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정태호(Tae Ho Chung),정홍수(Hong Soo Jeong),장재권(Jae Kwon Jang),김성기(Sung Ki Kim),안종운(Jong Woon Ahn),장경호(Kyeong Ho Jang),김성록(Sung Rok Kim),오용구(Yong Gu Oh) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.4
Melanosis coli is the brownish discoloration of the colon associated with prolonged administration of anthraquinone type laxatives. The pigmentation of the colonic mucosa is due to the accumulation of lipofuscin pigment in macrophages located in the lamina propria. The diagnosis is made by endoscopy and is virtually specific for anthraquinone abuse. This is the one of the complications of laxative abuse, but the pigments disappear by withdrawing the lax- atives. We present a case of melanosis coli in a 39 year old female with histologica! Confirm by sigmoidoscopic biopsy consuming anthraquinone type laxative for 2 years. (Korean J Gas- troenterol 1994; 26: 746 750)
고유수용성신경근촉진법 이완기법이 뒤넙다리근 유연성과 점프수행력에 미치는 영향
임재헌,이민국,박종혁,정태호,조은비,Lim, Jae-Heon,Lee, Min-Kook,Park, Jong-Hyuk,Jung, Tae-Ho,Jo, Eun-Bi 대한고유수용성신경근촉진법학회 2015 PNF and Movement Vol.13 No.3
Purpose: The purpose of this study was to assess the effect of the proprioceptive neuromuscular facilitation (PNF) relaxation technique (hold relax; HR, contract relax; CR) and static stretch (SS) on hamstring flexibility and vertical jump performance in healthy adults over a four-week period. Methods: Twenty-four healthy adults volunteered to participate in PNF and static stretch sessions. The subjects were divided into three groups as follows: 8 subjects in the SS group, 8 subjects in the HR group, and 8 subjects in the CR group. In the HR and CR groups, contractions lasted 15 seconds per trial and consisted of 5 sets of 15 seconds of hamstring contraction immediately followed by 15 seconds of passive static hamstring stretching. For the static group, the participants were asked to stretch by hanging a leg over a table for 30 seconds. Subjects in all groups performed the exercises three days per week for 4 weeks. The active straight leg raising (ASLR) test, active knee extension (AKE) test, and vertical jump test were performed before the intervention and after 1, 2, and 4 weeks. Results: The SS, HR, and CR techniques effected positive improvement in hamstring flexibility and vertical jump performances but neither of the stretching methods had any statistically significant different effects according to group, although there were interactions (between group and time) in the ALSR group from 1 week to 2 week and in the AKE test from pretest to 1 week. Conclusion: Based on the results of the current study, SS, HR, and CR were shown to affect hamstring flexibility and vertical jump performance in healthy adults. In particular, it was determined that within a short period, hamstring flexibility could be attributed more to CR than to SS.
흰점박이꽃무지(Protaetia brevitarsis) 추출물의 항혈전 효능
최인학 ( In-hag Choi ),유리 ( Ri Yu ),임연지 ( Yeon-ji Lim ),최규성 ( Gyu-sung Choi ),최성업 ( Sung-up Choi ),황종익 ( Jong-ik Hwang ),손진성 ( Jin-sung Son ),정태호 ( Tae-ho Chung ) 한국환경과학회 2019 한국환경과학회지 Vol.28 No.7
We aimed to evaluate antithrombotic efficacy of Protaetia brevitarsis extract during 21 days. Rats (SPF rat, weight 240~260 g) were divided into 16 groups (5 rats per group), they were: control group and Protaetia brevitarsis extract groups with dose of 0.1, 0.5, 1, 2.5, 5, 10, 25, 50, 75, 100, 200, 250, 500, 750, 1,000 mg/kg kg of body weight. Thromboplastin time (PT) and activated partial thromboplastin time (aPPT) as antithrombotic efficacy were tested in this animal experiment (at 7, 14 and 21 days). Overall, the admistration dose of Protaetia brevitarsis extract over 50 mg/kg at 7, 14 and 21 days for PT and over 25 mg/kg at 7, 14 and 21 days for aPPT tented to be longer than that of other groups. In addition, the optimal admistration doses of Protaetia brevitarsis extract to improves antithrombotic efficacy were 75, 100, 200 and 250 mg/kg at 7, 14 and 21 days for PT (p<0.05) and 50 and 100 mg/kg at 7 days, 75 mg/kg at 14 days, or 50, 100, 200 and 250 mg/kg at 21 days for aPPT (p<0.05). It can be concluded that Protaetia brevitarsis extract at optimal levels have antithrombotic efficacy.
