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      • 단무지 공장에서 발생한 질식 사고의 원인과 방사선학적 소견: 중례보고 및 가스분석 결과

        박충기,김만구,김흥철,안범규,박만수,황우철,최철순,강익원 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

        목 적:단무지 공장에서 질식사고를 일으켰던 가스의 종류를 알아내고, 이러한 가스중독의 방서선학적 소견을 소개하기 위하여 본 연구를 하였다. 대상 및 방법:단무지 공장에서 발생한 질식 사고자 3예중 생존자 1예를 대상으로 단순흥부X-선검사와 CT 소견을 분석하였으며, 가스의 종류를 알아내기 위하여 단무지를 유리병에 넣어 발생된 가스를 가스크로마토그래픽을 이용하여 분석하였다. 결 과:단무지 공장에서 발생한 질식사고자중 생존한 1명의 방사선학적 검사에서 신속히 호전되는 폐경결(consolidation)을 볼 수 있었으며 이는 폐부종의 소견임을 알 수 있었다. 협기성 상태에서 단무지를 담은 유리병의 상층부 가스를 실험 분석한 결과 이산화탄소, 에칠알코올이 다량으로 검출되었으나 독성가스는 주로 황화수소이였다. 결 론:단무지 공장의 질식 사고자에서 폐방사선학적 소견은 폐경결을 보이는 폐부증으로서 이는 실험을 통해 단무지에서 발생되는 유독가스인 황화수소 때문임을 입증하였다. Purpose: To identify the main toxic gas released from salted radish in rice bran(Dan-M-Ji) and to introduce the radiological findings of the patient who was exposed to the gas. Materials and Methods: Chest radiographs and CT scans of one survivor among three men who were exposed to the gas from Dan-Mu-Ji were reviewed. Gas obtained from the closed bottle containing Dan-Mu-Ji was analized by using the gas chromatography. Results: The radiographlc examinations of the survivor were suggestive of pulmonary edema with it's rapidly improving consolidations in both lung. The headapace gas within the bottle containing Dan-Mu-Ji was mainly composed with carbon dioxide, ethyl alcohol and hydrogen sulfide, of which hydrogen sulfide was considered the main toxic gas released. Conclusion: Under the anaerobic condition, Dan-Mu-Ji released toxic hydrogen sulfide. Inhalation of hydrogen sulfide might produce non-cardiogenic pulmonary edema.

      • 태권도선수의 호흡순환능력에 관한 연구

        박철호,김영준,김우규,박태열,홍명엽 東亞大學校附設스포츠科學硏究所 1999 스포츠科學硏究論文集 Vol.17 No.-

        The purpose of this study was to evaluate the anaerobic thresold and EPOC(Excess post-exercise Oxygen Consumption) in treadmill exercise of taekwondo players(n=7),and group of controls college students(n=7). The started treadmill exercise with speed of 120m/min and within treadmill 5% slope. Especially the treadmill speed was increased with 20m/min per two minutes and subjects were finally led to exhaustion. The results obtained from this test were as follows: 1. The VO₂max( /min), VO₂ max(kg) showed significantly higher differences taekwondo group than control group in maximum exercise. 2. The ventilation volume showed significant difference taekwondo group than control group in maximum exercise. 3. The anaerobic threshold showed significant difference taekwondo group than control group in maximum exercise. 4. The EPOC showed significant difference taekwondo group than control group in maximum exercise.

