크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

Discordance in Spirometric Interpretations Based on Korean and Non-Korean Reference Equations

Nami Kim,Mi-Hee Park,Se-yeong Kim,Chunhui Suh,Sangyoon Lee,Kun-Hyung Kim,Chae-Kwan Lee,Dae-Hwan Kim,Jong-Tae Lee 대한직업환경의학회 2013 대한직업환경의학회지 Vol.25 No.-

Objectives: Korean regression models for spirometric reference values are different from those of other ethnic groups. The purpose of this study was to evaluate discordance in spirometric interpretations based on using Korean reference equations versus non-Korean reference equations. Methods: Spirometry was performed on 825 Korean male workers from April 2009 to November 2011. The spirometric patterns and disease severity were evaluated using two Korean equations (Choi’s and Lee’s) and three equations for Caucasians (NHANES III, Morris’s, and Knudson’s), and the results of Choi’s equation were compared with the non-Korean equations. The spirometric patterns were defined as normal, restrictive, and mild and moderate obstructive. Results: The mean differences in the FEV1% and FVC% between the two Korean equations were 2.0 ± 1.3% and 3.5 ± 2.2%, respectively. Morris’s equation had the greatest difference in the FEV1% from Choi’s equation: 32.9 ± 8.5%. Knudson’s equation had the greatest difference in the FVC% from Choi’s equation: 10.5 ± 6.5%. Conclusions: The two Korean equations shared similar characteristics of spirometric interpretation. The spirometric interpretations of Choi’s equation were significantly different from those of Morris’s equation and Knudson’s equation.

한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

주방용품에 대한 소비자구매 실태조사

이종영,김선희 경북대학교 1992 논문집 Vol.24 No.-

Because of the progress of import liberalization and the rising labor cost, Korean kitchen ware are losing competitive power, like other industries in Korea. More and more the korean consumers are exposed to foreign products and various domestic brands which are competing indomestic kitchen were market. As a result, Korean firms face with more difficult situations. This situation requires Korean firms to adop different marketing strategies. It is necessary that the Korean ware firms adopt cosumer oriented marketing strategy. This study attempts to analize consumer behavior regarding kitchen ware. The main findings of research shows that consumer attitude is drastically changing. That is, there are clear difference between 20∼30 year old housewives and 40∼50 year old housewives in their attitude toward kitchen ware. ◁표 삽입▷ (원문을 참조하세요) The Younger consumers prefers kitchen ware made of stainless. And they prefer department stores, and other one-stop shoppings that have many items in one place. They acquire information from advertising and relatives. They are not so much concerned with high price and use import goods more than older generation. Accordingly, Marketing strategy of kitchen ware will have to decide which segment to target and focus on consumer oriented marketing in that target market.

지방산, 지방 알코올 및 프로필렌글리콜이 클렌부테롤의 경피투과에 미치는 영향

이영대,권기철,정시영,이종달,용철순 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-

Clenbuterol, a selective β_(2)-adrenergic receptor stimulant, has been introduced as a potent bronchodilator for patients with bronchial asthma, chronic bronchitis and pulmonary emphysema. For the purpose of developing a transdermal preparation for clenbuterol, we attempted to select an optimal solvent system and permeation enhancer among fatty acids and fatty alcohols which are known to accelerate the penetration of various drugs in permeation experiments using hairless mouse skin and Franz diffusion cell. Apparent partition coefficient of clenbuterol was increased as pH of buffer solution was increased and solubility of clenbuterol was increased as the percent of propylene glycol(PG) in buffer solution(pH10) was increased. Permeability of clenbuterol from different buffer(pH 10)/PG solvent mixtures was decreased as the percent of PG in pH 10 buffer solution was increased and among the various enhancers studied, lauryl alcohol was found to be the most effective enhancer, increasing the permeability of clenbuterol approximately 76-fold compared with control. Lauryl alcobol(0-2%) enhanced the permeability of clenbuterol concentration-dependently. In this study, the optimal solvent system for the penetration of clenbuterol was found to be 50/50 buffer(pH 10)/PG solvent mixture containing 2% lauryl alcohol.

플라즈마 표면처리 기법에 의한 무기절연물 표면상의 젖음성 향상에 관한 연구

이종호,엄무수,황영한 울산대학교 1994 공학연구논문집 Vol.25 No.2

본 연구는 유리섬유 강화 복합재료(GFRP)의 최적제작조건을 규명하기 위한 기초연구로서, 플라즈마 발생장치의 최적조건을 규명하고, 에폭시 수지와 유리섬유 사이의 계면현상을 표면처리 조건에 따라 각각 접촉각 변화과정을 측정하였다. GFRP의 필라(filler)표면처리는 열처리, 실란 결합제 처리, 플라즈마 처리를 했고 플라즈마를 발생시키기 위한 주위환경은 공기로 했다. 표면처리 한 무기절연물 표면에서 에폭시 수지상의 접촉각은 표면처리 조건에 따라 다르게 나타났고 특히, 플라즈마 처리시간과 전기로 내부 주위온도에 크게 영향을 받고 있음을 알 수 있었다. 본 연구에서 플라즈마 처리시간과 전기로 내부 주위온도의 관점에서 80℃일때는 3분, 100℃일때는 4분, 120℃일때는 5분일때 접촉각 특성이 가장 우수하게 나타남을 알 수 있었다. With the contact angle of phase epoxy resin on the inorganic filler(glass plate) surface treated with air plasma, we have studied about the interface between epoxy resin and glass plate as a simple model of glass fiberreinforced composite materials(GFRP). The contact angle on the inorganic filler surface varied with surface treatment conditions . The contact angle significantly depends on plasma treating time and environment temperature of the oven. From the view point of plasma treatment condition in this work, optimum treatment time were proved as 3, 4 and 5 minutes for the treatment temperatures of 80℃, 100℃ and 120℃, respectively.