B형 간염바이러스의 태아와 성인간세포에 대한 감염성 해명 연구
정태호,김성국,서화정,윤영국,임종완,차상호,Chung, Tae-Ho 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2
목적 : 사람의 태아와 성인의 간세포에 B형 간염바이러스의 감염도를 비교 분석함으로써 HBV와 간세포간의 친화도내지는 HBV 수용체에 관한 정보를 얻고자 함. 대상 및 방법 : 성인이 외상을 입어 부득이 손상된 간조직을 절제하였을 경우와 모자보건법상 임신지속이 어려운 상태에서 부인과적 수술시 21주 전후의 태아 간조직을 얻어 DMEM 을 배지로 50% 용량으로 HBsAg 양성인 사람 혈청을 가하여 5일간 체외 배양하고 병리조직학적 처리후 효소면역학적 방법으로 HBsAg 를 염색하여 바이러스의 존재 여부를 검색하였다. 결과 : 태아와 성인 간조직을 5일간 체외 배양하였을 때 그 조직상은 간조직임을 인지할 수 있었다. HBV 의 감염여부는 DAKO 사의 효소면역법으로 조사한 결과 태아의 간조직에서는 HBsAg양성부위를 발견하지 못하였으나, 성인 간조직에서는 HBsAg 양성부위가 발견되었다. 결론 : 태생 21주 전후의 태아의 간세포는 HBV 와 친화도는 아주 미약하거나 없고, 성인 간세포는 HBV에 대한 친화도가 높다. 따라서 태생 21주의 간세포에는 HBV 의 감염이 어렵다는 것을 인지하게 되었다. Considerable progress has been made in the immune prophylaxis of hepatitis B virus(HBV) infection and in the understanding of its replication and pathogenecity at the molecular level. However, a convenient in vitro assay for HBV infectivity has been lacking and the early steps of viral life cycle are now yet well understood. Primary cultured human hepatocytes are reported to be susceptible to HBV 10-12, but these systems are not practical because they are short-lived and require primary explanted human liver. However, it is uncertain yet whether primary hepatocytes of human fetal liver are susceptible to HBV for infection or not. We have expanded the infectivity of HBV into a primary cultures of human fetal hepatocytes together with controversy of adult primary hepatocytes. To investigate the infectivity of HBV for adult and fetal hepatocytes After 5 day culturing fetal(1) and adult(2) liver tissues, which obtained from a surgical operation on DMEM culture media with half HBV positive serum, separating liver cells and fixing them, the existence of HBsAg antigen was investigated through the immuno-enzymatic staining. HBsAg stained area was not found in the 21 weeks gestation liver cells until 5 days of invitro-culture, while it was found in the adult liver cells. This test result showed that the HBV infection is very hard to happen in the liver cells 21 weeks gestation or prior one.
심전도 변화와 심한 혈압의 변동을 보인 갈색 세포종 1 예
장재권,김성기,장경호,정태호,정홍수,안종운,조용근,오용구 대한내과학회 1993 대한내과학회지 Vol.45 No.6
Pheochromocytoma is a surgically curable, functioning chromaffin cell tumor, causing hypertension and metabolic derangements. A 36 year old female was admitted presenting striking electrocardiographic changes mimicking ischemic heart disease and wide fluctuations of blood pressure. Coro- nary angiographic findings were normal. Urinary excretion of catecholamine and its metabolites were elevated, and pheochromocytoma was strongly suspected. Abdominal CT scan revealed a huge, round mass in the left upper abdomen. After surgical removal of the mass, the patient has become totally asymptomatic with complete disappearance of the electrocardiographic abnormalities and the fluctuations of blood pressure, and urinary excretion of catecholamines have been normalized.