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Zhang, Jun-Feng,Hua, Rong,Sun, Yong-Wei,Liu, Wei,Huo, Yan-Miao,Liu, De-Jun,Li, Jiao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9
Background: Perineural invasion (PNI) has been reported as one of the sources of locoregional recurrence in resected pancreatic cancer (PC). However the impact of PNI in resected pancreatic cancer remains controversial. The purpose of this study was to determine the association between PNI status and clinical outcomes. Methods: Publications were identified which assessed prognostic significance of PNI status in resected pancreatic cancer up to February 2013. A meta-analysis was performed to clarify the association between PNI status and clinical outcomes. Results: A total of 21 studies met the inclusion criteria, covering 4,459 cases. Analysis of these data showed that intrapancreatic PNI was correlated with reduced overall survival only in resected pancreatic ductal adenocarcinoma (PDAC) patients (HR=1.982, 95%CI: 1.526-2.574, p=0.000). Extrapancreatic PNI was correlated with reduced overall survival in all resected pancreatic cancer patients (HR=1.748, 95%CI: 1.372-2.228, p=0.000). Moreover, intrapancreatic PNI status may be associated with tumor recurrence in all resected pancreatic cancer patients (HR=2.714, 95%CI: 1.885-3.906, p=0.000). Conclusion: PNI was an independent and poor prognostic factor in resected PDAC patients. Moreover, intrapancreatic PNI status may be associated with tumor recurrence.
Rong-Jun Zhang,Wei-Jie Lu,Qing-Yuan Cai,Wei-Xi Zhou,Yu-Xiang Zheng,Liang-Yao Chen,Hui Zhou,Shi-Xiong Qian,Se-Young Seo 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4
The nonlinear optical properties have been studied using the Z-scan technique for silicon nanocrystals embedded in a SiO2 matrix formed by high-temperature annealing of SiOx/SiO2 superlattices grown by thermal evaporation. A mode-locked Ti:sapphire laser system producing 140-fs-long pulses at 800 nm was used as the optical source for the Z-scan measurements. The nonlinear refractive index and the nonlinear absorption coefficient of the silicon nanocrystals were found to be 1.2 × 10−13 cm2/W and 1.5 × 10−9 cm/W, respectively, and to be strongly enhanced compared to those of bulk silicon. Such enhancement of the nonlinear optical properties is considered to be due to the quantum confinement effect of silicon nanocrystals.
Study of the Optical Properties of Bi3:15Nd0:85Ti3O12 Ferroelectric Thin Films
Rong-Jun Zhang,Yi-Ming Chen,Yu-Xiang Zheng,Peng-Hui Mao,Wei-Jie Lu,Liang-Yao Chen 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.4
The optical properties of Bi3:15Nd0:85Ti3O12 (BNdT) feroelectric thin films were studied. The BNdT thin lms were deposited on Pt/Ti/SiO2/Si substrates by using a sol-gel technique. The elipsometric spectra of the BNdT thin film were measured and investigated in the photon energy range of 1.5 - 4.5 eV. The elipsometric spectral data were fited by using the four-phase layer structure model and the Forouhi-Bloomer (FB) model, which was used to describe the optical dispersion relation of the sample. The optical constants of the sample were obtained by using a data analysis based on Tauc's principle and showed that the direct band gap of the BNdT sample existed at 3.89 eV.
A Parallel Power Quality Conditioner without Harmonic Detection
Yan-jun Zhang,Zhen YANG,Sheng-fei YANG,Rong ZHANG 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
A non-harmonic detection Parallel Power Quality Conditioner (PPQC) which can compensate harmonics and reactive power without harmonic and reactive power detection is introduced. By studying the energy exchange process and principle between the AC side and DC side, a DC voltage control method, controlling the magnitude and direction of the current flowing into the DC side, is proposed, to keep the DC voltage stable. The influence of the load active current on the DC voltage is analyzed in detail. A new non- harmonic detection control strategy is proposed with the load active current as a perturbation. The proposed control strategy which avoids complex detection algorithm, and in turn the errors and delay caused by detection algorithm, improves dynamic response speed greatly. Experiment results exhibit excellent harmonic and reactive power compensation performance and dynamic response.
Yana, Rong,Zhang, Ruizhong,Zhang, Xian,Jiang, Chao,Han, Jian-Guo,Zhang, Ying-Jun Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.6
The objective of this study was to investigate the effects of different ratios of corn silage (CS): alfalfa hay (AH), and extruded soybeans (ESB) on milk yield, milk composition, blood metabolites, and fatty acids in milk fat and plasma. Ninety multiparous Holstein cows were arranged in a randomized block design experiment which lasted 14 weeks. Treatments were arranged as a $3{\times}3$ factorial with 0%, 5% or 10% ESB (dry matter basis) and three forage treatments: I) 30% CS, 10% AH and 10% Leymus chinense hay (LC); ii) 20% corn silage, 20% alfalfa hay and 10% LC; iii) 10% CS, 30% AH and 10% LC. Cows were allowed to consume a total mixed ration ad libitum. There was no change of dry matter intake when cows were fed the experimental diets. As more AH was added to the diets, milk yield, milk protein content and yield, and trans9, cis11-conjugated linoleic acids (CLA) concentrations in milk fat and plasma increased. When ESB were supplemented to the diets, milk yield, and trans9, cis11-CLA concentration in milk fat and plasma increased. When 10% ESB was added to the diet containing 30% AH the trans9, cis11-CLA content (1.46 g/100 g of total fatty acids) in milk was the highest among all treatments. These results suggests that AH could replace part of a CS diet and be a good forage source of diet for dairy cows to improve milk yield and milk composition. Meanwhile, ESB could be included in the diet with high AH to improve production performance of dairy cows.
