AM 라디오 방송국 송신소 인근 지역의 암 발생률

임형준,하미나,조수헌 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.3

목적 : 본 연구에서는 의료보험 청구자료, 인구센서스 자로를 이용하여 방송극 송신소 주변 지역 주민들에서의 전자파 노출과 악성림프종, 백혈병, 뇌암, 유방암 등의 암 발생과의 관련성을 연구하고자 하였다. 방법 : 출력이 100 Kw 이상인 라디오 방송국 송신소의 반경 2 km 이내에 위치한 10개의 지역을 전자파 노출지역으로 선정하고, 각각의 노출지역에 대해 비슷한 인구규모의 방송국 송신소가 없는 네 개의 대조지역을 선정하였다. 1995년에 시행된 전국민 인구센서스 자료와 1993년 11월부터 1996년 10월 사이의 기간동안 청구된 의료보험자료를 인용하여 연구 대상 지역의 인구 분포와 악성림프종, 백혈병, 뇌암, 유방암의 진단명으로 진료를 받은 사람에 대한 정보를 얻었으며, 이를 이용하여 노출지역과 대조지역의 해당 암의 표준화발생비를 구하여 유의성을 검정하였다. 결과 : 총 10개 지역중 백혈병의 경우 한 지역에서 발생률의 유의한 증가를 그리고 다른 한 지역에서 발생률의 유의한 감소를 보였고, 뇌암의 경우 한 지역에서 발생률의 유의한 증가를 보였으나 그 이외의 지역에서는 일관된 결과를 보이지 않았다. 악성 림프종 및 유방암의 경우 연구 대상지역 모두에서 발생률의 유의한 차이는 없었다. 결론 : 본 연구는 향후 보다 분석적인 연구 수행을 위한 전단계의 생태학적 연구형태를 취하고 있어 본 연구 결과로서 전자파와 암발생간의 인과관계를 명확히 할 수 없다는 한계점을 가지고 있다. 전자파와 암발생과의 관련성을 연구하기 위해서는 본 연구에서 파악된 노출지역과 대조지역의 연구대상자에 대한 교란변수 및 보다 정교한 전자파 노출 정보등을 파악하여 환자-대조군 연구형태와 같은 분석적인 연구를 수행하는 것이 필요하리라 생각된다. Objectives : Several studies have raised the possibility that exposure to electrical and/or magnetic fields may be particularly harmful in the promotion or initiation of cancer. The purpose of this study which was based on a geographical correlation design was to investigate any association that may exist between residing near radio broadcast towers and carcinogenic activity in Korea. Methods : In this study, the health effects of EMF of 10 AM radio broadcast towers in Korea were investigated. The electric powers of the towers were above 100kW. We chose exposed areas that were located within 2 km from the towers as well as four control regions which had similar populations in the same province(Do) but had no towers nearby. The incidence of leukemia, malignant lymphoma, brain tumor and breast cancer between the exposed areas and the control areas was compared. The standardized incidence ratios(SIRs) were calculated. Korean Medical Insurance data(between Nov, 1, 1993 and Oct, 31, 1996) was used for the cancer incidence estimation. The Nationwide Population Census data(in 1995) and the Resident Register data(in 1995) were used for information about population and locations. Results : Among the 10 exposed areas, one area for leukemia and one area for brain tumor showed a significantly high incidence compared to the control areas. There were no significant increased areas for malignant lymphoma and breast cancer. Conclusions : This study design must be considered to be exploratory and not used for determining causality. However, the results suggest the necessity for further analytical epidemiological studies that have a more precise exposure measurement scale and information on confounding factors.

대기오염과 천식증상에 의한 응급실내원과의 연관성에 관한 환자교차연구

임형준,이상윤,윤기정,주영수,강대희,조수현 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : This study, using case-crossover design, search a relationship between changing levels of air pollutants and asthma attack in asthma patients. Methods : We searched the daily total number of asthmatic patients at hospital's emergency room in Seoul, Korea by investigating total 49 general hospital's emergency room records. Otherwise, We investigated medical records of asthmatic patients at one of the 49 hospitals we have searched. We investigated addresses that they are living, diagnosis, smoking history, whether respiratory infection or not, medications. We analyzed the data by 1:m conditional logistic regression used when matched case-control study is analyzed. Control periods were chosen by bidirectional paired matching technique 7, 14 days before and after case periods. Results : the relative risk of asthmatic attack by 100 ppm ozone increase between June and September were 1.348(95 % CI = 1.010∼1.619). Between November and February, the relative risk by 100 ㎍/㎥ TSP increase, 100ppb sulfur dioxide and nitrogen dioxide were respectively 1,278(1.010∼1.619), 1.237(1.019∼1.502), 1.285(1.006∼1.640). In stratified analysis, the relative risk were significant when the asthmatic patients were children aged 15 years or below, when there were respiratory infection, and when the patients took medications irregularly Conclusions : There was statistically significant association between ambient levels of air pollutants and asthmatic attack. So, we have to exert our efforts to minimize the air pollution effectively, to protect public health from air pollution.

