국가예방접종전산등록체계 개발을 위한 민간의료 기관 하부구조 및 환경 조사연구

이무식,김은영,이건세,이석구,홍지영,김건엽,김대경,신의철,이연경,기몽서,나백주,김영택 한국모자보건학회 2003 한국모자보건학회지 Vol.7 No.2

Microstructure and properties of cross-roll rolled and heat treated metastable TiNbSn alloy.

Jung, Taek-Kyun,Choi, Ho-Joon,Kim, Kyung-Taek,Shin, Young-Chul,Lee, Hyo-Soo,Lim, Sung-Chul,Kwon, Hyouk-Chon,Hanada, Shuji American Scientific Publishers 2014 Journal of nanoscience and nanotechnology Vol.14 No.10

<P>A (Ti-35mass%Nb)-4mass%Sn alloy was cross-roll rolled with a reduction ratio of 70% in which the roll axes are tilted by 5 degrees away from the transverse direction of the rolled sample and then aged at 250 degrees C for 2 h. Cross-roll rolling was found to increase yield strength and Young's modulus, simultaneously. Yield strength was higher in cross-roll rolled than in conventionally rolled at same reduction ratio. Yield and tensile strength further increased by a low temperature ageing by ψ precipitation hardening and microstructure refinement. Yield and tensile strength of the aged 70% cross-roll rolled sample were higher than those of the aged 70% conventionally rolled one.</P>

그레이브스병에서 치료에 따른 폐동맥압의 변화

남택만,조한수,이진서,송영림,김두만,두영철,박철영,정인경,홍은경,이성진,오기원,김현규,유재명,최문기,유형준,박성우 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.5

연구배경: 갑상선기능항진증에 의한 갑상선중독증 환자들은 호흡곤란을 호소하며, 그 원인으로 호흡근의 근력 약화, 좌심실부전으로 인한 폐모세혈관의 울혈, 기도저항의 증가, 갑상선종으로 인한 기관의 압박, 호흡기능 이상 등이 거론되고 있다. 폐동맥고혈압이 동반된 그레이브스병 환자가 여러 증례가 보고되었으며, 폐동맥고혈압 환자에게서 갑상선 자가항체와 갑상선기능저하증의 빈도가 높음이 알려지면서 갑상선중독증이 동반된 그레이브스병 환자에게서 관찰되는 호흡곤란의 한 원인으로 폐동맥압 증가가 작용할 가능성이 제시되고 있다. 이에 저자 등은 그레이브스병 환자를 대상으로 폐동맥압을 측정하고 치료 전후의 폐동맥압의 변화를 전향적으로 연구하였다. 방법: 갑상선중독증이 동반된 그레이브스병 환자와 정상 갑상선기능을 나타낸 대조군을 대상으로 갑상선기능검사 및 갑상선 자가항체를 측정하고, 심초음파를 이용하여 치료 전후로 폐동맥압을 측정하여 폐동맥압과 갑상선기능 및 갑상선 자가항체와의 관계, 폐동맥압의 변화 등을 관찰하였다. 결과: 1. 연구대상은 대조군 10명 (남녀비 1:9, 관해 상태의 그레이브스병 3명, 갑상선종 3명, 정상인 4명), 그레이브스병 환자 26명 (남녀비 7:19)이었다. 2. 대조군과 치료 전 그레이브스병 환자의 폐동맥압은 각각 23.5±2.32 mmHg, 29.6±10.3 mmHg이었고, 치료 전의 폐동맥압과 혈청 갑상선자극호르몬 결합억제 면역글로불린 (TBII) 농도는 유의한 양의 상관관계를 보였다. 3. 26명의 그레이브스병 환자 중에서 10명 (38.5%)이 폐동맥고혈압 (기준: 폐동맥압 > 30 mmHg)으로 진단되었다. 4. 치료 전후로 폐동맥압을 측정한 13명은 폐동맥압이 치료 전 29.6±10.3 mmHg에서 치료 후 폐동맥압 22.2±6.48 mmHg로 의미있게 감소하였다. 결론: 갑상선중독증을 보이는 그레이브스병 환자의 약 40% 정도에서 폐동맥고혈압이 발견되어 폐동맥고 혈압은 그레이브스병에 흔하게 동반하는 질환으로 생각된다. 향후 그레이브스병 환자에서 관찰되는 폐동맥압의 증가와 관련한 병인, 발생기전 및 임상적 의의 등에 대한 연구가 필요할 것으로 생각된다. Background: Exertional symptoms, dyspnea and impaired effort tolerance are common in patients with Graves' disease. Proposed explanations include: high-output left heart failure, ineffective oxygen utilization and respiratory muscle weakness. In addition, pulmonary hypertension has also been reported in patients with Graves' disease. A high prevalence of hypothyroidism and positive thyroid autoantibody were also observed in patients with pulmonary arterial hypertension. Therefore, the pulmonary artery pressure in patients with Graves' disease was evaluated. Methods: Two-dimensional and Doppler echocardiographic examinations (Hewlett Packard Sonos 2500) were performed to determine the pulmonary artery (PA) pressure in 26 Graves' disease patients, both before and after treatment (23 patients with propylthiouracil and 3 with RAI), and in 10 euthyroid controls. The changes in the PA pressure after treatment were evaluated in 13 patients with Graves' disease, who became euthyroid after treatment. Results: The pulmonary artery pressure was increased in the untreated Graves' disease patients compared to the normal controls (23.5±2.32 vs. 29.6±10.3 mmHg). 38.5% of the Graves' disease patients (10/26) showed pulmonary arterial hypertension (PA>30 mmHg) and the serum TBII level was higher in the Graves' disease patients with pulmonary arterial hypertension than in those with normal PA pressure (P<0.05). In the Graves' patients who became euthyroid after treatment, the PA pressure was significantly decreased. Conclusion: 38.5% of the untreated Graves' disease patients showed pulmonary arterial hypertension, and the pulmonary artery pressure was significantly decreased in those who became euthyroid after treatment. The pathogenesis and clinical importance of pulmonary arterial hypertension in Graves' disease requires further studies (J Kor Soc Endocrinol 18:465∼472, 2003).

