http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
최의영,권혁문,윤영원,김동수,김현승 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.2
Since B-type natriuretic peptide (BNP) concentration has been shown by recent studies to be elevated in patients presenting acute coronary syndrome (ACS) even in the absence of overt heart failure, other mechanisms for elevating plasma BNP (p-BNP) concentrations may be suggested to exist. We have studied the correlation between p-BNP level and the extent of myocardial ischemia (EMI) in non-ST elevation (NSTE) ACS and evaluated the BNP level as an objective marker of EMI. In 204 patients with NSTE ACS, we estimated the EMI by the echocardiographic wall motion score index (WMSI) and the coronary angiographic Gensini score. As the positive control group, 44 patients with stable angina were enrolled into the study. We compared their initial p-BNP levels with WMSI and the Gensini score. Additionally, peak troponin-T level was compared with p-BNP level in NSTE myocardial infarction (MI) patients. Using the multiple regression analysis, adjustments for age, left ventricle (LV) wall stress, LV mass amount and ejection fraction (EF) were made. Patients with LVEF <45% or age >75 years or underlying diseases that could elevate BNP levels were excluded from the study. P-BNP level was increased in NSTE ACS patients compared with stable angina patients (133.9±87.4 vs. 12.2±9.2 pg/ml, p<0.05). P-BNP levels were found to correlate with WMSI and the Gensini score in unstable angina (r=0.519, p<0.01; r=0.680, p<0.01) and NSTEMI (r=0.716, p<0.01; r=0.684, p<0.01) patients, respectively. Additionally, p-BNP levels correlated with the peak troponin-T level in patients with NSTEMI (r=0.700, p<0.01). P-BNP level might be a useful marker in the assessment of EMI.
A Case of Pulmonary Artery Intimal Sarcoma Diagnosed with Multislice CT Scan with 3D Reconstruction
최의영,윤영원,권혁문,김동수,박병은,홍유선,구자승,김태훈,김현승 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.SUP
Pulmonary artery intimal sarcoma is a rare highly lethal disease, with additional retrograde extension to pulmonic valve and right ventricle being an extremely rare condition. It is frequently mistaken for pulmonary thromboembolism. We report a case of 64-year-old woman with progressive dyspnea initially suspected and treated for pulmonary thromboembolism. Her helical chest CT scan with 3 dimensional (3D) reconstruction combined with echocardiography revealed a compacting main pulmonary artery mass extending to the right ventricular outflow tract and the right pulmonary artery. After excision of the mass, the patient's condition improved dramatically, and the pathologic findings revealed pulmonary intimal sarcoma. This report emphasizes that helical chest CT with 3D reconstruction can be an important tool to differentiate the characteristics of pulmonary artery lesions, such as intimal sarcoma and thromboembolism.
최의영,권혁문,안철우,이근택,정보영,홍범기,윤영원,김동수,변기현,강태수,윤세정,권성우,이성주,박정관,김현승 연세대학교의과대학 2005 Yonsei medical journal Vol.46 No.1
The formation of advanced glycation end products (AGEs), in various tissues has been known to enhance immunoinflammatory reactions and local oxidant stresses in long standing diabetes. Recently, AGEs have been reported to play a role in neointimal formation in animal models of arterial injury. We attempted to determine whether the serum levels of AGEs are associated with coronary restenosis in diabetic patients. Blood samples were collected from diabetic patients with coronary artery disease undergoing stent implantation and the serum levels of AGEs were analyzed by the fluorescent intensity method. The development of in-stent restenosis (ISR) was evaluated by a 6-month follow-up coronary angiography. A total of 263 target lesions were evaluated, in 203 patients. The ISR rate in the high-AGE (>170U/ml) group (40.1%) was significantly higher than in the low-AGE group (≤170 U/ml) (19.6%) (p<0.001). Furthermore, multivariate analysis revealed that a high level of serum AGEs is an independent risk factor for the development of ISR (odds ratio, 2.659; 95% CI, 1.431-4.940; p=0.002). The serum levels of AGEs constitute an excellent predictive factor for ISR, and should be one of the guidelines for medical therapy and interventional strategy to prevent ISR in diabetic patients.
崔義永 건국대학교 1982 論文集 Vol.15 No.1
The idea of European Integration was already originated in the 14th century, but it had been nothing but an ideal and unreal pursuit untill the 20th century, in which real pursuit for integration has been activated. Many politians and thinkers have been interested in presenting their theories of integration. Some represent active people of them are Henry IV, Sully, Saint Saimon, Proudhon, Kalergi, Briand and Schuman. Western Europe began to see their economic failure and collapse of political order during the two world warts, and lost their dominant position in the world. And from that time on their have been struggling between the two powers, the United States and Russia. This unexpected downfall was realy disgraceful to their gloriousness in the past. They looted back upon internal and external accidents which had brought about their downfall, and self-examined their causes. And they had to united and spurt together in order to regain the glorious position of the past. Doing this, they have found a natural motivation in searching for a substantial European Integration. EEC was activited as an effort to achieve European Integration, just as ECSC, EDC, EPC, etc., but much more concret and substantial expression, EEC, although motivated as an economic integration in the begining, but in the light of its aim of set-up, common politics and process of working, was a step for its final object of achiving a political integration and securing an advanced position in the world economy, EEC has, on the one hand, carried on steadily its partial with some fruitful outcome. But, on the other hand, it has not progressed to much in the problems requiring political agreements. Therefore, today's EEC has come to limitation in which situation more development cannot be expected without political agreements. In addition, it has many difficulties in the way of approaching 1980's, such as internal conflicts, external initiative enhancement, relation which the U.S. some required agreements in the admission of England, including the energy crisis. Some chief elements blocking European Integration are utility diplomacy of each stats, lack of necessary external stimulus, delay in settling the problems causes when a new member centers, and so on. In this respect, it is highly desired that European try to develop EEC, by settling such obstacles, in more affirmative aspects rather than negative ones, in which the only possible way would be to break up, for more successful achievement of European Interation. They rather should do this, if they want to live on as they like to, in today's world Situation. In other words, Europeans, any way, have contributed to achieving of settling new problems, maximizing spilt-over effects, through their common participation in developing EEC, it can be staid with assurance that European Integration will be carried on favorably.