플랜지가 있는 제품에서 부분패드의 영향에 관한 연구

고관영,허주환,문정효,장재석,김동윤,정민섭,김주찬,박기용,이강연,조명우,이권진,조영호,이효걸,김주호,이경희 울산과학대학 2000 연구논문집 Vol.27 No.1

본 논문에서는 기존의 Motion-JPEG 기반 감시시스템에서 낮은 동영상 압축성능 문제를 해결하기 위한 새로운 동영상 압축기법을 제안하였다. 제안된 방법에서는 현재 프레임의 JPEG 데이터 중 변화된 압축 데이터만이 실시간으로 추출하고 저장된다. 제안된 방법에 의해 저장된 데이터는 기존의 JPEG과는 다른 고유의 포맷을 가지기 때문에, 동영상 데이터는 더욱 안전하게 유지될 수 있다. 실험을 통해, 제안된 동영상 압축기법의 압축률이 기존의 Motion-JPEG 기반 감시시스템에 비해 3배정도 높다는 것을 확인할 수 있었다.

중년층의 비처방약품 오남용 실태 연구

고미현,김민주,김유진,김정호,박예진,유리호,이민영,이송연,조윤진,황선주 이화여자대학교 간호과학대학 2014 이화간호학회지 Vol.- No.48

Purpose: The purpose of this study was to grasp the status of abusing Over The Counter Drug (OTC Drug) among the middle-aged. Methods: The participants of this study consisted of 175 middle-aged people in Seoul and Gyeoggi-do. Data were collected using a questionnaire, and the study was conducted from September 10 to October 10, 2013. The data were analyzed by t-test, chi-square test, one-way ANOVA and Turkey. Results : As a result, 97 participants(55.4%) out of 175 participants of this study had taken over the counter drug within the past one year. Their average score of abusive behavior of OTC drug was 6.96±3.01 out of 16. There was significant abusive behavior of OTC drug relative to the difference in family monthly income.(F=3.455, p=0.20) and there was significant difference depending on the information source of the OTC Drug.(F=2.56, p=.044) Conclusions : In conclusion, nurses should educate middle-aged people so that they can use over the counter drug more safely and accurately based on these results. In addition, these results will be useful in further studies regarding middle-aged people’s drug abuse according to the preceding data.

Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells

Jung, M-J,Rho, J-K,Kim, Y-M,Jung, J E,Jin, Y B,Ko, Y-G,Lee, J-S,Lee, S-J,Lee, J C,Park, M-J Macmillan Publishers Limited 2013 Oncogene Vol.32 No.2

The hypothesis of cancer stem cells has been proposed to explain the therapeutic failure in a variety of cancers including lung cancers. Previously, we demonstrated acquisition of epithelial–mesenchymal transition, a feature highly reminiscent of cancer stem-like cells, in gefitinib-resistant A549 cells (A549/GR). Here, we show that A549/GR cells contain a high proportion of CXCR4+ cells that are responsible for having high potential of self-renewal activity in vitro and tumorigenicity in vivo. A549/GR cells exhibited strong sphere-forming activity and high CXCR4 expression and SDF-1α secretion compared with parent cells. Pharmacological inhibition (AMD3100) and/or siRNA transfection targeting CXCR4 significantly suppressed sphere-forming activity in A549 and A549/GR cells, and in various non-small cell lung cancer (NSCLC) cell lines. A549/GR cells showed enhanced Akt, mTOR and STAT3 (Y705) phosphorylation. Pharmacological inhibition of phosphatidyl inositol 3-kinase or transfection with wild-type PTEN suppressed phosphorylation of Akt, mTOR and STAT3 (Y705), sphere formation, and CXCR4 expression in A549/GR cells, whereas mutant PTEN enhanced these events. Inhibition of STAT3 by WP1066 or siSTAT3 significantly suppressed the sphere formation, but not CXCR4 expression, indicating that STAT3 is a downstream effector of CXCR4-mediated signaling. FACS-sorted CXCR4+ A549/GR cells formed many large spheres, had self-renewal capacity, demonstrated radiation resistance in vitro and exhibited stronger tumorigenic potential in vivo than CXCR4− cells. Lentiviral-transduction of CXCR4 enhanced sphere formation and tumorigenicity in H460 and A549 cells, whereas introduction of siCXCR4 suppressed these activities in A549/GR cells. Our data indicate that CXCR4+ NSCLC cells are strong candidates for tumorigenic stem-like cancer cells that maintain stemness through a CXCR4-medated STAT3 pathway and provide a potential therapeutic target for eliminating these malignant cells in NSCLC.

