응급실에서 기관내 삽관후 발생한 후두육아종 1례

조남수,김용배,조수형,송민엽,송성용 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1

Endotracheal intubation has been used widely for the maintenance of airway in the emergency patient and CPR in the acute airway obstruction patient and to treat respiratory insufficiency. Endotracheal intubation has many advantages but it may cause several complications which rate about 4% of endotracheal intubation patient. Among these complications, laryngeal granuloma is a relatively rare complication arising about 1 case per 10,000∼20,000 cases. Authors report a case of laryngeal granuloma which developed after endotracheal intubation required during emergency treatment. Case: A 55-year old female patient visited Chosun University Hospital Emergency Room complaining of dyspnea, cyanosis and sweating on Feb. 8th 1995. According to past history, she had a little obesity, dyspnea on exercise and mild hypertension. At arrival, blood pressure was 240/110mmHg, pulse rate 150 rates/min, respiratory rate 12/min, body temperature 36.5℃ and cyanosis with sweating on whole body was observed. And the mental state was semicoma. At 5 minutes after arrival, sudden respiratory arrest developed and immediate endotracheal intubation which emergency treatment was performed it was difficult to intubate endotracheally due to short neck and obesity. At 1 hour after arrival, general condition of the patient recovered well and extubation was done. The patient was transferred to internal medicine department and discharged after 12 days of medical treatment. At 2 months after discharge, the patient felt a progressive hoarseness and foreign body sensation of larynx. She was diagnosed as laryngeal granuloma at ENT department of Chosun University. She underwent the surgical operation and discharged in good health after 7 days of admission.

Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

심혈관 위험요인과 청력역치의 상관성

조영채,이태용,이동배,정성필,김수영 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

To investigate the effects of cardiovascular risk factors on hearing loss, hearing threshold and cardiovascular risk factors such as blood pressure, hematologic values, and serum lipid levels of 3,827 persons who visited the Health Center of a University Hospital in Kumi for health examination from January 1, 1995 to July 31, 1997 were analysed. The results were summarized as follows; 1. Hearing threshold was shifted highly in both sex groups with age increased. Smoking did not influence increase of hearing loss, but drinking alcohol amount increased the hearing threshold when sex was adjusted. The most highly increased hearing threshold showed among farmers group, but next was blue collars group. Hearing threshold increasing basis with BMI increased. 2. Systolic and diastolic blood pressure and hematocrit value increased the hearing threshold in both sex groups, but hemoglobin value did not related to the hearing threshold. 3. Total cholesterol, LDL-cholesterol, triglyceride, and atherosclerosis index were significantly increased with the grade of hearing loss increased, when age was adjusted. 4. In the logistic regression analysis, the atherosclerosis index, age, and hematocrit value revealed risk factors which contributed in that orders, though the values were small they showed statistical significaces, but the risks were lowered when hemoglobin values increased, in both sex groups. Consequently, hyperlipidemia was significantly related to the hearing loss when age was adjusted.

