제조에 對한 文獻的 考察

안태규,최병렬,송기철,이용연,유화승,서상훈,최우진,조정효,이연월,손창규,조종관 대전대학교 한방병원 2001 惠和醫學 Vol.10 No.1

In the literatual study on Holotrichia, the results were obtained as follows ; 1. Holotrichia is larva of Holotrichia diomphalia Bates etc. powder or liquor of Holotrichia is used medically. 2. Appearance of Holotrichia is shape of kidney, yellowish color. 3. The oriental characters of Holotrichia is warm, toxicant, salty. 4. The significant efficancy of Holotrichia is breaking the stagnant blood. 5. Holotrichia can be applied to the diseases related to thrombosis, and recover the demage of liver. 6. Holotrichia avails Liver diseases such as Hepatitis, Liver cirrhosis, Hepatosplenomegaly, Hepatoma etc.

분리된 서스펜션 극을 가지는 베어링리스 SRM의 직접 공극 제어기법

박태흡,이동희,안진우 경성대학교 공학기술연구소 2010 공학기술연구지 Vol.16 No.-

This paper presents direct radial force control scheme of bearingless SRM with separated torque and suspending winding poles. The proposed motor has separated stator poles for radial force winding and phase winding. And the radial force stator pole is placed opposite and perpendicular position for continuous radial force generation. In order to keep the rotor to the center of the motor, radial forces in x and y direction are controlled by the radial force winding current. The proposed radial force control scheme is independent to phase torque winding current. A simple Pill controller and look-up table are used to maintain constant rotor air-gap.

비호지킨 림프종환자에서 proMACE-cytaBOM 복합항암화학요법의 유효성에 대한 제 2상 임상시험

김성우,안명주,박석규,이영렬,정태준,최일영,김인순 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1

Aggressive non-Hodgkin's lymphoma by REAL classification is a heterogenous group of disease. With recent advances in combination chemotherapy, the long-term survival is improved to 40-65%. We investigated twenty-one aggressive non-Hodgkin's lymphoma patients treated with pro-MACE-cytaBOM (prednisone, adriamycin, cyclophosphamide, etoposide, cytosine arabinoside, bleomycin, vincristine and methotrexated) to determine the efficacy and toxicites. There were seven patients older than 60 years. Histologic types by REAL classification were as follows : diffuse large B cell (12/21), peripheral T cell (6/21), anaplastic large cell (2/21) and angiocentric T cell (1/21). Most of patients were classified in Stage Ⅱ-Ⅳ (20/21). According to IPI (international prognostic index) score, seven patients were included in low risk, five were low-intermediate risk, three were high-intermediated risk and six were high risk group. seventeen complete responses (85%) and two partial responses (10%) were achieved. The overall response rate was 95%. The mena disease free survival was 30 months, the mean overall survival was 29 months (range:21-36), and the median overall survival was not reached. WHO grade Ⅲ/Ⅳ neutropenia or thrombocytopenia was observed in 16.7% and 2.8%, respectively. There was no treatment-related death. These results suggest that proMACE-cytaBOM combination chemotherapy is very effective and has low toxicity in the treatment of aggressive non-Hodgkin's lymphoma even treated in elderly patients.

釜山市 主要 道路邊의 振動 및 騷音에 관한 調査硏究

全泰玉,安贊祐 동아대학교 환경문제연구소 1987 硏究報告 Vol.10 No.1

This study is concerned with the measurement and analysis on the actual conditions of vibration and noise at the main roadside in pusan. It's results excess on level of environmental vibration and noise requisite to protect public health and welfare with an adequate margin of safety. Vibration and noise pollution affect the health of human beings and its actual condition is more and more serious by high speed of various vehicles and development of industry. It will contribute to the vibration and noise control.

능동 클램프 ZVS 플라이백 컨버터의 역률개선에 관한 연구

최태영,류동균,이우석,안정준,원충연,김수석 성균관대학교 2002 학술회의지원논문목록집 Vol.2002 No.-

본 논문에서는 single-stage, two-stage 두가지 역률보상(PFC)기법을 기존의 능동 클램프 플라이백 컨버터에 적용하여 역률 개선을 하였다. 삽입된 플라이백 컨버터의 능동클램프회로가 주스위치와 보조스위치의 영전압스위칭(ZVS)을 구현하며, 스위칭 손실을 줄임으로써 고효율을 얻을 수 있고, 높은 주파수에서의 스위칭이 가능하다. 하지만 일반적으로 사용되는 다이오드정류기, 평활용커패시터에 의한 낮은 역률의 문제점이 남아있다. 본 논문에서는 300W급 능동 클램프ZVS플라이백 컨버터를 설계하여 single-stage, two-stage방식을 적용, 입력역률개선을 시뮬레이션과 실험에 의해 입증하고자 한다. This paper analyzed PFC of active clamp ZVS flyback converter by adding two method PFC (Power Factor Correction) circuit - two-stage and single-stage. The addition of active clamp circuit also provide a mechanism for achieving ZVS of both the primary and auxiliary switches. ZVS also limits the turn off di/dt of the output rectifier, reducing rectifier switching loss and switching noise, due to diode reverse recovery. As a results, the proposed converters have characteristics of the reduced switching noise and high efficiency in comparison to conventional flyback converter. The simulation and experimental results show that the proposed converters improve the input PF of 300W ZVS flyback converter by adding single-stage, two-stage PFC circuit.

