Percutaneous two unilateral iliosacral S1 screw fixation for pelvic ring injuries: a retrospective review of 38 patients

( Whee Sung Son ),( Jae-woo Cho ),( Nam-ryeol Kim ),( Jun-min Cho ),( Nak-jun Choi ),( Jong-keon Oh ),( Hanju Kim ) 대한외상학회 2022 大韓外傷學會誌 Vol.35 No.1

Purpose: Percutaneous iliosacral (IS) screw fixation for pelvic ring injuries is a minimally invasive technique that reduces the amount of blood loss and shortens the procedure time. Moreover, two unilateral IS S1 screws exhibit superior stability to a single IS screw and are also safer for neurological injuries than an S2 screw. Therefore, this study aimed to evaluate fixation using percutaneous two unilateral IS S1 screws for pelvic ring injuries and its subsequent clinical outcomes. Methods: We retrospectively reviewed 38 patients who underwent percutaneous two unilateral IS S1 screw fixation for pelvic ring injuries. The procedure time, blood loss, achievement of bone union, radiological outcomes (Matta and Tornetta grade), and postoperative complications were evaluated. Results: The mean procedure time, hemoglobin loss, bone union rate, and time to union were 40.1 minutes (range, 18-102 minutes), 0.6 g/dL (range, 0.3-1.0 g/dL), 100%, and 153.2 days (range, 61-327 days), respectively. The Matta and Tornetta grades were excellent, good, and fair in 24 (63.1%), 11 (28.9%), and three patients (7.9%), respectively, and the postoperative complications were S1 screw loosening, widening of the symphysis pubis (2.3 and 2.5 mm), lumbosacral plexopathy, and S1 radiculopathy in one (2.6%), two (5.3%), one (2.6%), and one patient (2.6%), respectively. However, all neurological complications recovered spontaneously. Conclusions: Percutaneous two unilateral IS S1 screw fixation was useful for treating pelvic ring injuries. In particular, it involved a short procedure time with little blood loss and also led to 100% bone union and good radiological outcomes.

Efficacy of Open Debridement and Polyethylene Exchange in Strictly Selected Patients with Infection after Total Knee Arthroplasty

( Whee Sung Son ),( Oog-jin Shon ),( Dong-chul Lee ),( Sang-jin Park ),( Han Seok Yang ) 대한슬관절학회 2017 대한슬관절학회지 Vol.29 No.3

Purpose: To assess the efficacy of open debridement and polyethylene exchange (ODPE) combined with proper antibiotic therapy in strictly selected patients with infection after total knee arthroplasty (TKA) and analyze factors associated with treatment failure. Materials and Methods: From January 2010 to January 2014, 25 cases that underwent ODPE under the diagnosis of infection within four weeks after TKA or acute hematogenous infection within five days of symptom onset were reviewed in this study. Results: Treatment was successful in 22 out of 25 cases (88.0%). Factors associated with failure were accompanying infection (periprosthetic infection in the ipsilateral foot, cervical parotid abscess, and masticator space abscess) and diagnosis of rheumatoid arthritis (RA) before TKA. Resistant bacteria did not entail a risk. On clinical results, the mean postoperative Lysholm score and Korean Knee score were 81.4 and 79.4, respectively, the knee range of motion was 115.4°±12.9°, and duration of hospitalization was 32.3±8.4 days. On radiographic results, 3.47±1.56 mm joint line elevation and a valgus change of 0.61°±2.35° in knee alignment were observed. Conclusions: ODPE combined with appropriate antibiotics therapy could be a useful treatment method for infection after TKA if the procedure is performed within a symptom duration of five days or less in the absence of accompanying infection in patients whose indication for TKA was not RA.

