하천수 및 하수처리장 방류수의 인 제거기술

김원재,Kim, Won-Jae 한국수자원학회 2015 물과 미래(한국수자원학회지) Vol.48 No.10

메타버스 기반 뮤지엄 전시의 재매개에 관한 연구

김원재,이진우 한국박물관학회 2022 博物館學報 Vol.- No.42

This study aims to understand the audience’s experience about metaverse exhibitions. To do so, we provided the theoretical background by borrowing the concept of shedding light on museum experience (Falk & Dierking, 1992) and the theory on the interaction between media, called remediation (Bolter & Grusin 1999/2006). We, then, conducted a collective case study of “Healing Garden”, “Google Art and Culture”, and “Musee Dezentral” based on collecting data by direct observation and document review. As a result, the metaverse exhibitions contribute to offering the authenticity of experience about appreciating the exhibitions by satisfying users’ desire of immersion and reflectivity through the remediation of the offline museum exhibition. From the perspective of the dual logic of remediation, the virtual context plays a crucial role in enhancing immersion in the cases and providing differentiated features from offline museum exhibitions. Furthermore, this article discussed the construction of experience in the cases in terms of the interaction between the virtual context and the social context. By doing so, the theoretical contribution of this study lies in the conceptual understanding about the audience’s experience in the exhibition of new media through the suggestion of virtual context and the approach of remediation. 본 연구는 메타버스 기반 전시에 대한 관람객 경험의 이해를 목적으로 한다. 이에 본고는 뮤지엄 전시 경험의 이해를 위한 이론적 틀(Falk & Dierking, 1992)과 매체 간 상호작용을 논한 재매개(볼터&그루신, 1999/2006)를 이론적 배경으로 구성했다. 이후 직접관찰과 문헌검토를 통해《힐링동산》,《구글 아트 앤 컬처》,《Musee Dezentral》에 대한 집합적 사례연구를 수행했다. 연구결과, 메타버스 기반 전시는 기존 뮤지엄 전시의 재매개를 통해 사용자의 몰입과 반영에 대한 욕구를 충족시켜, 그들의 관람 경험의 진정성을 구현하고 있는 것으로 나타났다. 본 연구는 사례를 재매개의 이중 논리 안에서 포섭하여, 가상적 맥락이 메타버스 기반 전시 경험에 대한 몰입도를 제고하고, 기존 뮤지엄 전시와의 차별화된 특징을 마련하는 데 핵심 역할을 하고 있음을 확인했다. 나아가, 메타버스 기반 전시의 관람객 경험을 가상적 맥락과 사회적 맥락의 상호작용 측면에서 논하였다. 이에, 본 연구의 학술적 의의는 가상적 맥락의 제시와 재매개적 접근을 통하여 메타버스 기반 전시에 대한 관람객 경험을 개념적으로 이해한 것에 있다.

방광암 병기결정에 배설성 요로조영술의 가치

김원재,이상은,김영균 大韓泌尿器科學會 1987 Korean Journal of Urology Vol.28 No.1

한강수계 상수원 수질특성별 활성탄 및 오존/AOP 공정의 운전조건 최적화 연구

김원재,서재승,강미성,오현제,정문경,오성민 대한환경공학회 1998 대한환경공학회 학술발표논문집 Vol.1998 No.12

수질분석에 사용되는 qPCR기술

김원재,황윤정,이민혜,정민섭 한국공업화학회 2022 공업화학 Vol.33 No.3

According to the World Water Development Report 2015 released by the United Nations, drinking water is expected to decrease by 40% by 2030. This does not mean that the amount of water decreases, but rather that the water source is contaminated due to environmental pollution. Because microbes are deeply related to water quality, the analysis of microbe is very important for water quality management. While the most common method currently used for microbial analysis is microscopic examination of the shape and feature after cell culture, as the gene analysis technology advances, quantitative polymerase chain reaction (qPCR) can be applied to the microscopic microbiological analysis, and the application method has been studied. Among them, a reverse transcription (RT) step enables the analysis of RNA by RT-PCR. Integrated cell culture (ICC)-qPCR shortens the test time by using it with microbial culture analysis, and viability qPCR can reduce the false positive errors of samples collected from natural water source. Multiplex qPCR for improved throughput, and microfluidic qPCR for analysis with limited amount of sample has been developed In this paper, we introduce the case, principle and development direction of the qPCR method applied to the analysis of microorganisms.

