며, 도로면의 휘도 및 조도 분포뿐만 아니라. ?균 휘도, 평균 조도, 전반 균제도와 차선축 균제도, 임계 휘도 증분, 광막 휘도, 눈부심 등의 계산을 수행하는 프로그램(Lighting Analysis program for Poad, LAPRoad)을 개발하였다. 또한 휘도 계산에 잇어서 노면의 반사 특성은 매우 중요하기 때문에 그 특성을 측정할 수 있는 기구를 개발하고, 콘크리트 도로 반사 특성을 측정하였다. Average illuminaoce and luminance can be calculated by grarhical rrethods to a certain extent, but to calculate for a wide place, a suitable software is needed. Softwares suitable for this purpose have been already developed in foreign nations, but the appropiate softwares for domestic use have not been developed 1berefore a program is develqJed which is executable in Hangul Windows. The softwares LAPRoad, is develqJed to calculate luminaoce and illuminance distribution of road surlace, as well as average luminance and illuminance, overall uniformity, longitudinal uniformity, threshold increement, veilling luminance, and glare. And an apparatus that measures road surface reflection properties is developed. Because the road surlace reflection properties is very important in luminance calculation, then concrete road surlace reflection properties were measered.asered.

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