수입각증후군에 의한 급성 복증 1례

정은욱,지삼룡,이영태,박지훈,김동기,제인수,채두근,박성재,박은택,이연재,이상혁,설상영,정정명 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Afferent loop syndrome is an uncommon complication of a gastrectomy and Billroth Ⅱ reconstruction. It may cause symtoms at any time from the first postoperative day to many years after the gastrectomy. Afferent loop syndrome is characterized by abdominal pain, vomiting and elevation of serum amylase. Thus, it is difficult to differentiate afferent loop syndrome from other cause of acute pancreatitis. However, the history of gastrectomy can be an important clue for diagnosing afferent loop syndrome. We experienced one case of chronic afferent loop syndrome with acute pancreatitis. After appropriate management, the abdominal pain disappeared and serum amylase level decreased. We report this case with a review of relevant literatures.

바터 팽대부에 생긴 유암종 1예

강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

용치놀래기, Halicoeres poesilopterus(Temmink et Schlegel) 生殖生態

李榮敦,李澤烈,盧洪吉 濟州大學校海洋硏究所 1991 해양과환경연구소 연구논문집 Vol.15 No.-

1990년 10월부터 1991년 9월까지 제주도 북방함덕연안에서 채집된 용치놀래기, Halicoeres poecilopterus를 대상으로 生殖生態를 파악하기 위하여 生殖巢熟度指數(GSI)와 生殖巢의 組織學的 방법에 의한 生殖週期와 性轉換 과정 등을 조사한 결과는 다음과 같다. 1. 生殖巢熟度指數(GSI)는 암 수 다같이 6월에 급겨히 상승하여 7월에 최대치를 나타내고 있으며, 8월에 접어들면서 하강하기 시작하여 9월부터 낮은 값을 나타내고 있다. GSI최대값은 암컷 6.35 수컷 1.01을 나타냈다. 2. 生殖週期는 성장기(5∼6월), 성숙기(6∼7월), 완숙 및 산란기(7∼8), 회복 및 휴지기(8∼4월)등의 연속적인 주기를 나타냈다. 3. 체장 13.0∼15.0㎝되는 개체들에서 雌性에서 雄性으로 性轉換現像이나타났다. 4. 본종은 一次精巢와 二次精巢가 혼합되어 나타나는 複雄性(diandry)의 雌性先熟魚에 속하는 것으로 나타났다. 5. 암컷에서 수컷으로 性轉換함에 따라 적색에서 청색으로 채색변화가 나타나고 있다. Reproductive ecology of the Wrasse, Halicoeres poecilopterus was investigated histologically on the gonadal development, sex reversal and studied by gonadosomatic index(GSI), color patterns. Samples were collected at the costal area of Ham duck, Cheju-do, Korea from October, 1990 to September, 1991. In male and female, GSI began to increase from june when the water temperature began to increase and the reached maximum value in July, respectively. It began to decrease from August. Thereafter, maintained relatively low value until May of next year. The annual reproductive cycle of this species could be classified into four sucessive developmental stage : growing stage(May), mature stage(June-july), ripe and spent stage(July-August), degenerative and resting stage(August-April). In H.poecilopterus, individuals with hermaphroditic gonad were observed in 13.0-15.0㎝ in standard length. sex reversal of this species could be oceured from 13.0㎝ to 15.0㎝ in standard length. A(red) and B(blue) types of color patterns were observes in this species. The individuals in plain A type coloration are mainly females and hermaphroditic individuals, but few primary and secondary males are included. The individuals in gaudy B type coloration are mostly secondary and primary males.

