조혈모세포이식 환자에서 발생한 Cytomegalovirus 질환의 특징 : 일개 대학변원에서 최근 10년간의 경험

최수미,이동건,박선희,김시현,김유진,민창기,김희제,이석,최정현,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Studies on cytomegalovirus (CMV) diseases in Korean hematopoietic stem cell transplant (HSCT) recipients are lacking and do not reflect the recent trends of advances and changes. Therefore, we tried to analyze the clinical features of CMV diseases in HSCT recipients over the past 10 years at a tertiary university hospital in Korea. Methods : Retrospective review of medical records was done for all adult HSCT patients who received transplant at the Catholic HSCT Center from January 1998 to January 2008. Results : Forty-four cases (2.2%) of CMV diseases were identified. CMV pneumonia was diagnosed in 17 patients, retinitis in 16 patients, enterocolitis in 7 patients, esophagitis 1 patient, gastritis in 1 patient, duodenitis in 1 patient, and hepatitis in 1 patient. The median onset of symptom was 90 days after transplantation. Late CMV diseases accounted for 47.7%. CMV related death varied from 0 to 58.8% according to the involved organ. CMV retinitis was diagnosed relatively later in the course of transplantation mostly in patients who had chronic graft versus host disease (GVHD). On the contrary, CMV enterocolitis mainly occurred in patients who suffered from acute GVHD. The overall concurrent CMV reactivation was documented to be 63.6%: the concurrent CMV reactivation was observed only in 37.5% of patients with retinitis. Conclusions : We observed some differences in the pattern of CMV disease manifestation according to the involved organ and reconfirmed the fact that CMV pneumonia is the most common and fatal disease in HSCT recipients. Additionally, CMV retinitis was not uncommon in HSCT recipients. Since specific marker does not exist in predicting retinitis, regular ocular examination should be done thoroughly, especially in patients with chronic GVHD.

성인 지역사회 폐렴의 원인 미생물에 대한 전향적 다기관 연구 : Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

김민자,정희진,손장욱,심희선,박대원,박승철,우준희,강재명,김유겸,신완식,김양리,이환종,김지희 대한감염학회 2001 감염 Vol.33 No.1

Background : Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical as number of newer pathogens have been recognized in recent years. In the 3-year period prospective study we investigated adult patients with community-acquired pneumonia for Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi as potential etiologic agents. Methods : A prospective multicenter study was performed from May 1997 to April 2000. A total of 431 patients with community-acquired pneumonia under the inclusion criteria were examined for specific microbial diagnosis; sputum culture and PCR, and serologic teats including indirect immunofluorescence antibody (IFA) test for Legionella, and hemagglutination tests for Leptosoira, Hantaan virus and O. tsutsugamushi. Etiologic diagnosis was determined on the basis of the review of case record forms and specific laboratory diagnostic criteria. Results : During the study period a total of 385 sputum and 283 serum samples were examined. Legionella pneumonia was diagnosed in 2.3% (10/431) of the cases examined : 1.4% cases with PCR-positive (5/367) and 2.1% with positive IFA test (6/283). Leptospirosis and scrub typhus were diagnosed in 0.4% (1/252) and 2.0% (5/252), respectively. All 5 cases with scrub typhus occurred in late fall, and rash or eschar was not found. None of cases was Hantaan virus infection. Conclusion : The results suggest that Legionella, Leptospira, and O. tsutsugamushi should be considered in the etiologic diagnosis and empirical antibiotic therapy of community-acquired pneumonia. (Korean J Infect Dis 32:24∼31, 2001)

4주간의 쥐뒷다리 고정이 Soleus근섬유 조성에 미친 영향

이선장,김완조,김문희 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

The purpose of this study was to examine the effect of immobilization on muscle fiber composition, mass, area and capillarization after 4 - wk of hindlimb suspension. Significant reductions in soleus mass, area and capillary density were occured after 4 wks of hindlimb suspension, Wheres type IIa fiber percentage was significantly increased in the experimental group. The results suggest that hindlimb unweighting induced soleus muscle atropy and these results also demonstrate that muscle fiber atropy not necessarily being associated with a loss in capillary supply.

