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      • 볼엔드밀 가공시 원통경로에 따른 형상특성에 관한 연구

        조병무,유익수,이동주 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

        The free-formed surface machining using a ball end mill is important and the geometric accuracy of a 3D workpiece is effected by the cutting characteristics. Machining error is defined by the normal distance between designed surface and actual tool path with tool deflection. This is inevitably caused by the tool deflection, tool wear, thermal effect and machine tool errors and so forth. The results will be useful as a guidance for cutting condition to improve the geometrical accuracy of free-formed surface in ball end milling.

      • 볼엔드밀 가공에서 형상정밀도에 관한 실험적 연구

        조병무,유익수,이성휘,이동주 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

        In manufacturing process, the. free-formed surface machining using a ball end mill of CNC machining center is important and the geometric accuracy of a 3D workpiece is effected by the cutting characteristics. Machining error is defined the normal distance between designed surface and actual tool path with tool deflection. This is inevitably caused by the tool deflection, tool wear, thermal effect and machine tool errors and so forth. In this study, the geometric accuracies such as roundness in semi-cylinder, free-formed profile and surface roughness were measured using a Coordinate Measurement Machine(CMM) and a contact type surface roughness measuring device. The results will be useful as a guidance for cutting condition to improve the geometrical accuracy of free-formed surface in ball end milling.

      • <i>Eimeria</i> species in cattle with diarrhoea in the Republic of Korea regarding age, season and nature of diarrhoea

        Lee, Seung-Hun,Kim, Ha-Young,Lee, Haeseung,Kim, Jong Wan,Lee, Yu-Ran,Chae, Myeong Ju,Oh, Sang-Ik,Kim, Jong Ho,Rhee, Man Hee,Kwon, Oh-Deog,Goo, Youn-Kyoung,Kim, Tae-Hwan,Geraldino, Paul John L,Kwak, Do BMJ Group Group Ltd 2018 The Veterinary record Vol.183 No.16

        <P>This study evaluated the prevalence of <I>Eimeria</I> species, particularly <I>E bovis</I>, <I>E zuernii</I> and <I>E auburnensis</I> that are pathogenic to cattle, in faecal samples collected from cattle with diarrhoea reared in the Republic of Korea by using microscopy and PCR. In addition, the prevalence of <I>Eimeria</I> species was analysed according to age, type of cattle, region, season and nature of diarrhoea. Overall, <I>Eimeria</I> species were identified in 279 of the 1261 (22.1 per cent) faecal samples through microscopy, and statistical analysis revealed a lower prevalence in calves aged than three weeks or less and higher prevalence in cattle with haemorrhagic diarrhoea. Of the 279 microscopy-positive samples, <I>E bovis</I>, <I>E zuernii</I> and <I>E auburnensis</I> were identified in 100 (7.9 per cent), 83 (6.6 per cent) and 27 (2.1 per cent) faecal samples, respectively, by using PCR. To the authors' knowledge, this study is the first to apply PCR for epizootiology of bovine coccidiosis.</P>

