ZnS_(1-x)Te_x 단결정 박막의 격자진동

최용대,남성운,유영문 목원대학교 자연과학연구소 2000 自然科學 硏究論文集 Vol.9 No.1

Hot-wall epitaxy에 의하여 GaAs (100) 기판 위에 성장된 ZnS_1-xTe_x(0<x<1) 단결정 박막의 특성이 Raman 산란을 이용하여 조사되었다. Raman 산란으로부터 측정된 장파장의 ZnTe-like의 longitudinal 광학 포논의 주파수는 성분비 x와 함께 선형으로 변하였다. ZnS_1-xTe_x 단결정 박막의 x의 함수로서 zone-center 광학 포논의 주파수는 two-mode이었고, 이 결과는 MERI 모델의 이론치와 잘 일치하였다. ZnS_1-xTe_x(0<x<1) alloys grown on (100) GaAs substrates by hot-wall epitaxy are investigated using Raman scattering. The frequencies of long wavelength ZnTe-like and ZnTe-like longitudinal optical phonons determined from Raman scattering show linear variation with the composition x. The frequency of the zone-center optical phonons as a function of x of the ZnS_1-xTe_x mixed crystal shows a typical two-mode behavior. which is in good agreement with the theoretical results from a modified random-element isodisplacement model.

가청수중음에 의한 넙치의 행동에 관한 기초적 연구 : 1.육상수조 양식장내의 환경소음

이유철,이창헌,최찬문,박용석,서두옥 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-

A fundamental experiment was carried out to confirm the behaviour of Bastard halibut Paralichthys olivaceus to audible underwater sound in a breeding ground around the coast of Cheju Island. To find characteristics of breeding water tank and experiment water tank. ambient noise, undcrwater noise and feeding sound of fish were measured and analyzied respectively. The results of measurement are as follows: 1. The maximum sound pressure level of ambient noise in breeding water tank was 81dB. average maximum sound level of underwater noise was 81dB at 120Hz. 2. The maximum sound pressure level of ambient noise in experiment water tank was 76dB and underwater noise was 84.2dB at 130Hz. 3. The maximum sound pressure level of feeding sound was 85dB at 120Hz.

쿠싱 증후군을 동반한 부신피질 흑색선종 2예

유소연,김윤화,박용구,이주희,양문호 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.3

세침 흡입 생검으로 진단된 간의 혈관근지방종 1 예

이경아,유은실,민영일,김해련,심기남,정훈용,양석균,홍원선,박의련,이문규 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6

Hepatic angiomyolipoma is a rare benign tumor of the liver composed of blood vessel, smooth muscle cells, fat and myelocomponent. The preoperative diagnosed of the lesion is important because of its therapeutic implications. Radiologic findings are not specific because the composed elements are variable in proportion and distribution. Thus, the findings at computed tomography, ultrasono graphy and magnetic resonance imaging may be only suggestive and its definitive diagnosed requires histologic confirmation. We experienced a case of hepatic angiomyolipoma in patient with chronic hepatitis diagnosed preoperatively by fine-needle aspiraton biopsy under ultrasound guidance. To our knowledge, this is the first case of hepatic angiomyolipoma diagnosed preoperatively in Korea. We report it with review of literatures.

물류시스템 최적화를 위한 설비배치에 관한 연구

박세준,이영해,허선,이문환,유지용 한국경영과학회 1998 한국경영과학회 학술대회논문집 Vol.- No.2

We consider a facility layout problem for optimized material flow system design in the automated production system design. Existing facility layout algorithm have a weak point that arranged facilities have irregular shape or don't preserve their own shape and size. The proposed algorithm give a layout which is minimize total material handling cost and maximize space utility under preserving each facilities own shape and size.

아젭틴 정(염산아젤라스틴 1 mg)에 대한 아젤라 정의 생물학적 동등성

조혜영,윤지훈,서유리,오인준,이성관,문재동,이용복 전남대학교 약품개발연구소 2001 약품개발연구지 Vol.10 No.-

Azelastine, a phthalazinone derivative, is an antiallergic agent which demonstrates histamine H_1-receptor antagonist activity and also inhibits histamine release from mast cells following antigen and non-antigen stimuli. Thus, azelastine may be useful in the management of both asthma and allergic disorders. The purpose of the present study was to evaluate the bioequivalence of two azelastine hydrochloride tablets, Azeptin^TM (Bu Kwang Pharmaceutical Co., Ltd.) and Azela^TM (Kyung Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Eighteen normal male volunteers, 22.44±2.01 years in age and 61.99±6.18㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containing 1㎎ of azelastine hydrochloride per tablet were orally administered, blood was taken at predetermined time intervals and the concentrations of azelastine in serum were determined using HPLC with fluorescence detector. Pharmacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t, C_max and T_max between two tablets were -6.45%, -2.60% and -7.14%, respectively, when calculated against the Azeptin^TM tablet. The powers (1-β) for AUC_t and C_max were 96.65% and 88.47%, respectively. Minimum detectable differences (Δ) at α=0.05 and 1-β=0.8 were less than 20% (e.g., 14.40% and 17.65% for AUC_t and C_max, respectively). The 90% confidence intervals were within ±20% (e.g., -14.87∼1.97 and -12.92∼7.72 for AUC_t and C_max respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Azela^TM tablet is bioequivalent to Azeptin^TM tablet.

