Moon, Yoon-Hee

문윤희,권영창,정인철,이형걸 慶星大學校 1995 論文集 Vol.16 No.2

Frozen beef loin imported from Australia was stored as 2℃ after thawing, then evaluate to improvement of raw meat aroma and palatability of cooked meat by sensory evaluation. To improvement of raw meat aroma and palatability of cooked meat of thawed beef were confirmed for the reason of conditioning after thaw as a result of myofibrillar fragmentation index(MFI) and Mg-ATPase activity of myofibril. Sensory evaluation of raw meat aroma and tenderness on frozen imported beef loin stored at 2℃ after thawing had good in all during cold storage, MFI and Mg-ATPase activity increased, therefore frozen beef loin could recognized to conditioning during stored at 2℃ after thawing. Cold storage after thawing of frozen imported beef loin can improve its cooked aroma and tenderness in case that insufficient conditioning is the reason for its low palatability, and the improvement of palatability on the cooked meat appeared to be greater in aroma than taste. In case of amino acid composition, aspartic acid, threonine, glutamic acid and alanine of imported beef loin stored 7 days after thawing were showed significantly(p<0.05) higher than that stored 0 day after thawing, total amino acid composition of imported beef loin stored 0,3 and 7 days after thawing were 148.40, 171. 06 and 188.99mg/g, respectively.

여성 복압성요실금에 대한 Tension-free Vaginal Tape(TVT) 수술 성적

문찬,강윤일,김경영,문형윤,노준,김철성 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Background: We wanted to evaluated the long term results of the tension-free vaginal tape (TVT) Procedure for treating strss urinary incontinence in women. Method: During Octover 1, 1998 to December 31, 2005, we evaluated the 52 women who underwent the TVT procedure for stress urinary incontinence at least 1 year following surgery. Preoperatively, Patients were evaluated with history taking, Physical examinations and urodynamic study, Operation and hospitalization data were evaluated with duration of procedure, hospital days, foley catheter removal days and use of analgesics, Postoperative evaluations included the uroflowmetry, residual urine volume, surgical outcomes, complications and patients' satisfaction with the procedure. Results: The follow-up period was a mean of 16 months. Preoperative I-QoL total score was 58.0. Comparision the result between preoperative and postoperative Q max was significantly shoter in the postoperative result. TVT procedure remained cure in 96.2% (cured: 82.7%, improved: 13.5%) and successful in 96.1%. Also, 49(94.2%) Patients would like to recommended the TVT procedure to others. There was no serious or long-term complications, Conclusions: The TVT procedure appear to be effective and safe for the surgical treatment of female stress urinary incontinence and showed a good long-term cure rate.

고공 및 지상 방사능 측정 성적에 관한 소고

차재철,문형남,김형철 공군본부 의무감실 1970 항공의학 Vol.18 No.1-2

Mirizzi 증후군의 변형된 분류와 치료

김형철,강길호,채만규,김성용,백무준,이문수,박상흠,이문호,김창호,송옥평,조무식,박희주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Purpose : The Mirizzi syndrome is relatively rare and preoperative diagnosis of this disease is difficult. In 1978, Morelli suggested the subclassification of the Mirizzi syndrome into acute or chronic form. We experienced 5 cases of acute form. We analysed clinical features, preoperative radiologic findings and operative findings of 18 cases including acute forms which were diagnosed as Mirizzi syndrome and should suggest the modified classification of Mirizzi syndrome for choice of appropriate treatment. Method : From January 1995 to December 1998, 18 cases, of which 8 cases were diagnosed at Soonchunhyang University Chunan Hospital, and 10 cases were reported in the Korean Journal were retrospectively analysed with regard to clinical features, preoperative radiologic findings and operative findings. According to the clinical features, whole cases were divided into type Ⅰ(acute form) and type Ⅱ(chronic form) and then each type of cases were subclassified according to preoperative radiologic findings and operative findings. Results : Of 18 cases there were 5 cases in type Ⅰ(27.8%), 13 cases in type Ⅱ(72.2%). Type Ⅱb was most common. Type Ⅰa cases were treated only with cholecystectomy. We applied cholecystectomy, T-tube choledochostomy and patch technique in type Ⅰb and thpe Ⅰc cases. Cholectystectomies including removal of gallstones and internal drainage procedures were done in type Ⅱ chronic forms. Conclusion : The acute form(Type Ⅰ) of Mirizzi syndrome was suggested by Morelli might be subclassified into typeⅠa,Ⅰb and Ⅰc following the presence of the necrotic defect in common hepatic duct. Through the modified classification of Mirizzi syndrome based on clinical feature, preoperative radiologic findings and operative findings, we can choice appropriate treatment.