      • A Safety and Feasibility of Laparoscopic Left Side Liver Resection

        ( Ju Ik Moon ),( In Seok Choi ),( Jung Seok Lee ),( Sang Eok Lee ),( Nak Song Sung,),( Si Min Park ),( Dae Sung Yoon ),( Won Jun Choi ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: Laparoscopic liver resection has become an alternative method for managing various liver tumors in the worldwide. However, the safety of laparoscopic liver resection still remains controversial. The aim of this study was to evaluate feasibility and a safety of laparoscopic left side liver resection based on 60 cases of laparoscopic liver resections in a single center. Methods: Between Jan. 2005 and Sept. 2016, 60 patients underwent laparoscopic left side liver resections at Konyang University Hospital, Daejeon, Korea. The following characteristics and results were retrospectively evaluated through the medical records. Results: A total of 60 cases were included in this study. The mean age of patients was 61.3 ± 11.0 years. The operations were performed left hemihepatectomy (LH) (n = 33, 55.0%), left lateral sectionectomy (LLS) (n = 27, 45.0%). During the follow periods left hemihepatectomy and left lateral sectionectomy were performed for IHD Stone (n = 37), HCC (n = 9), metastasis (n = 5), cholangiocarcinoma (n = 5), biliary cystadenoma (n = 2), hemangioma (n = 1) and angiomyolipoma (n = 1). Operative time was 318.4 ± 118.9 min and 217.5 ± 85.8 min in LH and LLS. A tendency of gradually decreased transecting time was observed in the left hemihepatectomy (R2 = 0.295; p < 0.001). There was no conversion to open surgery and no mortality. Complications occurred in the 6 (10.0 %) patients during the follow periods. Conclusions: According to our results, laparoscopic left hemihepatectomy and left lateral sectionectomy are safe and feasible procedures. We believe that laparoscopic left side liver resection has become the standard method for managing various liver tumors and diseases.

      • SCOPUSKCI등재

        Alto ShooterTM 로 조절된 말기 신부전증 환자에서의 다발성 표재성 위전정부 출혈

        이상인,이준희,박효진,강진경,한기준,박인서,이세준,정준표,문병수,이관식,송기섭,손주익 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.6

        Diffuse or multifocal superficial gastrointestinal bleeding can be treated by endoscopic laser, argon plasma coagulation, heater probe, or electrocoagulation. However, these methods need relatively expensive equipments and clinical experience. Recently, Alto Shooter (Kaigen Co, Ltd, Osaka, Japan) which can spray 100% sodium alginate was developed to control gastrointestinal bleeding as a topical therapy. We herein present a 47-year-old man with end stage renal disease in whom multiple superficial gastric antral bleeding was successfully managed by the use of Alto Shooter. This method is easy and relatively cheap to use and seems to control superficial bleeding effectively from vascular lesions or after endoscopic biopsy.

      • Dihydrobenzofuran Norlignans from the Leaves of Cedrela sinensis A. Juss

        Lee, Ik-Soo,Kim, Hong-Jin,Youn, Ui-Jung,Chen, Quan-Cheng,Kim, Jin-Pyo,Ha, Do Thi,Ngoc, Tran Minh,Min, Byung-Sun,Lee, Sang-Myung,Jung, Hyun-Ju,Na, Min-Kyun,Bae, Ki-Hwan WILEY-VCH Verlag 2010 Helvetica chimica acta Vol.93 No.2

        <P>Two new norlignans, cedralins A (1) and B (2), were isolated from the leaves of Cedrela sinensis. Their structures were established by extensive spectroscopic studies and chemical evidence. The absolute configurations of these compounds were determined by comparing their CD spectra with those of known compounds. In addition, their in vitro cytotoxic activity against two human-cancer cell lines was evaluated.</P> <B>Graphic Abstract</B> <P> <img src='wiley_img/0018019X-2010-93-2-HLCA200900180-content.gif' alt='wiley_img/0018019X-2010-93-2-HLCA200900180-content'> </P>

      • A Light Scattering Layer for Internal Light Extraction of Organic Light-Emitting Diodes Based on Silver Nanowires

        Lee, Keunsoo,Shin, Jin-Wook,Park, Jun-Hwan,Lee, Jonghee,Joo, Chul Woong,Lee, Jeong-Ik,Cho, Doo-Hee,Lim, Jong Tae,Oh, Min-Cheol,Ju, Byeong-Kwon,Moon, Jaehyun American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.27

        <P>We propose and fabricate a random light scattering layer for light extraction in organic light-emitting diodes (OLEDs) with silver nanodots, which were obtained by melting silver nanowires. The OLED with the light scattering layer as an internal light extraction structure was enhanced by 49.1% for the integrated external quantum efficiency (EQE). When a wrinkle structure is simultaneously used for an external light extraction structure, the total enhancement of the integrated EQE was 65.3%. The EQE is maximized to 65.3% at a current level of 2.0 mA/cm(2). By applying an internal light scattering layer and wrinkle structure to an OLED, the variance in the emission spectra was negligible over a broad viewing angle. Power mode analyses with finite difference time domain (FDTD) simulations revealed that the use of a scattering layer effectively reduced the waveguiding mode while introducing non-negligible absorption. Our method offers an effective yet simple approach to achieve both efficiency enhancement and spectral stability for a wide range of OLED applications.</P>