      • 묏대추나무(Zizyphus jujuba Miller)의 器官分化에 미치는 培地造成 및 生長調節物質의 影響

        朴在仁,金奎鐵 충북대학교 농업과학기술연구소 1999 農業科學硏究 Vol.16 No.-

        This experimet was carried out to establish regeneration systems of Zizyphus jujuba Miller, which will be a fundamental tool for breeding of new cultivar of Zizyphus spp. through biotechnological techniques and for in vitro physiological researches. Explants such as cotyledon segments, hypocotyl segments, epicotyl segments, internodal segments and leaves were excised from in vitro grown sterile seedlings and cultured on Woody Plant Medium(WPM) and half strength Murashige Skoog Medium(1/2MS) containing 6 kinds of growth regulators BAP, kinetin, 2iP, zeatin 2,4-D and NAA at 5 levels of 0, 0.2, 0.5, 1.0, 2.0 mg/l respectively. After 6 weeks in culture, formation and growth of shoot, root and callus were investigated. All the five kinds of explants tested showed organogenetic potentials(both shoots and roots) and callus formation by the media and growth regulator regulations, but the regeneration rate and growth were varied with the factors above. The best results in shoot regeneration were obtained when epicotyl segments were cultured on 1/2MS containing 0.2 mg/l 2,4-D(40%). and better result on WPM containing 0.2 mg/l zeatin(30%). Roots were easily formed and grown when excized leaves were cultured on 1/2MS medium containing 1.0 mg/1 NAA, where regeneration rate was 90% average root number, 5.55. Of the basal media tested for shoot regeneration in case of cotyledon and epicotyl which showed better results. 1/2MS was more efficient than WPM from cotyledons, but vice versa from epicotyls. For root regeneration, WPM was better than 1/2MS from cotyledons but vice versa from leaves. Callus formation and growth was not affected by the basal media tested. Two auxins, NAA and 2.4-D supplemented to basal media, as we know, was effective for root regeneration and callus formation. But a strange result was obtained:2,4-D supplemented to 1/2MS showed better shoot regeneration rate from epicotyls than any cytokinins. NAA promoted root regeneration and growth from all the explants tested. Of the cytokinins tested BAP and zeatin were more effective than 2iP and kinetin in shoot regeneration. Zeatin was effective in shoot regeneration from cotyledons, epicotyls and internodes. From the above results, a protocol could be suggested that epicotyls are cultured on 1/2MS media containing 0.2mg/1 2,4-D for shoot regeneration and cultured on 1/2MS medium containing NAA for rooting. For callus formation explants are cultured on WPM containing 1.0mg/1 2,4-D and the calli formed could be used for shoot regeneration and for somatic embryogenesis by further culture.

      • 동종 골수이식 후 만성 이식편대숙주질환과 동반되어 신증후군으로 발현된 IgA 신병증 1예

        정철권,김현수,박준성,정성현,조도연,최진혁,남동기,임호영,김명성,신규태,임현이,김효철 대한조혈모세포이식학회 1999 대한조혈모세포이식학회지 Vol.4 No.2

        동종 골수이식 후 발생하는 신기능부전은 원인이 다양하여 감별에 어려움이 있다. 만성 GVHD는 흉선의 기능저하에 따른 면역관용의 실패로 발생되는 자가면역현상에 의해 발생되는 것으로 알려져 있으며 드물게 신장을 침범하여 신증후군을 일으키기도 한다. CaA의 용량을 줄이거나 투약중지 후 발생한 만성 GVHD에 동반된 신증후군의 경우 조기에 신조직검사를 시행하여 감별진단하고 CsA의 용량을 증량하거나 재투약하여 좋은 치료 결과를 보일 것으로 기대된다. 저자들은 문헌고찰을 통해 동종 골수이식 후 발생된 신증후군이 유사한 임상양상을 보이며 발생기전에 만성 GVHD와 자가면역현상이 연관되어 있음을 확인하였으며 동종 골수이식 후 신증후군의 임상양상을 보이는 환자에서 병리조직학적으로 lgA 신병증을 진단하고 이러한 lgA 신병증이 발생기전에 만성 GVHD와 자가 면역현상이 연관되어 있을 가능성을 최초로 확인하였으며 CsA를 이용하여 성공적으로 치료한 경험을 하였기에 보고하는 바이다. Renal insufficiency is occasionally encountered in allogeneic bone marrow transplantation and its cause is difficult to ascertain. Chronic graft-versus-host disease (GVHD) related to thymic dysfunction is immune-mediated and involves autoreactivity of T-lymphocytes derived from donor marrow to recipient's major histocompatibility complex(MHC) minor antigens. The clinical mainifestations of chronic GVHD are similar to those of autoimmune disease but kidney involvement is rare. Few cases of nephrotic syndrome with membranous nephropathy or minimal change nephrotic syndrome have been reported to be associated with chronic GVHD in allogeneic bone marrow transplant recipient especially after cyclosporine A(CsA) withdrawal, and these cases have responded well to CsA. Therefore, it is prudent to differentiate the cause of post-transplant renal insufficiency using renal biopsy and to start CsA in a case of nephrotic syndrome associated with chronic GVHD as early as possible. We report a case who had a massive proteinuria during the post-allogeneic marrow transplantation period. The cause of nephrotic syndrome was diagnosed as IgA nephropathy by renal biopsy. The patient was successfully treated with reintroduction of CsA.

