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Hae Suk Cheong,Ki-Tae Kwon,Ji-Young Rhee,Seong Yeol Ryu,Dong Sik Jung,Sang Taek Heo,Sang Yop Shin,Doo Ryun Chung,Kyong Ran Peck,Jae-Hoon Song 대한기생충학열대의학회 2009 The Korean Journal of Parasitology Vol.47 No.3
The incidence of imported malaria has been increasing in Korea. We reviewed data retrospectively to evaluate the epidemiology, clinical features, and outcomes of imported malaria from 1995 to 2007 in a university hospital. All patients diagnosed with imported malaria were included. Imported malaria was defined as a positive smear for malaria that was acquired in a foreign country. A total of 49 patients (mean age, 35.7 year; M : F = 38 : 11) were enrolled. The predominant malarial species was Plasmodium falciparum (73.5%), and the most frequent area of acquisition was Africa (55.1%), followed by Southeast Asia (22.4%) and South Asia (18.4%). Fourteen-patients (30.6%) suffered from severe malaria caused by P. falciparum and 1 patient (2.0%) died of multiorgan failure. Most of the patients were treated with mefloquine (79.2%) or quinine (10.2%); other antimalarial agents had to be given in 13.2% treated with mefloquine and 44.4% with quinine due to adverse drug events (ADEs). P. falciparum was the most common cause of imported malaria, with the majority of cases acquired from Africa, and a significant number of patients had severe malaria. Alternative antimalarial agents with lower rates of ADEs might be considered for effective treatment instead of mefloquine and quinine.
Hye-Jin Yoon,Kyung Hwan Kim,Yeon-Hee Lee,Eun-Jung Suh,Taek-Ryun Kwon 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07
Research on salinity stress has strongly increased over the last decade, as salinity stress is a main key factor limiting the global crop production in many regions of the world. In recent years, it is possible to obtain a large amount of genotypic data in a short time due to a reduction in genotyping costs. This wave of genomic information has effected the development of new strategies for the integration of molecular information in breeding programs. However, phenotyping is still a manual activity, and different from each species, environment, and trait. It often generates high labor costs, and can be sensitive to environmental changes, and sometimes includes the individual biased assessments from different people. There is a strong demand for phenotypic data of high quality. The current objective of phenomics is phenotyping a large number of individuals for many traits in a nondestructive manner and with good accuracy. Here we described the image-based technology as applied to alleviate the bottleneck for the development of high-throughput phenotyping platforms. Several trials to measure stress responses of rice plantlets based on image data under the salinity condition are underway to develop automation for the next-level of phenotyping.
김경욱,김종우,황의완,김현택,박순권,이정륜 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.2
Background : The aim of this study was to evaluate the effect of Punsimgieumgamibang on insomnia and anxiety. which is widely used in mental diseases. Method : We admitted Punsimgieumgamibang into rats which illumination of the sleeping periodhas been reversed, and measured its activity rate during the sleeping period. Also we studied the effect of Punsimgieumgamibang on anxiety using analyses of Punsimgieumgamibang on anxiety using analyses of behavior of rats submitted to the elevated plus-maze test. Result : 1) The sleeping ratio of the Pusimgieumgamibang group was higher than the control group on the whole, and the difference of the groups in the third time block was significant statistically. 2) We could not find any statistical information in all of the 4 anxiety related behavior of the elevated plus-maze experiment. and there was a tendency to a higher measurement in the Punsimgieumgamibang group animals in the total arms visitation in the elevated plus-maze, open arms visitation, and the amount of time of stay in arms. Conclusion : It is suggested that Pusimgieumgamibang has effects on insomnia. 1
제2형 당뇨병환자들이 사용하는 그릇 용량과 식사 섭취량과의 관계
안희정 ( Hee Jung Ahn ),구보경 ( Bo Kyung Koo ),정지연 ( Ji Yeon Jung ),권휘련 ( Hwi Ryun Kwon ),정미연 ( Mi Yeon Chung ),구윤희 ( Yun Hyi Ku ),김진택 ( Jin Taek Kim ),한경아 ( Kyung Ah Han ),민경완 ( Kyung Wan Min ) 대한당뇨병학회 2009 Diabetes and Metabolism Journal Vol.33 No.4
