전방 불안정성 견관절에서 이두박근의 근전도 활동성

김승호,하권익,김현숙,김선우,박종혁,김영민 대한견.주관절학회 2000 大韓肩.주關節學會誌 Vol.3 No.2

子宮內膜搔爬術 21例의 鍼麻醉效果에 대한 臨床的 硏究

金在圭,金相佑,李宜暻,金建植,金相佑,南相永 경희대학교 1997 慶熙醫學 Vol.13 No.1

Proteomic Approach to Analyzing Flooding Stress in Soybean (Glycine max(L.) Merr.)

Kim,Tae-Seon,Cho,Seong-Woo,Lee,Jae-Eun,Kim,Yook-Han,Cho,Kun,Choi,Jong-Soon,Chung,Keun-Yook,Song,Beom-Heon,Jong,Seung-Keun,Kim,Hong-Sig,Woo,Sun-Hee 한국작물학회 2005 한국작물학회 학술발표대회 논문집 Vol.2005 No.-

Multi‑tissue lipotoxicity caused by high‑fat diet feeding is attenuated by the supplementation of Korean red ginseng in mice

Seon‑A Jang,Seung Namkoong,이성률,Jin Woo Lee,Yuna Park,Gyeongseop So,Sung Hyeok Kim,Mi‑Ja Kim,Ki‑Hyo Jang,Alberto P. Avolio,Sumudu V. S. Gangoda,Hyun Jung Koo,Myung Kyum Kim,Se Chan Kang,Eun‑Hwa Sohn 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.1

Background Excessive intake of fat, one of the causes of obesity, is associated with low-grade infammation in various susceptible organs and eventually causes tissue toxicity. This study examines the multifaceted suppressive efects of Korean red ginseng extract (KRG) on high-fat diet (HFD)-induced lipotoxicity and infammatory responses in the aorta, liver, and brain. Methods Male C57BL/6 mice were fed HFD with or without KRG for 12 weeks. The improvement efect in KRG on lipotoxicity and infammatory potential was determined in the blood and the aorta, liver, and brain tissues. Results KRG signifcantly inhibited 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by >20% in vitro. KRG supplementation suppressed HFD-associated body weight gain, lipid profle changes, and excessive fat deposition in the liver and increased leptin, insulin, and ALT levels in the blood. Infammatory markers in the aorta, liver, and brain were also signifcantly reduced by KRG treatment. In microvascular endothelial cells, the 15% cyclic stretch-mediated upregulation of ICAM-1 and vascular cell adhesion protein-1 (VCAM-1) expression was signifcantly attenuated in the presence of KRG. Conclusion KRG supplementation attenuates HFD-mediated body weight gain, lipid profle changes, and multi-tissue infammatory responses.

핵전달 방법에 의한 Aspergillus 속 종간잡종 형성에 관하여

김선우,이숙영,양영기 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

핵전달 방법에 의해 A. nidulans FGSC 514와 A. niger의 종간잡종을 얻었고 그들 특성을 관찰한 결과는 다음과 같다. 1. A. nidulans FGSC 514의 원형질체 형성은 삼투안정제인 0.6M KCI과 0.5% Novozym 234를 2시간 처리하여 2x10^7 원형질체를 얻었다. 2. A. niger의 원형질체 형성은 삼투안정제로 0.6M KCI, 0.5% Novozym 234, 0.3% β-glucuronidase와 0.4% BSA를 2시간 처리하여 6x10^7 원형질체를 얻었다. 3. A. niger의핵을 추출하여 A. nidulans FGSC 514 원형질체를 형질전환시켜 3.5%의 형질전환률을 얻었다. 4. 형질전환체의 섬유소 분해효소 활성은 CMCase, avicelase와 pectinase에서 대체적으로 증가하였고 β-glucosidase에서는 모균주보다 약간 감소하는 경향을 보였다. 5. 형질전환체의 건조균체량은 모균주에 비해 대체적으로 높게 나타났고 배양 10시간부터 25시간까지 급격한 증가를 보였으나 40시간 후에는 거의 증가하지 않았다. 6. 형질전환체의 DNA 함량은 1.5∼2.23㎍/10^7pts로 모균주에 비해 약 1.4∼2.0배 증가하였다. 7. 세포외 수용성 단백질은 전기영동 양상은 형질전환체들은 유사하나 모균주의 A. nidulans FGSC 514와 A. niger과는 양상이 다른 중간형태를 나타내었다. The properties of interspecific hybrids obtained by nuclear transfer method between A. nidulans FGSC 514 and A. niger wild type were analyzed by enzyme activity, protein determination, dry weight, DNA content, and total solube protein. The protoplast formation from A. niger was 6x10^7 pts with the treatment of 0.6M KCI, osmotic stabilizer, 0.5% novozym 234, 0.3% β-glucuronidase and 0.4% BSA for 2 hrs. When the isolated nuclei of A. niger wild type were transformed the protoplasts of A. nidulans FGSC 514, transformation frequency was 3.5%. It was found that the enzyme activities in degradation of cellulose and polysaccharide were increased in CMCase, avicelas and pectinase but decreased in β-glucosidase. The strains in which enzyme acttivity in general had a tendency of increasing apecific activity and protein content. The dry weight of transformants were increased more than the parent and increased fast from 10 to 25 hrs. The DNA content of transformants were 1.5∼2.23㎍ and 1.42∼2.04 times more than that of both A. nidulans FGSC 514 and A. niger wild type. Electrophoretic patterns of extracellular solube protein were different between parental and transformant strains.