      • 상부 조기 위암 환자의 복강경하 상부 위절제술 3례 경험

        조규석,김형철,박경규,이문수,송옥평,임철완,신웅진,주종우,유기원 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Background : The reported incidence of early gastric cancer located in the upper portion of the stomach has been increasing with the recent advances in its diagnosis and screening. Recently, we have successfully performed laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without pyloroplasty on three patients with early gastric carcinoma localized to the upper third of the stomach. We describe our modification of this procedure in this report. Method : After creating an surgical pneumoperitoneum, the stomach was mobilized using laparoscopic coagulating shears. Upper half of the greater curvature and three-quarters of the lesser curvature were then dissected along with regoinal D2 lymphadenectomy. This was followed by a 5 cm, longitudinal mini-laparotomy in the upper abdomen, and the construction of the exteriorized stomach with a gastric tube measuring 20 cm long and 4 cm wide. Reconstruction with an esophagogastrostomy was performed using a circular stapler. Result : No post-operative morbidity or mortality was observed in this small series of patients. The average operative time was 250 minutes (range 220-300 minutes), and the average blood loss was 150 ml (range 90-180 ml). The mean number of lymph nodes harvested during these laparoscopic proximal gastrectomies was 24 nodes (range 22-25 lymph nodes). The average postoperative hospital stays was 7.5 days (range 7-8 days). Conclusion : Our technique of laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without phloroplasty offers a minimally invasive technique with the potential of impoving the post-operative quality of life patients with an early-stage proximal gastric cancer.

      • 레이저가공기를 이용한 SAPH400의 절단특성에 관한 연구

        조규재,박종남,이승철 朝鮮大學校 機械技術硏究所 2004 機械技術硏究 Vol.7 No.1

        본 연구의 목적은 자동차 구조용 열간 압연강(SAPH400)의 몇 가지에 대한 최적의 절단 가공 조건을 구하기 위한 실험이다. 현재 대부분의 절단가공은 기계적인 방법이 활용되고 있으며,절단속도와 정밀도,금형제작,공구수명 등의 문제점이 많아 CO₂레이저 가공기를 이용하여 이를 해결하고자 하였다. 실험은 유입가스의 압력,절단속도 및 출력의 변화를 주었을 경우 절단면의 조도와 폭에 어떤 영향을 주는가를 연구 · 분석하였다. 실험결과 출력,절단속도 및 절단가스압력을 변화시켰을 때 출력은 1500W,절단속도는 1100mm/min. 절단 가스압력은 0.5kgf/㎠마 일 때 가장 양호한 표면 거칠기 값 18.06㎛을 나타냈다. This study aims at making experiments to fine the optimum cutting processing conditions of some sheets in common use of Steel Automobile Press Hot 400(SAPH400). Current mechanical methods for cutting processing of most have several problems in relation to cutting speed, precision, manufacture of metal mold and life of tools, which we tried to solve by using the CO₂ Laser Machining. We studied and analyzed what effects on the roughness and width of a section changes in the pressure of blowing gas, cutting speed and power according to the quality and thickness of the material might exert. The results from this experimental study are summarized as follows, when power, cutting speed and gas pressure were changed, the finest value of surface roughness, 18.06㎛ was attained at power of 1500W, cutting speed of 1100mm/min and gas pressure of 0.5kgf/㎠.

