심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

제주도 지하수 질산염 농도의 시·공간적 변화 특성: 장기(1993-2015) 모니터링 자료의 평가

김호림(Ho-Rim Kim),오준섭(Junseop Oh),도현권(Hyun-Kwon Do),이경진(Kyung-Jin Lee),현익현(Ik-Hyun Hyun),오상실(Sang-Sil Oh),감상규(Sang-Kyu Kam),윤성택(Seong-Taek Yun) 대한자원환경지질학회 2018 자원환경지질 Vol.51 No.1

1993년부터 2015년까지 관측된 제주도 지하수 장기모니터링 관측정(N = 4,835)에서 수집된 지하수 수질자료(N = 21,568)를 기반으로 질산성질소의 시공간적 변동 특성을 평가하였다. 제주도 지하수의 질산성질소 농도의 중앙값은 2.5 mg/L로서 다른 국가나 대륙의 조사 결과에 비해 다소 높거나 유사한 것으로 나타났다. 또한 지하수 용도, 행정구역 및 고도 별로 유의한 차이를 보였다. 특히, 산간 지역에 비해 저지대 해안가에 위치한 농업 및 주거지역에서 농도가 높음을 확인하였다. Mann-Kendall 및 Sen’s slope 분석을 활용한 질산성질소 농도의 추세 분석 결과, 하류 저지 대에 비해 중산간지역에서의 질산성질소 농도 증가 경향이 뚜렷하였다. 제주도 내 토지 피복의 시계열 변화 특성과 결부 지어 보면, 중산간지역의 오염 증가 추세는 농업지역의 확장 등 인위적 활동 증가에 기인한 결과로 판단된다. 반면,기지정된 지하수자원특별관리구역에서는 전반적으로 질산성질소 농도의 감소 경향이 나타났는데, 이는 지하수 관리 측면에서 수질관리를 위한 적극적인 정책이 유효함을 시사한다. 본 연구에서는 제주도 지하수의 질산성질소 오염관리를 위한 적정 방안을 제안한다. The spatio-temporal variations of nitrate concentrations in groundwater of Jeju Island were evaluated by an analysis of time series groundwater quality data (N = 21,568) that were collected from regional groundwater monitoring (number of wells = 4,835) for up to 20 years between 1993 and 2015. The median concentration of NO 3 -N is 2.5 mg/L, which is slightly higher than those reported from regional surveys in other countries. Nitrate concentrations of groundwater in wells tend to significantly vary according to different water usage (of the well), administrative districts, and topographic elevations: nitrate level is higher in low-lying agricultural and residential areas than those in high mountainous areas. The Mann-Kendall trend test and Sen’s slope analysis show that nitrate concentration in mid-mountainous areas tends to increase, possibly due to the expansion of agricultural areas toward highland. On the other hand, nitrate concentrations in the Specially Designated Groundwater Quality Protection Zones show the temporally decreasing trend, which implies the efficiency of groundwater management actions in Jeju. Proper measures for sustainable groundwater quality management are suggested in this study.

고령화 사회를 위한 노인의 영양서비스 요구도 조사

오유진;장유경;원선임;서종려 한양대학교 2005 韓國 生活 科學 硏究 Vol.25 No.1

The survey conducted by individual interviews. Subjects were adults aged 60 and over, recruited from three elderly schools in N city in Kyung-gi province(n=95). In the survey, subjects were interviewed for general characteristics, interesting nutrition topics, preferred methods of nutrition service. Subjects were interested in topics such as ‘anything about nutrition’(41%), ‘healthy eating’(31%), ‘diet with taking medicine’(17%), and ‘nutrition counseling’(12%). As methods of nutrition service, Subjects wanted primarily to use lectures in school(27%). Nutrition education program(29%), booklets(25%) were other commonly cited methods. These results provide baseline information for developing nutrition service and methods for elderly.