Can We Use Single Nucleotide Polymorphism and Runt Domain Transcription Factor 3 Methylation as Tumor Markers for Bladder Cancer?

김원재,김용준 대한비뇨의학회 2009 Investigative and Clinical Urology Vol.50 No.4

Purpose: Although many tumor markers have been evaluated in relation to bladder cancer, none of these biomarkers reported to date has shown sufficient sensitivity and specificity for the detection of the whole spectrum of bladder cancer diseases in routine clinical practice. The limited value of the established prognostic markers requires analysis of new molecular parameters of interest for predicting the prognosis of bladder cancer patients. Materials and Methods: We conducted a review of the literature with a focus on recent advances in genetic polymorphism and hypermethylation events in relation to bladder transitional cell carcinoma. Results: Recently, there has been major progress in both genetic polymorphism in relation to bladder cancer and molecular genetic and epigenetic changes leading to the development of transitional cell carcinoma. However, studies on numerous single-nucleotide polymorphisms in relation to bladder cancer have provided only a few genetic polymorphisms with only marginal information on patients’ prognosis. For this reason, interest is increasing in epigenetic changes in bladder cancer. The epigenetic silencing of tumor suppressor genes is interesting from a clinical standpoint because of the possibility to reverse the epigenetic changes and thus restore gene function to a cell. Treatment with DNA methylation inhibitors can restore the activities of dormant genes and decrease the growth rate of cancer cells in a heritable fashion. Conclusions: Epigenetic modification may be possible to partially reverse the cancer phenotype, and this will eventually lead to targeted therapy tailored toward specific molecular therapy in the near future. Purpose: Although many tumor markers have been evaluated in relation to bladder cancer, none of these biomarkers reported to date has shown sufficient sensitivity and specificity for the detection of the whole spectrum of bladder cancer diseases in routine clinical practice. The limited value of the established prognostic markers requires analysis of new molecular parameters of interest for predicting the prognosis of bladder cancer patients. Materials and Methods: We conducted a review of the literature with a focus on recent advances in genetic polymorphism and hypermethylation events in relation to bladder transitional cell carcinoma. Results: Recently, there has been major progress in both genetic polymorphism in relation to bladder cancer and molecular genetic and epigenetic changes leading to the development of transitional cell carcinoma. However, studies on numerous single-nucleotide polymorphisms in relation to bladder cancer have provided only a few genetic polymorphisms with only marginal information on patients’ prognosis. For this reason, interest is increasing in epigenetic changes in bladder cancer. The epigenetic silencing of tumor suppressor genes is interesting from a clinical standpoint because of the possibility to reverse the epigenetic changes and thus restore gene function to a cell. Treatment with DNA methylation inhibitors can restore the activities of dormant genes and decrease the growth rate of cancer cells in a heritable fashion. Conclusions: Epigenetic modification may be possible to partially reverse the cancer phenotype, and this will eventually lead to targeted therapy tailored toward specific molecular therapy in the near future.

