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      • KCI등재

        Prediction of Retained Austenite Fraction in Quenching-and-Partitioning (Q&P) Steels Using the Gibbs Energy Balance Approach

        Seong Hoon Kim,Ji Hoon Kim,Jae Hoon Lee,Dong‑Woo Suh,Jae Sang Lee 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

        Prediction of retained austenite fraction is quite important in designing advanced high strength steels since retained austeniteis the source of transformation-induced plasticity. The present study investigates the phase constitution of a medium-carbonQ&P steel by comparing various approaches to the transformation stasis of bainitic ferrite and applying them to the partitioningprocess. Among them, the modified GEB approach gave the best agreement with the experimental observation, includingthe effects of heat-treatment condition and chemical composition on phase constitution. This indicates phase transformationduring partitioning can be effectively described by the physics of Gibbs energy balance approach.

      • KCI등재

        혈액암환자에서 조혈모세포 이식 후 따르는 헤르페스 바이러스 감영 양상

        이호섭,탁희상,신성훈,김양수,남성진,김혜수,박진희,정수현,김성빈,김예나 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

        배경 : 헤르페스바이러스과에는 단순포진 바이러스(HERPES SIMPLEX VIRUS, HSV), 수두대상포진 바이러스 (VARICELLA-ZOSTER VIRUS, VZV), 엡스타인-바 바이러스 (EPSTEIN-BARR VIRUS, EBV), 그리고 거대세포 바이러스 (CYTOMEGALOVIRUS, CMV) 등이 있다. 헤르페스바이러스 감염은 혈액암환자에서 조혈모세포 이식 환자에서 전파 (dissemination), 이차감염, 세균 중복 감염의 심각한 합병증을 일으킬 수 있다. 하지만 항암약물치료를 받는 림파종 환자에서 항 바이러스 약제의 사용 용량과 기간에 대한 concensus는 없다. 헤르페스바이러스 감염에 대한 발생율과 위험인자를 후향성으로 분석하였다. 방법 : 고신대학교 복음 병원에서 1995년 6월부터 2009 년 2월 사이에 새롭게 진단되어 조혈모세포 이식을 받은 전체 58명의 환자들이 후향적으로 현 연구에 등록했다. 헤르페스 바이러스 감염은 임상적 진단, 혈청학적 검사 또는 병리학적 진단에 기초하여 확진한다. 환자들의 특성은 다음과 같다: 평균 연령은 44세 (범위 19-62세)였고 남녀비는 30:28이었다. 등록된 질환은 백혈병 (n=9, 15.5%), 림프종 (n=30, 51.7%), 다발성 골수종 (n=12, 20.7%), 재생불량성 빈혈 (n=6, 10.3%) 그리고 골수이형성증후군 (n=1, 1.7%)이 포함되었다. 결과는 chi-squre test나 independent samples T test를 사용하여 분석되었다. Multivariate analysises에 대해 logistic regression test를 사용하였다. 결과 : 15명의 환자들 (25.9%)에서 조혈모세포 이식후 헤르페스 바이러스 감염이 발생하였다. 조혈모세포 이식 5년간 누적 발생율은 53.9%였다. Univariate analyses에서 헤르페스 바이러스 감염에 대한 유의한 위험 인자는 없었다. 하지만 조혈모세포 이식후 생존 기간(40.18 ± 30.14 months vs 20.06 ± 26.67 months, p=0.018)은 헤르페스 바이러스 감염의 낮은 발병율과 유의한 관련성이 있었다. 이식 편대 숙주질환 (GVHD)의 존재 (37.5% in developed GVHD vs 0% in no GVHD, p=0.200), 동종조혈 모세포 이식에서 면역억제요법의 기간 (15.98 ± 14.02 months vs 6.78 ± 3.67 months, p = 0.374)은 헤르페스 바이러스 감염에 대한 위험인자가 아니었다. 결론 : 조혈모세포 이식 후 생존 기간은 어사이클로비어 예방을 받은 혈액암 환자에서 헤르페스 바이러스 감염의 낮은 발병율과 연관성이 있는 것으로 보인다. 저용량의 어사이클로비어 예방은 헤르페스 바이러스 감염의 고위험군인 조혈모세포 이식을 받은 혈액암 환자에 필요하리라 생각된다. Background : Herpesviridae family includes herpes simplex virus, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus, etc. Herpesviridae viral infection (HVI) can lead to serious complications including dissemination, secondary infection, bacterial superinfection in patients with hematologic malignancy following hematopoietic stem cell transplantation (HSCT). But there was no consensus on the dose and duration of antiviral agents prophylaxis in patients undergoing chemotherapy. We retrospectively analyzed the incidence and the risk factors for HVI. Method : A total of 58 patients who newly diagnosed and received HSCT with prophylaxis of acyclovir at the Kosin University Gospel Hospital, Busan, Korea between June 1995 and February 2009 were enrolled retrospectively in the current study. HVI was confirmed based on clinical diagnosis, serologic test or pathologic diagnosis. The characteristics of the patients were as follows: the median age was 44 years (range 19-62 years) with a female-to-male ratio of 30:28. The enrolled diseases included leukemia (n=9, 15.5%), lymphoma (n=30, 51.7%), multiple myeloma (n=12, 20.7%), aplastic anemia (n=6, 10.3%) and myelodysplastic syndrome (n=1, 1.7%). The results were analyzed using a chi-square test and independent samples T test. For the multivariate analysis, we used logistic regression test. Results : Fifteen patients (25.9%) developed HVI after HSCT. The cumulative incidence of HVI was 53.8% at 5 years after HSCT. In univariate analysis, there was no significant risk factor for HVI. The presence of graft-versus-host disease (GVHD) (37.5% in developed GVHD vs. 0% in no GVHD, p=0.200), duration of immunosuppressive therapy (IST) in allo-SCT (15.98 ± 14.02 months vs. 6.78 ± 3.67 months, p = 0.374) were not risk factors for HVI. Conclusion : The incidence of HVI was similar to that in historical other studies. There was no risk factor associated with development of HVI. Most of the HVI occurred within the first 24 months after transplantation. So long term use of antiviral prophylaxis may be needed to prevention of HVI after HSCT.

