퍼지집합을 이용한 표적식별융합 기법의 성능

강석훈,구자곤 대전대학교 산업기술연구소 2000 산업기술연구소 論文集 Vol.11 No.2

Multi-sensor data fusion is an emerging technology applied to military applications such as automatic identification, analysis of battlefield situations, and threat assessments. We can obtain more accurate and efficient meaningful information through multi-sensor data fusion that may not be possible from a single sensor alone. Especially, identification fusion is very important in order to estimate and correspond battlefield situation as well as analyze threat assessments. In this paper we present a novel heuristic identification fusion method using fuzzy set theory, because fuzzy set can deal with imprecise concepts mathematically via an extension of boolean set. We adopt desirable properties from not only parametric classification technique but also cognitive-based models in order to meet the realtime processing requirements.

Culex pipiens pallens 모기의 난성숙에 관한 연구

姜奭熙,이승훈 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.2

본 연구에서는 Culex pipiens 모기의 난성숙에 대한 Egg development neurosecretory hormone(EDNH)의 영향과 방출시기를 decapitation을 통한 in vitro fat body incubation과 rocket immunoelectrophoresis 방법에 의해 합성된 난황단백질의 정량과 follicle cell의 성숙정도를 측정하는 방법으로 조사하였다. C. pipiens를 흡혈 후 30분에 decapitation 하였을 때 follicle cell의 성숙은 25% 정도의 모기에서 일어났으며, 흡혈 후 1 시간에 decapitation한 모기에서는 90% 이상의 모기에서 난성숙이 일어났다. A. atropalpus 에서는 우화 후 6시간 이전에 decapitation하였을 때 follicle cell의 성숙이 일어나지 않았다. Decapitation후 in vitro fat body incubation에 의한 ^3H-protein과 ^3H-vitellogein의 정량결과에서도 C. pipiens는 흡혈 후 30분에 decapitation한 모기에서 난황단백질의 합성이 일어났다. 또한 흡혈 후 1시간에 decapitation한 모기에서는 12시간에 decapitation 한 모기와 비슷한 정도의 난황단백질의 합성이 일어났다. Decapitation 후 rocket immunoelectrophoresis 방법으로 난소내에 축적된 vitellin과 지방체내의 vitellogenin을 정량한 결과 흡혈 후 30분에 decapitation한 모기에서는 흡혈 후 18시간 지난 정상모기의 난소와 유사한 양의 vitellin이 축적되었으며, 흡혈 후 1시간에 decapitation한 모기에서는 흡혈 후 24시간 지난 정상모기의 난소와 유사한 양의 vitellin이 축적되었다. 또한 흡혈 후 30분에 decapitation한 모기의 지방체 내에서 10㎍ 이상의 vitellogenin이 합성된 것으로 관찰되었다. 이상의 결과는 흡혈 후, 또는 우화 후 6시간 이후부터 EDNH의 방출이 시작되는 것으로 알려진 A. atropalpus나 A. aegypti 모기와는 달리 C. pipiens 모기에 있어서는 흡혈 후 30분 정도만 되어도 뇌로부터 EDNH의 방출이 시작되어 난성숙에 필요한 난황단백질 합성의 시작을 자극하는 것으로 여겨진다. Synthesis of vitellogenin in the anautogenous mosquito, Culex pipiens pallens was examined by incubating the fat body in vitro. Vitellogenin synthesis began to occur at 6 hours after blood feeding, reached at maximum level by 24 hour, and was completed by 45 hours. Ovarian uptake of yolk was examined by measuring the amount of egg vitellin by rocket immunoelectrophoreisis. Ovarian vitellin level began to rise at 12 hour post blood meal and continued for up to 60 hours. Decapitation within 10 minutes after blood meal completely blocked vitellogenin synthesis by the fat body. When decapitation was performed at 1 hour post blood feeding, more than 90 percent o female produced mature eggs. These results are different from that of Aedes aegypti in which the critical period was found to be 6 hours post blood meal.