우리나라 연 작업자들의 연폭로 수준에 관한 연구

조인숙,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

To assess lead exposure in Korean lead workers, 2047 male lead workers in 17 lead using industries were studied. Study population were divided into 4 occupation categories such as storage battery industry(type 1), secondary smelting and litharge making industries(type 2), PVC stabilizer making industries(type 3) and primary smelting and related industries (type 4). Blood lead and zinc protoporphyrin in whole blood (ZPP) were selected as an index of lead exposure. Hemoglobin and hematocrit were also checked. Fifteen questionnaires of lead related symptoms were provided to all lead workers and filled up by themselves and confirmed by medical doctors. Personal variables such as age, work duration, smoking and drinking habits were also collected. the results were as follows. 1) The mean blood lead, ZPP and hemoglobin of all lead workers were 29.7+12.6㎍/100㎖, 56.5+38.6㎍/100㎖ and 14.6+1.3 gm/100㎖ respectively. 2) While the mean blood lead of lead workers in type 1, 2, 3 and 4 were 28.6+11.6㎍/100㎖, 46.2+15.3 ㎍/100㎖, 46.8+12.1 ㎍/100㎖ and 26.2+10.2 ㎍/100㎖, the mean value of blood ZPP of those workers were 53.6+32.6 ㎍/100㎖, 108.1+87.1 ㎍/100㎖, 98.9 +54.9 ㎍/100㎖ and 45.8+19.5 ㎍/100㎖ respectively. 3) The percents of lead workers whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 17.6% and 2.1% respectively. Those whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 15.18% and 0.96% for type 1, 43.59% and 21.79% for type 2, 58.89% and 12.22% for type 3 and 11.82% and 0% for type 4 respectively. 4) The percents of lead workers whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 5.17% and 3.17% respectively. Those whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 4.66% and 2.04% for type 1, 10.26% and 25.64% for type 2, 23.33 and 13.33% for type 3 and 1.28% and 0.32% for type 4 respectively. 5) The prevalence rate of smoking and drinking of male lead workers in all lead industries were 70.8% and 71.0% respectively. While the mean blood lead of smoker, non-smoker, drinker and non-drinker were 30.24+12.58 ㎍/100㎖, 28.35+12.7 ㎍/100㎖, 30.24 ㎍/100㎖ and 28.74 ㎍/100㎖ respectively, the mean blood ZPP of those were 55.7+37.1 ㎍/100㎖, 58.4+41.9 ㎍/100㎖, 55.7+36.5 ㎍/100㎖ and 58.4+43.3 ㎍/100㎖ respectively. 6) While the correlation of hematocrit corrected blood lead with other lead exposure variables were higher than non-corrected blood lead, the correlation of log-transformed ZPP with other lead exposure variables were higher than non-corrected blood ZPP. 7) The most frequent symptom among 15 lead related symptom questionnaires was 'general fatigue' and the next one was 'feeling irritated with disturbance' and least one was 'acute abdominal pain around the umbilicus' in all lead workers. The overall prevalence of lead workers in storage battery industry and primary lead smelting industry were higher than secondary lead smelting and PVC stabilizer making industries. 8) The prevalence of lead related symptoms was a little higher in 13 symptoms in smokers than non-smokers and in 14 symptoms in drinker than non-drinkers, but they were not statistically significant. 9) Stepwise multiple regression analysis, using overall symptom prevalence as a dependent variable blood lead, blood ZPP, hemoglobin, age, work duration, drinking and smoking habits as independent variables, indicated that smoking habit, drinking habit and age were significantly contributed to the dependent variable. 10) The slopes of simple linear regression of blood lead (independent variable) with blood ZPP and log-transformed ZPP as dependent variable were different among 4 types of lead industries. The slope of lead industries with low mean blood lead were less steeper than those with high mean blood lead.