      • KCI등재

        격투스포츠 선수의 스포츠맨십 분석

        박태훈(Park Tae-Hoon),유기성(Yoo Ki-Seong),유원용(Ryu Won-Yong),김영욱(Kim Young-Wook),이양구(Lee Yang-Gu),공창빈(Kong Chang-Bin),이상호(Lee Sang-Ho),김태영(Kim Tae-Young) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.3

        This research examines whether difference that is some in inclination of combat sports player's sportsmanship is, and accordingly is purposeful to clear relation. combat sports (fencing, Taekwondo, boxing, induction, wrestling, wrestling) player who research target is having player life in middle·high·an university 399 people be . Used Korean-made measure (KMSOS) that Seong-changhun (2003) verifies changing based on Vallerand MSOS by a tool to measure sportsmanship of players. Data processing used SPSS 12.0 programs. Did reliability analysis that use Cronbach'a coefficient to verify believability of an irradiation tool, Difference of sportsmanship used t-test, one-way ANOVA. In this research, drew following conclusion. First, man appeared higher level than woman in wave and human desire, decision respect, and woman appeared higher level than man in victory or defeat excessive fondness. Second, exercise immersion, decision respect, victory or defeat excessive fondness appeared level that minority is taller than majority. Third, in exercise immersion high school player decision respect appear, and tendency of level that middle school playing the first stone is high in victory or defeat excessive fondness appeared. Fourth, striking radical type of player appeared higher level than Geuraepeulring type of player in companion respect factor. Fifth, player less than exercise career 4 years appeared higher level than player less than 7 years and player more than 7 years for victory or defeat excessive fondness factor. Sixth, Taekwondo for best and companion respect factor, high level appeared to boxing item players.