양수가 대수층의 오염물질 이동에 미치는 영향

李永東,洪熙澤 全北大學校 1996 論文集 Vol.42 No.-

Transport of pollutants in a groundwater flow system is accomplished by the simultaneous action of four processes : advection, dispersion, molecular diffusion, and hydregeochemical retardation. Under advective transport, pollutants travel at the same velocity as the carrier fluid percolating through the porous medium. And if pollutants entered in a groundwater flow system, transport of pollutants is affected mainly by advection process. Therefore if groundwater vector is oriented to a well by pumping or recharging, pollutants will be effectively removed from the contaminated aquifer.

중량물 운반시 잡기유형에 따른 근전도 분석

이훈식,강영택,윤양진,정미라,유국종,서국웅,김정태 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

The purpose of this study was to examine EMG changes of the body according to method the holding during carrying object. The experiments were conducted with utilizing EMG analyses for five male and five female adults as subjects. The results were as followed. 1. The higher muscle action potential of vertical holding was shown than that of right holding when carrying objects in MMH work in proportion to the weight of the object. The came from the subjects using their brachial muscles much to maintain the angles of their wrist joints and elbow joints for keeping their stable postures while walking. 2. The higher muscle action potential of right holding was shown in right and left elector-muscles of their spines(L1-L2, L4-L5) while carrying in all stages of weights except 25kg objects than that of vertical holding. These results were caused from more use of brachial muscles than elector-muscles of spines in carrying weight objects. So vertical holding is more effective in carrying weight objects at a short distance than right holding.

가변적 검사과오를 고려한 계수 1회 선별형샘플링검사에 관한 연구 : 검사과오나 로트불량률이 베타분포를 따를 경우

李相卜,辛周桓,朴永宅 成均館大學校 科學技術硏究所 1989 論文集 Vol.40 No.1

It has been generally assumed in classical sampling inspection plans that the inspection of an item is perfect. However, ergonomic studies show that human errors in inspection tasks are not negligible. Recently, sampling inspection plans under inspection error have been treated extensively in the literature. But, most of them have assumed that inspection errors and lot percent defective are constant. In this study, we removed the rather unrealistic assumption. Assuming that one of the type 1 or type 2 inspection error, lot percent defective follows Beta distribution, W e compute some sampling inspection characteristics such as probability of lot acceptance, average total inspection, and average outgoing quality; and compare them with the results of previous studies.

약년 흡연자에서 Body Plethysmograph를 포함한 폐기능 검사 성적에 관한 연구 : 흡연의 급성 및 만성 효과 Acute and Chronic Effect of smoking

이상도,권오정,이춘택,조상헌,남귀현,한성구,심영수,김건열,한용철 대한내과학회 1990 대한내과학회지 Vol.38 No.3

It is well known that cigarette smoking induces chronic obstructive lung disease. Recently it has been noted that inflammatory changes of the small airways are the earliest lesions of chronic obstructive lung disease. Impairment of pulmonary function in teenage smokers, or in nonsmokers who are exposed chronically to cigarette smoke, is reported frequently, and after stopping cigarette smoking, restoration of pulmonary function is observed. Many studies are currently being carried out regarding pulmonary function tests for early detection of small airway disease. Different from chronic effect of cigarette smoking, increased resistance of central airways is reported as an acute effect of cigarette smoking, while others report increased resistance of small airways as an acute effect of cigarette smoking. There is many controversies about the major site of acute effect of cigarette smoking. Maximal expiratory flow volume curve, airway resistance, compliance(static and dynamic) and closing volume was measured in healthy medical students without present symptoms of pulmonary disease, with the object of comparison of the sensitivity of pulmonary function test items used for detection of small airway disease in young-age smokers, and to study about the acute effect of cigarette smoking. The results are as follows; 1) Mean age of smokers was 22.9±1.2(21~26) years and the mean of their smoking history was 4.2±1.2(3~7) pack-year. Mean age of nonsmokrs was 22.0±1. 0(21~23) years. 2) Compared to nonsmokers, CV/VC was significantly high(p<0.05) and C1.0/C0.0(Cdyn at repiration rate of 60/min/Cst) was significantly low(p<0.05) in smokers, while other pulmonary function test items showed no significant difference between smokers and and nosmokers. 3) Of 21 smokers, 12 persons(57%) showed significant decrease of Cdyn with an increase of respiration rate, while 2 persons(13%) showed abnormal MMF and other 2 showed abnormal CV/VC among 16 smokers who performed the tests and they all showed significant decrease of Cdyn with an increase of respiration rate. 4) Of 21 smokers, 13 persons(62%) had symptoms of cough or sputum, but there was no significant difference of pulmonary function tests between symptomatic and asymtomatic smokers. 5) After smoking, FEV1/FVC, MMF and PEFR were decreased significantly(p<0.05), and SRAW was increased significantly(p<0.005). 6) After smoking, the decrease of C1.0/C0.0 was significantly larger(p<0.05) in nonsmokers compared to smokers and increase of SRAW was somewhat larger in nonsmokers but without statistical significance.