      • 만성골수성백혈병에서의 동종골수이식 : 국내 경험의 후향적 분석 Retrospective Analysis of Korean Experience

        이규형,이제환,이정신,김상희,김우건,김춘추,이종욱,김병국,박선양,이홍기,윤성수,김효철,남동기,한지숙,민유홍,현명수,황태주,정익주,박영석,이정애 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.2

        연구방법: 국내에서 시행된 만성골수백혈병의 치료를 위한 가족간 동종골수이식의 임상적 특징을 후향적으로 분석하였다. 9개의 병원에서 1986년 9월부터 1997년 6월까지 시행한 137예의 가족간 동종골수이식을 보고하였다. 결과: 전체 환자 중 62%인 85예가 남자였고 연령은 15세에서 50세까지 분포하였다(중앙치 30세). 95예(71%)의 환자는 이식 당시 만성골수성백혈병 만성기의 상태였고 38예(28%)는 가속기 또는 모세포성발증기의 상태였다. 70예(51%)의 환자는 이식전처치로 busulfan+cyclophosphamide (BuCy) 치료를 받았고 42예(31%)의 환자는 cyclophosphamide+전신방사선 조사(Cy-TBI)를 받았다. 환자에게 이식된 단핵구의 수는 0.06-9.5×10^(8)/kg(중앙치 1.2×10^*/kg)였다. 1 예를 제외한 모든 환자에서 이식 후 8-100일(중앙치 17일)에 중성구 500/㎕ 이상의 착상이 관찰되었다. 급성 및 만성이식편대숙주질환은 각각 46%와 43%의 환자에서 관찰되었다. 중앙추적기간 20개월(범위 3-135개월) 경과 후 137예의 환자 중 52예의 환자가 사망하였다. 사망 원인은 감염(27%), 백혈병의 지속 또는 재발(23%), 이식편대숙주질환(21%), 치료독성(15%), 그리고 이식편거부(8%) 등이었다. 환자들의 event-free survival에 영향을 주는 인자로는 이식전 병의 상태(p<0.001)와 환자의 혈청 HBsAg 양성여부(p=0.012)가 중요하였다. Overall survival에 영향을 주는 인자도 이식전 병의 상태와 환자 혈청 HBsAg 양성여부로 나타났다. 결론: 본 연구에서 국내 만성골수성백혈병에 대한 동종골수이식술은 그 시행 예가 급격히 증가하고 있음을 보여주었다. 환자들의 임상 특성과 생존 성적은 외국의 성적과 유사하였다. B형 간염 감염환자의 경우 예후가 유의하게 불량하였고, 이는 추후의 임상연구에서 확인이 필요한 소견으로 사료된다. Background and Methods: Clinical features of allogeneic bone marrow transplantation (BMT) performed for patients with chronic myelocytic leukemia (CML) in Korea were analyzed retrospectively. Nine hospitals reported a total of 137 cases of allogeneic BMT performed between September, 1986 and June, 1997. Results: There were 85 male (62%) and 52 female patients with median age of 30 years (range 15-50). Ninety five patients (71%) were in chronic phase and 38 patients (28 %) were in accelerated/blastic phase of the disease. Seventy patients (51%) received busulfan-cyclophosphamide (BuCy) regimen for preparation and 42 patients (31%) received cyclophosphamide-total body irradiation (Cy-TBI) regimen. The median mononuclear cell dose given to patients was 1.2×10^(8)/kg (range, 0.06-9.5×10^(8)/kg). All but one patient achieved absolute neutrophil count of 500/μl after median 17 days after BMT (range, 8-100 days). Acute and chronic graft-versus-host disease (GVHD) were reported in 61/133 (46%) and in 57/134 (43%) patients, respectively. The median follow-up time of survivors was 20 months (range, 3-135 months). There were 52 deaths (38%). The causes of death were infection (14 patients, 27%), recurrent/persistent disease (12 patients, 23%), GVHD (11 patients, 21%), regimen related toxicity (8 patients, 15%), graft rejection/failure (4 patients, 8%), and unknown (3 patients, 6%). The factors influencing event free survival of the patients were disease status before BMT (p<0.001, by log-rank test) and serum hepatitis B surface antigen status (p=0.012). Longer duration of disease before BMT showed poorer outcome but the difference did not reach statistical significance. The factors affecting overall survival of the patients were disease status before BMT (p=0.009) and hepatitis B surface antigen status (p=0.036). The donor hepatitis B antigen status did not influence event free survival or overall survival of the patients. Conclusion: Clinical features and survival patterns of patients with CML treated with allogeneic BMT in Korea were similar to historical data from other countries. Further data analyses are warranted for the role of hepatitis B virus infection influencing the outcome of allogeneic BMT for CML.