연구배경: 식품의 1회 섭취 분량이나 담는 그릇의 용량은 섭취량에 영향을 미친다. 이에 본 연구는 제2형 당뇨병환자들에서 밥 중심의 식사하는 횟수와 식사에 사용하는 그릇의 용량을 조사하였고, 그릇 용량과 섭취량과의 관계를 조사하고자 하였다. 방법: 제2형 당뇨병환자 203명을 대상으로 식사 형태와 장소는 7일 기록지로 조사하였고, 사용 중인 밥그릇, 국그릇, 반찬 그릇의 용량은 메스실린더로 측정하였다. 식사에너지와 영양소 섭취량은 3일 식사 기록지를 통해 조사하였다. 결과: 연구 대상자(남자: 76명, 여자: 127명)들의 평균 나이는 53.9±9.1세, 비만도는 25.6±4.2 kg/m2였다. 하루 세 끼니를 모두 섭취하는 환자 중 2끼 이상 밥으로 섭취하는 경우는 96.4%였다. 사용하는 밥그릇 용량의 중앙값은 350 cc였으며 국그릇은 530 cc, 반찬 그릇은 260 cc였다. 밥그릇, 국그릇, 반찬 그릇 용량과 비만도는 유의한 상관관계가 없었고, 밥그릇과 국그릇의 용량은 남자에서 더 컸다(P<0.001). 남자에서 밥그릇 용량은 밥의 에너지 섭취량(kcal/kg/day)과 상관관계가 있었으나(P=0.018), 식사 에너지 섭취량(kcal/kg/day)과는 상관관계가 없었다. 결론: 제2형 남자 당뇨병환자에서 밥그릇 용량은 밥의 에너지 섭취량과 상관관계가 있었으나 식사 에너지 섭취량과는 상관관계를 보이지 못하였다. 이러한 결과로 미루어 그릇을 활용한 식사계획법이 교육에 활용되기 위해서는 식기용량과 다른 임상적 지표들과의 관계, 성별을 고려한 섭취량에 영향을 미치는 요인들과의 관계를 밝히는 추후 연구가 필요할 것으로 보인다. Background: The results of previous studies suggest that portion size is a major factor dictating dietary energy intake. We investigated the relationship between frequencies of rice meals, bowl volumes, and dietary energy intake in a sample of patients with type 2 diabetes. Methods: A total of 203 type 2 diabetes patients were enrolled in the study. A one-week food diary was collected from each patient and used to assess the types of meal consumed as well as the context of consumption. The volumes of the eating vessels (rice, soup and side dish bowls) used by each patient were obtained by comparisons to measuring cylinders, and dietary energy and macronutrient intake were estimated for each patient by consulting three-day dietary records. Results: The mean age of the 203 subjects (male: 76, female: 127) was 53.9±9.1 years and the average body mass index (BMI) was 25.6±4.2 kg/m2. Among the subjects who ate three times per day, 96.4% consumed rice more than twice out of three meals. The median volume of rice bowls used by patients was 350 cc, of soup bowls was 530 cc and of side dish bowls was 260 cc. Portion size, as estimated by rice bowl volume, was not associated with BMI. Male subjects tended to eat out of larger rice and soup bowls (P<0.001). Portion size was correlated with energy intake from rice (P=0.021), but not with total energy intake (kcal/kg/day), especially in male subjects. Conclusion: Portion size of rice bowl was correlated with energy intake from rice, but not with total energy intake in male subjects with type 2 diabetes. To design effective meal planning methods for patients with type 2 diabetes, further prospective studies are warranted to investigate causative relationships between portion size andmetabolic conditions as well as variation by gender. (Korean Diabetes J 33:335-343, 2009)
Cho, Yoo-Hyun,Lee, Sok-Young,Kim, Seong-Min,Yu, Jae-Woong,Lee, Jung-Ro,Hong, Ha-Cheol,Kim, Jung-Bong,Ma, Kyung-Ho,Kwon, Taek-Ryun,Kang, Hee-Kyoung,Lee, Gi-An,Gwag, Jae-Gyun,Kim, Tae-San,Park, Yong-Jin The Korean Society of Crop Science 2008 Journal of crop science and biotechnology Vol.11 No.3
To assess the potential as biofortified rice varieties, new endosperm and grain mutant lines were selected from $M_4$ generation seeds of the rice cultivar Shindongjin, which were either $\gamma$-irradiated or treated with N-methyl-N-nitrosourea(MNU) and lipid, sugar, and tocopherol content were analyzed. Amylose content in non-waxy mutants ranged from 8.8% in SM-4, a dull-type mutant, to 29.5% in SM-51, compared to 18.9% in the parental variety, Shindongjin. SM-23, a floury-type mutant, contained 0.09 ${\mu}g/g$ $\alpha$-tocopherol(40.9% of total tocopherol), was three times higher than in the parental variety. SM-32, a giant embryo-type mutant, had a 2.2-fold higher total tocopherol content, 2.1-fold higher $\alpha$-tocopherol, and 5.5-fold higher $\delta$-tocopherol content(47.3% of total tocopherol) than the parental variety(0.13 ${\mu}g/g$). Total free sugar content was elevated in all selected mutants and 1.2-8.6 times higher than in the parental variety(11.38 ${\mu}g/g$). These increased sugar levels were due to increase in sucrose concentration. SM-23(floury-type mutant) and SM-51(high amylose-type mutant) had 4.6 and 7.0 times more sugar, respectively, than the parental variety(11.38 ${\mu}g/g$). With relatively high concentrations, most mutants showed elevated fatty acid content in the SM 32(giant embryo-type) and SM-51(high amylose-type) mutants, at 124.56 and 89.59 mg/g, respectively. All selected mutants displayed valuable characteristics for the development of new varieties in rice-breeding programs.
