http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Predictions of PD-L1 Expression Based on CT Imaging Features in Lung Squamous Cell Carcinoma
Seong Hee Yeo,Hyun Jung Yoon,Injoong Kim,Yeo Jin Kim,Young Lee,Yoon Ki Cha,So Hyeon Bak 대한영상의학회 2024 대한영상의학회지 Vol.85 No.2
Purpose To develop models to predict programmed death ligand 1 (PD-L1) expression in pulmonary squamous cell carcinoma (SCC) using CT. Materials and Methods A total of 97 patients diagnosed with SCC who underwent PD-L1 expression assay were included in this study. We performed a CT analysis of the tumors using pretreatment CT images. Multiple logistic regression models were constructed to predict PD-L1 positivity in the total patient group and in the 40 advanced-stage (≥ stage IIIB) patients. The area under the receiver operating characteristic curve (AUC) was calculated for each model. Results For the total patient group, the AUC of the ‘total significant features model’ (tumor stage, tumor size, pleural nodularity, and lung metastasis) was 0.652, and that of the ‘selected feature model’ (pleural nodularity) was 0.556. For advanced-stage patients, the AUC of the ‘selected feature model’ (tumor size, pleural nodularity, pulmonary oligometastases, and absence of interstitial lung disease) was 0.897. Among these factors, pleural nodularity and pulmonary oligometastases had the highest odds ratios (8.78 and 16.35, respectively). Conclusion Our model could predict PD-L1 expression in patients with lung SCC, and pleural nodularity and pulmonary oligometastases were notable predictive CT features of PD-L1.
위 말트(Mucosa-Associated Lymphoid Tissue) 림프종의 치료 후 장기성적: 단일기관 연구
Seong Hyun Koh,Seung Hyun Yeo,Moo In Park,Kyoungwon Jung,Sung Eun Kim,Won Moon,Seun Ja Park 대한상부위장관ㆍ헬리코박터학회 2024 Korean Journal of Helicobacter Upper Gastrointesti Vol.24 No.1
Objectives: Few studies have reported long-term follow-up after treatment of gastric mucosaassociated lymphoid tissue (MALT) lymphoma. In this single-center study, we investigated longterm treatment outcomes in patients diagnosed with gastric MALT lymphoma. Methods: The study included 80 patients diagnosed with gastric MALT lymphoma, who were followed up at a single center between January 2005 and December 2019 after Helicobacter pylori eradication therapy, radiotherapy, or chemotherapy. We evaluated complete remission, improvement, or recurrence of the lesion. Follow-up over >60 months was classified as long-term follow-up, and the progression-free survival rate was recorded. Results: Following H. pylori eradication treatment, complete remission occurred in 85.9% (55/64) of H. pylori-positive and 50.0% (3/6) of H. pylorinegative patients. All patients with gastric MALT lymphoma who did not respond to H. pylori eradication therapy (100.0% [6/6]) achieved complete remission following administration of local radiotherapy. We observed no deaths on long-term follow-up (>60 months), and the progression-free survival was 101 months. Conclusions: In this study, patients with gastric MALT lymphoma showed excellent survival rates, progression-free survival, and prognosis on long-term follow-up. Prospective studies are warranted to determine the long-term prognosis of gastric MALT lymphoma after treatment.
Nutritional status assessed by bioimpedance analysis in hemodialysis patients
( Eung Hyun Lee ),( Seong Yup Yeo ),( Chae Rim Kim ),( Ki Hyun Park ),( Jung-ho Shin ),( Jin Ho Hwang ),( Su Hyun Kim ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Protein-energy wasting is common in patients with end-stage renal disease (ESRD), and it is known as an independent risk factor for major adverse events such as hospitalization and death. Recently, bioimpedance analysis (BIA) has been widely used as noninvasive method to estimate body composition and nutritional status. In this study, we retrospectively investigated whether nutritional markers measured by BIA can predict outcomesin ESRD patients with hemodialysis. Methods: ESRD patients who had been treated with outpatient hemodialysis were recruited between October 2011 and April 2015. Using BIA, body cell mass (BCM) and phase angle (PA) were obtained every 6 months. The correlation between BIA results and clinical data were analyzed. We evaluated the rates of cardiovascular events, infection and all-cause mortality according to BIA results. Results: There were 71 (55.5%) men and 57 (44.5%) women, and the mean age was 65 ± 13 years. The baseline BCM and PA were 47.4 [42.6, 53.0]% and 4.5 [3.8, 5.3] °, respectively. The BCM was negatively correlated with age, Charlson comorbidity index and body mass index (r=-0.2, -0.2 and -0.5, p=0.034, 0.027 and p<0.001), but that was positively related with serum albumin and creatinine (r=0.2 and 0.3, p=0.065 and 0.001). On the other hand, the PA had a negative correlation with age, Charlson comorbidity index and serum total carbon dioxide (r=-0.4, -0.4 and -0.3, p<0.001, p <0.001 and p 0.004), but positive with serum albumin and creatinine (r=0.4 and 0.6, both p<0.001). In this study, the BCM could not predict the adverse outcomes including cardiovascular events, infection and all-cause mortality. The PA also did not correlate with cardiovascular events. However, the PA was significantly associated with infection and mortality, and it was independent of age, sex and Charlson comorbidity index (HR 0.62 and 0.33, p=0.050 and 0.017). Conclusions: Nutritional status can be assessed using BIA and those provide substantial information in ESRD patients with hemodialysis. Especially, a low level of PA may correlate with an increased risk of infection, moreover it may predict poor prognosis.
바이오매스 합성가스를 이용한 혼소식 디젤엔진 발전기의 적용성 평가
윤여성 ( Yoon Yeo Seong ),서도현 ( Seo Do Hyun ),강구 ( Kang Ku ),최선화 ( Choi Sun Hwa ),홍성구 ( Hong Seong Gu ) 한국농공학회 2017 한국농공학회논문집 Vol.59 No.1
Biomass gasification produces syngas or producer gas as low calorific fuel gas that can be used as a fuel for combustion or prime movers as well as chemical synthesis. Internal combustion engines are readily available with lower costs and easily used for producing distributed power using biomass syngas. In this study, a dual fuel diesel engine was used to evaluate its performance when biomass syngas is used for fuel. The engine was originally developed for biogas application with a diesel engine with a 2,607 cc displacement. Both diesel fuel and syngas consumptions were observed at the different load conditions. The results indicate that the dual fuel engine showed a reasonably good performance and up to 63 % of diesel fuel saving.
Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis
Yeo, Hye Ju,Lee, Soo Yong,Ahn, Eunyoung,Kim, Eun Jung,Rhu, Dae Gon,Choi, Kyoung Un,Lee, Seung Eun,Cho, Woo Hyun,Jeon, Doosoo,Kim, Yun Seong The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.75 No.5
This report describes a rare case of a patient with splenic tuberculosis (TB) who developed spontaneous splenic rupture after 10 weeks of antituberculous chemotherapy. The patient responded well to the antituberculous regimen prior to the spontaneous splenic rupture. We considered a paradoxical reaction as a cause of the splenic rupture. The patient underwent splenectomy and continuously received initial antituberculous drugs without change. To the best of our knowledge, this is the first report of spontaneous splenic rupture as a paradoxical reaction to antituberculous chemotherapy in an immunocompetent host with splenic TB.