박실지의 대형수생식물상과 그 분포에 관한 연구

김인택,정선우,이다정 7개 국립대학교 환경연구논문집 공동발행 위원회 2005 공업기술연구 Vol.5 No.-

The flora(macro-hydrophyte) Vegetation of Baksil reservoir and surrounding area was investigated from March, 2005 to October, 2005. The Macro-hydrophyte of this area consist of 33 taxa : 3 variety, 30 species, 30 genera and 22 family. The Maro-hydrophyte of this area consist of Emergent Plants : 16 species, 14 genera, 11 family, Submerged plants : 4 species, 4 genera, 3 family, Free-floating Plants : 3 species, 3 genera, 2 family, Floating leaved Plants : 2 species, 2 genera, 2 family, Hygrophytes Plants : 5species, 5 genera, 4 family. The communites of Jeongyang lake : Miscanthus Sacchariflorus community, Zizania latifolia community, Phragmites communis community, Tyhpa orientalis community and Trapa japonica community. The life form spectrum : Emergent Plants 49%, Submerged Plants 12%, Free-floating Plants 9%, Floating leaved plants 6%, Hygrophytes plants 15%.

응력경로에 따른 섬진강 모래의 탄성특성

김문규,남선우,정현철 동아대학교 건설기술연구소 1997 硏究報告 Vol.21 No.2

Usually, Many Engineers have used predicting the settlement and displacement using linear elastic modulus(E_(50) calculated by the conventional triaxial test results. But it is results are very diffemt from those of field, which follows deffent stress path and nonlinear behaviour. Therefore, to investigate the dependence of stress path with the variation of confining pressure and relative density on Sum-Jin River sand, local strain triaxial tests are preformed. It is showed as follows ; For the same stress path condition, the stiffness increased with increasing confining pressure and relative density, especially it is more affected by confining pressure. From the relations between Young's modulus and axial strain showed all nonlinear-elastic behaviour and independent on testing conditions, such as, confining pressure, relative density and stress path, etc. The mount of stiffness at very small strain range showed very high value and linear elastic behaviour. And compression results are rather overestimated than that of extention.

정상인과 혈액질환 환자에서의 혈소판 평균용적치에 관한 연구

김학현,구선회,박종우 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

Molphologic study of platelet have been done by many authors for the past years, they investigated that the heterogeneity of platelet size was shown even in normal person and various hematologic disorder. In the past the platelet size was not utilized in clinical medicine because of its technical difficulties of measuring. Recently, and automated blood cell counter, Coulter counter Model Splus Ⅱ®, was introduced and platelet size could be easily gained, which expressed by mean platelet volume(MPV). Therefore, this study was planned to evaluated the clinical significance of MPV in health person and various hematologic disease. The following results were obtained: 1. In healthy person, MPV was decreased along with increasing the platelet number. 2. In thrombocytopenic patients, MPV was decreased more than normal. 3. In various hematologic disease, MPV was decreased in acute leukemia, marrow failure and aplastic anemia, normal in iron deficiency. anemia, increased in reactive marrow, MPV was varied by platelet number in various hematologic disease. This disclosed that MPV was related with marrow function and production of megakaryocytes. From these results, MPV could be used as a valuable parameter in the evaluation of platelet together with measuring the platelet number. Particular relation-ship between MPV and various hematologic disease were not observed. We should be more study for MPV.

유산소 리듬 운동프로그램이 노인의 혈압, 심박수 및 생활만족도에 미치는 효과

우선혜,김효정,박영숙 대한보건협회 2001 대한보건연구 Vol.27 No.3

The purpose of this study was to test the effects of aerobic rhythmical exercise program on blood pressure, pulse and the life satisfaction of the elderly. This quai-experimental study was designed as a non-equivalent control group pretest-posttest study. The subjects were 36 subjects(experimental group: 19 subjects, control group: 17 subjects), aged between 65 and 73 years who have normal cognition, sensory function and cerebellum function. Aerobic rhythmical exercise program was developed on the basis of aerobic exercise, Korean tradititional dance and music by the author. The blood pressure, pulse rate and life satisfaction were measured prior to and following the experimental treatment. Data were analyzed with x^2-test, t-test, mean, standard deviation, percentage of change and ANCOVA test using SAS program. The results were as follows. 1. There was no significant difference of systolic blood pressure between experimental and control group following the aerobic rhythmical exercise program(F=1.39, P=0.247). 2. The diastolic blood pressure of the experimental group was significantly lower than that of control group following the aerobic rhythmical exercise program(F=2.96, p<0.1). 3. There was no significant difference of resting heart rate between experimental and control group following the aerobic rhythmical exercise program(F=0.07, P=0.793). 4. The life satisfaction of the experimental group was significantly higher than that of control group following the aerobic rhythmical exercise program(F=9.94, p<0.01). On the basis of the above findings, aerobic rhythmical exercise program is effective in reducing diastolic blood pressure and promoting life satisfaction of the elderly. Thus, this program can be recommended as an effective nursing intervention for the elderly.

사무공간의 통합유니트 구축을 위한 조명유니트 도출에 관한 연구

김선숙,신선준,김지현,양인호,김광우 대한건축학회 2005 대한건축학회논문집 Vol.21 No.1

The purpose of this study is to develop the lighting units for workspace and to propose their application method at the architectural design stage The lighting unit is one of the components of a workspace integrated unit, which can be defined as the planning unit satisfying the environmental comfort criteria of workspace According to the survey of current domestic and foreign office buildings, the luminaire layout types could be classified into the line, spot and square type Various simulation cases were set up considering these layout types, architectural modules, and luminaire types Finally, forty-four lighting units were developed by RADIANCE simulation With these lighting units, the designer would be able to easily predict how his decision about architectural modules influences the lighting design, and can consider other alternatives