바람에 의한 정사각주형 건물주위의 유동해석

서상호,노형운,심준완,이광열 崇實大學校 生産技術硏究所 1994 論文集 Vol.24 No.-

It is necessary to understand fully the effects of wind forces on buildings, specially high-rise buildings in a large city. Air flows around a cubic-shaped model are investigated experimentally in the wind tunnel and simulated numerically. Pressure distributions and the corresponding pressure coefficients are determined by the experimental results. The pressure distribution results are compared with the numerical analysis. The software of FLOW3D Release 3.2.1 is used for numerical analyses. The numerical results for pressure distribution are in fairly good agreement with those of experiments.

La_1.85Ba_0.15CuO_4-y에서 Cu 치환이 전기적 특성에 미치는 영향

서성완,최무용 성균관대학교 기초과학연구소 1994 論文集 Vol.45 No.1

산화물 고온초전도체 La_1.85Ba_0.15CuO_(4-y)에서 Cu를 전이금속 원소인 Co, Zn, Ni로 치환해 가면서 그에 따르는 열기전력과 비저항의 변화를 연구하였다. 이러한 전이금속 원소를 Cu 대신 치환했을 때 모든 경우 치환량이 증가할수록 임계온도는 급격히 감소한 반면 열기전력은 상대적으로 작은 변화를 보였다. 이것은 Zn, Co, Ni에 의한 임계온도 감소효과가 물질의 전자구조나 전도입자의 상태밀도 변화에 의한 것이 아님을 의미한다. 치환된 전이금속 원소들이 물질의 자기적 성질에 영향을 주는 가능성을 고려해 보았다. Thermopower and resistivity of La_1.85CuO_(4-y) with 3d transition metal atoms(Co, Zn, Ni) substituting for Cu were studied systematically as functions of the doping concentration. In all cases examined, T_ε decreases as the dopant concentration increases, but the thermopower shows little change in quantity. These experimental results indicate that the supression of superconductivity by transition metal atoms substitution in the material has not to do with change of the carrier concentration in the material. It is known that high-T_ε superconductivity has a close relation to antiferromagnetic ordering in CuO_2 plane. In this respect we take into consideration of the possibility that these 3d atoms may influence mangetic properties of the material.

우리나라 重要産業製品 流通構造의 近代化方案

李相道,金正子,宋瑞日,李相玩 동아대학교 공과대학 부설 한국자원개발연구소 1980 硏究報告 Vol.5 No.1

It needs the distributive facilities to perform efficiently the construction of distribution center for the improvement plan of physical distribution structure. In view of promoting distributive modernization and physical distribution cost reduction, the establishment of optimum scale by intensity and concerning of transportation is persued. These efficient arrangements of distribution center which can be organic combining facilities of a supplier and a demander are the urgent challenges. With a view to such distribution problems, the purpose of this paper is to concentrate the presentation of algorithm in selecting the optimal location of distribution center to build model for systematization and to obtain basic data on the design of distribution system in the future.

실물과 사진제시에 의한 화색과 식물형태의 비교 : focusing on the students of mental ratardation 정신지체학생을 대상으로

안기완,백지성,김은일,조희두,서성철,오찬교 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.4

This study was carried out to verify the differences in preference of flower colors by displaying flowered plants and their photos to mentally retarded students. As a result, normal students showed consistent preference against both the objects. But mentally retarded students had a different preference for flowered plants and their photos.

21세기 공공도서관 발전방향 및 모델개발연구

한상완,서혜란,곽철완 한국문헌정보학회 1997 한국문헌정보학회지 Vol.31 No.2

본 연구의 목적은 21세기를 대비한 공공도서관의 발전방향과 모형을 제공하는데 있다. 21세기 공공도서관을 위한 기본 개념은 공평한 접근성과 다양한 이용자 요구를 만족시킬 수 있어야 한다. 이를 위해 공공도서관은 봉사대상과 주제분야를 중심으로 체제가 이루어져야 하며 다른 도서관과 정보를 공유할 수 있어야 한다. 또한 직원은 교육, 연구, 실무경험을 기준으로 하여 자격증을 부여하고, 한 분야에 장기적으로 근무시켜 전문가를 양성하는 배치기준이 필요하다. 도서관 모형은 인구를 중심으로하여 대도시형, 중소도시형, 그리고 농촌 및 소규모형으로 구분하는 것이 바람직하다 The purpose of this study is to provide the development direction and model for the 21 century public library. The 21 century public library should have the accessibility for everyone and provide the satisfaction for all kind of information needs. For these, public libraries would be organized by type of users and topics and share the resources with others. Staff should be hired by the certification based upon education, research, and experience. For the models of public libraries, there were divided to three types: metro, medium, and small rural type of libraries