      • 한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

        최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

      • 人間으로서의 존엄과 價値 : 憲法 第8條의 解釋을 中心으로

        金成勳 제주한라대학 1975 論文集 Vol.1 No.-

        Ⅰ. Preface The dignity and value as human beings will be studied, centered on the explation of Article 8 of the constitution of Korea, and on the relationship with Article 32, The Article 8 and 32 are as fallows: Article 8 : All citizens shall have the dignity and value as human beirgs, and it shall be the duty of the state to guarantee fundamental rghts of the people to the utmost. Article 32 : ① Liberties and rights of the citizens shll not be ignored for the reasons that they are not enumerated in the constitution. ② All liberties and rights of citizens may be restricted by law only in casesdem and necessary for the maintenance of order and public welfare. In case of such restriction, the essential substances of liberties and rights shall not be infringed. Ⅱ. The history and development of the human dignity rights. Modern democracy has its own value on the individualism and liberalism principled by human dignity and value. And owing to the emergence of totalitarianism and communism to deny the dignity and value of human beings after the World War Ⅰ, post World War Ⅱ every nation has come to regulate them in its constitution. Ⅲ. Contents and significance The dignity of signifies the contents of personality considered as its essence, and its value signifies an absolute estimate of man. The rights of dignity is true even of foreigners or those who lose citizenships but not of a corporate body. As the dignity and value of man have this two fold aspect of being spiritual and economic, the value security of them reguires that of the individual freedom and rights to live a human life. Ⅳ. The legal offect of human dignity rights As the security of human dignity and value -that of all citizens fundamental rights-is the rightful duty of government, all powers of a nation should be centered on the defence of human dignity and value, which is also thought to be applied indirectly to private laws. Ⅴ. The legal character of Article 8 of the Constitution The Article 8 is a basic norm which has regulated the thought of respect of fundamental rights and placed the superiority of individual before government as far as the fundamental rights are concerned. Ⅵ. The restrictions of human dignity righis As the human dignity and value are essential contents of fundamental rights, they may not be restricted thanks to Article 32, clause 2.

      • 류마티스성 승모판 협착증의 치료를 위한 경피적 승모판 성형술의 치료성적

        김성은,조흥근,박성훈,박시훈 梨花女子大學校 醫科大學 醫科學硏究所 1999 EMJ (Ewha medical journal) Vol.22 No.4

        연구목적 : 류마티스성 승모판 협착증에 대한 유용한 치료법인 경피적 승모판 성형술의 본원의 단기 치료 성적을 알아보고자 하였다. 방법: 1993년 10월에서 1999년 4월까지의 이대목동병원에 내원한 류마티스성 승모판 협착증 환자 21명에서 투시조명 하에 경피적 승모판 성형술을 시행하였다. 시술전에 경흥부심초음파와 경식도초음파가 시행되었고, 시술후에는 경흉부초음파를 사용하여 혈역학적, 임상학적 변화를 비교하였다. 연구대상의 거의 모두가 NYHA class Ⅱ에 속했고, 5명이 심방세동을 가지고 있었으며, 모두 심초음파점수가 8이하였다. 좌심방에 혈전이 있는 경우로 혈전을 용해시킨 후 시술한 경우가 2예였다. 결과 : 경피적 승모판 성형술 이후의 평균 승모판구면적은 시술전의 1.16±0.36㎠에서 2.06±0.33㎠로 증가되었다. 경승모판 이완기 평균 압력차는 시술전 11.60±5.54mmHg에서 시술 후 4.93±2.53mmHg(p<0.001). 좌심방 크기는 46.41±14.66mm에서 42.03±15.01mm로(p=0.042), 그리고 심박출량은 4.21±1.25L/min에서 6.88±9.57L/min로(p<0.0001) 의미있는 호전을 보였다. 3도 이상의 심한 승모관폐쇄부전이나 심각한 시술후 합병증은 없었다. 결론 : 본원에서 약 6년간 시행된 경피적 승모판 성형술는 그 사례가 적고 시술전 예상되는 난이도 면에서 특이한 것은 없었지만, 시술후 합병증이 거의 발견되지 않았으며 혈역학적 측정상에서도 성공적인 시술을 보여주었다. 승모판구면적에 따른 시술후 단기내 호전의 정도는 거의 예측할 수 없었으나, 심초음파점수는 모두가 8점이하로 높은 성공율의 조건을 제공하였다. Objective : Percutaneous mitral valvuloplasty(PMV) became a treatment modality or mitral stenosis because of its low morbidity, short hospital stay, and low cost. We reviewed clinical and hemodynamic results after PMV for the patients with mitral stenosis in Ewha Womans University Mokdong hospital. Methods : We compared the results of echocardiographic, hemodynamic, and clinical parameters before and after PMV. PMV was performed under fluoroscopic guidance in 21 patients(M:4, F:17, mean age 43±12 years) with mitral stenosis from October 1993 to April 1999. Transesophageal echocardiography(TEE) and Transthoracic echocardiography(TTE) were performed for the evaluation of mitral valve, chamber size, and the presence of left atrial thrombus before procedures. TIE was also used for follow-up evaluation. On presentation, all patients showed at least NYHA class Ⅱ. Five patients had atrial fibrillation. Two patients with thrombus in the left atrium were included to study group after thrombolytic treatment with coumadin. Echo-score of our patients was not greater than 8. Results : Mean mitral valve area(MVA) by 2 dimensional or Doppler echocardiography was increased from 1.16±0.36㎠ before PMV to 2.06±0.33㎠ after PMV. There were marked improvements in transmitral gradients(11.60±5.54mmHg before PMV vs 4.93±2.53mmHg after PMV, p<0.001), left atrial dimension(46.41±14.66mm vs 42.03±15.01mm, p=0.042), and cardiac output(4.21±1.25L/min vs 6.88±9.57L/min, p<0.0001) following PMV, Severe(≥GⅢ) mitral insufficiency or severe postprocedural complications were not noted. This suggested that all procedure was successful. Conclusion : The Procedural success rate of PMV in Ewha Womans University Mokdong hospital was 100%. Low echo score of our patients might explain this high procedural success rate. Long-term-follow-up is warranted in the near future.