연결어미 '-어다가'

오경진 연세대학교 한국어학당 2002 외국어로서의 한국어교육 Vol.27 No.-

Teaching Korean as a Foreign Language, 27, 205∼218. This paper's purpose is to analyze the meaning of conjunctive ending '-아(어,여)다가' when adverbial ending '-아(어,여)' is combined with '-다가'. In this paper, I tried to find out what kind of verbs are used with '-어다가' and proposed five categories of syntatic restrictions. In chapter 3, the meaning of '-어' in the context of '-어다가' is presented and I interpreted it a 'the continuing state of a certain finished situation'. And in chapter 4, I suggested the verbs which is connected to '-어다가' seems to be more related with syntatic restrictions than with basic attributes of the verbs. Finally, chapter 5 deals with the five categories of syntatic restrictions about '-어다가'. 1) '-어다가' can not be connected all the action verbs but be connected some of transitive verbs. 2) Subject entity in the first sentence and the second sentences should be the same. The subject entity with '-어다가' needs animate implications as a doer. 3) The object in the sentences which is connected with '-어다가' should be the same or the object of the first sentence can be the source of the second sentence. 4) The contents of the first sentence becomes the method of the second sentence when the sentences are connected with '-어다가'. 5) The place of the first sentence should differ from the one of the second sentence. (Yonsei University)

저빈도 반복성 경두개 자기자극이 정상인의 시각적 단기 기억에 미치는 영향

오해정,김원,이경욱,박원명,전태연,한진희,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequencyr TMS on visual short term memory. Methods : Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results : No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion : This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiathc fields without any interference of cognitive function.

초내식성 스테인리스강 선재와 브라켓의 내식성 및 금속 이온 용출 특성

오근택,정경진,황충주,박용수,김경남 大韓齒科器材學會 2001 대한치과재료학회지 Vol.28 No.4

Metallic orthodontic appliances are known to release metal ions in an oral cavity. It is not advisable that toxic corrosion products derived from the appliances is absorbed into the body. Metal ions release from orthodontic appliances is known to have large effects on the result of orthodontic treatment and systemic health. Metal bracket and wire were made of super stainless steel(S32050) with high corrosion resistance. The corrosion resistance and ion release property of S32050 and conventionally used appliances were examined. Four types of wire were ligated in either super stainless steel(SB) or Tomy bracket(TB) with O-ring, and then each group was immersed in an artificial saliva at 37℃ for 12 weeks. Amount of released metal ions was measured with immersion time by graphite furnace atomic absorption spectroscopy and surface morphology was investigated. S32050 showed the low passive current density of about 1 μA/㎠ and the stable passive region to a high potential in artificial saliva. S32050 appliances did hardly release nickel ions in artificial saliva. S32050 wire(SRW) and NiTi wire(NW) didn't show significant difference of Ni ion release with immersion time, meanwhile, Remanium wire(RW) showed significant difference in 12 weeks. Ni ion releasce from the brackets didn't show any significant difference with immersion time and between SB and TB. Amounts of Ni ion released from TB-SRW showed significant difference in 12 weeks, those from TB-RW showed significant difference from 4 weeks later and highest release among all groupsin12weeks. TB-NW released little Ni ion for all immersion time and showed significant difference from 4 weeks later, TB-TW(TMA wire) showed significant difference in 12 weks. SB-SRW didn't show any significant difference and SB-RW signigicant difference in 12 weeks,but lower compared with TB group. SB-NW and SB-TW didn't show any significant difference. Corrosion products didn't be observed in mostly groups during the immersion time, except that in TB-RW, they were observed on the bracket surface between O-ring and wire from 8 weeks later. Super stainless steel wire had good corrosion resistance compared with stainless steel wire, and it is believed that it can be used as orthodontic material for bracket and wire.

중·고등학교 아랍어 교재 집필 및 교재 내용에 관한 연구 보고서

오명근,송경숙,전완경,사희만,이규철,조희선,정규영,최진영 한국아랍어아랍문학회 1999 아랍어와 아랍문학 Vol.3 No.1

(±)-Camphor가 ICR 마우스 수컷의 간 cytochrome P450 효소 활성에 미치는 영향

오은경,박형건,배기현,최옥진,최은경,최창근,한진희,정태천 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

Effects of (±)-camphor on liver cytochrome P450 enzymes were investigated in male ICR mice. Mice were treated intraperitoneally with 0, 200, 400 and 800 mg/kg of (±) -camphor in corn oil for 3 consecutive days. Twenty four hr after the final treatment, the animals were subjected to necropsy. The activities of serum aspartate aminotransferase and serum alanine aminotransferase were slightly changed by the treatment with (±)-camphor at the doses used. Administration o(±)-camphor to mice significantly induced the hepatic activities of pentoxyresorufin O-depentylase and benzyloxyresorufin O-debenzylase and weakly induced ethoxyresorufin O-deethylase in dose-dependent manners. The present results suggested that (±)-camphor might act as a relatively specific inducer of hepatic cytochrome P450 213 in male ICR mice.