      • 수직형 머시닝센타 이송시 스틱-슬립에 관한 연구

        최경현,조규재,박종남,이승철 朝鮮大學校 機械技術硏究所 2004 機械技術硏究 Vol.7 No.2

        볼나사 미끄럼 시스템에서 고속과 고정밀도를 이루는데 중대한 문제들은 마찰과 각 구성 요소들 사이에서의 마찰과 축 방향의 강성이 감소하여 나타난다 특히, 안내면에서의 마찰은 이송정밀도를 떨어뜨리는 좋지 않은 영향을 준다. 더욱이 스틱-슬립현상과 같은 특수한 마찰 형태는 미끄럼 시스템의 저 강성에서 일어난다. 스틱-슬립은 정밀도에 나쁜 영향을 가진다. 본 논문에서는 미끄럼 시스템의 정밀도에 있어서 스틱-슬립 마찰에 의한 운동오차에 따른 변화들을 고찰하여 이송정밀도의 해결 방안을 제시하려 하였다. In the ball screw slide system the major problems in accomplishing the high-speed and high-precision are the friction between elements and the decrease of axial stiffness. Especially the friction on the guide have a bad effect on the precision of sliding. Furthermore stick-slip occur when the low stiffness of slide system. The stick-slip have a bad influence on the precision. In this research, the affection of stick-slip friction to the precision of the slide system is studied and the possible solution of the precision is proposed.

      • KCI등재후보

        중환자실에 입원한 세균성 폐렴환자에서 반정량적 procalcitonin 검사의 유용성

        이승화,김철홍,김지연,박선욱,김용욱,현인규,우흥정,김현수 대한감염학회 2009 감염과 화학요법 Vol.41 No.6

        Background : In pulmonary infection, serum procalcitonin levels increase rapidly, probably in response to sepsis-related cytokine release from neuroendocrine cells of bronchial epithelium and inflammatory cells. We applied procalcitonin assay in critically ill patients with bacterial pneumonia. Materials and Methods : Patients admitted to the intensive care unit (ICU) and show diffuse infiltrations in their chest X-ray were included. Quantitative bronchoalveolar lavage (BAL) culture (≥10⁴ CFU/mL) was performed in all cases on the 5^(th) day of ICU admission. We excluded patients with structural lung disease, non-infectious lung infiltrations, and atypical infections such as Mycobacterium tuberculosis, Pneumocystis jiroveci, and viruses. Serum procalcitonin levels were measured semi-quantitatively by using PCT-Q kit. Results : A total of 28 adult patients (M:F=23:5) were included: 11 (39.3%) medically-ill patients, 7 (25%) surgically-ill patients, and 10 (35.7%) burn patients. Serum procalcitonin level was <0.5 ng/mL in half of the cases (14/28) and ≥0.5 ng/mL in the remaining half of the cases. Compared to those with serum procalcitonin level of <0.5 ng/mL, patients with serum procalcitonin level of ≥0.5 ng/mL had more frequent mechanical ventilation, higher CRP/APACHE II scores/number of organ failure (P<0.05), and showed increased tendency for death (P=0.052). Positive bacterial BAL cultures were noted in 17 cases (60.7%). Of these, 7 cases (41.2%) showed serum procalcitonin level ≥0.5 ng/mL. Conclusions : High serum procalcitonin level seems to be closely associated with the severity and poor prognosis in critically ill patients with bacterial pneumonia. However, pneumonia could not be excluded with low level of procalcitonin among ICU patients.

      • 다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

        주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

      • High-Performance Hybrid Buffer Layer Using 1,4,5,8,9,11-Hexaazatriphenylenehexacarbonitrile/Molybdenum Oxide in Inverted Top-Emitting Organic Light-Emitting Diodes

        Park, Cheol Hwee,Lee, Hyun Jun,Hwang, Ju Hyun,Kim, Kyu Nyun,Shim, Yong Sub,Jung, Sun-Gyu,Park, Chan Hyuk,Park, Young Wook,Ju, Byeong-Kwon American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.11

        <P>A high-performance 1,4,5,8,9,11-hexaazatriphenylenehexacarbonitrile (HATCN)/molybdenum oxide (MoO3) hybrid buffer layer with high hole-injection efficiency and superior plasma resistance under the sputtering process was developed. The HATCN enhances the hole-injection efficiency, and the MoO3 effectively protects the underlying organic layers from plasma damage during deposition by sputtering. This improves the characteristics of inverted top-emitting organic light-emitting diodes using a top transparent conductive oxide electrode. The device using the hybrid buffer layer showed the highest electroluminescence characteristics among devices with other buffer layers. The high hole-injection efficiency of HATCN was shown by the J-F curve of hole-only devices, and the plasma protection performance of MoO3 was shown by atomic force microscope surface morphology images of the buffer layer film after O-2 plasma treatment.</P>

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