간 국한성 결절상 증식증의 신티그램 감별 진단

이성용,이명희,정수교,박용휘,손형선 대한핵의학회 1985 핵의학 분자영상 Vol.19 No.2

GPS를 이용한 교량 모니터링 시스템 연구

신익순(Kim Sung Kon),김성곤(Shin Ick Soon),손민철(Son Min chul),박희구(Park whee gu) 대한토목학회 2008 대한토목학회 학술대회 Vol.2008 No.10

The impact of COVID-19 on trauma patients and orthopedic trauma operations at a single focused training center for trauma in Korea

Choi Wonseok,Kim Hanju,Son Whee Sung,Sakong Seungyeob,Cho Jun-Min,Choi Nak-Jun,Noh Tae-Wook,Kim Namryeol,Cho Jae-Woo,Oh Jong-Keon 대한외상학회 2022 大韓外傷學會誌 Vol.35 No.3

Purpose: The objective of this study was to determine the effects of coronavirus disease 2019 (COVID-19) on the volume of trauma patients, the number of orthopedic trauma operations, and the severity of injuries. We also investigated the correlations between social distancing and these variables. Methods: This was a retrospective review of trauma patient cases at a single focused training center for trauma in Korea from January 2017 to April 2021. The COVID-19 group included patients treated from January 1 to April 30 in 2020 and 2021, and the control group included patients treated during the same months from 2017 to 2019. The volume of trauma patients according to the level of social distancing was evaluated among patients treated from August 2, 2020 to November 23, 2020. Results: The study included 3,032 patients who presented to the emergency department with traumatic injuries from January to April 2017 to 2021. The average number of patients was 646.7 and 546.0 in the control and COVID-19 groups, respectively. The percentage of patients injured in traffic accidents (TAs) decreased from 25.0% to 18.2% (P<0.0001). The proportions of in-car TAs and pedestrian TAs also decreased from 6.7% and 10.8% to 3.5% and 6.0%, respectively (P=0.0002 and P<0.0001). The percentage of bicycle TAs increased from 2.4% to 4.0% (P=0.0128). The proportion of patients with an Injury Severity Score above 15 and the mortality rate did not change significantly. As the level of social distancing increased, the number of trauma patients and the number of trauma injuries from TAs decreased. The number of orthopedic trauma operations also depended on the social distancing level. Conclusions: The number of trauma patients presenting to the emergency department decreased during the COVID-19 period. The volume of trauma patients and orthopedic trauma operations decreased as the social distance level increased.

관동맥이 완전폐쇄된 환자에서 측부순환과 99mTc - MIBI 심근 SPECT 소견 비교

손경환(Kyung Hwan Son),김권삼(Kown Sam Kim),이무열(Moo Yel Lee),이원호(Won Ho Lee),김덕윤(Deog Yoon Kim),강흥선(Heung Sun Kang),조정휘(Chung Whee Choe),김명식(Myung Sik Kim),송정상(Jung Sang Song),배종화(Jong Hwa Bae) 대한내과학회 1997 대한내과학회지 Vol.53 No.1

N/A Objectives: The role of coronary collateral circulation in protecting myocardium after the occlusion of a supplying artery has long been debated. Recent date show that the coronary collateral circulation may partially prevent ischemia and preserve myocardial contractile function. The purpose of this study was to evaluate the relation between the grades of collateral circulation and perfusion scores of 99mTc-Heart SPECT in patients with totally coronary occlusion. Methods: We studied 44 patients with totally coronary occlusion who had been hospitalized at Kyung Hee University hospital between October, 1989 and May, 1994, Patients were classified into two groups; Group 1: patients with angina pectoris (n=21), Group 2: patients with myocardial infarction (n=23). Angiographic collateral circulation was graded from 0 to 3: 0=none, 1=filling of side branch only, 2=partial filling of the epicardial segment, 3=complete filling of epicardial segment. The perfusion score of dipyridamole stress 99mTc-MIBI Heart SPCET was analyzed with angiographic findings. Resting and stress echocardiography were analyzed to identify left ventricular wall motion abnormalities. Results: 1) When LAD was totally occluded, there were hishevcrgree of collateral circulations from RCA in group 1 and group 2. When RCA was totally occluded, there was higherdesree of collateral circulation from LAD in group 1 and group 2. 2) The degree of collateral development was higher in group 1 than in group 2 (2.5±0.7 vs. 1.8±1.0, p<0.05). 3) In 99mTc-MIBI Heart SPECT, there was no significant difference of perfusion score at stress but perfusion score was significantly higher in group I than in group 2 at rest. 4) In 99mTc-MIBI Heart SPCET, there was no difference of perfusion score between totally coronary occlusion territories in group 1 and more than 50% coronary artery stenotic territories in group 1 and group 2. 5) In stress echocardiography, ten of the 13 patients showed normal LV wall motion at rest, but 9 of these 10 patients showed LV wall motion abnormalities at stress in group l. In group 2, all 10 patients showed LV wall motion abnormalities at rest and 3 of these patients showed more aggravation of LV wall motion abnormalities. Conclusion: Collateral circulation in angina patients can prevent myocardial ischemia and preserve myocardial function at rest, but not at exercise. Collateral circulation in patients with myocardial infarction cannot preserve myocardial function at rest. and exercise. Dipyridamole stress 99mTc-MIBI Heart SPECT is one of the indirect quantification methods to evaluate collateral development and coronary flow reserve.

