재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.

6개원소로 이루어진 짝이중결합화합물과 AsCl_3와의 반응

주완철,육명화,김용주 成均館大學校 科學技術硏究所 1983 論文集 Vol.34 No.2

6개의 원소로 이루어진 오르토히드록시짝이중결합화합물, 즉 시남알데히드-오르토-히드록시아닐(cinnam-aldehyde-ortho-hydroxyanil), 벤질모노히드록시아닐(benzil-mono-hydroxyanil), 오르토-히드록시벤잘아세톤페논(ortho-hydroxy benzalacetophenone)과 알진트리클로라이드(AsCI_3)와의 반응으로부터 고체반응생성물을 분리해 냈다. 이들 반응생성물의 적외선 및 자외선분광학으로부터, 이들 모든 반응생성물은 비소의 전하이동착물임을 획인했다. 이 반응으로부터 3원자가 비소화합물의 화학적거동이 인의 3원자가 화합물과 유사하지 않다는 것을 알 수 있었다. Solid products were isolated by the reaction of orthohydroxy-6-membered conjugated system such as cinnamaldehyde-ortho-hydroxyanil, benzil-mono-orthohydroxyanil and ortho-hydroxybenzalacetophenon with AsCl_3. All of these products were confirmed to be Charge-transfer complexes of As from the examination of IR and UV spectra. It could be found that the chemical behavior of trivalent As is not analogous with that of triv alent P.

갑상선 종양에서 thrombin receptor (PAR-1)의 발현 양상

박지영,목지오,김여주,박형규,김철희,변동원,서교일,유명희,조현득,오미혜,김상진 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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현훈 환자 Neuron Specific Enolase의 임상적 의의

김원주,김선곤,유철형,김원찬,김용덕,최영철,이명식 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

1-Silacyclopentadiene으로부터 Silylene을 합성하는데 대한 연구

공영건,주완철 成均館大學校 科學技術硏究所 1983 論文集 Vol.34 No.1

1-Spiro(tetraphenyl-1-silacyclopentadiene) was obtained from the reaction of 1, 2, 3, 4-tetraphenylbutadiene anion with tetrachlorosilane in ether. This spiro compound is treated with phenylacetylene at 350℃ in sealed tube. From this reaction, pentaphenylbenzene and polymer like silicon compound which are byproducts of silylene formation, are isolated. The reaction product which must be formed from the reaction of silylene and phenylacetylene, is now under investigation.

하경추부 손상환자에 대한 임상적 분석

박영록,홍순기,허철,김헌주,한용표 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.6

The authors analyzed 32 cases with lower cervical spine injuries according to their etiologies, the findings of cervical spine X-ray and computed tomography, initial neurological grading scales and time of operation. The results are summarized as follow : 1) Lower cervical spine injuries occurred in 32 of the 49 cervical spine injuried patients. 2) The important factors affecting on outcome were the initial neurological state(p=0.038) and the degree of spinal canal narrowing on cervical computed tomogram(p=0.046). 3) The degree of prevertebral soft tissue swelling and displacement of vertebral body on initial cervical spine X-ray did not significantly affect on outcome(p=0.052). 4) The most suitable operative time for lower cervical spine injuries was 10∼20 days after injuries and the mortality was 9.3%.

2세대 Metal-on-Metal Prosthesis를 사용한무시멘트 인공 고관절 전치환술 중간 결과 보고 (5-10년)