      • A Study on the Noise Reduction of Reciprocating Type Air Compressors

        Lee Kwang-Kil,Kim Kwang-Jong,Lee Gwan-Hyung,Park Jae-Suk,Son Doo-ik,Kim Bong-Ki,Lee Dong-Ju The Korean Society of Safety 2004 International Journal of Safety Vol.3 No.1

        This paper deals with the noise evaluation technique of a reciprocating air-compressor and its noise reduction. The reciprocating air-compressors are widely used in the small, medium sized industrial firms, and lots of their employees are affected and irritated by their noise in the workplace. Thus, noise control actions should be taken appropriately by considering the hearing loss due to the occupational noise exposure. Lead-wrapping techniques are employed to identify the contribution of principal noise sources which are generally known as motor, belts, suction/discharge valves, moving pistons, and flow-induced noise caused by edges or discontinuities along the flow path e.g. expansions, contractions, junctions and bends etc .. As a result, main noise sources of the air-compressor can be categorized by the suction/discharge noise, valve noise, and compressed-air tank noise. Based on the investigations, mufflers are designed to reduce both the suction/discharge noise and the compressed-air tank noise. Instead of the conventional valve plate, polyethylene resin is used as a new one for the reduction of valve impact noise. In addition, attempts are made to reduce the valve noise propagation to the cylinder head and the compressor tank by using the insulation casings. As a result of the countermeasure plans, it can be achieved that the noise reduction of the air-compress is up to 10dB.

      • SCIEKCI등재

        A Single Center`s 30 Years` Experience of Esophageal Adenocarcinoma

        (Ju Ik Son),(Hyo Jin Park),(Kee Sup Song),(Ki Joong Kim),(Chang Youl Lee),(Sang In Lee),(In Suh Park) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.4

        N/A Background: Adenocarcinoma of the esophagus has been reported to be increasing in incidence in a number of regions throughout the world, while the incidence of squamous cell carcinoma (SCCA) of the esophagus is mostly stable or decreasing. To evaluate the increasing tendency of adenocarcinoma of the Methods: we studied retrospectively the records of patients with histologically proven esophageal cancer between 1970 and 1999 at the Yonsei Medical Center. Results: Total cases of esophageal cancer were 969 patients of which the cases of adenocarcinoma and SCCA were 27 patients and 918 patients, respectively. The ratio of esophageal adenocarcinoma to SCCA was 0.0375 in the 1970s, 0.0241 in the 1980s and 0.0292 in the 1990s. There was no statistical difference (p=0.811) in the ratios of adenocarcinoma of the esophagus between the three consecutive 10-yeargroups. Conclusion: In conclusion, unlike the US and other western countries, it seems that the ratio of esophageal adenocarcinoma compared to SCCA has not increased among patients with esophageal carcinoma at the Yonsei Medical Center.

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