제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

A Study on FIFA Partner Adidas of 2022 Qatar World Cup Using Big Data Analysis

Kyung-Won Byun 한국인터넷방송통신학회 2023 International Journal of Internet, Broadcasting an Vol.15 No.1

The purpose of this study is to analyze the big data of Adidas brand participating in the Qatar World Cup in 2022 as a FIFA partner to understand useful information, semantic connection and context from unstructured data.Therefore, this study collected big data generated during the World Cup from Adidas participating in sponsorship as a FIFA partner for the 2022 Qatar World Cup and collected data from major portal sites to understand its meaning. According to text mining analysis, ‘Adidas’ was used the most 3,340 times based on the frequency of keyword appearance, followed by ‘World Cup’, ‘Qatar World Cup’, ‘Soccer’, ‘Lionel Messi’, ‘Qatar’, 'FIFA’, ‘Korea', and ‘Uniform’. In addition, the TF-IDF rankings were ‘Qatar World Cup’, ‘Soccer’, ‘Lionel Messi’, ‘World Cup’, ‘Uniform’, ‘Qatar’, ‘FIFA’, ‘Ronaldo’, ‘Korea’, and ‘Nike’. As a result of semantic network analysis and CONCOR analysis, four groups were formed. First, Cluster A named it ‘Qatar World Cup Sponsor’ as words such as ‘Adidas’, ‘Nike’, ‘Qatar World Cup’, ‘Sponsor’, ‘Sponsor Company’, ‘Marketing’, ‘Nation’, ‘Launch’, ‘Official’, ‘Commemoration’ and ‘National Team’ were formed into groups. Second, B Cluster named it ‘Group stage’ as words such as ‘Qatar’, ‘Uruguay’, ‘FIFA’ and ‘group stage’ were formed into groups. Third, C Cluster named it ‘Winning’ as words such as ‘World Cup Winning’, ‘Champion’, ‘France’, ‘Argentina’, ‘Lionel Messi’, ‘Advertising’ and ‘Photograph’ formed a group. Fourth, D Cluster named it ‘Official Ball’ as words such as ‘Official Ball’, ‘World Cup Official Ball’, ‘Soccer Ball’, ‘All Times’, ‘Al Rihla’, ‘Public’, ‘Technology’ was formed into groups.

Association of 20 potential ATP2B1‐interacting genes with blood pressure in Koreans

Kyung‐Won Hong,Hyun‐Seok Jin,Ji‐Eun Lim,Bermseok Oh 한국유전학회 2011 Genes & Genomics Vol.33 No.3

Plasma membrane calcium‐transporting ATPase 1 (ATP2B1)is associated significantly with blood pressure in Caucasians and Asians. ATP2B1 regulates calcium homeostasis and belongs to the P‐type calcium pump family; several studies have identified diverse proteins that bind to ATP2B1. We hypothesized that ATP2B1 regulates blood pressure through ATP2B1‐interacting genes. To this end, 20 potential ATP2B1‐interacting genes were selected, 197 SNPs of which were analyzed for their association of systolic and diastolic blood pressure. These 20 genes were categorized into 2 groups: ATP2B1‐binding genes and ATP2B1‐cleaving calpain family members. Three ATP2B1‐binding genes (CALM1, NOS1, and PDLIM1)were associated with blood pressure, and a SNP in CALM1(rs2401887) generated the strongest association signal (beta=‐3.60±0.92, p=8.9×10^(‐5) for systolic blood pressure and beta=‐1.40±0.62, p=0.02 for diastolic blood pressure). Of the calpain family members, 3 genes (CAPN6, CAPN9, and CAPN10)were associated with blood pressure, and the CAPN10 SNP rs4676348 yielded the strongest association signal (beta=‐0.88±0.27, p=0.001 for systolic blood pressure and beta=‐0.58±0.18, p=0.015 for diastolic blood pressure). Further, the interaction of CALM1 to ATP2B1 was examined using the blood pressure of individuals who carried both variants of CALM1and ATP2B1 genes. Similarly the interaction of CAPN10 to ATP2B1 was also examined. The CALM1 variant (rs2401887)and CAPN10 variants (rs4676348) appear to decrease blood pressure further in addition to the decrease by the variant (rs17249754) of ATP2B1, which suggests that ATP2B1 might regulate blood pressure through the ATP2B1‐interacting genes CALM1 and CAPN10.