모근세포의 분리배양과 발모촉진 활성에 대한 연구

오수진,조경혜 서울여자대학교 자연과학연구소 2007 자연과학연구논문집 Vol.19 No.-

The purpose of this study was to establish culture system of dermal papilla (DP) cells which thought to play an essential role in the induction of new hair follicles and the maintenance of hair growth and to investigate the effect of Schizonepeta tenyifotia Briq. and Scutellaria baicalensis Georgi. extracts on maintenance of anagen phase of DP cells. DP cells were isolated from the back skin of the newborn rats and were shown a large round shape at immediately after isolation. The cells were attached to the culture plate with monolayer and fallen with 70-80% confluency on day 4. In order to confirm DP cell biomarkers of the isolated and cultured cells, the gene expression of versican and nexin was analyzed by RT-PCR. The result showed that both genes were highly expressed and DP cell marker enzyme, alkaline phosphatase activity also was strongly increased in these isolated and cultured cells. The effects of the Schizonepeta tenyifolia Briq. and Scutellaria baicalensis Georgi. extracts on the hair-induction ability of cultured DP cells were examined. Because these extracts increased mRNA expression level of VEGF and versican in a dose-dependent manner, these extracts may be involved in inducing or maintaining anagen phase of hair cells. When DP cells were treated with these extracts, the mRNA expressions of IGF and KGF were also upregulated more than that of minoxidil treatment. These results suggest that these extracts may be candidates for helping hair growth promotion. In addition, when DP cells were treated with plant extracts mixture, VEGF and versican mRNA expression was synergistically increased.

루소의 敎育思想이 現代體育에 주는 意味

진윤수,김경오 忠南大學校體育科學硏究所 2003 體育科學硏究誌 Vol.21 No.1

The purpose of study was to review the influences of Rousseau's educational thought on the current physical education. For the purpose of this study, a through literature search based on identified in an extensive review of Emile and related literature was performed. Objectives, contexts, and methods of physical education, ideal teacher, and ideal student are reviewed within the related literature. According to Rousseau's thoughts, objectives of physical education are to develop the various organic systems of the body through physical activity in the environment so students will respond in a healthful way to the increased demands placed on them. The contexts of physical education for child contain recreation and outdoor activities that can provide them play opportunities to benefit them physically(physical fit), psychologically(hardship), and socially(faire, friendship, cooperation). The contexts of physical education for youths contain physical activity, work, and game that can provide opportunities to develop physical fitness. His teaching method was 'everything according to nature'. The laws of nature dictate to the teacher and to the student the logical pattern of growth and development(five stages). Rousseau was a strong believer in discipline. He felt that in order to create good children, discipline is a must. Rousseau also suggested that teachers let kids think that they are in control, and develop where the child naturally chooses to do well. Rousseau suggested that a teacher must have many different learning experiences. He also stressed that a teacher should have the abilities of understanding the law of nature and kid's growth and development. Most irnportantly, a teacher, by setting a good example can and will greatly influence a student's behavior and overall performance. Rousseau also felt that each student has the right to pursue freedom and happiness. It falls largely onto the teacher to find the way to help the student reach his or her potential for intelligence. Rousseau also mentioned that students should learn from experience and that students are exceptional imitators. The purpose of physical education, according to Rousseau was to develop all the child's abilities freely, as nature intended. In Rousseau's view, nature was the primary teacher and the job of the "tutor" was to be a guiding force. In Rousseau's naturalism, exploration of one's capabilities and interest leads directly to greater skills and adjustments to nature. Rousseau regarded physical activity as important, it was body, mind, and knowledge. Through physical activities, the individual develops in an all-around way.