조유현,Sok-Young Lee,Seong-Min Kim,Jae-Woong Yu,Jung-Ro Lee,Ha-Cheol Hong,Jung-Bong Kim,Kyung-Ho Ma,Taek-Ryun Kwon,Hee-Kyoung Kang,이지안,Jae-Gyun Gwag,Tae-San Kim,Yong-Jin Park 한국작물학회 2008 Journal of crop science and biotechnology Vol.11 No.3
To assess the potential as biofortified rice varieties, new endosperm and grain mutant lines were selected from M4 generation seeds of the rice cultivar Shindongjin, which were either γ-irradiated or treated with N-methyl-N-nitrosourea (MNU) and lipid, sugar, and tocopherol content were analyzed. Amylose content in non-waxy mutants ranged from 8.8% in SM-4, a dull-type mutant, to 29.5% in SM-51, compared to 18.9% in the parental variety, Shindongjin. SM-23, a floury-type mutant, contained 0.09 μg/g α-tocopherol (40.9% of total tocopherol), was three times higher than in the parental variety. SM-32, a giant embryo-type mutant, had a 2.2-fold higher total tocopherol content, 2.1-fold higher α-tocopherol, and 5.5-fold higher δ-tocopherol content (47.3% of total tocopherol) than the parental variety (0.13 μg/g). Total free sugar content was elevated in all selected mutants and 1.2-8.6 times higher than in the parental variety (11.38 μg/g). These increased sugar levels were due to increase in sucrose concentration. SM-23 (floury-type mutant) and SM-51 (high amylose-type mutant) had 4.6 and 7.0 times more sugar, respectively, than the parental variety (11.38 μg/g). With relatively high concentrations, most mutants showed elevated fatty acid content in the SM 32 (giant embryo-type) and SM-51 (high amylose-type) mutants, at 124.56 and 89.59 mg/g, respectively. All selected mutants displayed valuable characteristics for the development of new varieties in rice-breeding programs. To assess the potential as biofortified rice varieties, new endosperm and grain mutant lines were selected from M4 generation seeds of the rice cultivar Shindongjin, which were either γ-irradiated or treated with N-methyl-N-nitrosourea (MNU) and lipid, sugar, and tocopherol content were analyzed. Amylose content in non-waxy mutants ranged from 8.8% in SM-4, a dull-type mutant, to 29.5% in SM-51, compared to 18.9% in the parental variety, Shindongjin. SM-23, a floury-type mutant, contained 0.09 μg/g α-tocopherol (40.9% of total tocopherol), was three times higher than in the parental variety. SM-32, a giant embryo-type mutant, had a 2.2-fold higher total tocopherol content, 2.1-fold higher α-tocopherol, and 5.5-fold higher δ-tocopherol content (47.3% of total tocopherol) than the parental variety (0.13 μg/g). Total free sugar content was elevated in all selected mutants and 1.2-8.6 times higher than in the parental variety (11.38 μg/g). These increased sugar levels were due to increase in sucrose concentration. SM-23 (floury-type mutant) and SM-51 (high amylose-type mutant) had 4.6 and 7.0 times more sugar, respectively, than the parental variety (11.38 μg/g). With relatively high concentrations, most mutants showed elevated fatty acid content in the SM 32 (giant embryo-type) and SM-51 (high amylose-type) mutants, at 124.56 and 89.59 mg/g, respectively. All selected mutants displayed valuable characteristics for the development of new varieties in rice-breeding programs.