지난 2년간의 학회지 "신경정신의학" 심사 평가보고

김찬형,김세주,김도관,김성곤,박원명,송동호,박용천,이영문,오강섭,정영철,이상열,김주한,이동영,이헌정,함병주,김율리,김문두,김정진,이강욱,천근아,김재진,홍진표,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

부대동맥 림프절 또는 쇄골상부 림프절에 국한된 전이가 있는 재발성 자궁경부암 환자들의 예후에 관한 연구

최석철,문형배 동국대학교 의학연구소 1998 東國醫學 Vol.5 No.-

자궁경부암에서 림프절 전이가 병소의 재발이나 환자의 예후에 악영향을 미친다는 것은 주지의 사실이다. 그러나 자궁경부암으로 일차치료 후에 재발한 자궁경부암 환자들 중에서 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해서는 잘 알려져 있지 않다. 따라서 본 연구는 자궁경부암으로 근치적 전자궁적출술 및 골반림프절 절제술이나 방사선치료 후에 재발한 환자들 중 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해 알아보고자 하였다. 1991년 1월부터 1995년 12월 까지, 원자력병원 산부인과에서 자궁경부암으로 일차치료 후 전산화 단층촬영 및 세침흡인 세포검사에서 부대동맥 및/혹은 쇄골상부 림프절전이가 증명된 재발성 자궁경부암 환자 55명을 대상으로 하였다. 1. 대상환자 55례 중 부대동맥 림프절에 국한된 전이가 있었던 경우는 31례(56.4%)였으며, 쇄골상부 림프절에 전이가 있었던 경우는 24례(43.6%)였다. 쇄골상부 림프절에 전이가 있었던 24례 중 8례는 쇄골상부 림프절에 국한된 전이가 증명된 경우(Supraclavicnlar lynph node : SCLN only군)였고, 나머지 16례는 부대동맥 림프절 및 쇄골상부 림프절에 전이가 동시에 있는 경우(both군)였다. 2. FIGO 임상병기별 분포는 Ⅰ기 9.1%, Ⅱ기 56.4%, Ⅲ기 32.7%, Ⅳ기 1.8%였다. 세포형태에 따른 림프절 전이율은 편평상피세포형이 96%(53/55)였다. 대상환자 55례 중 22례(40.0%)는 일차치료 당시 이미 골반림프절에 전이가 있었던 경우였다. 대상 환자들의 원발암 치료는 방사선 치료만을 시행 받은 경우가 60.0%(33/55), 방사선 치료와 항암화학요법을 시행 받은 경우가 18.2%(10/55), 수술 및 방사선 치료, 항암화학요법을 시행 받은 경우가 18.2%(10/55), 그리고 수술 및 방사선 치료를 시행 받은 경우가 3.6%(2/ss)였다. 3. 전체 연구대상 환자 55례의 3년 생존율은 14.4%이었으며, 부대동맥 림프절전이군과 쇄골상부 림프절전이군의 3년 생존율은 각각 15.4%, 10.7%이었고, SCLN only군 및 both군의 3년 생존율은 각각 0%, 19.7% 이었다. 결론적으로, 쇄골상부 림프절 전이가 있는 환자는 부대동맥 림프절에 국한된 전이가 있는 환자보다 3년 생존율이 낮음을 알 수 있었으며, 이에 따라 재발성 자궁경부암 환자에서는 쇄골상부 림프절의 전이 유무가 환자의 예후를 추정하는데 중요한 지표가 될 것으로 생각되었다. It is evident from previous reports that in patients with cervical cancer with metastases to lymph nodes have unfavorable outcome, there are, however, few reports have previously been made of the clinical characteristics and prognosis of patients with metastasis limited to para-aortic lymph nodes(PALN) only versus supraclavicular lymph nodes(SCLN) following primary treatment. This paper attempts to discuss the outcome of Patients with recurrent cervical cancer metastasis limited to these lymph nodes. This report is a retrospective analysis of 55 patients with recurrent cervical cancer metastasis limited to para-aortic or supraclavicular lymph nodes following radical hysterectomy or definitive radiation therapy treated at the Korea Cancer Center Hospital, from January 1991 through December 1995. The results were as follows. 1. Of the 55 patients entered, 31(56.4%) had positive nodes on para-aortic area only and 24(46.3%) had positive nodes on supraclavicular area. 8 of 24 patients had limited metastasis to SCLN only and 16 had metastatic nodes on both para-aortic and supraclavicular area. 2. The distribution of patients according to initial FIGO stage were 9.1% in stage Ⅰ, 56.4% in stage Ⅱ, 32.7% in stage Ⅲ, and 1.8% in stage Ⅳ. In 96.4%(53/55) of cases, the histologic type was a squamous cell carcinoma. 22(40.0%) of 55 patients had pelvic lymph node metastasis at the time of initial treatment. The distribution of patients by treatment modalities prior to recurrence was 60.0%(33/55) for patients treated with radiotherapy alone, 18.2%(10/55) for patients treated with combined chemotherapy and radiotherapy, and 18.2%(10/55) for patients treated with combined surgery, radiotherapy, and chemotherapy. 3. The overall 3-year survival rate for patients with positive nodes on para-aortic or supraclavicular area was 14.4%; those who had lymph nodes limited to para-aortic only achieved 15.4%; those who had lymph nodes limited to supraclavicular lymph node achieved 10.7%. Of these, those who had nodes on supraclavicular lymph node only or both supraclavicular and para-aortic lymph node achieved 0% and 19.7% 3-year survival rate, respectively. In conclusion, the outcome for patients with metastasis to supraclavicular lymph nodes was worse than for patients with metastasis to para-aortic lymph nodes only. This suggest that the presence of metastatic carcinoma on supraclavicular lymph node may be a reliable Predictor of probability of survival in such patients.