의복구성학의 연구주제 및 경향분석

이정순,나수임,배주형 복식문화학회 2001 服飾文化硏究 Vol.9 No.2

The purpose of this study is to recognize the real situation of clothing construction to present the desirable direction to establish more scientific and reasonable themes of the study by analysis of the tendency of the clothing construction study. For this purpose, 402 papers on the theme of clothing construction study were excerpted from the first issues to the issues of December in 1999 of Journal of Korea Society of Clothing and Textile, Journal of Korea Home Economics, Journal of the Korean Society of Costume, Research Journal of the Costume Culture, Journal of the Korean Fiber Society, and Journal of the Human Engineering Society of Korea, I analyzed and classified the theme into eight issues of design related clothing construction, study of body types, study of patterns, size of apparel, fitting of clothing, protective clothing and functional clothing, sewing, and the others. The result of the study is as follows. 1. The distribution tendency of the clothing construction study by the journal of each society showed that Journal of Korean Home Economics is 22.9%, Journal of Korea Society of Clothing and Textiles 17.3%, Research Journal of the Costume Culture 12.2%, and Journal of the Korean Society of Costume 6.2%. 2. The distribution tendency of the studying issues showed that study of body types is 29.4%, study of patterns 21.9%, fitting of clothing 11.7%, sewing 10.2%, size of apparel 8.5%, and others 7%, protective clothing and functional clothing 6.7%, and design related clothing construction 4.7%. Considering the above result, we can understand that study of body types and patterns are being studied most actively. 3. Regarding the study tendency by academic issues showed that study of construction elements and design application is chiefly centered of the study of design related clothing construction (35.5%), analysis of body types is centered of the study of body types (46.6%), CAD is centered of the study of patterns (31.1%), and size spec for the ready made patterns is centered of the study of size of apparel (32.4%). As for fitting of clothing, the study was performed in two ways on the changes of the surfaces of human bodies in motion and the functional features of experimental dressing. Regarding the study of sewing, study of fusible interlining was mainly performed (36.6%) and regarding the study of protective clothing and functional clothing, study of brassieres and underwear was chiefly performed. Key words : design related clothing construction(디자인관련 의복구성), study of patterns(의복 및 패턴 연구), size of apparel(의류치수), fitting of clothing(의복의 맞음새), protective clothing and functional clothing(특수복 및 기능복).

한국의류학의 연구경향분석 : 1991~1999

나수임,이정순,배주형 복식문화학회 2000 服飾文化硏究 Vol.8 No.6

This study is planned to present the future direction of the study of Korean clothes through the realistic recognition of the changes of studying issues of each area of the related clothes. For this purpose, the writer of this thesis have collected, classified and analyzed those various kinds of papers and theses published in the professional magazines of clothes such as Journal of Korean Home Economics, Journal of the Korean Society of clothing and Textiles, Journal of the Korean Society of Costume, The Research Journal of the Costume Culture so that I might examine and study the main trend of the related study. The result of the study is as fallows. 1. Since the first publication of Journal of Korean Home Economics in 1959 and Journal of the Korea Society of Clothing and Textiles, and Journal of the Korean Society of Costume, the study of clothes has been gradually increased. Furthermore, since 1990 the issuing times of various kinds of Journals have been continuously increased with the foundation of The Research Journal of the Costume Culture and Journal of Fashion Business. 2. Theses and papers published in the four greatest Journals of Korean Clothing and Textiles have been studies for the detailed classification and analysis of the data. According to the study, It is found that the theses in Journal of the Korea Society of Clothing and Textiles have actively studied textiles as they had studied before 1990s and those in Journal of the Korean Society of Costume have studied history of costumes and those in The Research Journal of the Costume Culture have studied costumes cultures and those Journal of Korean Home Economics have studied the composition and science of clothes. 3. The order of studying subjects was 1) Design and Aesthetics, 2) Fashion Merchandising 3) Textiles, 4) Clothing Construction, 5) History of Costumes, 6) Costume Culture, 7) Socio -Psychology of clothing, 8) Others. Considering the above mentioned result of the study, most of the main fields of the clothing and textiles study have been studied continuously in balance since 1990 unlike the past although the past studies had been performed largely in some main fields only. And it was found that fields of clothing styles and clothing goods have been studied most actively since 1990s. 4. The studying field of Design and Aesthetics has showed to have the trend to be studied very actively since 1990s, which has utilized various relevant data with scholastic approach to psychology and aesthetics. Regarding Fashion Merchandising, the study of consumers decision process has been performed most actively. And theses on the international trades have been published considerably more than ever before, which resulted in gradual increase in the study of the fields related with global marketing, internet marketing, textile products exports, and overseas brands, etc. Regarding Textiles, the field of clothing sanitation and management has been studied more actively than that of clothing materials. In case of clothing construction, the study of physical styles and pattern making has been more active than the other related fields. Fields of socio-psychology of clothing and history costume have been a little reduced. Field of costume culture has been firmly rooted as an independent subject to be studied in the clothing rotated study. And study of the clothes has shown various trends of studies of ethnic & folk clothes, religious and ceremonial garments, linguistic & favorite approach to clothes and academic analysis of the data.