Fabry disease exacerbates renal interstitial fibrosis after unilateral ureteral obstruction via impaired autophagy and enhanced apoptosis

( Sungjin Chung ),( Mina Son ),( Yura Chae ),( Songhee Oh ),( Eun Sil Koh ),( Yong Kyun Kim ),( Seok Joon Shin ),( Cheol Whee Park ),( Sung-chul Jung ),( Ho-shik Kim ) 대한신장학회 2021 Kidney Research and Clinical Practice Vol.40 No.2

Background: Fabry disease is a rare X-linked genetic lysosomal disorder caused by mutations in the GLA gene encoding alpha-galactosidase A. Despite some data showing that profibrotic and proinflammatory cytokines and oxidative stress could be involved in Fabry disease-related renal injury, the pathogenic link between metabolic derangement within cells and renal injury remains unclear. Methods: Renal fibrosis was triggered by unilateral ureteral obstruction (UUO) in mice with Fabry disease to investigate the pathogenic mechanism leading to fibrosis in diseased kidneys. Results: Compared to kidneys of wild-type mice, lamellar inclusion bodies were recognized in proximal tubules of mice with Fabry disease. Sirius red and trichrome staining revealed significantly increased fibrosis in all UUO kidneys, though it was more prominent in obstructed Fabry kidneys. Renal messenger RNA levels of inflammatory cytokines and profibrotic factors were increased in all UUO kidneys compared to sham-operated kidneys but were not significantly different between UUO control and UUO Fabry mice. Protein levels of Nox2, Nox4, NQO1, catalase, SOD1, SOD2, and Nrf2 were not significantly different between UUO control and UUO Fabry kidneys, while the protein contents of LC3-II and LC3-I and expression of Beclin1 were significantly decreased in UUO kidneys of Fabry disease mouse models compared with wild-type mice. Notably, TUNEL-positive cells were elevated in obstructed kidneys of Fabry disease mice compared to wild-type control and UUO mice. Conclusion: These findings suggest that impaired autophagy and enhanced apoptosis are probable mechanisms involved in enhanced renal fibrosis under the stimulus of UUO in Fabry disease.

일리자로브를 이용한 슬관절 굴곡 및 외반 변형의 점진적 교정

박철현(Chul Hyun Park),손휘승(Whee Sung Son),손욱진(Oog-Jin Shon) 대한정형외과학회 2016 대한정형외과학회지 Vol.51 No.6