충북 남부지역 중소 제조기업의 경쟁력 제고를 위한 경영 및 애로기술 실태조사 연구

윤상원,구경완,정성진,백기영,김선훈,서용성,이근복 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 연구에서는 충북 남부 3개군 지역(옥천 · 보은 · 영동)의 중소 제조기업의 경영실태 및 애로기술을 대상으로 실증조사 되었다.·지역의 특정상황의 전제하에 지방 중소기업들의 실질적인 문제점들을 발견하고, 그 개선 방안을 탐색함은 물론 산 · 학 · 연 컨소시엄 사업의 성공적인 수행을 위해 시도되었다.세부적으로는 중소 제조기업의 경영 및 애로기술 특성을 일반적 사항, 경영애로요인, 경영전략, 현장개선기법, 정보화, 제품 및 공정 기술상의 애로기술 현황파악의 6개 영역으로 조사되었다. 조사결과들은 추후 산 · 학 · 연 공동기술개발 사업에 있어 창의적, 틈새적 과제발굴 및 신제품 기술개발의 토대마련이 될 뿐 아니라, 지역경제 발전을 위한 산 · 학 관의 지원 전략 수립에 적극 활용 될 것으로 판단된다.

결핵치료제인 시판 리팜피신제제의 생체내 이용율

김종두,안기완,서영환,조경상,김철,김상도,홍순표 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

This study was attempted to investigate the dissolution rate and the bioavailability of commercially available rifampicin preparations after oral administration in nine normal volunteers. Cross-over design was used for the analysis. The dissolution test was conducted in artificial gastric juice and artificial intestinal juice using basket method with four rifampicin preparations (A, B, C, and D) which were pharmaceutically equivalent. The results were as follows; The dissolution rate was higher in the order of A>C>B>D in artificial gastric juice, and A>B>C>D in artificial intestinal juice. Area under the blood concentration time curve (AUC) was larger in order of A>C>B>D. Relative bioavailability(%) of rifampicin preparations were 93.6% for B, 97% for C, 84.4% for D preparation compared with standard A preparation. Peak blood concentration (Cmax) was higer in order of A>B>C>D. Peak time (Tmax) was larger in order of D>C>A>B. Absorption rate constant (Ka) was larger in order of B>A>D>C. there was little difference in elimination rate constant and biological half-life. The correlation of the dissolution rate in artificial gastric juice and area under the blood concentration time curve as well as correlation of the dissolution rate in artifical intestinal juice and peak time showed significant linear relationship. From the result of the this experiments, it can be concluded that for the choice of preparations, bioavailability must be performed in man because the bioavailability of rifampicin preparations showed big differences among commercial preparations which were abvertised as pharmaceutically equivalent, and that the bioavailability of rifampicin preparations in man partially could be predicted from the results of dissolution rate.

내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

위암세포에 의한 종양침윤 림프구의 면역반응 억제기전에 관한 연구

박정규,송규상,서광선,최정목,배진선,장일성,윤완희,노승무,조은경,백태현 大韓免疫學會 1995 大韓免疫學會誌 Vol.17 No.3

Tumor-infiltrating lymphocytes ('1°ILs) interact most closely with tumor cells and thus are more likely to reflect tumor host interactions accurately. But it is unknown whether such T cells are nonspecific inflammatory cells or a subset of specific host immune responses. In this study, there was no clear correlation between the infiltration of T lymphocytes in stomach cancer and the overexpression of c-ErbB-2 or increasing class I MHC expression on tumor cells. A positive correlation was seen between the presence of TILs in the tumor and tumors with diploidy by flow cytometric DNA analysis. The proliferative responses of Ills stimulated with IL-2, anti-CD3 mAb, or both were examined. When compared to normal mucosal-associated lymphoid tissue lymphocytes, the proliferative response of TILs to high dose IL-2 was minimal. A similarly poor response to anti-CD3 mAb plus IL-2 was also observed. The freshly isolated TILs exhibit reduced ability to proliferate in response to IL-2, anti-CD3 mAb or both. The microenvironment of the tumor suppresses the proliferative capacity of the TILs. The mechanism of this suppression remains unknown. It could be mediated by suppressor cells, by soluble substances within the tumor, or both. To examine this question, supernatants of stomach cancer cells (SNSNU-1) were tested for the presence of immunosuppressive factors. Human peripheral blood T-cells and tumor-draining lymph node lymphocytes (TDLNL) were incubated for 3 days with SNSNU-1 and then assessed for proliferative responses to PMA, anti-CD28 mAb, or both and for the inducibility to express IFN- r or IL-4 mRNA to PMA. Peripheral blood T-cells pretreated with SNSNU-1 were unable to proliferate in response to PMA, anti-CD28 mAb or both. SNSNU-1 also produces inhibitory activities of TDLNL proliferative response to PMA or anti-CD28 mAb and PMA (49%, 52%, respectively). In contrast, culture supernatants obtained from HEp-2, K562 or Daudi showed normal proliferative responsiveness of peripheral blood T-cells and TDLNL by PMA, anti-CD28 mAb or both.

Helicobacter pylori 양성인 소화성 궤양 및 위염 환자에서 Helicobacter pylori 제균에 대한 판토프라졸 포함 삼제 요법의 임상효과 및 내약성에 대한 연구

서영호,이완식,주영은,김현수,최성규,유종선,김행재,서순팔,김세종 최신의학사 2000 最新醫學 Vol.43 No.11-12