정신분열병환자의 뇌량에 대한 신경병리적 고찰 : 확산텐서영상(Diffusion Tensor Image)기법의 적용

이경진,신용욱,하태현,이종민,김인영,김선일,문원진,정은철,박해정,오정은,박지영,강경훈,권기원,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.4

Objectives : Diffusion tensor imaging (DTI) is a new technique that can be used to visualize and measure the diffusion of water in brain tissue. It is particularly useful for evaluating white matter abnormalities. In this paper, we investigated the neuropathology of the corpus callosum in patients with schizophrenia through the new methods, diffusion tensor imaging. Methods : Diffuse tensor imaging was performed in 19 schizophrenic patients and 26 healthy controls. One complementary measure, fractional anisotropy (FA), which is considered to be sensitive indices of axonal integrity, was obtained from regions of interest in the five areas of the corpus callosum. Neuropsychological measurement also underwent for measurement of frontal lobe function in two groups. Results : There were no significant differences of FA in the DTI measures for either the schizophrenic patients compared with controls. FA was significantly decreased in women compared with men. Neuropsychological measurements such as Wisconsin card sorting test were correlated with FA of patients with schizophrenia. Conclusion : FA measures revealed no differences between schizophrenia and controls. The findings suggest that the structural integrity of white matter in patient with schizophrenia was not disrupted. The results are discussed in relation to previous studies reporting positive and negative findings. It is concluded that further studies using DTI in larger samples, improved and standardized methods of data acquisition and analysis are needed.

P247 : A study on use of complementary and alternative medicine for acne

( Sook Kyung Lee ),( Taek Geun Lee ),( Hyun Hwang Bo ),( Tae Gwang Kwon ),( Se Won Jung ),( Young Seok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Complementary and alternative medicine (CAM) is any practice that has healing effects, but is not based on evidence demonstrated by scientific method. Recently, CAM has been used in various diseases including acne. However, there have been no studies on CAM for acne in Korea. Objectives: The purpose of this study was to analyze the use of CAM in acne patients. Methods: A total of 159 patients with acne were enrolled on the study, and filled out a questionnaire about use of CAM. Results: Overall 87.4% (139/159) of the patients reported the previous or current use of at least one more type of CAM. Cosmetics for acne (100, 22.9%) was most frequently used, followed by diet therapy (81, 18.5%), spa and bath therapies (77, 17.6%), health food supplement (67, 15.3%), skin care shop (64, 14.6%), oriental medicine (38, 8.7%), and aromatherapy (9, 2.1%). The most common reason for using CAM was ``wish to try everything`` (28.6%), and the most common source of information was internet (40.5%). The therapeutic effect of CAM was best with diet therapy (32.1%). The most common side effect of CAM was aggravation of symptoms. The most common monthly cost for CAM was between 50,000 and 100,000 won/person. Conclusion: As our results, we can predict that the use of various types of CAM for acne will become more common. Therefore, dermatologists need to study about benefits and adverse effects of CAM for acne.

Angiotensin Concerting Enzyme 유전자의 유전적 다형성(Genetic Polymorphism)이 관상동맥 질환 위험인자에 따른 혈중 Plasminogen Activator Inhibitor-1의 농도에 미치는 영향

김덕경,김종원,권현절,류재춘,박승우,김준수,이상훈,홍경표,박정의,이원로 대한고혈압학회 1996 대한고혈압학회지 Vol.2 No.2

청소년 일탈행동 예방을 위한 사회정서학습의 특징과 교육적 함의

손경원 ( Kyung Won Son ),이인재 ( In Jae Lee ) 한국윤리교육학회 2009 윤리교육연구 Vol.0 No.19

청소년 문제가 날로 심각한 사회문제가 되고 있다. 본 연구는 청소년 문제의 효과적인 해결 방안을 모색하기 위해 사회정서학습(SEL)의 이론적 배경 및 실제 사례를 분석하여, 한국의 예방교육의 개선방향을 모색하였다. 사회정서학습은 사회 정서적 유능성을 길러, 단기적으로는 청소년이 당면하는 문제들을 발달적으로 적합하게 해결하도록, 장기적으로 책임있고 건전한 시민으로 성장하도록 기여하는 데 있다. 따라서 자신과 타인의 감정 인식과 조절, 친사회적 문제해결 기술을 기르는 데 중점을 둔다. 이러한 기술들은 문제 행동을 유발할 수 있는 개인의 기질적 위험요인이나 환경의 위험요인이 미치는 부정적 효과를 줄이거나 상쇄하는 보호하는 요인으로서 작용한다. 기술의 학습에서는 기술에 대한 이해와 지식만큼이나 반복적 실천이 중요하기 때문에, 교육에 적합한 환경조성이 중요하다. 그러므로 사회정서학습은 문제행동을 보이는 학생을 선별한 프로그램 교육보다 모든 학생들을 대상으로 한 예방 교육을 강조한다. 최근 청소년 문제를 해결하기 위해, 문제 행동을 보이는 청소년에게 문제해결기술 함양을 목표하는 사후적 상담 프로그램이 실시되고 있다. 이러한 조치가 보다 효과적이려면, 모든 학생들을 대상으로 한 예방교육이 동시에 이루어져야 하며, 보다 장기적으로 실시되어야 하며, 정서적 유능성과 관련된 정서 인식 및 조절에 대한 기술의 교육이 보완되어야 한다. 이를 위해 본 연구에서는 사회정서학습을 도덕과 교육의 내용요소로 통합하는 일이 하나의 대안이며, 이는 도덕과 교육의 효과성뿐 아니라 청소년 문제 해법의 효과성을 높일 것이라고 주장하였다. It has been more and more increasing worry about how to solve youth problems like violence, bullying drug abuse, drop out. This study is investigate to Social and Emotional Learning and suggest it`s implication on the korean education in order to effectiveness of the treatment and prevention of adolescents problems. SEL helps young people to be grown up with healthy and as responsible citizen. This is the reason why SEL tries to give importance to "understanding and control self and other`s emotion" as well as responsible decision making skill. Social and emotion skills works resilience elements in spite of risk element adolescents might meet. SEL tries to build good circumstance which students exercise their learned skills in the class whole day, and then SEL had better every student targeted program than indicated prevention program. In other hand, it has been implementing indicated prevention program in the Korea. That is enough efficient to help youth prevention because these program is too short, not for every student and doesn`t include emotion intelligence. This study suggests that SEL has to integrate in the moral education. That policy will be made win-win situation in prevention education as well as moral education on the side of education efficiency