Glutamate 억제제가 Pilocarpine에 의한 경련 및 기억장애에 미치는 영향

천임순,한형수,박정숙,정헌주,이만기,김중영 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.3

목적 : Pilocarpine에 의한 경련 및 기억력 저하에 glutamate 수용체가 관련이 있는지 검토하였다. 대상 및 방법 : 생쥐에 pilocarpine을 투여하여 야기되는 경련 및 기억력저하가 glutamate 수용체 길항 약물인 MK-801 및 NBQX를 전처치하였을 때의 반응을 Morris Water Maze의 방법으로 관찰하였다. 결과 : MK-801과 NBQX를 전처치하고 pilocarpine을 투여하였는 바 pilocarpine에 의한 경련유발은 억제되지 않았으나, pilocarpine에 의한 reference memory와 working memory의 저하는 MK-801이나 NBQX를 처치로서 억제되었다. 결론 : Pilocarpine에 의한 경련작용에 비하여 기억력저허가 glutamte 수용체와 관련이 있는 것으로 보인다. The role of glutamate receptors in the genesis of pilocarpine-induced seizure and seizure-related memory deficit was studied using MK-801 and NBQX. After pretreatment with MK-801 or NBQX, pilocarpine was administered intraperitoneally. Both drugs had no effect on the behavioral seizure activity and onset of seizure activity. Memory was tested with reference and working memory version of Morris water maze at 20th day after pilocarpine treatment. Reference and working memory deficit was produced by pilocarpine. These deficit were prevented by MK-801 or NBQX, which were given in once a day for 4 day at 7th to 10th days after pilocarpine treatment. These results show that although MK-801 and NBQX do not have anticonvulsant property they can prevent pilocarpine-induced memory deficit.

일부 한국인의 혈청 ceruloplasmin 정상 참고치 설정 및 질환별 비교 : Comparison of Its Level among Various Diseases

이동수,박애자,박정덕,장임원,홍연표 중앙대학교 의과대학 의과학연구소 1999 中央醫大誌 Vol.24 No.1

Ceruloplasmin has been investigated as one of the useful biologic index for early diagnosis of atherolsclerosis. However, there was no normal reference value taking into account the confounders in Korea. This study was performed to estimate the normal reference values and present the confounders of ceruloplasmin. Also we compared of serum ceruloplasmin levels among normal reference group and three abnormal groups: 475 healthy subjects, 53 liver dysfunctions, 72 positive test of chronic inflammatory diseases, and 89 hypercholesterolemias. Mean serum ceruloplasmin level of healthy subjects were 41.6±7.6㎎/㎗ in males and 42.1±7.2㎎/㎗ in females, respectively. It was tend to increase of ceruloplasmin by age in both sexes. However, the statistical difference was not found by age group between both sexes. Statistically significant correlations were found between serum ceruloplasmin and age, body mass index(BMI), white blood cell(WBC) and triglyceride(TG) in males and age, BMI, WBC and total cholestrol(TG) in females. After adjustment for age, BMI,WBC and TG in males and age, BMI, WBC and TG in females, significant elevations of serum ceruloplasmin were found in liver dysfunction(p=0.0077) and positive test of chonic inflammatory disease(p=0.0217) in males and in oisitive test of chronic inflammatory disease(p=0.0023) and hypercholestolemia(p=0.0124) in females relative to healthy reference subjects. There is no statistical difference among liver dysfunction, postive test of chronic inflammatory disease, and hypercholesterolemia.

