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조도연,이종인,변주원,김호영,정낙영,장우익,심영학,김윤미,조미연,박진숙,성기준,이종영,박승일,김은기 대한내과학회 1997 대한내과학회지 Vol.53 No.3S
Synovial sarcomas' are rare malignant neoplasms that arise from mesenchymal cells of tendosynovial tissue, accounting for about 7% of adult soft tissue sarcomas, and occur with maximal frequency in the second through fifth decades of life. The incidence of metastasis is high, most often to the lung, regional lymph nodes and bone, despite of radical surgery for primary tumor. The histologic subtypes of synovial sarcoma generally accepted are monophasic, biphasic and poorly undifferenciated types, and all synovial sarcomas have been classified as high grade soft tissue sarcoma due to high metastatic potentials by the American Joint Committee on Cancer. Spontaneous pneumothorax due to primary pulmonary neoplasm is uncommon, and pneumothorax due to pulmonary metastasis is very uncommon condition. The most common primary tumor causing spontaneous pneumothorax is sarcoma, and of these the majority are osteosarcomas. Various mechanisms have been suggested to explain how a spontaneous pneumothorax occurs as a result of pulmonary involvement of malignancy. Bilateral spontaneous pneumothorax from pulmonary metastasis of synovial sarcoma has been reported very rarely in the world literature, and has not yet been reported in Korea. We present here a very rare case of recurrent synovial sarcoma manifested as bilateral spontaneous pneumothorax, who had been treated with surgical resection and radiotherapy for the synovial sarcoma on left popliteal fossa and review the pertinent literatures.
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Jonckheere-Terpstra 추세 검정통계량에 근거한 비모수적 층화분석법
조도연,양수,송혜향,Cho, Do-Yeon,Yang, Soo,Song, Hae-Hiang 한국통계학회 2010 응용통계연구 Vol.23 No.6
Clinical trials are often carried out as multi-center studies because the patients enrolled for a trial study are very limited in one particular hospital. In these circumstances, the use of an ordinary Jonckheere (1954) and Terpstra (1952) test for testing trend among several independent treatment groups is invalid. We propose a the stratified Jonckheere-Terpstra test based on van Elteren (1960)'s stratified test of Wilcoxon (1945) statistics and an application of our method is demonstrated through example data. A simulation study compares the efficiency of stratified and unstratified Jonckheere-Terpstra trend tests.
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