낭성 수막종 -1증례 보고-

박재훈,유소연,김윤화,박용구,양문호 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.2

28-Day Oral Toxicity of Cadmium Selenide in Sprague-Dawley Rats

Yong Soon Kim,Moon Yong Song,Jin Sik Kim,Dae Sik Rha,Yong Joon Jeon,Ji Eun Kim,Hyeon Yeol Ryu,Il Je Yu,Kyung Seuk Song 한국독성학회 2009 Toxicological Research Vol.25 No.3

This study was performed to evaluate the toxicity of cadmium selenide for a period of 28 days in Sprague-Dawley rats. Each of 10 healthy male and females rats per group received daily oral administration for 28-day period at dosage levels 30, 300 and 1,000 ㎎/㎏ of body weight. Mortality and clinical signs were checked, and body weight, water intake and food consumption were also recorded weekly. There were no dose-related changes in food consumption or urine volume. All animals survived to the end of study with no clinical signs or differences in body weight gain observed when compared with the control group. At the end of study, all animals including control group, were subjected to necropsy. Blood samples were collected for hematology tests including coagulation time and biochemistry analysis. Blood coagulation time and relative organ weight were unaffected by all received doses. White Blood Cell (WBC) counts significantly increased in the 300 ㎎/㎏ administered male animal group when compared to the control. Monocyte (MO) value were also increased significantly in both 300 and 1,000 ㎎/㎏ male animal group. However, Mean Corpuscular Volume (MCV) were significantly decreased compared with the control in the 1,000 ㎎/㎏ dose groups for male and female animals. Mean Corpuscular Hemoglobin (MCH) decreased significantly for female in the 300 and 1,000 ㎎/㎏ group compared to the control. Blood biochemical values of Inorganic phosphorus (IP) were significantly increased in both the 300 and 1,000 ㎎/㎏ dose groups in male animals when compared to the control. Creatinine (CRE) levels indicated significant increase in kidney function for the female, 30 ㎎/㎏ dose group when compared with control. There was a significant decrease in thymus absolute organ weight in the female, 1,000 ㎎/㎏ dose group when compared with control. Histopathological findings revealed no evidence of injury related to cadmium selenide except for one case of focal hepatic inflammation in the high dose (1,000 ㎎/㎏) group. One case of lung inflammation was also seen in the control group. Basis on these result, the No Observable Adverse Effect Level (NOAEL) of cadmium selenide was determined to be more than 1,000 mg/kg/day for male and female rats under conditions in this study.

28-Day Oral Toxicity of Cadmium Selenide in Sprague-Dawley Rats

Kim, Yong-Soon,Song, Moon-Yong,Kim, Jin-Sik,Rha, Dae-Sik,Jeon, Yong-Joon,Kim, Ji-Eun,Ryu, Hyeon-Yeol,Yu, Il-Je,Song, Kyung-Seuk Korean Society of ToxicologyKorea Environmental Mu 2009 Toxicological Research Vol.26 No.3

This study was performed to evaluate the toxicity of cadmium selenide for a period of 28 days in Sprague-Dawley rats. Each of 10 healthy male and females rats per group received daily oral administration for 28-day period at dosage levels 30, 300 and 1,000 mg/kg of body weight. Mortality and clinical signs were checked, and body weight, water intake and food consumption were also recorded weekly. There were no dose-related changes in food consumption or urine volume. All animals survived to the end of study with no clinical signs or differences in body weight gain observed when compared with the control group. At the end of study, all animals including control group, were subjected to necropsy. Blood samples were collected for hematology tests including coagulation time and biochemistry analysis. Blood coagulation time and relative organ weight were unaffected by all received doses. White Blood Cell (WBC) counts significantly increased in the 300 mg/kg administered male animal group when compared to the control. Monocyte (MO) value were also increased significantly in both 300 and 1,000 mg/kg male animal group. However, Mean Corpuscular Volume (MCV) were significantly decreased compared with the control in the 1,000 mg/kg dose groups for male and female animals. Mean Corpuscular Hemoglobin (MCH) decreased significantly for female in the 300 and 1,000 mg/kg group compared to the control. Blood biochemical values of Inorganic phosphorus (IP) were significantly increased in both the 300 and 1,000 mg/kg dose groups in male animals when compared to the control. Creatinine (CRE) levels indicated significant increase in kidney function for the female, 30 mg/kg dose group when compared with control. There was a significant decrease in thymus absolute organ weight in the female, 1,000 mg/kg dose group when compared with control. Histopathological findings revealed no evidence of injury related to cadmium selenide except for one case of focal hepatic inflammation in the high dose (1,000 mg/kg) group. One case of lung inflammation was also seen in the control group. Basis on these result, the No Observable Adverse Effect Level (NOAEL) of cadmium selenide was determined to be more than 1,000 mg/kg/day for male and female rats under conditions in this study.

Performance Improvement of Near Earth Space Survey (NESS) Wide-Field Telescope (NESS-2) Optics

Yu, Sung-Yeol,Yi, Hyun-Su,Lee, Jae-Hyeob,Yim, Hong-Suh,Choi, Young-Jun,Yang, Ho-Soon,Lee, Yun-Woo,Moon, Hong-Kyu,Byun, Yong-Ik,Han, Won-Yong 한국우주과학회 2010 Journal of Astronomy and Space Sciences Vol.27 No.2