      • 醫藥品의 安定性에 關한 硏究 (第3報) : Sulpyrin 水溶液의 安定性에 關하여 The Stability of Sulpyrin in Aqueous Solution

        金鍾秀,金壽億,徐成勳 慶熙大學校 1983 論文集 Vol.12 No.-

        The pharmacokinetic study of solution was conducted to determine the stability of sulpyrin. The powder was added with diluents and stored under three different conditions to determine the humiditification weight and degradation rate. The solution of sulpyrin indicated first order reaction and t_90 was 82 days at 25℃. When the powder was stored under the three different conditions, the avicel mixture showed the highest humiditification weight, while the only sulpyrin showed the highest degradation rate under the relative humidity of 75% and 92% followed by the avicel mixture. The starch and lactose mixture showed the lowest similar humiditification weight and degradation rate. Therefore, it seems that the stability of the main ingredient will be greatly influenced by the diluents.

      • 평판구조물의 동적해석을 위한 유한요소의 개선

        김선훈,유승운 永同大學校 1999 硏究論叢 Vol.5 No.1

        본 논문에서는 평판구조물의 동적해석에서 우수한 결과를 보여주는 개선된 유한요소를 제시하였다. 이 요소는 Mindlin평판이론에 의하여 수식화되었으며, Heterosis평판요소의 변위장에 2개의 비적합변위형을 추가함으로서 유도되었다. 본 논문에서 제시한 평판유한요소는 다른 요소들에 비해 신속한 수렴성을 보였으며, 아주 얇은 평 판문제에서도 요소의 형상에 관계없이 전단구속현상을 극복하였다. 또한 이 요소는 평판구조물의 동적해석에서도 신뢰할 만한 결과를 보여줌을 알 수 있었다. An improved finite element for dynamic analysis of plate structures is suggested in this paper. This element is based upon Mindlin plate concept. The displacement field of this element is also formulated by adding two non-conforming modes to rotational displacement components of a heterosis plate element. It is shown that the results obtained by the proposed element converged to analytical solutions very rapidly through numerical studies for various benchmark problems, and overcome the shear locking problem completely in very thin plate situation even for distorted meshes. It is also noted that the element is applicable to the dynamic analysis of plate structures.

      • 부산 신평·장림공단지역의 대기오염물질 배출 특성

        김상헌,정장표,김영태,조성훈 慶星大學校 環境問題硏究所 1995 環境硏報 Vol.5 No.1

        Industrial growth and urban gravitation of the population etc. have seriously deteriorated the air quality which has adverse effect on human health and property, and the situation is more serious in industrial complex as well. Therefore, it is necessary to examine the pollutants emissions inventory to establish proper and comprehensive strategies for the reduction of pollutant levels. This study is aimed at investigating the characteristics of the pollutant emissions in the vicinity of Sinpyeung·Jangrim industrial complex in Pusan. The emission quantities of air pollutants were estimated by the grid(1㎞x1㎞), the source classification, and the time on the basis of the type and the amount per month of the fuel. The important results from this study were as followings: The average emission quantity(rate) of SO₂, TSP, NOx, CO and HC showed 1926.74 ton/yr(61.09 g/sec), 367.83 ton/yr(11.66 g/sec), 1440.64 ton/yr(45.68 g/sec), 4698.33 ton/yr(148.98 g/sec) and 447.15 ton/yr(14.18 g/sec), respectively. In case of SO₂and TSP, the emission quantities were majorly contributed by stationary source(point source and area source) whose contribution percentages were calculated as 65.8%, 30.6%. On the other hand, emission quantities of NOx, CO and HC were highly contributed by mobil source(line source) whose contribution percentages were calculated as 59.3%, 84.2% and 88.6%.

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