김영창,정경칠,곽희철,김주용 대한고관절학회 2004 Hip and Pelvis Vol.16 No.1

만성 정신분열병 환자에서 지연성 운동장애와 음성증상 및 인지기능 장애와의 연관성

심주철,반철식,성기수,이정구,정도운,정청,윤진상,김영훈 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: 정신과 전문병원에 입원해 있는 만성정신분열병 환자들을 대상으로 첫째 지연성 운동장애의 유병율과 위험인자들을 조사하고, 둘째 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성을 조사하고자 한다. 방법: 연구대상자는 마산동서병원에 입원 중인 환자 중 DSM-IV의 정신분열별 진단기준에 부합하며, 최근 3개월 이상 동일 용량의 항정신병약물 복용한 271명(남자 174명, 여자 97명)의 환자들이었다. 지연성 운동장애에 대한 평가는 Abnormal Involuntary Movement Scale(AIMS)을 이용하였고, DSM-IV와 Sc-hooler와 Kane(1982)의 진단기준 양자에 부합하는 환자들만을 지연성 운동장애군으로 분류하였다, 정신 분열병 정신병리에 대한 평가는 Brief Psychiatric Rating Scale(BPRS)와 Schedule for the Deficit Syndrome(SDS)을 이용하였고, 인지기능에 대한 평가는 Mini-Mental Status Examination(MMSE)을 이용하였다. 결과: 지연성 운동장애의 유병율은 50.9%이었고, 50세 이상, 남자에서 높았다. 그러나 입원기간과 항정신병 약물의 일일 사용량에 따른 차이는 없었다. 지연성 운동장애의 호발부위는 혀, 상지, 입술과 입 주위의 순이었다. BPRS 총점 및 소항목 척도점수와 SDS 척도점수는 지연성 운동장애의 유무에 따른 차이가 없었다. MMSE 총점 및 소항목 점수도 지연성 운동장애의 유무에 따른 차이가 없었다. 결론: 평균입원기간이 9년 이상인 만성정신분열병 환자들에게서의 지연성 운동장애의 유병율은 50.5%이었고, 연령이 가장 의미있는 위험인자임을 확인했다. 만성정신분열병 환자들이 주 대상인 본 연구에서는 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성은 입증하지 못했다. Objectives: The purpose of present study was to determine the prevalence rate of tardive dyskinesia and to search for its risk factors in chronically institutionalized schizophrenic subjects. We also examined the relationship between tardive dyskinesia and both negative symptoms and cognitive impairments in the same subjects. Methods: Subjects were 271 in-patients(174 males, 97 females) at Masan Dongsuh Hospital. They met DSM-IV criteria for schizophrenia and had been taking fixed doses of antipsychotics for at least 3 months. Tardive dyskinesia was assessed by Abnormal Involuntary Movement Scale(AIMS). Cases of tardive dyskinesia were ascertained by the criteria of Schooler and Kane (1982) and DSM-IV. The rating of psychopathology was acquired using Brief Psychiatric Rating Scale(BPRS) and Schedule for the Deficit Syndrome(SDS) and the assessment of cognitive function using Mini-Mental State Examination(MMSE). Results: The prevalence of tardive dyskinesia is 50.9% and the frequency of tardive dyskinesia was high est in male above the age of fifty. But there was no statistically significant relationship between the frequency of tardive dyskinesia and both the length of hospitalization and the daily dose of antipsychotics. The frequency order of abnormal movement in the patients with tardive dyskinesia was as follows : tongue, upper extremities, lips and perioral area. We couldn't find any significant difference in the total and subscale scores of BPRS between the groups with and without tardive dyskinesia. There were no differences in MMSE scores between the groups with and without tardive dyskinesia. Conclusion: This study gave us that the prevalence of tardive dyskinesia was high in chronically institutionalized schizophrenic inpatients and that age was the most significant risk factor of tardive dyskinesia. The relationship between tardive dyskinesia and both negative symptoms and cognitive impairment, however, was not revealed.

수직냉각면을 가진 함수정방형내에서 초기온도가 동결량에 미치는 영향에 관한 실험적 연구

김병철,주동인,손정배,박영훈 조선대학교 에너지.자원신기술연구소 1997 에너지·자원신기술연구소 논문지 Vol.19 No.2

The effect of initial temperature on freezing with vertical cold wall in rectangular cavity was studied. When the initial temperature was below the 4℃, the frozen thickness in the upper part was thicker than that of lower part from the beginning of freezing and above the 4℃, at beginning the frozen thickness in the upper part was thinner than that of lower part but with time the frozen thickness in the upper part was thicker than that of lower part. And when it was above the 8℃, at the beginning of freezing the upper part of frozen thickness was thinner than that of lower part with concave but with time the concave in the upper part became thicker and the frozen thickness in the upper part was thicker than that of lower part too. The effect of initial temperature had no effect on the increasing of ice volume with time because in the beginning of freezing the more initial temperature was low, the more frozen thickness grew but the heat resistance increased in proportion as the frozen thickness grew.

一部 鍍金作業者의 淋巴球 姉妹染色分體交換 出現에 關한 硏究

崔榮珠,金永煥,車喆煥 고려대학교 의과대학 1987 고려대 의대 잡지 Vol.24 No.1

Since the sister chromatid exchange(SCE) technique was developed by Taylor in 1958, it has been modified and utilized in the fields of mutagenicity, teratogenicity and carcinogenicity evaluation not only for academic purpose but also occupational medicine. In Korea, however, very rare approaches to mutagenicity of toxic agents were performed. And no research on SCE in human lymphocytes was reported in relation to occupational working environment up to date in Korea. Therefore this study was designed to know the possibility of utilizing the SCE as an index which could evaluate the effect of toxic chemicals on the health of industrial workers. A total of 32 metal plating workers using chromium which was proved having mutagenicity and carcinogenicity were selected as an experimental group for this studies. The SCE in peripheral lymphocytes of the workers was studied including the amount of chromium excretion in urine, the smoking amount and working years. The results were as follows; 1. The average number of SCE per lymphocyte was significantly higher in plating workers than nonexposure group showing the rate of 1.6 (5.7 v/s 3.6). 2. The difference in SCE status by smoking habit was not statistically significant both in exposure and unexposure groups. There was no difference in SCE status by career of exposed workers. 3. The higher the concentration of chromium in working environment, the higher the number of SCE per lymphocyte in exposed workers was showed, which revealed a clear dose-response relationship. 4. The correlation between number of SCE per cell and amount of chromium in urine was statistically significant with the coefficient of 0.661 showing Y= 0.23X + 3.0 (P<0.01), in which Y indicates number of SCE per cell and X indicates chromium concentration in urine by ㎍/1.