Innovative technologies for the smart E-Healthcare system

김원재,Jayoung Kim 대한비뇨의학회 2019 Investigative and Clinical Urology Vol.60 No.1

중학생이 인지하는 체육 교사의 지도유형과 라포형성 행동이 대인 신뢰와 감정반응에 미치는 영향

김원재,김준,김대열,김용은 부산대학교 과학교육연구소 2022 교사교육연구 Vol.61 No.2

본 연구의 목적은 중학생이 인지하는 체육 교사의 지도유형과 라포형성 행동이 대인 신뢰와 감정반응에 미치는 영향을 실증적으로 규명하는 것이다. 이를 위해 G광역시 소재 M중학교에 재학 중인 학생들을 대상으로 설문조사를 실시하여 271명의 유효 표본 자료를 분석에 이용하였다. 이후 가설검정을 위해 SPSS 26.0 프로그램을 이용하여 빈도분석, 탐색적 요인분석, 신뢰도분석, 다중회귀분석을 실시하였다. 이상의 과정을 통해 도출된 결과는 다음과 같다. 첫째, 지도유형의 하위요인인 교수와 지시형은 대인 신뢰의 하위요인인 정서적 신뢰에 정적인 영향을 미쳤고 민주적 행동형은 인지적 신뢰에 정적인 영향을 미쳤다. 둘째, 지도유형의 하위요인인 사회적 지지형은 감정반응의 하위요인인 긍정적 감정반응에 정적인 영향을 미쳤고 민주적 행동형은 부정적 감정반응에 부적인 영향을 미쳤다. 셋째, 라포형성 행동의 하위요인인 예의바른 행동과 정보공유 행동, 유대행동은 대인 신뢰의 하위요인인 정서적 신뢰에 정적인 영향을 미쳤고 예의바른 행동과 정보공유 행동은 인지적 신뢰에 정적인 영향을 미쳤다. 넷째, 라포형성 행동의 하위요인인 예의바른 행동과 유대행동은 감정반응의 하위요인인 긍정적 감정반응에 정적인 영향을 미쳤고 예의바른 행동은 부정적 감정반응에 부적인 영향을 미쳤다.

Wernicke’s Encephalopathy Presenting with Bilateral Complete Horizontal and Downward Gaze Palsy in a Malnourished Patient

김원재,김명미 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.4

Chloramphenicol耐性 腸티푸스菌에 對한 抗生劑의 倂合作用에 關한 硏究

金元宰,鄭在奎 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.1

Chloramphenicol(CM) 耐性腸티푸스菌에 對해서 效率的인 治療效果를 期待해서 CM과 倂合해서 抗菌作用이 亢進되는 藥劑 或은 CM과 代置할 수 있는 藥劑의 有無를 보기 위해서 試驗管內 實驗을 施行하였다. Ampicillin은 單獨으로 强한 抗菌作用을 發揮하나 CM과 倂合時는 抗菌作用의 亢進이 明白하지 않았다. kanamycin은 供試株에 對해서 單獨으로도抗菌作用이 强하며 CM과 倂合하여도 抗菌作用이 亢進되었다. Srteptomycin은 單獨으로도 感受性이 낮으며 CM과 倂合하여도 抗菌作用이 亢進되지 않았다. 그러나 ampicillin或은 kanancycin과 倂合하며는 synergistic effect를 나타내는 菌株가 있었다. Gentamicin은 장티푸스菌에 對해서는 抗菌作用이 强하지 않으나 殺菌作用이 强하며 CM과 倂合해도 抗菌 作用이 亢進되지 않았다. Kanamycin과 ampicillin이 倂合하며는 抗菌作用이 가장 亢進되었으며 CM, kanancycin 및 ampicilli의 3者倂合에서도 强한 抗菌作用이 나타나고 있다. Although the emergence of chloramphenicol(CM) resistant strains of S. typhi is rare despite of exclusive use of CM against typhoid infection, increased incidences of CM resistant strain, along with the multiple resistant strains mediated by R factors, have been reported in recent years. For the purpose to evaluate the effects of CM in combination with other antibiotcs against CM resistant S.typhi, in vitro experiments with trypticase soy broth and trypticase soy agar were carried out with 9 high CM resistant and 3 standard strains. Test strains were highly sensitive to ampicillin and moderately sensitive to kanamycin but the actions were not elevated apparently when ampicillin was combined with CM although slight additive effects were observed in some strains on trypticase soy agar, on the other hand, antibacterial action were enhanced when kanamycin was combined with CM. Gentamicin was less active to S.typhi but highly bactericidal and no enhancing effects were detected combined with CM. Streptomycin was inactive singly but when combined with either ampicillin or kanamycin exhibited a synergism against some strains. Drastic synergistic actions were observed when kanamycin was combined with ampicillin.