방광에 발생한 염증성 근섬유아세포종

강윤일,문형윤,노준,김철성 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Inflammatory myofibroblastic tumor of urinary bladder is a rare benign entity that clinically and radiologically simulates a malignant tumor. This benign lesion must be differentiated histoloeically from several malignant lesion of the bladder. Complete surgical excision, either by transurethral resection or partial cystectomy, appears to be curative. We report a case of inflammatory myofibroblastic tumor of the urinary bladder in a 25-year-old female.

당밀의 첨가가 갈근탕박 사일리지의 품질과 산양의 기호성에 미치는 영향

김성복,문계봉,이봉덕,오홍록,배형철,이수기 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.1

Two experiments were conducted to investigate the effects of molasses supplementation to silage materials in ensiling Galgeuntang (herbal medicine) meal on the quality of silage, and its palatability in Korean native goats. In experiment Ⅰ, molasses was added at the levels of 0, 0.5, and 1.0% to Galgeuntang meal with three replicates per treatment. In experiment Ⅱ, three 1.5-yr-old Korean native goats were used to measure palatability. In experiment Ⅰ, lactic acid contents in molasses treatments were significantly(p<0.05) higher, and pH and butyric acid contents were lower than those of non-molasses treatment. In addition, molasses treatment increased total microbial cell counts in MRS medium for lactobacillus, but decreased total microbial cell counts in PDA medium for fungi. Molasses supplementation to silage materials increased in vitro dry matter disappearance. Molasses supplementation tended to increase silage intake in Korean native goat (experiment Ⅱ), but the difference was not significant(p>0.05). It is concluded that molasses supplementation to silage materials in ensiling herbal medicine meal could improve its preservability and palatability, the higher the better.