Flowable 및 microfill 복합레진으로 충전된 제 5급와동에서 load cycling 전,후의 미세변연누출 비교

강석호,김오영,오명환,조병훈,엄정문,권혁춘,손호현 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.2

Low-viscosity composite resins may produce better sealed margins than stiffer compositions (KempScholte and Davidson, 1988; Crim, 1989). Flowable composites have been recommended for use in Class V cavities but it is also controversial because of its high rates of shrinkage. On the other hand, in the study comparing elastic moduli and leakage, the microfil had the least leakage (Rundle et al. 1997). Furthermore, in the 1996 survey of the Reality Editorial Team, microfills were the clear choice for abfraction lesions. The purpose of this study was to evaluate the microleakage of 6 composite resins (2 hybrids, 2 microfills, and 2 flowable composites) with and without load cycling. Notch-shaped Class V cavities were prepared on buccal surface of 180 extracted human upper premolars on cementum margin. The teeth were randomly divided into non-load cycling group (group 1) and load cycling group(group 2) of 90 teeth each. The experimental teeth of each group were randomly divided into 6 subgroups of 15 samples. All preparations were etched, and Single bond was applied. Preparations were restored with the following materials (n=15) : hybrid composite resin [Z250(3M Dental Products Inc. St.Paul, USA), Denfil(Vericom, Ahnyang, Korea)], microfil [Heliomolar RO(Vivadent, Schaan, Liechtenstein), Micronew(Bisco Inc. Schaumburg, IL, USA)], and flowable composite[AeliteFlo(Bisco Inc. Schaumburg, IL, USA), Revolution(Kerr Corp. Orange, CA, USA)]. Teeth of group 2 were subjected to occlusal load (100N for 50,000 cycles) using chewing simulator(MTS 858 Mini Bionix Ⅱ system, MTS Systems Corp., Minn, USA). All samples were coated with nail polish 1mm short of the restoration, placed in 2% methylene blue for 24 hours, and sectioned with a diamond wheel. Enamel and dentin/cementum margins were analyzed for microleakage on a sclale of 0 (no leakage) to 3 (3/3 of wall). Results were statistically analyzed by Kruskal-Wallis One way analysis, Mann-Whitney U-test, and Student-Newmann-Keuls method. (p=0.05) Results: 1. There was significantly less microleage in enamel margins than dentinal margins of all groups. (p<0.05) 2. There was no significant difference between six composite resin in enamel margin of group 1. 3. In dentin margin of group 1, flowable composite had more microleakage than others but not of significant differences. 4. There was no significant difference between six composite resin in enamel margin of group 2. 5. In dentin margin of group 2, the microleakage were R>A=H=M>D>Z. But there was no significant differences. 6. In enamel margins, load cycling did not affect the marginal microleakage in significant degree. 7. In dentin margins, load cycling did affect the marginal microleakage only in Revolution. (p<0.05)

카드뮴이 인간 단핵구 세포주(THP-1)에서 cytokine 유전자 발현에 미치는 영향

신동훈,박관규,강미정,서석권,정인성,양선희 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

Cadmium, a potent toxic metal, posses a serious environmental threat but the mechanism of its toxicity remains unclear. Also, cadmium is a known immunotoxic agent in animal studies and induces pathophysiological effects by modulating components of immune system. Cytokines are being increasingly recognized as essential mediators of normal and pathologic immune response. Cells of mononuclear phagocytic system are strategically located at portals of entry in humans and therefore may be particularly at risk for cadmium exposure through contaminated air, food, and drinking water. In the present study, we investigated the effect of cadmium cytotoxicity for the monocyte and expression of cytokine gene in the control and cadmium treated human monocytic cell lines using RT-PCR method. The results showed that cadmium inhibited cell proliferation at 0.1mM cadimium treated cells for 24 hours. The TNF-α mRNA was expressed in both control and cadmium treated cells but not IL-6 and IL-1β. The mRNA levels of TNF-αwere examined during 24 hours culture period, at different time points. The expression of TNF-αmRNA increased in both 0.01mM and 0.1mM cadmium treated cells, but did not show dose-response relationship. According to cadimium treated duration, expression of TNF-αmRNA was more decreased in 24 hours than 6 hours. The decreased levels of mRNA of TNF-α suggest that cadmium suppresses its production at the transcription level.