Jun He,Li-Rong Zhou,Lei Zhang,Xiao-Ying Feng 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.4
Elevated temperature in municipal solid waste will affect the performance of earthen materials in a landfill cover liner system. Soda residue (SR), ground granulated blast furnace slag, and quicklime were utilized as solidifiers in sewage sludge, and the curing temperature effect on geotechnical behavior of solidified sludge in landfill temporary cove applications was investigated. The unconfined compressive strength, yield stress, coefficient of compressibility, hydraulic conductivity, and microstructural and mineralogical characteristics of solidified sludge at various curing temperatures were measured. Hydration products including ettringite crystals and calcium-silicate-hydrates (C-S-H) were observed in the samples. An increase in temperature from 12 to 40°C improved the solidified sludge strength, but a further increase to 60°C decreased the strength. The lowest coefficient of compressibility and the lowest hydraulic conductivity were observed at 40°C. The pore volume or pore size of the solidified sludge decreased with the increase in temperature. However, the geotechnical performance was improved due to the increase in C-S-H and decrease in ettringite in 40°C sample. 50% SR content was optimum for solidified sludge temporary cover due to its relatively high strength, high yield stress, low compressibility, moderate hydraulic conductivity, and good pollution stabilization capability at different curing temperatures.
Zhang, Qing-Mei,Shen, Ning,Xie, Sha,Bi, Shui-Qing,Luo, Bin,Lin, Yong-Da,Fu, Jun,Zhou, Su-Fang,Luo, Guo-Rong,Xie, Xiao-Xun,Xiao, Shao-Wen Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8
Melanoma-associated antigen (MAGE) family genes have been considered as potentially promising targets for anticancer immunotherapy. MAGED4 was originally identified as a glioma-specific antigen. Current knowledge about MAGED4 expression in glioma is only based on mRNA analysis and MAGED4 protein expression has not been elucidated. In the present study, we investigated this point and found that MAGED4 mRNA and protein were absent or very lowly expressed in various normal tissues and glioma cell line SHG44, but overexpressed in glioma cell lines A172,U251,U87-MG as well as glioma tissues, with significant heterogeneity. Furthermore, MAGED4 protein expression was positively correlated with the glioma type and grade. We also found that the expression of MAGED4 inversely correlated with the overall methylation status of the MAGED4 promoter CpG island. Furthermore, when SHG44 and A172 with higher methylation were treated with the DNA demethylating agent 5-aza-2'-deoxycytidine (5-AZA-CdR) reactivation of MAGED4 mRNA was mediated by significant demethylation in SHG44 instead of A172. However, 5-AZA-CdR treatment had no effect on MAGED4 protein in both SHG44 and A172 cells. In conclusion, MAGED4 is frequently and highly expressed in glioma and is partly regulated by DNA methylation. The results suggest that MAGED4 might be a promising target for glioma immunotherapy combined with 5-AZA-CdR to enhance its expression and eliminate intratumor heterogeneity.
( Zhang Yang ),( Xiao Hua Li ),( Xiao Qaing Qi ),( Jun Jie Shan ),( Rong Jiang ),( Lian Hong Guo ),( Ren Zhang ),( Yuan Li ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.11
Ebosin, a novel exopolysaccharide produced by Streptomyces sp. 139, has obvious antirheumatic arthritis activity in vivo, and its biosynthesis gene cluster (ste), consisting of 27 open reading frames, has been identified. This paper reports our study of the gene functionality of ste8, the predicted protein product of which is homologous to some bacterial chain length determinant Wzz proteins. For characterization of Ste8, ste8 was cloned and expressed in the mutant strain E. coli 086:H2 (Δwzz). The functional complementation of wzz by ste8 was demonstrated by the restoration of wild-type lipopolysaccharide biosynthesis and increased levels of serum resistance of E. coli 086:H2 (Δwzz) (pET30a-ste8). To examine the function of ste8 in ebosin biosynthesis, the gene was knocked out with a double crossover via homologous recombination. The molecular weight of the ebosin derivative EPS-8m produced by the mutant Streptomyces sp. 139 (ste8-) was much lower than that of ebosin, and the binding activity of EPS-8m for IL-1R decreased significantly compared with ebosin. These results demonstrate that ste8 encodes a chain length determinant (Wzz) that functions in ebosin biosynthesis.
Mathematical Simulation of Spray Forming Process
( Jun Fei Fan ),( Yin Zhang ),( San Bing Ren ),( You Duo He ),( Hai Rong Le ) 한국액체미립화학회 2005 한국액체미립화학회 학술강연회 논문집 Vol.2005 No.-
In this paper, an integrated approach for modeling the entire spray forming process is presented and the program for the simulation is written by hand. The whole spray forming process can be divided into four calculate process and the basis for the analysis is classical k-ε turbulence model which used to simulate the flow field of gas formed in the chamber. The other three mathematical models are atomization model,deposition model and solidification model. In the atomization model coupled the flow field of gas and formation、velocity and location of droplet. By means of integrate above mathematical model the process of spraying forming was simulated in detail.
Zhang, Cong-Hai,Yan, Sheng-Jiao,Pan, Sheng-Qiang,Huang, Rong,Lin, Jun Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.4
A series of novel chiral tert-amino alcohols 4a-h derived from enantiomerically pure phenylalanine were synthesized efficiently and used as chiral ligands in the catalytic enantioselective ethylation of aldehydes with diethylzinc (diethylzinc-to-aldehyde addition). The use of 10 mol % of the amino alcohols led to the corresponding sec-alcohols with excellent enantioselectivities (up to 100% ee) and high yields.