소나무와 리기다소나무의 수간류 및 수관통과우의 화학적 성질

이상덕,이명종,주영특 강원대학교 삼림과학연구소 2001 Journal of Forest Science Vol.17 No.-

수간류, 수관통과우의 화학적 성질변화에 미치는 수종간 차이의 영향을 비교하기 위하여 강원대학교 구내의 소나무림과 리기다소나무림을 대상으로 하여 조사, 분석하였다. 임의우의 평균 pH는 6.2였으며, 소나무의 수관통과우>소나무의 수간류>리기다소나무의 수관통과우>리기다소나무의 수간류 순의 평균 pH값을 보였다. 또한 6월을 제외한 대부분의 조사기간 동안 임의우의 pH가 수간류와 수관통과우의 pH보다 높게 나타났다. 다른 원소에 비하여 양이온은 Ca2+과 K+이, 음이온은 NO3-과 SO42-이 타원소에 비하여 높게 나타났으며, 특히 11월에 K+, Mg2+, Na+이 증가하였다. 한편, 소나무와 리기다소나무의 수간류와 수관통과우에 있어서의 용존원소 농도는 임외우 보다 높게 나타났다. This research was carried out to investigate the effects of the different tree species (Pinus densiflora and Pinus rigida) about the chemical properties of stemflow and throughfall at Chuncheon city in Kangwon province. The water quality of the rainfall, stemflow and throughfall in each forest stands were analyzed chemically. The pH average of precipitation was pH 6.2 and pH averages were throughfall of P. densiflora> throughfall of P. rigida> stemflow of P. rigida during the study period. During the all period, the pH of precipitation was higher than the pH of stemflow and throughfall except on June. The concentration of cation(Ca2+ and K+) and anion(NO3- and SO42-) were higher than others. Especially on November, the concentration of K+, Mg2+, Na+ were increased. The concentration of dissolved elements of stemflow and throughfall (Pinus densiflora and Pinus rigida) were higher than precipitation. Key words : precipitation, stemflow, throughful, Pinus densiflora, Pinus rigida,

인슐린 비의존성 당뇨병에 동반된 심상성 천포창 1 례

이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.

장애인 입소시설과 특수학교의 구강건강관리 실태에 대한 조사 연구

이광희,김대업,하순영,박종석 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

전국의 123개 장애인 입소시설과 102개 특수학교를 대상으로 구강건강관리 실태를 파악하여 장애인의 구강건강관리 계획을 수립하는 데 사용할 수 있는 근거를 마련하고자 하였다. 설문지 조사법으로 연구하였다. 정기구강검진은 특수학교에서 연2회 실시하고 있었으나, 장애인 입소시설에서는 56.8%에서 시행하였다. 우식 예방 프로그램은 장애인 입소시설의 69.1%, 특수학교의 86.3%에서 시행하였으며 프로그램의 종류는 입소시설에서 규칙적 칫솔질이 58.1%, 특수학교에서 예방교육이 65.7%로 가장 많았다. 불소를 이용한 우식예방은 입소시설과 특수학교에서 각각 8.6%, 11.8%에서 시행하고 있었으며, 열구전색은 각각 6.8%, 6.9%에서 시행하였다. 치과치료를 시행하고 있는 입소시설과 특수학교에서는 각각 84.2%, 39.2%이었고, 입소시설에서 치료를 받기 위해 이용하는 곳은 치과의원(60.2%), 보건소(16.8%), 자원봉사자(15.3%), 대학병원(1.0%) 등이었다. 치료를 위해 치과의원에 방문하여 치료를 거부당한 경험이 있는 응답자는 17.7%이었다. 주요어 : 장애인, 입소시설, 특수학교, 정기구강검진, 우식예방, 치과치료. The purpose of study was to investigate the oral health care status in institutions and special schools for the disabled in Korea. Nurses in 123 institutions and nurse-teachers in 102 special schools were asked to fill questionnaires regarding periodic oral examination. preventive dental programs, and dental treatment. The results of this study were as follow. 1.56.8% of institutions implemented regular oral examinations and all of special schools did it twice a year. 2.Preventive programs for dental caries were done in 69.1% of the institutions and 86.3% of the special schools. Programs included regular toothbrushing and dental health education. 3.Dental treatment was done in 84.2% of the institutions and 39.2% of the special schools. Institutions utilized private dental clinics(60.2%), public health centers(16.8%), volunteers(15.3%), and dental hospitals. 4.17.7% of the institutions experienced the refusal to treat the disabled by private dental clinics.

건드릴가공의 절삭성에 대한 연구〔Ⅰ〕

李守鍾,鄭英得,朴相福 釜山工業大學校 1990 論文集 Vol.32 No.-

Gundrilling is a key process in deep hole machining which for example, occupye 20~30 percentage on the mild die machining. Recently, according to popularization of NC machine and machining center, Gundrilling's high efficient processing is powerfully required. This paper deal with enperimental research on the machinahility of gundrilling. We obsersed on the cutting power and variety of machined hole diameter in case various materials such as SM20C SM45C SUS304 and gundrill's configurations and cutting oil. The main results are obtained as follows : 1. Machining torque and thrust are well approached MILTON C, SHAW'S theorectical eq. at feed range 0.015~0.02mm/rev. 2. Total machining condition is good at feed range 0.015~0.02mm/rev. 3. Mean hump ratio is founded 1.47~16 in torque 1.03~2.27 in thrust. 4. When gundrill's cutting angle is near 30。-20。removal chip is normally formed.