십이경근(十二經筋)과 근육(筋肉)과의 관계(關係)에 대한 연구

심원보 ( Won Bo Sim ),김용득 ( Yong Deuk Kim ),안영남 ( Young Nam An ),김경식 ( Kyung Sik Kim ),손인철 ( In Chul Sohn ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.20 No.2

The Oriental Medicine is described with so many terms of its own theory causing misunderstand of the concept which is expressed with same term used in modern medicine. Muscular system is also used in the both medicines, the Oriental Medicine and modern medicine. For the purpose of resolving the misunderstand of using the medical terms, we referred to a large number of literature for the muscular system in both medicine. Although there are few references concerning about systematic components in the Oriental Medicine, among the concepts of the Oriental Medicine, there are comparatively many approaches to the Meridian muscular system, a muscular system related with the Meridian, Therefore, there are many similarities and differences in the interrelation between the muscular system which was stated at the time of the concept of the Meridian system was developed and anatomical muscular system in the modern medicine. As a result of survey the references, we found out that anatomical muscular system is limited to visual compartments, whereas the Meridian muscular system is covering not only visual components but also the relation with internal organs. We conclude that there are conceptual differences in the kyung-keun system in the past and anatomical muscular system in the present.

東醫壽世保元 臟腑論에 대한 考察

李敬愛,朴性植,李源哲 동국대학교 한의학연구소 1995 東國韓醫學硏究所論文集 Vol.4 No.-

The purpose of this study is to understand a term of 'Jangbu theory 臟腑論' in 'Dong-Eui-Su-Se-Bo-Won 東醫壽世保元' . The conclusion would be summerized as follows. 1.'Jangbu theory 臟腑論' of 'Sa-Sang medicine 四象醫學' is based on 'Sa-Sang structure 四象構造' . 2.'Mind 心' of 'Sa-Sang medicine 四象醫學' is recognised as the Lord of body. 3.'four-Jang 四臟' and 'four-Bu 四腑' constitute 'Sa-Sang structure 四象構造' which is based on the deviation of 'vital energy 氣', and 'four-Jang 四贓' plays a loading role. 4.'Sacho 四焦' explaine the whole function of human body including one's heart's desire, physical constitution and the visceral physiology. 5.'ear-eye-nose-mouth 耳 目 鼻 口' is connected with 'the profound secrets of nature 天機' and also has a close relation with creation of 'spirit-vital energy-blood-essence 神氣血精' and spiritual function. 6.'SaHae theory 四海論' of 'Dong Mu 東武' is philosophical concept set on the basis of 'nature 天性' and 'life 入命'. 7.'spirit-vital energy-blood-essence 神氣血精' doesn't have the relation of mutual transformation. It's creation and consumption lies on 'the power of ear-eye-nose-mouth 耳目鼻口之力'. 8.'Sa-Sang medicine 四象醫學' expands its theory centering on the deviation of 'vital energry 氣'and the transversaa circulation of 'SaHae 四海'. According to the above result, 'Jangbu theory 臟腑論' in 'Dong-Hui-Su-Se-Bo-Won 東醫壽世保元' should be understood on the basis of' Sacho 四焦' and 'SaHae 四海' according to 'Sa-Sang structure 四象構造' , accompanying philosophical thinking focused on human and society, the centural concept of 'Jangbu theory 臟腑論' could be said as' Mind 心' to be the Lord of body.

사상체질과 신체형태지수와의 연관성

박경아,김희진,허경석,안수경,이성호,이종은,이원택 대한췌담도연구회 2000 대한췌담도연구회지 Vol.5 No.4