후복막강경 근치적 신적출술 : 개복 근치적 신적출술과의 비교

김경영,임동훈,문형윤,노준,김철성 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

Purpose: Although kidney is located in the retroperitoneal space laparoscopic radical nephrectomy is usually performed by the transperitoneal approach. At our institution the retroperitoneal approach is preferred. We evaluated the surgical outcomes, safety, oncologic outcomes, and compared with the results those of open radical nephrectomy in a contemporary cohort. Materials and Methods: Between January 2000 and December 2005 we performed retroperitoneal laparoscopic radical nephrectomy for renal cell carcinoma in 37 patients with clinical stage cT1 and cT2. Data from the these patients were retrospectively compaired with 30 contemporary cases treated with open radical nephrectomy. The clinical parameters including perioperative outcomes, complications, pathologic data, learning curve and recurrence were evaluated. Results: For the 37 retroperitoneal radical nephrectomies mean tumor size was 4.6cm (range 2.3 to 8.0), surgical time was 203.6min (range 110-410) and blood loss was 241.8cc. Mean specimen size was 10.4cm (8.7-14.4). Mean analgesic used day was 1.3 (0-4) and mean postoperative hospital stay was 4.2 days. minor complications occur in 16 cases and no major complications occurred. Surgical margins were negative for tumor in all patients. Variable parameters were comparable between patients undergoing laparoscopic and open radical nephrectomy. However, laparoscopy resulted in decreased blood loss, surgical times, analgesia use, time to oral intake, time to drain removal and postoperative hospital stay. No different complication rate is between two groups Conclusions: Retroperitoneal laparoscopic radical nephrectomy can be a safe and effective treatment in renal cell carcinoma. Although no long-term follow-up is available, our follow up to mean 31 months confirm the effectiveness of retroperitoneal laparoscopic radical nephrectomy in terms of surgical principles and oncological effectiveness.

동결온도가 해동 쇠고기의 품질에 미치는 영향

남주현,송형익,김미숙,문윤희,정인철 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

동결온도가 해동우육의 품질에 미치는 영향을 검토하였다. 해동드립감량은 -3℃ 동결이 30일째에 3.4%, -20℃ 동결이 60일째에 1.8%로 높았으며, -3℃가 -20℃보다 드립량이 많았다. 가열감량은 water bath와 pan 가열 모두 저장초기보다 동결저장중에 현저하게 높았으나, 동결온도에 의한 차이는 없었다. 염용성 단백질의 추출성은 동결기간이 경과함에 따라 감소하였고, -20℃에서 동결한 것이 -3℃에서 동결한 것보다 추출성이 높았다. 수용성 단백질의 추출은 -3℃의 경우 동결기간에 따라 현저한 변화가 없었으나, -20℃에서 동결한 것은 동결기간에 따라 증가하는 경향을 보였다. 명도(L)는 동결초기가 높았고 적색도(a)는 동결기간에 따른 변화가 없었으며, 황색도(b)는 동결초기보다 동결중에 더 높았다. Myoglobin의 변성율은 -3℃의 경우 45일째, -20℃의 경우 15일째 각각 94.4%와 94.0%로 가장 높았다. 전단력가는 동결초기보다 저장기간이 경과함에 따라 높아졌으며, 근원섬유의 소편화도는 동결저장중 현저한 변화가 없었다. pH는 -3℃와 -20℃ 모두 30일째까지 높아지다가 그 이후 낮아지는 경향을 나타내었다. This study was carried out to investigate the effects of freezing temperature on quality of thawed beef loin. In case of thaw drip loss, the freezing of -3℃ and -20℃ were higest by 3.4% to 30 days and by 1.8% to 60 days, respectively. And the thaw drip loss of -3℃ freezing was more than -20℃ freezing. The cooking loss of water bath and pan boiling were increased significantly during freezing than the beginning of freezing, but were not different -3℃ and -20℃. The salt soluble protein extractability was decreased during freezing, the -20℃ freezing was higher than -3℃ freezing. The water soluble protein extractability of -3℃ freezing was not significant different during freezing storage, that freezed at -20℃ was increased during freezing. The "L" value of the beginning of freezing was higher than during freezing, the "a" value was not different during freezing, and the "b" value during freezing was higher than the beginning of feezing. The myoglobin denatured percentaged of the -3℃ and -20℃ freezing were highest by 94.4% to 45 days and by 94.0% to 15 days, respectively. The shear force value during freezing was higher than the beginning of freezing, the myofibrillar fragmentation index was not significant different during freezing. The pH was increased to freezing 30 days, after that was decreased.