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      • KCI등재후보

        Correlations Between Fasciology and Yin Yang Doctrine

        Hui Tao,Mei-chun Yu,Hui-ying Yang,Rong-mei Qu,Chun Yang,Xin Zhou,Yu Bai,Jing-peng Wu,Jun Wang,Ou Sha,Lin Yuan 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.2

        The aim of this study is to explore the correlations between fasciology and yin yang doctrine. Professor Yuan developed fasciology by three-dimensional reconstruction of connective tissue (fascia) in the trunk and limbs of the human body and tracing back to tissue origins in light of biological evolution and developmental biology. Fasciology states that the human body can be divided into two systems: the supporting-storing system and the functional system. This article elaborates on the roles of the two systems and their mutual relationship. The two systems are used to analyze the yin,the yang, and their relationship. The two systems are promoted but also restricted in different contexts. The supporting-storing system is formed by undifferentiated connective tissue and provides undifferentiated cells and nutrients for differentiated cells of the functional system. Thus, the supporting-storing system could be classified as quiet, similar to yin. The functional system continuously maintains the various functional activities of the human body. Thus, the functional system could be classified as active, similar to yang. In interpreting the yin yang doctrine from the point of view of fasciology, yin can be compared with the supporting-storing system and yang can be compared with the functional system.

      • KCI등재

        Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging

        Huan-Huan Chen,Hao Hu,Wen Chen,Dai Cui,Xiao-Quan Xu,Fei-Yun Wu,Tao Yang 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.3

        Objective: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients with thyroidassociated orbitopathy (TAO) as well as in evaluating disease activity. Materials and Methods: We enrolled 35 TAO patients and 22 healthy controls (HCs) who underwent pre-treatment rs-EPIbased DTI. Mean, axial, and radial diffusivity (MD, AD, and RD) and fractional anisotropy (FA) of the medial and lateral EOMs and optic nerve for each orbit were calculated and compared between TAO and HC groups and between active and inactive TAO groups. Factors such as age, sex, disease duration, mediation, and smoking history between groups were also compared. Logistic regression analysis was used to evaluate the predictive value of significant variables for disease activity. Results: Disease duration was significantly shorter in active TAOs than in inactive ones (p < 0.001). TAO patients showed significantly lower FA and higher MD, AD, and RD than HCs for both medial and lateral EOMs (p < 0.001), but not the AD value of lateral EOMs (p = 0.619). Active patients had significantly higher FA, MD, and AD than inactive patients for medial EOMs (p < 0.005), whereas only FA differed significantly in the lateral EOMs (p = 0.018). The MD, AD, and RD of optic nerves were significantly lower in TAO patients than HCs (p < 0.05), except for FA (p = 0.129). Multivariate analysis showed that the MD of medial EOMs and disease duration were significant predictors for disease activity. The combination of these two parameters showed optimal diagnostic efficiency for disease activity (area under the curve, 0.855; sensitivity, 68.4%; specificity, 96.9%). Conclusion: rs-EPI-based DTI is promising in assessing microstructural changes of EOMs and optic nerves and can help to indicate the disease activity of TAO, especially through the MD of medial EOMs.

      • Reliability Analysis and Prediction for Product Design Based on Feature Similarity

        Tao Yang,Yu Yang,Yao Jiao 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.5

        During product design phase, aiming at the problem of lacking reliability data, lower of product reliability, feature similarity-based new product design reliability analysis and prediction model were proposed. Putting the new product features as an evaluation objectives, an approach named Technique for Order Preference by Similarity to Ideal Solution(TOPSIS) was established firstly for selecting similar features products; Then, in order to realize the reliability analysis relational mapping with the new product design, the failure structure of the similar features products was quantified and the product failure structure matrix (FSM) was established, respectively; Afterwards, the Group Decision Making Method (GDMM) was presented for determining the improvement factor of the similar features products failure causes, on that basis, the new product features failure structure was generated to predict the reliability of new designing products. Finally, feasibility and effectiveness of the model were verified through an example of new Smart Mobile Phone product design.

      • KCI등재

        Purification and Structure Analysis of Mycolic Acids in Corynebacterium glutamicum

        Yang Yang,Feng Shi,Guanjun Tao,Xiaoyuan Wang 한국미생물학회 2012 The journal of microbiology Vol.50 No.2

        Corynebacterium glutamicum is widely used for producing amino acids. Mycolic acids, the major components in the cell wall of C. glutamicum might be closely related to the secretion of amino acids. In this study, mycolic acids were extracted from 5 strains of C. glutamicum, including ATCC 13032,ATCC 13869, ATCC 14067, L-isoleucine producing strain IWJ-1, and L-valine producing strain VWJ-1. Structures of these mycolic acids were analyzed using thin layer chromatography and electrospray ionization mass spectrometry. More than twenty molecular species of mycolic acid were observed in all 5 strains. They differ in the length (20–40carbons) and saturation (0–3 double bonds) of their constituent fatty acids. The dominant species of mycolic acid in every strain was different, but their two hydrocarbon chains were similar in length (14–18 carbons), and the meromycolate chain usually contained double bonds. As the growth temperature of cells increased from 30°C to 34°C, the proportion of mycolic acid species containing unsaturated and shorter hydrocarbon chains increased. These results provide new information on mycolic acids in C. glutamicum,and could be useful for modifying the cell wall to increase the production of amino acids.