람블편모충(Giardia lamblia) 감염에 있어 면역학적 진단법의 가치에 관한 연구

金禎洙,任敬一,李根泰 연세대학교 의과대학 1982 연세의대논문집 Vol.15 No.2

Heparin이 망내계세포에 미치는 영향에 관한 초미형태학적 연구

이동철,김중길,임정교,손윤경,서인수,손태중 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.3

저자들은 heparin 투여후 세망내피계의 초미형태학적 변화를 관찰하기 위해 Sprague-Dawley계 숫쥐에 heparin과 endotoxin을 투여한 후 비장을 채취하여 실험에 이용하였다. 실험군은 heparin 전처치군과 heparin 후처치군으로 나누었으며 비교군으로 heparin 단독투여군과 endotoxin 단독투여군을 설정하여 각각을 투약후 비장을 채취하여 광학현미경 및 전자현미경적 검색을 실시하였다. 실험결과를 요약하면 heparin 단독투여군은 대식세포, 형질세포양 림프아구 및 다핵백혈구가 증가되었고, 대식세포의 탐식능도 항진되었다. 그러나 대식세포자체의 소기관 발달은 현저하지 않았다. Endotoxin 단독투여군은 시간이 갈수록 대식세포의 탐식능이 저하되고, 파괴가 증가되어 수가 감소하였다. 미소혈전이 자주 관찰되었으며 기타세포들의 파괴가 관찰되었다. Heparin 전처치 및 후처치군은 공히 endotoxin군에 비해 대식세포 탐식능이 증가되었다. 이상의 성적으로 보아 heparin의 망내세포에 대한 영향은 주로 대식세포의 탐식능과 수의 증가로 생각되며 이는 정상 및 병적상태 모두에서 일어난다고 생각된다. 또한 ET 투여 전후 heparin을 투여한 실험군에서 공히 대식세포 탐식능이 증가되었으므로 이는 ET shock 후 조직손상으로 분비되는 세망내피계 저하물질에 대해 heparin이 길항작용을 할 것으로 생각된다. 또한 heparin의 대식세포 탐식능항진에 대한 효과는 세포의 직접적인 자극이라기 보다는 탐식과정중 특히 oposonization에 효과를 미칠 것으로 생각된다. The authors studied an ultrastructural changes of reticuloendothelial system after administration of heparin. Male Sprague-Dawley rats were examined after administration of heparin and endotoxin. The experimental groups were divided into heparin pretreated groups and heparin posttreated groups. The control groups were divided into heparin-only groups and endotoxin-only groups. Each animals were sacrificed and spleens were extirpated and examined by light and electron microscopy. The results obtained were summarized as follows: Heparin-only groups showed proliferation of macrophages, lymphocytes and neutrophils. The phagocytic activity of marcophage is enhanced. The cytoplamic organellar change is not remarkable except increase of secondary lysosomes. Endotoxin-only groups showed decrease of phagocytic cells. The phagocytic activity is also depressed. Destruction of macrophages and other cells are noted. Microthrombi are frequently seen. Both heparin pretreated and heparin posttreated groups revealed relative enhancement of phagocytic activity compaired to endotoxin-only groups. From the result of the experimental study, it appears that the effect of heparin on the reticuloendothelial system is enhancement of phagocytic activity of macrophages both in the coditions of normal and pathologic one. And it also suggests that heparin may act as an antagonizing factor to the reticuloendothelial depressing agent that may be derived from injured organ of endotoxin shock. And the effect of heparin to the phagocytic activity of macrophage may be related to the process of phagocytosis such as opsonization or to the direct cellular stimulation.

新入生 意識構造의 調査를 기초로 한 學生 生活의 새로운 指導方法

최완식,전창수,윤정임 한국항공대학교 1993 論文集 Vol.31 No.-

이 硏究는 1992학년도의 한국항공대학교 신입생 의식구조의 조사를 토대로 한 새로운 학생생활지도 방안을 設定하기 위해서 마련된 것이다. 특히 이 연구의 진행과정에서는 최근 東北아시아의 국제정치 및 경제사정등의 극적인 變化가 학생생활에 미치는 영향 도 깊이 고려하였다. 뿐만 아니라 지난 오랜동안 한국항공대학교가 위치한 이 캠퍼스지역에 가로놓인 많은 어려운 장애 물과 악조건들이 학생들의 학습활동이나 연구생활에 미치는 악영향등도 충분히 유의하였다. 이 硏究의 두번째 목적은 무엇보다도 학생들의 進路지도를 적극 강화하고 보완하는 방안이 생활의 勉學분위기를 조성 하고 활기찬 학습 및 연구생활에 더욱 크게 이바지 하게 될 것이라는 점을 크게 유념하였다. This study is to eatablish "New Directions of Guidance for Students Life on the Basis of Research into Freshmen's Way of Thinking(1992)" in Hankuk Aviation University. In the process of this research, Particularly, we have deeply considered into the great influence upon the students life from the recent dramatic change of international polities and economic circumstances of Northeastern Asian countries. On the other hand, we have kept in mind very difficult conditions and circumstances laid in this campus area which have greatly influenced upon the very hard and inconvenient studing life of students for a long time past. The second objective of this research is to study of New Directions of Guidance for Making New job of Graduates and future new plan for variable social life after graduation. We believe such methods of New Guidance will remarkably devote on the effective and industrious studing life of students of Hankuk Avation University.

폐모세포종 : 1례보고 A Case Report

최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.