초기성인의 생활습관과 당뇨에 대한 지식

소선이,마지은,고지윤,김은혜,박현화,서유진,서형은,유은미,이하늬,이혜인,정지연,현혜리,이자형,정덕유,강지숙 이화여자대학교 간호과학대학 2009 이화간호학회지 Vol.- No.43

Purposes :The purposes of this study was to investigate the self-managing status according to the life styles and the diabetic knowledge of early adulthood. The subjects in this study were 240people, the early adult aged twenties to thirties living in the metropolitan area. Data were collected by using self-administered questionnaires that measure about the knowledge of diabetes; the dietetic behavior; the knowledge of diet; the exercise behavior; the knowledge of exercise. Descriptive statistics, t-test, ANOVA, and correlation were used for data analysis. Result :1. At the knowledge of diabetes degree based on the general character, the subjects who had experiences of diabetic education have higher degree of the diabetic knowledge. 2. At the knowledge of diabetes degree according to the life style, the subjects who have regular diet are appeared highly. Also the subjects who don't take much food of animal origin have higher degree. 3. At the knowledge of diet based on the life style, the subjects who don't keep three times meals a day are appeared highly. Also the subjects who have regular diet have higher degree. 4. At the knowledge of exercise according to the life style, the subjects who take extra nutritions 3-4 times a week are appeared highly. Although the subjects tend to know about dietary, exercise and health management, it showed that they actually don't perform what they know in their everyday of life. The reason for this could be the lack of perceived seriousness about diabetes mellitus. Thus as nursing professionals, we should provide them proper health education and support. Moreover, advanced research on the empowerment is warranted.

Fabrication and microstructure of hot pressed laminated Y₂O₃/Nd:Y₂O₃/Y₂O₃ transparent ceramics

Gan, L.,Park, Y.J.,Kim, H.,Kim, J.M.,Ko, J.W.,Lee, J.W. Elsevier Science Publishers 2016 Journal of the European Ceramic Society Vol.36 No.3

A transparent three-layered composite Y<SUB>2</SUB>O<SUB>3</SUB>/1at% Nd:Y<SUB>2</SUB>O<SUB>3</SUB>/Y<SUB>2</SUB>O<SUB>3</SUB> ceramic was successfully fabricated by a hot-pressing method. After the hot-pressing step, the laminar structure was maintained very well, and no apparent deformation was found. The sample shows a fine microstructure (the average grain size is ~1μm) without an apparent transition layer between a Nd-doped layer and an undoped layer as a result of the relatively low hot-pressing temperature of only 1600<SUP>o</SUP>C. For a 4-mm-thick polished specimen, the in-line transmittance reaches 59.7% at 400nm and 73.0% at 1100nm.

자유드로잉 제품과 패드를 설치한 드로잉 제품의 특성

고관영,명노훈,하종성,이창수,최창권,최병용,허기영,김광수,김동수,장종훈,장윤철,김세환,오정민,하민정,박향자 울산과학대학 2000 연구논문집 Vol.27 No.1

본 연구는 자체 제작한 전체 패드가 부착된 드로잉 금형을 이용하여 SUS, 연강, AI, 6:4황동 판재를 드로잉 가공하여 생산된 제품의 특성을 자유드로잉 하여 얻은 제품의 특성과 비교 분석하였다. SUS 판재의 경우 제품에 발생하는 현상은 벽 주름, 구변주름, 수직 파단, 드로잉상처, 이어링이 발생하였으며 길이변화는 펀치어깨부분에서 가장 많이 늘어남을 볼 수 있었고 벽 주름 부분에 있어서 접혀진 부분은 상대적으로 적게 늘어남을 볼 수 있었다. 연강 판재는 SUS 판재에서 보여준 현상을 나타내었으나 SUS 판재에 비해 수직 파단은 적게 일어난 반면 이어링이 더 크게 일어났다. AI 판재의 경우 수직 파단은 일어나지 않았으나 플랜지 주름과 밑면터짐이 발생하였다. 6:4황동의 경우는 전체패드의 AI 판재 드로잉에서와 같이 밑면터짐과 플랜지 주름의 발생이 일어났다.