      • Experimental Study on Inhibition Effects of the XAF1 Gene against Lung Cancer Cell Proliferation

        Yang, Wen-Tao,Chen, Dong-Lai,Zhang, Fu-Quan,Xia, Ying-Chen,Zhu, Rong-Ying,Zhou, Duan-Shan,Chen, Yong-Bing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

        Objective: To investigate the effect of high expression of XAF1 in vivo or in vitro on lung cancer cell growth and apoptosis. Methods: 1. The A549 human lung cancer cell line was transfected with Ad5/F35 - XAF1, or Ad5/F35 - Null at the same multiplicity of infection (MOI); (hereinafter referred to as transient transfected cell strain); XAF1 gene mRNA and protein expression was detected by reverse transcription polymerase chain reaction (RT-PCR) and Western blotting respectively. 2. Methyl thiazolyl tetrazolium (MTT) and annexin V-FITC/PI double staining were used to detect cell proliferation and apoptosis before and after infection of Ad5/F35 - XAF1 with Western blotting for apoptosis related proteins, caspase 3, caspase - 8 and PARP. 3. After the XAF1 gene was transfected into lung cancer A549 cells by lentiviral vectors, and selected by screening with Blasticidin, reverse transcription polymerase chain reaction (RT-PCR) and Western blotting were applied to detect mRNA and protein expression, to establish a line with a stable high expression of XAF1 (hereinafter referred to as stable expression cell strain). Twenty nude mice were randomly divided into groups A and B, 10 in each group: A549/XAF1 stable expression cell strain was subcutaneously injected in group A, and A549/Ctrl stable cell line stable expression cell strain in group B (control group), to observe transplanted tumor growth in nude mice. Results: The mRNA and protein expression of XAF1 in A549 cells transfected by Ad5/F35 - XAF1 was significantly higher than in the control group. XAF1 mediated by adenovirus vector demonstrated a dose dependent inhibition of lung cancer cell proliferation and induction of apoptosis. This was accompanied by cleavage of caspase -3, -8, -9 and PARP, suggesting activation of intrinsic or extrinsic apoptotic pathways. A cell strain of lung cancer highly expressing XAF1 was established, and this demonstrated delayed tumor growth after transplantation in vivo. Conclusion: Adenovirus mediated XAF1 gene expression could inhibit proliferation and induce apoptosis in lung cancer cells in vitro; highly stable expression of XAF1 could also significantly inhibit the growth of transplanted tumors in nude mouse, with no obvious adverse reactions observed. Therefore, the XAF1 gene could become a new target for lung cancer treatment.

      • KCI등재

        Design of a MEMS sensor array for dam subsidence monitoring based on dual-sensor cooperative measurements

        ( Tao Tao ),( Jianfeng Yang ),( Wei Wei ),( Marcin Woźniak ),( Rafał Scherer ),( Robertas Damaševičius ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.10

        With the rapid development of the Chinese water project, the safety monitoring of dams is urgently needed. Many drawbacks exist in dams, such as high monitoring costs, a limited equipment service life, long-term monitoring difficulties. MEMS sensors have the advantages of low cost, high precision, easy installation, and simplicity, so they have broad application prospects in engineering measurements. This paper designs intelligent monitoring based on the collaborative measurement of dual MEMS sensors. The system first determines the endpoint coordinates of the sensor array by the coordinate transformation relationship in the monitoring system and then obtains the dam settlement according to the endpoint coordinates. Next, this paper proposes a dual-MEMS sensor collaborative measurement algorithm that builds a mathematical model of the dual-sensor measurement. The monitoring system realizes mutual compensation between sensor measurement data by calculating the motion constraint matrix between the two sensors. Compared with the single-sensor measurement, the dual-sensor measurement algorithm is more accurate and can improve the reliability of long-term monitoring data. Finally, the experimental results show that the dam subsidence monitoring system proposed in this paper fully meets the engineering monitoring accuracy needs, and the dual-sensor collaborative measurement system is more stable than the single-sensor monitoring system.

      • Chaotic secure communication systems : History and new results

        Tao Yang 에스케이텔레콤 (주) 1999 Telecommunications Review Vol.9 No.4

        Secure communication using synchronization between chaotic systems(chaotic secure communication, for short) is a new concept of secure communication. The great potentials of this kind of ''hardware key'' secure communication systems had driven the progress of this field rapidly. Since 1992, chaotic secure communication has evolved four generations. In this paper, a detailed history of chaotic secure communication systems is given. The disadvantage of the first three generations of chaotic secure communication schemes is low efficiency of channel usage. To overcome this disadvantage, a chaotic communication scheme, which belongs to the fourth generation, using impulsive synchronization of chaotic systems is presented. In this paper, impulsive synchronization of two chaotic systems is reformulated as impulsive stabilization of a synchronization error system to the origin. Based on the theory of impulsive differential equations, we present theoretical results on the asymptotic synchronization of two chaotic systems by using synchronization impulses. An estimate of the upper bound of impulse interval is given for the purpose of asymptotic synchronization. The robustness of impulsive synchronization to additive channel noise and parameter mismatch is also studied. We conclude that impulsive synchronization is robuster than continuous synchronization. Combining both conventional cryptographic method and impulsive synchronization of chaotic systems, we propose a new chaotic secure communication scheme. We use this new chaotic secure communication scheme to transmit a speech signal. Computer simulation results based on Chua's oscillators are given.