슬관절 굴곡 변형 및 구축에 대한 치료에는 연부조직 술기와 골 조직 술기를 포함한 다양한 수술적 방법들이 사용되고 있다. 하지만 급격한 교정으로 인한 신경이나 혈관의 손상 및 피부의 괴사 등의 합병증들이 보고되고 있다. 저자들은 화농성 관절염의 합병증으로 발생한 슬관절 굴곡 및 외반 변형 유합으로 보행 장해를 주소로 내원한 24세 남자 환자에서 상과부 절골술 후 일리자로브를 이용한 점진적 교정을 통해 좋은 결과를 얻어 이를 보고하고자 한다. Various surgical methods including soft tissue procedures and bone procedures are commonly used to treat knee flexion and contracture deformity. However, several complications such as, neurovascular injury and skin necrosis were reported because of rapid correction. We aim to report good results from gradual correction using Ilizarov following supracondylar osteotomy in a 24-year-old man suffering from fused knee flexion and valgus deformity, a complication developed by septic arthritis.

Dynamic Mechanical Analysis of 3D Printed Implant in Bone Defected Animal Model

Yong-Hoon Jeong(정용훈),Tae-Gon Jung(정태곤),Kwan-Su Kang(강관수),Whee-Sung Son(손휘승) 한국표면공학회 2021 한국표면공학회 학술발표회 초록집 Vol.2021 No.12

재발성 화농성 관절염에 대한 치료로서의 2단계 인공관절 치환술

손욱진(Oog Jin Sohn),이동철(Dong Chul Lee),이성준(Sung Jun Lee),문정재(Jeong Jae Moon),손휘승(Whee Sung Son) 대한정형외과학회 2014 대한정형외과학회지 Vol.49 No.2

목적: 퇴행성 관절염이 동반된 재발하는 화농성 슬관절염 환자에서 인공관절 치환술의 유용성을 평가하고자 하였다. 대상 및 방법: 2005년 1월부터 2012년 4월까지 최소 1년 이상의 추시된 관절염을 동반한 재발한 화농성 슬관절염 환자 중 2단계 인공관절 치환술을 시행한 22예를 대상으로 하였다. 임상적 평가는 슬관절 점수, 기능적 점수, International Knee Documentation Committee (IKDC) 평가를 이용하였으며, 방사선 소견, 배양 균주, 당뇨병 유무, 인공관절 치환술까지 소요된 기간 등에 따른 결과를 분석하였다. 결과: 최종 추시 시 슬관절 운동 범위는 평균 115o였으며, 수술 후 슬관절 점수는 평균 81.0점, 슬관절 기능 점수는 평균 73.2점이었 으며, IKDC 주관적 만족도 평가에서는 normal 15예, nearly normal 7예로 조사되었다. 당뇨병을 가진 환자군이나 배양 균주가 검출 된 환자군에서 유의한 차이는 없었다. 최종 추시 시 슬관절의 감염이 재발한 예는 없었다. 결론: 퇴행성 관절염이 동반된 재발성 화농성 슬관절염 환자에서 2단계 인공관절 치환술은 만족할 만한 결과를 보여, 치료방법의 하 나로서 선택적으로 사용할 수 있을 것으로 생각한다. Purpose: The purpose of this study is to evaluate the usefulness of a two-stage approach to primary knee arthroplasty with recurrent septic arthritis. Materials and Methods: We studied 22 patients with recurrent septic arthritis, and we observed them for more than one year of follow-up survey from January 2005 to April 2012 at Yeungnam University Medical Center. The clinical assessment was performed following Knee Society knee score, Knee Society function score, and International Knee Documentation Committee Score (IKDC) subjective assessment. In addition, we analyzed the causative organisms, significant medical comorbidities (diabetes mellitus), period up to primary knee arthroplasty, and radiologic assessment with reference to disease prognosis. Results: The average range of postoperative knee motion showed a good result, with an average of 115o. Knee Society knee score improved from 23.5 to 81.0, and Knee Society function score also increased from 22.5 to 73.2. Subjective assessment by IKDC was divided into 15 normal patients and 7 nearly normal patients. No significant difference was observed between patients with causative organisms and those with diabetes mellitus. In the final follow-up survey, recurrence of infection was not reported. Conclusion: A two-stage approach to primary knee arthroplasty with recurrent septic arthritis is a useful method, because it showed good clinical and radiologic results and favorable subjective assessment.