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慢性 精神分裂病 患者의 自家 報告에 依환 社會 適應 評價; 豫備的 硏究
趙道衍 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.4
The purpose of this study was to investigate the pattern of social adjustment of chronic schizophrenics and to compare the social adjustment of chronics with that of non-psychotics and chronic medically ill patients. The self-report Social Adjustment Scale used in this study was reconstructed by reference to Social Adjustment Scale-Ⅱ, originally developed by Schooler et al. to assess the social adjustment of chronic schizophrenics.The reconstructed and modified self-report Social Adjustment Scale was administered to psychiatric outpatients including chronic schizophrenics non psychotic patients and inpatients who were suffered from chronic medical disease for at least 6 months. The result and conclusions are as follows; 1) The result showed the best social adjustment in the area of parental role and the poorest adjustment in the area of sexual adjustment in the chronic schizophrenic group. 2) In chronic schizophrenic group, the overall social adjustment was poorer than in chronic medically ill group, but there was no significant difference between chronic schizophrenic group and non-psychotic patients group. 3) Considering role function between chronic schizophrenic patients group and non-psychotic patients group showed poorer adjustment than chronic medically ill patients in the area of marital adjustment and role pwrormance in the extended family. 4) There was no significant difference between chronic schizophrenic group and non-psychotic patients group as th social adjystment. This resyult may show that chronic psychiatric patients, regardless of its diagnosis, suffer from social and vocational dysfunction.
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Circling 행동과 청력손실을 보이는 자연발증 마우스의 생물학적 특성
조도연,김명순,정원호,류재웅,홍성화 대한이비인후과학회 2004 대한이비인후과학회지 두경부외과학 Vol.47 No.2
Background and Objectives:Deafness is the most comon sensory deficit and hereditary defect in human populations. The present study investigated the causative gene in circling mice using the complementation test. In addition, the phenotypes and histopathologic findings in circler mice, spinner mice, and compound heterozygote mice were analyzed to elucidate the mechanism of causative gene in inner ear deafness. Materials and Method:In order to analyze inner ear pathology in time sequence for 10, 18, 21, 35, and 90 days old. The organs of Corti and spiral ganglion neurons in the basal and middle turns were included for quantification. For the preparation of genomic DNA, tail tissues were used. Results:The hair cells in the organ of Corti dege-nerated in a time-dependent manner. In the basal and middle turns, the volume ratio of spiral ganglion neurons significantly decreased as the mutant aged. RT-PCR analysis indicated that transmembrane iner ear (Tmie) was absent in the case of circler mice, similar to spinner mouse of which is defective Tmie gene. Therefore the variations may be a result from strain-specific Tmie gene itself (allelic heterogeneity). Conclusion:The cir mutant is a suitable mouse model for neuroepithelial defects. PCR and RT-PCR analyses suggest that the Tmie transcript is absent in circler mice. This model represents another candidate for human genetic hearing loss.
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Jonckheere-Terpstra 추세 검정통계량에 근거한 비모수적 층화분석법
조도연,양수,송혜향,Cho, Do-Yeon,Yang, Soo,Song, Hae-Hiang 한국통계학회 2010 응용통계연구 Vol.23 No.6
각 의료기관에서 수집될 수 있는 환자수가 한정되어 있는 질병의 경우에는 주로 다기관연구로써 임상연구가 진행된다. Jonckheere (1954)와 Terpstra (1952)의 추세 검정법으로 분석해야 하는 독립된 여러 군의 자료를 다기관에서 수집한 경우에 이질성을 고려하여 각 연구기관을 하나의 층으로 보아 층화분석법으로 분석하지 않으면 옳지 않은 결론에 도달할 수가 있다. 본 논문에서는 van Elteren (1960)이 제시한 Wilcoxon (1945) 검정통계량의 층화분석법을 이용하여 Jonckheere (1954)와 Terpstra (1952)의 추세 검정통계량에 근거한 층화분석법을 제시한다. 예제 자료에 이 층화분석법을 적용하며 효율성을 모의실험으로 알아본다. Clinical trials are often carried out as multi-center studies because the patients enrolled for a trial study are very limited in one particular hospital. In these circumstances, the use of an ordinary Jonckheere (1954) and Terpstra (1952) test for testing trend among several independent treatment groups is invalid. We propose a the stratified Jonckheere-Terpstra test based on van Elteren (1960)'s stratified test of Wilcoxon (1945) statistics and an application of our method is demonstrated through example data. A simulation study compares the efficiency of stratified and unstratified Jonckheere-Terpstra trend tests.
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趙道衍,李相玉 한국응용곤충학회 1963 한국응용곤충학회지 Vol.2 No.-
본 조사는 밤나무혹벌의 생태, 특히 생활사, 발생소장 및 피해에 대하여 1961-1963년에 걸쳐 경기도, 강원도 및 충청북도에서 조사한 것이다. 1. 본 충은 년 1회 발생하며 단성생식을 한다. 2. 성충의 출현은 6월 하순부터 7월 하순이며 최성기는 7월중하순이며 일중 오전중에 많이 탈출한다. 3. 성충은 출현후 곧 아에 산란하는데 1아당 4.89개를 산란하며 1개체의 포란수는 평균 198.5개이었다. 4. 란기는 30일간이며 란은 8월말까지 부화하였다. 5. 유충기간은 8월중순부터 익년 6월 중순 까지며 용기는 6월 초순부터 7월 중순까지였다. 6. 본 충은 아에 산란 기생하며 5월 하순부터 충영을 형성하여 생장을 정지시키고 율의 결실을 없게 할 뿐만 아니라 율목을 고사시킨다. 8. 본 충은 1958년 충청북도 제천에서 처음 발생된 이래 현재에는 강원도, 경기도, 충청북도의 북반부 및 경상북도북부 일부에 분포하여 가해하고 있다. The chestnut gall wasp, Dryocosmus kuriphilus , has been recently distributed and chestnut trees have teen seriously damaged by this insects in Korea. However, this insect pest has not been investigated in Korea. This paper gives an account of field and Laboratory observations on the seasonal occurrence and the life history of the chestnut gall wasp, and the damage of the chestnut trees by. its insects. This study was carried out at Chungchungpukdo, Kangwon-do and Kyungi-do in Korea, from 1961 to 1963, inclusive. 1. The Chestnut gall wasp (Dryocosmus kuriphilus ) has one generathion per year and females are only known. 2. The adult wasps were observed from late June to late July with peak of wasp emergence about early and middle July. Most of new adult wasps were coming out from, the galls in the morning rather than the afternoon. 3. Each wasp produced auerage 198.5 eggs and about 4.89 eggs was observed in each bud of the chestnut tree. 4, The egg period of wasps was about 30 days and they were hatching from July to August. 5. The larval period of wasps were from middle of August to middle of next June and pupation took places about early June to middle of July. 6. The adult wasps were ovipositing into the buds and from early May next year, galls were growing. They caused stunting of growth and no fruiting or dying of the chestnut tries. 7. The first observation of the wasp was made at Chaechun of Chungchung-pukdo in 1958. Up to 1963 this insects are distributed in Kangwon-do, Kyunggi-do, north part of Chungchung-pukdo and north part of Kyungsangpukdo
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