      • KCI등재

        High performance KNN-based single crystal thick film for ultrasound application

        Tao Zhang,Jun Ou-Yang,Xiaofei Yang,Wei Wei,Benpeng Zhu 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.1

        Using a novel lapping technology, the achievement of approximately 28 μm (K 0.45 Na 0.55 ) 0.96 Li 0.04 NbO 3 (abbreviated asKNLN) single crystal thick fi lm with <001> orientation has been realized. This kind of thick fi lm exhibited excellent electricalperformance: a superior piezoelectric constant (~ 490 pm/V) and an outstanding electromechanical coupling coeffi cient(k t ~ 0.55). Based on the obtained KNLN single crystal thick fi lm, a tiny side-looking 82 MHz ultrasound transducer witha bandwidth of 57.3% at − 6 dB has been successfully fabricated. Most importantly, 80 MHz intravascular ultrasound andphotoacoustic images of the healthy rabbit aorta have been presented. All these promising results indicate that KNN-basedsingle crystal thick fi lm is a good environmental protection candidate for high frequency (~ 80 MHz) ultrasound applications.

      • KCI등재

        Mitochondrial citrate accumulation drives alveolar epithelial cell necroptosis in lipopolysaccharide-induced acute lung injury

        Yang Hui-Hui,Jiang Hui-Ling,Tao Jia-Hao,Zhang Chen-Yu,Xiong Jian-Bing,Yang Jin-Tong,Liu Yu-Biao,Zhong Wen-Jing,Guan Xin-Xin,Duan Jia-Xi,Zhang Yan-Feng,Liu Shao-Kun,Jiang Jian-Xin,Zhou Yong,Guan Cha-Xi 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Necroptosis is the major cause of death in alveolar epithelial cells (AECs) during acute lung injury (ALI). Here, we report a previously unrecognized mechanism for necroptosis. We found an accumulation of mitochondrial citrate (citratemt) in lipopolysaccharide (LPS)-treated AECs because of the downregulation of Idh3α and citrate carrier (CIC, also known as Slc25a1). shRNA- or inhibitor–mediated inhibition of Idh3α and Slc25a1 induced citratemt accumulation and necroptosis in vitro. Mice with AEC-specific Idh3α and Slc25a1 deficiency exhibited exacerbated lung injury and AEC necroptosis. Interestingly, the overexpression of Idh3α and Slc25a1 decreased citratemt levels and rescued AECs from necroptosis. Mechanistically, citratemt accumulation induced mitochondrial fission and excessive mitophagy in AECs. Furthermore, citratemt directly interacted with FUN14 domain-containing protein 1 (FUNDC1) and promoted the interaction of FUNDC1 with dynamin-related protein 1 (DRP1), leading to excessive mitophagy-mediated necroptosis and thereby initiating and promoting ALI. Importantly, necroptosis induced by citratemt accumulation was inhibited in FUNDC1-knockout AECs. We show that citratemt accumulation is a novel target for protection against ALI involving necroptosis.

      • KCI등재

        Application of Acoustical Method to Characterize Nonwoven Material

        Tao Yang,Xiaoman Xiong,Yuanfeng Wang,Rajesh Mishra,Michal Petrů,Jiří Militký 한국섬유공학회 2021 Fibers and polymers Vol.22 No.3

        Some structural parameters, such as tortuosity, viscous and thermal characteristic lengths, are difficult to obtainthrough direct measurements. Existing indirect methods, i.e. acoustical method, make it possible to estimate theseparameters. This paper presents an application of acoustical inversion methods for estimating structural parameters ofpolyester nonwoven materials. A four-microphone impedance tube was used to measure sound reflection and transmissioncoefficients. The inversion methods used in this research are least square and Bayesian approaches. The least square methodwas achieved via Nelder-Mead algorithm. The Bayesian inversion process was conducted with Metropolis-Hastingsalgorithm and maximum a posteriori. Inversed parameters from two methods as well as front and back sides of nonwovenfabric were compared. Moreover, inversed porosity and airflow resistivity were compared with measured values. The resultsshow that the least square and Bayesian methods has a good agreement. Estimated parameters from Bayesian method wereselected for further analysis. A sizable differences on thermal characteristic length were found by comparing the values fromtwo sides, while the differences are relatively small for other parameters. It is also found that the inversed porosity, tortuosityare reasonable. The results suggest that the acoustical inversion methods can be used to accurately characterize polyesterfibrous materials.

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