인공 생명 기법을 이용한 로봇 군 지능 구현

민석기,강훈 중앙대학교 생산공학연구소 1998 생산공학연구소 논문집 Vol.7 No.1

본 논문의 목적은, 인공 생명의 원리에 따라 간단한 지역적 규칙으로부터 복잡한 전역적 지능을 형성하는 복수의 자율 이동 로봇의 창발적 행동을 유도하도록 하는 데 있다. 여기서, 강화 신호를 가진 신경 회로망의 학습 구조를 제안하여 이동 로봇이 집단을 이루어 이동할 때 주변의 정보를 센서로 인지하여 움직이는 방향과 속력이 결정되도록 하였다. 시뮬레이션 결과로써, 동적 환경에서 장애물 및 개체간의 충돌을 방지할 뿐 만 아니라 이동 로봇들이 여러 가지 형태를 유지하며 이동하도록 하는 신경 회로망의 최적 하중값을 실시간으로 구하였다. The objective of this paper is, based upon the principles of artificial life, to induce emergent behaviors of multiple autonomous mobile robots which form from simple local rules to complex global intelligence. Here, we propose an architecture of neural network learning with reinforcement signals which perceives the neighborhood information and decides the direction and the velocity of movement as mobile robots navigates in a group. As results of the simulations, the optimum weights are obtained in real time, which not only prevent from the collisions between agents and obstacles in the dynamic environment, but also have the mobile robots move and keep in various patterns.

신생아의 저칼슘혈증

이강일,남성지,이원석,이건수,구자훈 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.2

A clinical study about neonatal hypocalcemia utilizing Q-oTc interval was conducted on 174 sick babies and/or high risk infants from March 1980 to June 1981. Following results were obtained; Out of 43 hypocalcemic infants, 37 (86%) were early neonatal hypocalcemia and 6 (14%) late neonatal hypocalcemia. There was no sex difference noted. Affected rate in premature babies was 43% and low birth weight infants 36%. And in accordance with increasing gestational age and/or birth weight, the rate became gradually fallen. Poor sucking was the most common symptom of hypocalcemia occurring in 15 cases, followed by irritability, jitteriness and abnormal crying in 13, convulsion in 10, and vomiting, cyanosis and RDS in small number of cases. However, 14 hypocalcemic infants showed no symptom at all. The most common associated disorder was low birth weight, followed by "suspected sepsis", jaundice, asphyxia neonatorum, oral thrush, Placental dysfuntion, polycythemia, hypoglycemia, diarrhea, DIC, SIADH and partial type of DiGeorge syndrome, etc. At birth, abnormal maternal condition was seen in about half (48.8%) of the cases, these being toxemia, twin pregnancy, amnionitis, abruptio placenta, polyhydramnios, chronic hypertension and heart disease. Calcium therapy induced prompt response in the majority of cases, as normalization of Q-oTc interval in 50% and clinical improvement in 62% within 24 hours after starting calcium therapy, except 3 cases who expired due to severe complication such as sepsis, pneumonia and RDS.

추적조사를 중심으로 한 腰椎間板脫出症에 대한 蜈蚣藥鍼의 臨床的 硏究

최회강,소기숙,고강훈,박소영,김성남,이종덕,원경숙,문형철,김성철 大韓鍼灸學會 2003 대한침구의학회지 Vol.20 No.3

Objective : This study is performed for the purpose of examining the efficacy of the scolopendrid(Scolopendra morsitans L) which has been to low back pain as a folk remedy. Methods & Results : Seventy patints with H.I.V.D. treated with the scolopendrid aquacupuncture and examined 4 tests; D.I.T.I., physical test, Oswestry disability index, and self-conscious pain rate were studied. And we follow up after discharge, we evaluated the present state and recovery period. Or we evaluated by herniated type and duration of onset. There was 58~97% of efficacy rate in each tests. Moreover, statistically valuable change in all 7D.I.T.I. points and in disability index and in self-conscious pain rate was showed. Conclusion : The scolopendrid aquacupuncture is possible to be effective terating the H.I.V.D patients. so we suggest the possibility using this new remedy to the H.I.V.D. patients.