소양호 유역과 가두리로부터의 인부하량 및 인수지 : Phosphorus Budget

허우명,김범철,안태석,이기종 江原大學校 附設 環境硏究所 1993 環境硏究 Vol.10 No.-

Phosphorus loading into Lake Soyang was estimated by determining phosphorus input via runoff of drainage basin and the phosphorus discharge from floating-net fishfarms within the lake. The loading from drainage basin was determined by measur-ing total phosphorus concentration in the main inflowing stream, Syang River, from July 1990 to May 1992. Because the total phosphorus concentration and the flow rate of Soyang River was high in flood period, most of phosphorus loading was concentrated in rainy season. Phosphorus discharge of fishfarms was estimated from the amount of fishfeed applied annually and the unit rate of phosphorus excretion per feed weight. The loading from the watershed and fishfarms were calculated to be 104 and 48 tP/yr, respectively. Both combined, the phosphorus loading of Lake Soyang far exceeded the critical loading for eutrophication. The amount of phosphorus was 0.59.

BOX-Wilson 실험계획법에 의한 인산알루미늄의 최적합성조건에 관한 연구

신화우,강태욱,안세민 원광대학교 식품약품안전성연구소 1992 食品藥品安全性硏究 Vol.5 No.-

Aluminum phosphate is used as an antacid in pharmacy as the gel or dried gel, must meet specified neutralization rate and acid consuming capacity criteria. This nonadsorbable antacid has been used in place of aluminum hydroxide gel where loss of phosphate may be a problem to the patient. Since aluminum phosphate gel is regenerated in the intestine, endogenous phosphate is spared. The acid-consuming ability of aluminum phosphate is based on the release of phosphate anion : AlPO_4 ?? Al^3+ + PO^3-, PO^3-_4 + H_3O^+ ?? HPO^2-_4 + H_2O, HPO^2-_4 + H_3O^- ?? H_2PO_4 + H_2O. Aluminum phosphate gel was synthesized by reacting aluminum chloride as a soluble aluminum salt to sodium phosphate in this study ; AlCl_3 + NaPO_4 → AlPO_4↓ + 3NaCl. The optimum synthesis conditions based on the yield of product were investigated by applying Box-Wilson experimental design. It was found that optimal synthesis conditions were as follows ; Reaction temperature;90∼98℃, Concentration of two reactants;15.3∼15.5%, Concentration ratio of two reactants, [Na_3PO_4]/[AlCl_3];1.48∼1.49, reaction time;10minutes, drying temperature of product;60∼70℃.

Factor analysis of Water Quality and Ecosystem in Jinhae Bay

홍순우,하영칠,안태석 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-

진해만의 6개 정점의 표·지층에서 1976년 7월부터 1982년 12월까지 물리화학적, 생물학적인 환경요소를 65회에 걸쳐 조사하였다. 이들 자료를 통계학적인 분석을 통하여 진해만의 수질및 생태계에 영향을 미치는 요인을 분석하였다. 그 결과 행암만 내부에 위치한 정점 6 을 제외한 전 해역에서 식물성 플랑크톤의 이상증식이 주요한 요인으로 생태계의 44∼56%의 변화를 설명할 수 있었으며, 정점 6 에서는 영양염류가 중요한 요인이 됨을 알았다. 두번째 요인으로는 담수의 유입으로 볼 수 있었으며, 이 요인은 외해로 나갈수록 그 영향이 적어져, 정점 4 에서는 의미가 없었다. 질소의 유입도 각 정점에서 주요한 요인이었으며, 그 외에 유기물의 증가, 도시하수의 유입, 영양염류의 침전 및 미생물에 의한 염류의 재순환과 광합성이 진해만에서의 수질과 생태계를 지배하는 주요 요인으로 확인되었다. In Jinhae bay, the physicochemical, biological and ecological surveys were carried out 65times at six sites both insurface and bottom water from July 1976 to December 1982. Twenty one abiotic andbiotic parameters were determined on each sample. These data were subjected to factor analysis to scrutinize the effects of environmental conditions on water quality and ecosystem. The phytoplankto blooming was the major factor of the variance of the water quality and ecosystem in Jinhae bay. Fresh water inflow was second factor at site 1 and 6, and it was third factor in site 3 and 5. The nitrogen inflow was also play an improtant role, which was second factor at site 2, 3, 4 and 5, and third factor at site 1. Beside above factors, the increasing of organic materials, waste water in flow, precipitation and recycling of nutrients, upwelling of sediment, nutrient, salts and photosynthesis were also determined for the variation of water quality and ecosystem.

그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력

최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1

An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.

감마선 조사 랫트의 고환에서 fibronectin의 발현

정진우,김희철,김정태,안미정,이지영,신태균 제주대학교 방사능이용연구소 2005 방사선응용과학연구소논문집 Vol.19 No.-