드로잉 금형에 있어서 비드의 영향

고관영,최원정,조재희,명노훈,이창수,최병용,허주환,최창권,장종훈,장윤철,박기용 울산과학대학 2001 연구논문집 Vol.28 No.1

본 연구는 자체 제작한 다이 측 비드가 설치 된 드로잉 금형을 이용하여 SUS 304, 6:4 황동 판재를 드로잉 가공하여 생산된 제품의 치수변형 특성을, 비드를 설치하지 않은 자유 드로잉 하여 얻은 제품과 비교하였다. SUS 304 판재의 경우, 비드를 설치하여 드로잉 한 경우는 늘어난 길이의 변화가 연속적으로 증가하고 있고, 비드를 설치하지 않은 경우는 마지막 부분에서 다시 회복상태를 보였다. 그 원인은 드로잉 비드로 인하여 적정량의 유입으로 일정 비율로 늘어난 것이라고 볼 수 있다. 6:4 황동 판재의 경우는 비드를 설치한 경우의 치수 변형값이 비드를 설치하지 않은 경우보다 안정함을 보여주었다. In this research, properties of SUS 304 and 6:4 brass products produced by die bead-drawing mold were compared with those of products drawed without bead. In the case of bead-SUS-plate, variation of incremental length progressively increases, while, in the case of no bead-SUS-plate, recovery appeared at the final-part. The reason of this difference is considered as proper insert of metal-plate on the basis of bead. Bead-6:4 brass-plate showed more stable data than no-bead die case although it did not show recovery in final-part.

Immunogenic proteins of Brucella abortus to minimize cross reactions in brucellosis diagnosis

Ko, K.Y.,Kim, J.W.,Her, M.,Kang, S.I.,Jung, S.C.,Cho, D.H.,Kim, J.Y. Elsevier Scientific Pub. Co 2012 Veterinary microbiology Vol.156 No.3

To overcome the limitations of serological diagnosis, including false positive reactions caused by other pathogens, specific antigens for diagnosis of brucellosis other than LPS have been required. The present study was conducted to separate and identify immuno-dominant insoluble proteins of Brucella abortus against the antisera of cattle infected with B. abortus, or/and Yersinia enterocolitica, or the sera of non-infected cattle. After separating insoluble proteins of B. abortus by two dimensional electrophoresis (2-DE), their immuno-reactivity was determined by western blotting. A portion of the immunogenic spots against the positive antisera of B. abortus that have the potential for use as specific antigens were identified by MS/MS analysis. Overall, 18 immunogenic insoluble proteins of B. abortus 1119-3 showed immuno-reactivity against only the positive antisera of B. abortus, but failed to have immunogenicity toward both the positive sera of Y. enterocolitica and the negative sera of B. abortus. Identification of these proteins revealed the following: F0F1 ATP synthase subunit β, solute-binding family 5 protein, 28kDa OMP, Leu/Ile/Val-binding family protein, Histidinol dehyddrogenase, Hypothetical protein, Twin-arginine translocation pathway signal sequence domain-containing protein, Dihydroorotase, Serine protease family protein, β-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA, Short-chain dehydrogenase-/reductase carbonic anhydrase, Orinithine carbamoyltransferase, Leucyl aminopeptidase, Cold shock DNA-binding domain-containing protein, Cu/Zn superoxide dismutase, and Methionine aminopeptidase. The 18 immunogenic proteins separated in the present study can be considered candidate antigens to minimize cross reaction in the diagnosis of brucellosis and useful sources for Brucella vaccine development.

대학생의 스마트폰 중독 정도, 안구건조증, 경부 통증 및 수면의 질에 관한 연구

고은재,김나연,김도연,김은혜,김지연,박영신,심현수,윤지현,이소미,이해수,박효정 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

Purpose: The purpose of this study was to identify correlation among the degree of smartphone addiction, dry eye syndromes, neck pain and sleep quality. Method: A total of 172 students were recruited for the data collection. Data were analyzed using frequency, percentage, average, standard deviation, t-test, ANOVA, Scheffe test and Pearson's correlation using the SPSS program. Results: The degree of smartphone addiction, dry eye syndromes, neck pain and sleep quality showed positive correlation. As the level of smartphone addiction is higher, dry eye syndromes, neck pain and sleep quality become worsen. Conclusion: Based on the results of this study, it shows that the quality of sleep had a significant correlation with smartphone addiction. Therefore, it is necessary to consider the nursing intervention to increase the quality of sleep, neck pain and dry eye syndromes in further study.

몇가지 원료사료의 영양소 이용성에 관한 연구 (2) 젖소 소화기관내에서의 건물 및 조단밸질의 소실률과 이용성

하종규(J . K . Ha),이성실(S . S . Lee),곽병오(B . O . Kwak),문태현(T . H . Moon),고영곤(Y . K . Ko),문양수(Y . S . Moon),이상철(S . C . Lee) 한국영양사료학회 1993 韓國營養飼料學會誌 Vol.17 No.6