치과기공실의 작업공정별 소음에 관한 연구

조수열,남상룡 효성여자대학교 부설 한국환경위생연구소 1992 환경위생연구 Vol.2 No.1

본 연구는 치과기공실의 작업부서별, 1인작업시의 소음도를 조사하여 기본자료로 하고 복합공정시의 소음을 측정하여 70 dB이상의 소음 노출시간을 조사함으로서 전체 치과기공실의소음도를 추정하고, 치과기공실의 소음이 치과기공사에게 정신적, 정서적 , 생리적으로 어떠한영향을 미치는가를 설문조사하여 소음에 노출되어 있는 치과기공소의 환경위생 관리와 건강장해를 예방하기 위한 기초자료를 얻고자하는데 그 목적이 있으며 그 결과는 다음과 같다. 1. 작업부서변 1인 공정시 소음도는 각 작업부서별 모두 연마작업시 높은 수치를 나타냈으며, 그 정도는 70 dB이상이다. 2. 작업부서별 복합공정시 공정별 소음도는 1인 작업공정시보다 전체적으로 소음발생이증가하였는데, 소음도의 차이는 연마시보다 조용한 작업공정 시가 최소한 10 dB이상으로더 큰 차이가 나타났다. 3. 작업부서별 소음 노출시간은 80 dB이상에서는 복합공청시 도재기공부서(150분), 국부의치(120분), 관교의치기공(100분), 총의치기공(80분) 순으로 나타났다. 4. 작업실의 시간대변 소음정도는 연마작업시는 대부븐이 80 dB이상이고 Wax작업시는대부분이 75 dB이하로 나타났다. 5. 설문조사에서 치과기공사의 심리적 상태는 기공실 소음으로 인하석 거의 매일 짜증난다(14%), 가끔씩 짜증난다(29%)로 나타났고 정서적 불안감도 화가 잘 난다(19%)로나타났다. 6. 소음이 치과기공사의 신체에 미치는 영향은 기공일을 하는 동안 위장병에 대해서는위산과다 39%, 위궤방 11%, 위염 5%, 십이지궤양 3% 순으로 나타났고, 심장이 약한것 같다가 32%로 나타났다. 7. 소음이 치과기공사의 청력에 미치는 영향은 약해진다가 39%, 보통이다 33%, 정상이다14%로 나타났다. 치과기공실에서 발생되는 소음에 의해 치과기공사들이 심리적, 신체적으로 큰 영향을 받는것으로 나타났으므로 치과기공실의 작업환경관리에 대해 보다 많은 관심이 요구되며, 소음의발생을 줄일 수 있는 지속적인 연구가 요망된다. Degree of noise by personal dental laboratory working process anddegree of noise by complex dental laboratory working process were measuredseparately. The time of exposure to noise greater than 70 dB estimated on thebasis of afore-medntioned information. Questionarire were employed to investi-gate the mental, emotional and physiological effects of noise on dental techni-cians. The purpose of this study was to provide basic information on keepingdental technicians who are exposed to noise pollution in good working conditionand good health. Results obtained are as follows ; 1. Polishing process in each working part showed high degree of noisegreater than 70 dB in terms of degree of noise by personal working. 2. Degee of noise by complex working process in each workong part wasgreater than that of personal working process. 3. Time of exposure to noise complex working process the part of porcelain150 min., partial denture 120 min., crown and bridge 100 min., full denture80 min. 4. Degree of noise by time in dental laboratory was 80 dB in general forpolishing process and below 75 dB for waxing process. 5. Effects of noise on mental and emotional state of dental technicians she-wed that they felt irritated every day(14% ), irritated once in a while(39% ) andeasily get med(19% ). 6. Effects of noise on heart and stomach were hyper-gastric acid(38% ) ,gastric ulcer(11% ), gastritis(5% ), deuodenal ulcer(3% ) and weak hert function(32% ). 7. Effects of noise on the hearting ability were weak(39% ), moderate(33% )and normal(14% ). Data presented in this study demonstrated that noise in the dental laboratoryexerts profound effect on detal technicians mentally, physiologically and emotio-nally. In light of the above results, therefore, it appears advisable to devote subs-tantial interests on the management of working condition and put further(conti-nuing) effeorts in the ivestigation for reducing noise problem.

Polytrop Blue B에 依한 徵量 Ti의 吸光度定量에 關한 硏究

趙誠烋,鄭鐘南,金英洙 朝鮮大學校 工科大學 1974 論文集 Vol.3 No.-

Polytrop Blue B Was proved to help determine Spectrophotometrically even little bit amount of titanium from 0.02 to 1.6 ppm. We dropped 5ml of 4.8×10??M polytrop Blue B solution in to 30ml of the titanium solution, and that PH was adjusted to 3.20 with o.25M sodium acetate solution and 0.25M perchloric acid. After the dilution to 50ml with water, we measured the absorbance at 573mμ. 3hours' standing did not change a bit in the absorbance. Interference was noticed from iron, aluminum, Oxalate ion very small amount of E D T A. The mole ratio of titanium to polytrop Blue B. in the complex under given condition was 1 : 1.

항공사 기업이미지전략에 관한 연구 (Ⅰ) : 하드웨어적 이미지 전략을 중심으로

조용수,박경권 진주여자전문대학 1996 論文集 Vol.19 No.-

This study is concerned with the corporate image strategy of aviation company. Greater focus on this study has brought attention to corporate advertising. The corporate image strategy of aviation company may be divided into two types : software and hardware. the focus of this study is hardware image strategy and theoretical background is the theory of cognitive responses. On this basis, three image strategies of contribution to the corporate advertising are classified. 1) image strategy according to preemptive strategy, 2) image strategy by convenience, 3) image strategy by economic appeal. And then, field cases are presented. Each of these cases have a related advertising strategy. Finally, based on these case study, some guidelines are recommended for corporate manager involved in corporate advertising and further research directions are discussed

대기압 스트리머 코로나방전특성 및 이산화탄소 전환특성

조문수,김학규,곽동주,신용섭 경성대학교 공학기술연구소 2001 공학기술연구지 Vol.8 No.-

Deep interests have been paid on the application of non-thermal plasma technique th solve the environmental pollution problems. CO_2 is one of the severe pollutants which cause the acid rain and global warming. In this study, in order to improve the conversion efficiency of CO_2, the streamer corona discharge plasma and barrier discharge plasma reactors were made, and the conversion characteristics of CO_2 by the corona discharge plasma and some discharge characteristics of these discharge chambers are studied experimentally.