아미노산 투여가 중장거리 운동선수의 최대 및 최대하운동시 젖산생성에 미치는 영향

이정수,윤탁영,김문희,이선장,김완조 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

The Purpose of the Study was to determine whether the glutamate ingestion prior to exercise would reduce the lactat formation and its clearance in exercising mscle tisue during Submaximal and maximal execise. Six elite distance rummers particapated in this study. The Subjects had a half dose of glutamale(15.6mg .Kg?? ??) at 45min and ingested rest dose at prior to exerise. The test Performed twice. One was Performed in the track and the other was in the Lab. Blood Smples were obtained from catheter which was placed in the antecubital vein (Lab test) and finger tip Samples (Feld test) Unaltered blood lactate was observed in both trials, but, tended to less lactate concentration with glutamate ingestion than that of without glutamate ingestion. The recovery rate of blood lactate was markely rapid with glutamate ingestion in the field test. Unchanged in heart rate was founded in both trials. It many Suggest that, the additional supplement st of glutamate can improve execise performance limiting lactate formation or induce its rapid clearance from the muscle fissue.

이온화에너지 처리 아이스크림 및 우유의 단회투여 독성시험

이희준,최현종,한선경,구본철,신명수,함준상,조철훈,이완규 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

비정질 금속 리본 Co66Fe4NiB14Si15 거대자기임피턴스 효과

이희복,조완식 公州大學校 基礎科學硏究所 1996 自然科學硏究 Vol.5 No.-

비정질 금속 ?? 거대자기임피턴스 효과를 측정하였다. 자기 임피턴스 효과는 강자성체 시료의 임피턴스가 시료에 걸어준 자기장에 따라서 달라지는 현상이다. MlR (Magnetoimpedance Ratios)는 ?? 정의되며 ? 시료방향으로 자기장을 가하여 임피턴스가 포화될 때의 자기장의 세기이다. 본 시료의 MIR 값은 적절한 자장중 열처리 후에 250 %이상 증가하였다. The giant magnetoimpedance (GMI) effect in amorphous ribbon ?? has been obtained. Magnetoimpedance (MI) effect is a high-frequency phenomenon, which describes the changes of impedance in any ferromagnetic sample, when a magnetic field is applied on it. MlR(Magnetoimpedance Ratios) is defined as ?? where ?? is the saturating field along the long side of the sample. The MIR of the sample has been reached as much as 250% after proper thermal treatments in a magnetic field.

교육대학교 대학원 예체능 교육과정에관한 연구

이완섭,김정희,유원 춘천교육대학교 예체능교육연구소 1987 예체능교육연구 Vol.2 No.-

팔공산 화강암지역 지하수에 대한 지구환경화학적 연구

李基完,朴喜烈 東新大學校 1997 論文集 Vol.9 No.-

Recently, the importance of groundwater is higher as the use of groundwater for drinking, agriculture and industry sisnificantly increases. However, groundwater has been contaminated by industrial waste, domestic sewage, landfill leachate and seawater intrusion. Therefore, it is necessary to understand the chemical characteristics and water-rock interaction of groundwater for the preservation of groundwater resources. The purpose of this study is to find out the magnitude of groundwater contamination, and its water-rock interaction characteristics in granitic regions. The Cretaceous Palgongsan granitic regions are selected as the study area. The results are as follows : Groundwater is contamimated by NO_3^- in a Part (CP-3, CP-4, CP-5) of study region. K^+/Na^+ in groundwater of study legion is equivalent to 1/10 for K_2O/Na_2O of rock. Groundwater's evolution is being progressed to noncarbonate hardness tupe of Ca^2+ -HCO_3^-, continuously noncabonate alkali type of Ca^2+, Cl^-, SO_4^2-. Saturation index of aluminosilicate minerals for groundwater is dominated kaolinite. This indicates the initial evolution process of groundwater.

大學生의 100m 疾走能力 分析硏究

李完熙 春川敎育大學 1986 論文集 Vol.26 No.-

高校生의 100m 疾走能力 分析 硏究

李完熙 春川敎育大學 1985 論文集 Vol.25 No.-

I studies for the 100r3 running ability of the students in the High School. This study is purposed on the Surveying of the factors to be needed for the inprovement on the running record and on the materials which can be used in the fields of education, Two hundred and forty three students(boys and girls in the all grades of C. boys highschool and C. girls high school in chun cheon.) served as assubjects. They were tested and analyged during septemter, 17-22, 1984. The results are as follows ; As shown in the above 1. The boy-students were faster than the girls in average running records in each section without relating to their ages. 2. The boy-students speed average also faster than the girls in each section. 3. The total numbers of the step3 for the boys were less frequency than for girls in each section without relating to their ages. 4. The average distance per step of the boys lager than of the girls in each section without relating to their ages. 5. The speed maintenance rate of the girls, except the case of 18 years, was higher than of the boys. 6. The speed deceleration rate of the girls, except the case of 18 year3, was lower than of the boys. 7. The speed acceleration rate of the boys higher than of the girls without relating to their ages.