RAW264.7 세포에서 interferon-r 및 LPS에 의해 유도되는 NO생성에 미치는 TALT-35의 영향

박종일,박경석,김종석,박지훈,윤은진,송경섭,서강식,김훈,윤완희,박승길,임규,황병두 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

TALP-35 purified from human term placenta is known to increase microtubule polymerization and stabilize the polymerized microtubule. To examine the effect of TALP-35 on immune system this study was performed. MTT assay was performed to investigate the effect of TALP-35 on the proliferation of RAW264.7 cells. TALP-35 dose dependently suppress the proliferation of RAW264.7 cells at high concentration (above 1 μM) in unstimulated cells, in case of 10 μM TALP-35 treated cells the suppression was 25% but in stimulated cells it was only 15%. Cosedimentation assay was carried out to investigate whether TALP-35 can bind to tubulin of RAW264.7, monocyte/macrophage lineage of mouse, and polymerize it. TALP-35 polymerize the tubulin of RAW264.7 cells and sedimented in dose-dependent manner. To investigate the effect of TALP-35 on the expression of iNOS protein western blotting was performed. The expression level of iNOS was decreased dose dependently in high concentration of TALP-35 treatment. To examine the activity of iNOS, secreted NO was determined by method based on Griess reaction. Interferon-γ and LPS-stimulated production of NO from RAW264.7 cells was decreased dose dependently above 0.1 μM concentration of TALP-35 and 50% is decreased at 10μM of it. This study shows TALP-35 can control cytokine induced-iNOS expression therefore it might control inflammatory diseases.

Synthesis and Photoisomerization Properties of Polynorbornenes with Azobenzene Chromophores

Kang, Suk-Hoon,Shin, Hee-Deuk,Oh, Cha-Hwan,Choi, Dong-Hoon,Park, Ki-Hong Korean Chemical Society 2002 Bulletin of the Korean Chemical Society Vol.23 No.7

We successfully synthesized the addition-type polynorbonenes (PNB) exhibiting photochromic properties and excellent thermal stability. Three norbornene-based monomers with different azobenzene moiety (R=NO2, H,OCH3) were synthesized by transesterification method. The corresponding PNB copolymers were synthesized by transition metal-catalyzed addition polymerization method, and characterized by GPC, UV-Vis spectroscopy, NMR, and thermal analysis. For comparison of the photochromic properties depending on the rigidity of polymer backbone, we prepared the polymethylmethacrylate (PMMA) copolymer with the corresponding azobenzene moiety. We investigated the photoisomerization behavior by means of optical muitichannel analyzer with Xe lamp as well as real-time UV-Vis spectroscopy with high-pressure mercury lamp. Among three PNB copolymers, a polymer with azobenzene (R=H) was the most adaptable for observation of photoisomerization behavior. It was found that the rate of photoisomerization and relaxation depended on the structure of azobenzene chromophore, rather than that of polymer backbone.

Anisotropic Swelling Behavior of Hot-extruded Beryllium

Suk Hoon Kang,Jinsung Jang,김태규,Myung-Hwan Jung,Jae Sang Lee 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.8

The lifetime of beryllium reflector assemblies is usually determined by neutron irradiation induced swelling, which results in mechanical interferences or fractures of the beryllium elements. Therefore, the dimensional stability and microstructure variations of beryllium during irradiation are important issues to study. In this paper, the microstructure characteristics of S-200-F and EHP-56 beryllium blocks, which were manufactured by using vacuum hot pressing (VHP) and hot extrusion (HE), respectively, were investigated. BeO distributions, grain shapes, and preferred orientations were investigated by using SEM-EPMA and SEM-EBSD systems. Dissimilarly to S-200-F, a strong fiber texture developed in the EHP-56 during the HE process; the basal planes in the majority of grains were arranged along the extrusion direction. To emulate the microstructure evolution during neutron irradiation, we irradiated the electro-polished surface of EHP-56 with protons at room temperature, where the acceleration voltage and the number of protons were 120 keV and 2.0 × 1018 ions/cm2, respectively. Irradiation-induced cavities were observed to be considerably longer along the basal plane in the EHP-56 specimen. Correspondingly, the amount of dimensional change was smaller along the direction parallel to the basal plane.